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  • Ignacy Gryczynski
2019

Fluorescence anisotropy imaging in drug discovery

Vinegoni, C., Feruglio, P. F., Gryczynski, I., Mazitschek, R. & Weissleder, R., 1 Nov 2019, In : Advanced Drug Delivery Reviews. 151-152, p. 262-288 27 p.

Research output: Contribution to journalReview article

11 Scopus citations

Non-fluorescent filters for fluorescence detection with in-line geometry

Kimball, J., Chavez, J., Ceresa, L., Shah, S., Gryczynski, I. & Gryczynski, Z., 16 May 2019, In : Methods and Applications in Fluorescence. 7, 3, 037001.

Research output: Contribution to journalArticle

Photophysical properties and detection of Valrubicin on plasmonic platforms

Synak, A., Szczepańska, E., Grobelna, B., Gondek, J., Mońka, M., Gryczynski, I. & Bojarski, P., Apr 2019, In : Dyes and Pigments. 163, p. 623-627 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Spectroscopic method for estimation of MMP-9 enzyme concentration and activity

Synak, A., Serdiuk, I. E., Grobelna, B., Fudala, R., Gryczynski, I. & Bojarski, P., 15 Jul 2019, In : Journal of Molecular Liquids. 286, 110936.

Research output: Contribution to journalArticle

2018

AMCA to TAMRA long range resonance energy transfer on a flexible peptide

Synak, A., Fudala, R., Gryczynski, I., Kułak, L., Shah, S., Serdiuk, I. E., Grobelna, B., Arłukowicz, P., Kubicki, A. & Bojarski, P., Nov 2018, In : Dyes and Pigments. 158, p. 60-64 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Differences in the spatial distribution of actin in the left and right ventricles of functioning rabbit hearts

Nagwekar, J., Duggal, D., Rich, R., Fudala, R., Gryczynski, I., Raut, S., Gryczynski, Z. & Borejdo, J., Mar 2018, In : Medical Photonics. 27, p. 1-8 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Enhanced DNA detection using a multiple pulse pumping scheme with time-gating (MPPTG)

Kimball, J. D., Maliwal, B., Raut, S. L., Doan, H., Nurekeyev, Z., Gryczynski, I. & Gryczynski, Z., 21 Jun 2018, In : Analyst. 143, 12, p. 2819-2827 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Enhanced emission of Nile Red on plasmonic platforms

Synak, A., Bojarski, P., Grobelna, B., Gryczyński, I., Fudala, R. & Mońka, M., Apr 2018, In : Optical Materials. 78, p. 82-87 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Optimization and scale up of microfluidic nanolipomer production method for preclinical and potential clinical trials

Gdowski, A., Johnson, K., Shah, S., Gryczynski, I., Vishwanatha, J. & Ranjan, A., 12 Feb 2018, In : Journal of Nanobiotechnology. 16, 1, 12.

Research output: Contribution to journalArticle

17 Scopus citations

Surface plasmon-assisted microscope

Borejdo, J., Gryczynski, Z., Fudala, R., Joshi, C. R., Borgmann, K., Ghorpade, A. & Gryczynski, I., 1 Jun 2018, In : Journal of Biomedical Optics. 23, 6, 060502.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Exosomal annexin II promotes angiogenesis and breast cancer metastasis

Maji, S., Chaudhary, P., Akopova, I., Nguyen, P. M., Hare, R. J., Gryczynski, I. & Vishwanatha, J. K., 1 Jan 2017, In : Molecular Cancer Research. 15, 1, p. 93-105 13 p.

Research output: Contribution to journalArticle

77 Scopus citations

Fluorescence properties of doxorubicin in PBS buffer and PVA films

Shah, S., Chandra, A., Kaur, A., Sabnis, N., Lacko, A., Gryczynski, Z., Fudala, R. & Gryczynski, I., 1 May 2017, In : Journal of Photochemistry and Photobiology B: Biology. 170, p. 65-69 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Imaging viscosity of intragranular mucin matrix in cystic fibrosis cells

Requena, S., Ponomarchuk, O., Castillo, M., Rebik, J., Brochiero, E., Borejdo, J., Gryczynski, I., Dzyuba, S. V., Gryczynski, Z., Grygorczyk, R. & Fudala, R., 1 Dec 2017, In : Scientific Reports. 7, 1, 16761.

Research output: Contribution to journalArticle

2 Scopus citations

Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging

Vinegoni, C., Feruglio, P. F., Brand, C., Lee, S., Nibbs, A. E., Stapleton, S., Shah, S., Gryczynski, I., Reiner, T., Mazitschek, R. & Weissleder, R., 1 Jul 2017, In : Nature Protocols. 12, 7, p. 1472-1497 26 p.

Research output: Contribution to journalArticle

7 Scopus citations

No difference in myosin kinetics and spatial distribution of the lever arm in the left and right ventricles of human hearts

Duggal, D., Requena, S., Nagwekar, J., Raut, S., Rich, R., Das, H., Patel, V., Gryczynski, I., Fudala, R., Gryczynski, Z., Blair, C., Campbell, K. S. & Borejdo, J., 13 Oct 2017, In : Frontiers in Physiology. 8, OCT, 732.

Research output: Contribution to journalArticle

Novel inorganic xerogels doped with CaWO4:xDy: Synthesis, characterization and luminescence properties

Grobelna, B., Synak, A., Głowaty, D., Bojarski, P., Szczepańska, E., Szczodrowski, K., Gryczynski, I. & Karczewski, J., 15 Sep 2017, In : Materials Chemistry and Physics. 199, p. 166-172 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Solvatochromic dye LDS 798 as microviscosity and pH probe

Doan, H., Castillo, M., Bejjani, M., Nurekeyev, Z., Dzyuba, S. V., Gryczynski, I., Gryczynski, Z. & Raut, S., 1 Jan 2017, In : Physical Chemistry Chemical Physics. 19, 44, p. 29934-29939 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Spectral features and excited-state transformations of hydroxy derivatives of 4'N,N-dimethylaminoflavone in PVA films and on plasmonic platforms

Serdiuk, I. E., Synak, A., Grobelna, B., Gryczynski, I. & Bojarski, P., 1 Jan 2017, In : Journal of Physical Chemistry C. 121, 1, p. 636-648 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Spectroscopic Properties and Conformational Analysis of Methyl Ester of Sinapic Acid in Various Environments

Smyk, B., Mȩdza, G., Kasparek, A., Pyrka, M., Gryczynski, I. & Maciejczyk, M., 3 Aug 2017, In : Journal of Physical Chemistry B. 121, 30, p. 7299-7310 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Tryptophan Fluorescence Yields and Lifetimes as a Probe of Conformational Changes in Human Glucokinase

Zelent, B., Bialas, C., Gryczynski, I., Chen, P., Chib, R., Lewerissa, K., Corradini, M. G., Ludescher, R. D., Vanderkooi, J. M. & Matschinsky, F. M., 1 Sep 2017, In : Journal of Fluorescence. 27, 5, p. 1621-1631 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

A triazine-based BODIPY trimer as a molecular viscometer

Raut, S. L., Kimball, J. D., Fudala, R., Bora, I., Chib, R., Jaafari, H., Castillo, M. K., Smith, N. W., Gryczynski, I., Dzyuba, S. V. & Gryczynski, Z., 2016, In : Physical Chemistry Chemical Physics. 18, 6, p. 4535-4540 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Defect-mediated spontaneous emission enhancement of plasmon-coupled CuInS2 and CuInS2/ZnS

Rice, Q., Raut, S., Chib, R., Hayes, A., Gryczynski, Z., Gryczynski, I., Kim, Y. K., Tabibi, B. & Seo, J., 1 Jan 2016, In : Optical Materials Express. 6, 2, p. 566-577 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Demonstration of FRET in solutions

Shah, S., Gryczynski, Z., Chib, R., Fudala, R., Baxi, A., Borejdo, J., Synak, A. & Gryczynski, I., Mar 2016, In : Methods and Applications in Fluorescence. 4, 1, 015001.

Research output: Contribution to journalArticle

2 Scopus citations

Excitation energy transfer in partly ordered polymer films differing in donor and acceptor transition moments orientation

Synak, A., Bojarski, P., Sadownik, M., Kułak, L., Gryczynski, I., Grobelna, B., Rangełowa-Jankowska, S., Jankowski, D. & Kubicki, A., 1 Sep 2016, In : Optical Materials. 59, p. 34-38 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
6 Scopus citations

FRET study in oligopeptide-linked donor-acceptor system in PVA matrix

Shah, S., Mandecki, W., Li, J., Gryczynski, Z., Borejdo, J., Gryczynski, I. & Fudala, R., 13 Dec 2016, In : Methods and Applications in Fluorescence. 4, 4, 1 p.

Research output: Contribution to journalArticle

Identifying and selecting edible luminescent probes as sensors of food quality

Corradini, M. G., Wang, Y. L., Le, A., Waxman, S. M., Zelent, B., Chib, R., Gryczynski, I. & Ludescher, R. D., 1 Jan 2016, In : AIMS Biophysics. 3, 2, p. 319-339 21 p.

Research output: Contribution to journalReview article

5 Scopus citations

Linear dichroism and optical anisotropy of silver nanoprisms in polymer films

Requena, S., Doan, H., Raut, S. L., D'Achille, A., Gryczynski, Z., Gryczynski, I. & Strzhemechny, Y. M., 27 Jun 2016, In : Nanotechnology. 27, 32, 325704.

Research output: Contribution to journalArticle

2 Scopus citations

Luminescent properties of Ln3+ doped tellurite glasses containing AlF3

Walas, M., Pastwa, A., Lewandowski, T., Synak, A., Gryczyński, I., Sadowski, W. & Kościelska, B., 1 Sep 2016, In : Optical Materials. 59, p. 70-75 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

Metal enhanced fluorescence of flavin mononucleotide using new plasmonic platform

Synak, A., Grobelna, B., Raut, S., Bojarski, P., Gryczyński, I., Karczewski, J. & Shtoyko, T., 1 Sep 2016, In : Optical Materials. 59, p. 136-140 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Multi-pulse pumping for far-field super-resolution imaging

Requena, S., Raut, S., Doan, H., Kimball, J., Fudala, R., Borejdo, J., Gryczynski, I., Strzhemechny, Y. & Gryczynski, Z., 1 Jan 2016, Single Molecule Spectroscopy and Superresolution Imaging IX. Enderlein, J., Gregor, I., Gryczynski, Z. K., Erdmann, R. & Koberling, F. (eds.). SPIE, 97140F. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9714).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Novel plasmonic platform for ultra-sensitive detection and diagnostics

Raut, S. L., Rich, R., Shtoyko, T., Requena, S., Bora, I., Laursen, B. W., Sørensen, T. J., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 1 Jan 2016, Single Molecule Spectroscopy and Superresolution Imaging IX. Enderlein, J., Gregor, I., Gryczynski, Z. K., Erdmann, R. & Koberling, F. (eds.). SPIE, Vol. 9714. 971419

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Photophysical characterization of anticancer drug valrubicin in rHDL nanoparticles and its use as an imaging agent

Shah, S., Chib, R., Raut, S., Bermudez, J., Sabnis, N., Duggal, D., Kimball, J. D., Lacko, A. G., Gryczynski, Z. & Gryczynski, I., Feb 2016, In : Journal of Photochemistry and Photobiology B: Biology. 155, p. 60-65 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
2015

A Novel Method of Determining the Functional Effects of a Minor Genetic Modification of a Protein

Nagwekar, J., Duggal, D., Midde, K., Rich, R., Liang, J., Kazmierczak, K., Huang, W., Fudala, R., Gryczynski, I., Gryczynski, Z., Szczesna-Cordary, D. & Borejdo, J., 18 Nov 2015, In : Frontiers in Cardiovascular Medicine. 2, 35.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effect of a myosin regulatory light chain mutation K104E on actin-myosin interactions

Duggal, D., Nagwekar, J., Rich, R., Huang, W., Midde, K., Fudala, R., Das, H., Gryczynski, I., Szczesna-Cordary, D. & Borejdo, J., 15 May 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 10, p. H1248-H1257

Research output: Contribution to journalArticle

4 Scopus citations

Effect of quencher, denaturants, temperature and pH on the fluorescent properties of BSA protected gold nanoclusters

Chib, R., Butler, S., Raut, S., Shah, S., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 17 Aug 2015, In : Journal of Luminescence. 168, p. 62-68 7 p., LUMIND1500227.

Research output: Contribution to journalArticle

15 Scopus citations

Sandwich type plasmonic platform for MEF using silver fractals

Raut, S. L., Rich, R., Shtoyko, T., Bora, I., Laursen, B. W., Sørensen, T. J., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 14 Nov 2015, In : Nanoscale. 7, 42, p. 17729-17734 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Standard reference for instrument response function in fluorescence lifetime measurements in visible and near infrared

Chib, R., Shah, S., Gryczynski, Z., Fudala, R., Borejdo, J., Zelent, B., Corradini, M. G., Ludescher, R. D. & Gryczynski, I., 29 Dec 2015, In : Measurement Science and Technology. 27, 2, 027001.

Research output: Contribution to journalArticle

2 Scopus citations

Steady state and time resolved fluorescence studies of azadioxatriangulenium (ADOTA) fluorophore in silica and PVA thin films

Chib, R., Raut, S., Shah, S., Grobelna, B., Akopova, I., Rich, R., Sørensen, T. J., Laursen, B. W., Grajek, H., Gryczynski, Z. & Gryczynski, I., Jun 2015, In : Dyes and Pigments. 117, p. 16-23 8 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

A homodimeric BODIPY rotor as a fluorescent viscosity sensor for membrane-mimicking and cellular environments

Raut, S., Kimball, J., Fudala, R., Doan, H., Maliwal, B., Sabnis, N., Lacko, A., Gryczynski, I., Dzyuba, S. V. & Gryczynski, Z., 19 Nov 2014, In : Physical Chemistry Chemical Physics. 16, 48, p. 27037-27042 6 p.

Research output: Contribution to journalArticle

43 Scopus citations

Associated anisotropy decays of Ethidium Bromide interacting with DNA

Chib, R., Raut, S. L., Sabnis, S., Singhal, P., Gryczynski, Z. & Gryczynski, I., 1 Mar 2014, In : Methods and Applications in Fluorescence. 2, 1, 015003.

Research output: Contribution to journalArticle

9 Scopus citations

BSA AU clusters as a probe for enhanced fluorescence detection using multipulse excitation scheme

Raut, S. L., Rich, R., Fudala, R., Kokate, R., Kimball, J. D., Borejdo, J., Vishwanatha, J. K., Gryczynski, Z. & Gryczynski, I., 1 Jan 2014, In : Current Pharmaceutical Biotechnology. 14, 13, p. 1139-1144 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evidence of energy transfer from tryptophan to BSA/HSA protected gold nanoclusters

Raut, S., Chib, R., Butler, S., Borejdo, J., Gryczynski, Z. & Gryczynski, I., Sep 2014, In : Methods and Applications in Fluorescence. 2, 3, 035004.

Research output: Contribution to journalArticle

23 Scopus citations

Fluorescence detection of MMP-9. II. ratiometric FRET-based sensing with dually labeled specific peptide

Fudala, R., Rich, R., Mukerjee, A., Ranjan, A. P., Vishwanatha, J. K., Kurdowska, A. K., Gryczynski, Z., Borejdo, J. & Gryczynski, I., 1 Jan 2014, In : Current Pharmaceutical Biotechnology. 14, 13, p. 1134-1138 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Fluorescent nanodiamonds for ultrasensitive detection

Kimball, J., Shumilov, D., Maliwa, B., Zerda, T. W., Rout, B., Fudala, R., Raut, S. L., Gryczynski, I., Simanek, E., Borejdo, J., Rich, R., Akopova, I. & Gryczynski, Z., 1 Jan 2014, Single Molecule Spectroscopy and Superresolution Imaging VII. SPIE, 89501H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8950).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fractional contributions of defect-originated photoluminescence from CuInS2/ZnS coreshells for hybrid white LEDs

Rice, Q., Raut, S., Chib, R., Gryczynski, Z., Gryczynski, I., Zhang, W., Zhong, X., Abdel-Fattah, M., Tabibi, B. & Seo, J., 2014, In : Journal of Nanomaterials. 2014, 979875.

Research output: Contribution to journalArticle

2 Scopus citations

FRET enhanced fluorescent nanodiamonds

Fudala, R., Raut, S., Maliwal, B. P., Zerda, T. W., Gryczynski, I., Simanek, E., Borejdo, J., Rich, R., Akopova, I. & Gryczynski, Z., 1 Jan 2014, In : Current Pharmaceutical Biotechnology. 14, 13, p. 1127-1133 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Generating multiple-pulse bursts for enhanced fluorescence detection

Shumilov, D., Rich, R. M., Gryczynski, I., Raut, S., Gryczynski, K., Kimball, J., Doan, H., Soørensen, T. J., Laursen, B. W., Borejdo, J. & Gryczynski, Z., Jun 2014, In : Methods and Applications in Fluorescence. 2, 2, 024009.

Research output: Contribution to journalArticle

4 Scopus citations

Long lived BSA Au clusters as a time gated intensity imaging probe

Raut, S. L., Fudala, R., Rich, R., Kokate, R. A., Chib, R., Gryczynski, Z. & Gryczynski, I., 7 Mar 2014, In : Nanoscale. 6, 5, p. 2594-2597 4 p.

Research output: Contribution to journalArticle

24 Scopus citations