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2012
35 Citations (Scopus)

Endothelin b receptors contribute to retinal ganglion cell loss in a rat model of glaucoma

Minton, A. Z., Phatak, N. R., Stankowska, D. L., He, S., Ma, H. Y., Mueller, B. H., Jiang, M., Luedtke, R. T., Yang, S., Brownlee, C. & Krishnamoorthy, R., 20 Aug 2012, In : PLoS ONE. 7, 8, e43199.

Research output: Contribution to journalArticleResearchpeer-review

Endothelin Receptors
glaucoma
endothelins
Retinal Ganglion Cells
Endothelins
30 Citations (Scopus)

Estrogen prevents oxidative damage to the mitochondria in Friedreich's ataxia skin fibroblasts

Richardson, T. E., Yu, A. E., Wen, Y., Yang, S. & Simpkins, J. W., 3 Apr 2012, In : PLoS ONE. 7, 4, e34600.

Research output: Contribution to journalArticleResearchpeer-review

Friedreich Ataxia
Mitochondria
Fibroblasts
skin (animal)
estrogens
45 Citations (Scopus)

Methylene Blue as a Cerebral Metabolic and Hemodynamic Enhancer

Lin, A. L., Poteet, E., Du, F., Gourav, R. C., Liu, R., Wen, Y., Bresnen, A., Huang, S., Fox, P. T., Yang, S. & Duong, T. Q., 9 Oct 2012, In : PLoS ONE. 7, 10, e46585.

Research output: Contribution to journalArticleResearchpeer-review

methylene blue
Methylene Blue
Hemodynamics
hemodynamics
Brain
36 Citations (Scopus)

Neuroprotection targeting ischemic penumbra and beyond for the treatment of ischemic stroke

Liu, R., Yuan, H., Yuan, F. & Yang, S., 1 Jun 2012, In : Neurological Research. 34, 4, p. 331-337 7 p.

Research output: Contribution to journalReview articleResearchpeer-review

Stroke
Therapeutics
Vascular Dementia
Neuroprotection
Cellular Structures
80 Citations (Scopus)

Neuroprotective Actions of Methylene Blue and Its Derivatives

Poteet, E., Winters, A., Yan, L-J., Shufelt, K., Green, K. N., Simpkins, J. W., Wen, Y. & Yang, S., 31 Oct 2012, In : PLoS ONE. 7, 10, e48279.

Research output: Contribution to journalArticleResearchpeer-review

neuroprotective effect
methylene blue
Methylene Blue
chemical derivatives
Derivatives
17 Citations (Scopus)

Neuroprotective effects of high affinity sigma 1 receptor selective compounds

Luedtke, R. T., Perez, E., Yang, S., Liu, R., Vangveravong, S., Tu, Z., MacH, R. H. & Simpkins, J. W., 2 Mar 2012, In : Brain Research. 1441, p. 17-26 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Neuroprotective Agents
Haloperidol
Stroke
sigma Receptors
Pentazocine
54 Citations (Scopus)

Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway

Ryou, M. G., Liu, R., Ren, M., Sun, J., Mallet, R. T. & Yang, S., 1 Apr 2012, In : Stroke. 43, 4, p. 1101-1107 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Erythropoietin
Reperfusion Injury
Brain Ischemia
Pyruvic Acid
Hypoxia-Inducible Factor 1
15 Citations (Scopus)

Transient Focal Cerebral Ischemia Induces Long-term Cerebral Vasculature Dysfunction in a Rodent Experimental Stroke Model

Winters, A., Taylor, J. C., Ren, M., Ma, R., Liu, R. & Yang, S., 1 Jun 2012, In : Translational Stroke Research. 3, 2, p. 279-285 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Transient Ischemic Attack
Rodentia
Theoretical Models
Stroke
Phenylephrine
12 Citations (Scopus)

Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas

Wang, X., Zhang, H., Zhang, A., Han, L., Wang, K., Liu, R., Yang, S., Pu, P., Shen, C., Kang, C. & Yu, C., 1 Oct 2012, In : Oncology Reports. 28, 4, p. 1293-1300 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Glioma
Brain Stem
Up-Regulation
Pediatrics
MicroRNAs
2011
1 Citation (Scopus)

A globally convergent numerical method for coefficient inverse problems for thermal tomography

Pantong, N., Rhoden, A., Yang, S., Boetcher, S., Liu, H. & Su, J., 1 Oct 2011, In : Applicable Analysis. 90, 10, p. 1573-1594 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Tomography
Inverse problems
Tail
Numerical methods
Inverse Problem
131 Citations (Scopus)

Alternative mitochondrial electron transfer as a novel strategy for neuroprotection

Wen, Y., Li, W., Poteet, E. C., Xie, L., Tan, C., Yan, L-J., Ju, X., Liu, R., Qian, H., Marvin, M. A., Goldberg, M. S., She, H., Mao, Z., Simpkins, J. W. & Yang, S., 6 May 2011, In : Journal of Biological Chemistry. 286, 18, p. 16504-16515 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Methylene Blue
Electrons
Rotenone
Neuroprotection
Animal Disease Models
18 Citations (Scopus)

Estrogen protection in Friedreich's ataxia skin fibroblasts

Richardson, T. E., Yang, S., Wen, Y. & Simpkins, J. W., 1 Jul 2011, In : Endocrinology. 152, 7, p. 2742-2749 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Friedreich Ataxia
Estrogens
Fibroblasts
Skin
Oxidative Stress
35 Citations (Scopus)

Glutathione-conjugate transport by RLIP76 is required for clathrin-dependent endocytosis and chemical carcinogenesis

Singhal, S. S., Wickramarachchi, D., Yadav, S., Singhal, J., Leake, K., Vatsyayan, R., Chaudhary, P., Lelsani, P., Suzuki, S., Yang, S., Awasthi, Y. C. & Awasthi, S., 1 Jan 2011, In : Molecular Cancer Therapeutics. 10, 1, p. 16-28 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Clathrin
Endocytosis
Glutathione
Carcinogenesis
Neoplasms
53 Citations (Scopus)

Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone

Ding, Y., Winters, A., Ding, M., Graham, S., Akopova, I., Muallem, S., Wang, Y., Hong, J. H., Gryczynski, Z., Yang, S., Birnbaumer, L. & Ma, R., 9 Sep 2011, In : Journal of Biological Chemistry. 286, 36, p. 31799-31809 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Vasoconstrictor Agents
Vascular Smooth Muscle
Knockout Mice
Muscle Cells
Smooth Muscle Myocytes
28 Citations (Scopus)

Regulation of matrix metalloproteinase 2 by oligomeric amyloid β protein

Li, W., Poteet, E., Xie, L., Liu, R., Wen, Y. & Yang, S., 28 Apr 2011, In : Brain Research. 1387, p. 141-148 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Amyloidogenic Proteins
Matrix Metalloproteinase 2
Matrix Metalloproteinases
Astrocytes
Alzheimer Disease
21 Citations (Scopus)

The assessment of non-feminizing estrogens for use in neuroprotection

Yi, K. D., Perez, E., Yang, S., Liu, R., Covey, D. F. & Simpkins, J. W., 16 Mar 2011, In : Brain Research. 1379, p. 61-70 10 p.

Research output: Contribution to journalReview articleResearchpeer-review

Estrogens
Estrogen Receptor alpha
Steroids
Research
Women's Health
2010
36 Citations (Scopus)

Combination therapy of 17β-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke

Liu, R., Liu, Q., He, S., Simpkins, J. W. & Yang, S., 1 Mar 2010, In : Journal of Pharmacology and Experimental Therapeutics. 332, 3, p. 1006-1012 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Tissue Plasminogen Activator
Estradiol
Stroke
Middle Cerebral Artery Infarction
Transient Ischemic Attack
103 Citations (Scopus)

Mitochondrial mechanisms of estrogen neuroprotection

Simpkins, J. W., Yi, K. D., Yang, S. & Dykens, J. A., 1 Oct 2010, In : Biochimica et Biophysica Acta - General Subjects. 1800, 10, p. 1113-1120 8 p.

Research output: Contribution to journalReview articleResearchpeer-review

Mitochondria
Estrogens
Neurons
Neurodegenerative diseases
Oxidative stress
17 Citations (Scopus)

Modulation of polymorphonuclear neutrophil functions by astrocytes

Xie, L., Poteet, E. C., Li, W., Scott, A. E., Liu, R., Wen, Y., Ghorpade, A., Simpkins, J. W. & Yang, S., 9 Sep 2010, In : Journal of Neuroinflammation. 7, 53.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytes
Neutrophils
Phagocytosis
Respiratory Burst
Inbred C57BL Mouse