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2019

[ 99 mTc-HYNIC-N-dodecylamide]:a new hydrophobic tracer for labelling reconstituted high-density lipoproteins (rHDL) for radioimaging

Isaac-Olivé, K., Ocampo-García, B. E., Aranda-Lara, L., Santos-Cuevas, C. L., Jiménez-Mancilla, N. P., Luna-Gutiérrez, M. A., Medina, L. A., Nagarajan, B., Sabnis, N., Raut, S. L., Prokai, L. & Lacko, A. G., 14 Jan 2019, In : Nanoscale. 11, 2, p. 541-551 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipoproteins
HDL Lipoproteins
Labeling
Imaging techniques
Acids

Identifying and targeting angiogenesis-related microRNAs in ovarian cancer

Chen, X., Mangala, L. S., Mooberry, L., Bayraktar, E., Dasari, S. K., Ma, S., Ivan, C., Court, K. A., Rodriguez-Aguayo, C., Bayraktar, R., Raut, S. L., Sabnis, N., Kong, X., Yang, X., Lopez-Berestein, G., Lacko, A. G. & Sood, A. K., 15 Aug 2019, In : Oncogene. 38, 33, p. 6095-6108 14 p.

Research output: Contribution to journalArticleResearchpeer-review

MicroRNAs
Ovarian Neoplasms
Neoplasms
CD36 Antigens
Vascular Endothelial Growth Factor A

The SR-B1 Receptor as a Potential Target for Treating Glioblastoma

Berney, E., Sabnis, N., Panchoo, M., Raut, S. L., Dickerman, R. & Lacko, A. G., 1 Jan 2019, In : Journal of Oncology. 2019, 1805841.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Scavenger Receptors
Glioblastoma
HDL Lipoproteins
Cell Cycle
Sirolimus
2018
2 Citations (Scopus)

Lipoproteins for therapeutic delivery: Recent advances and future opportunities

Raut, S. L., Dasseux, J. L., Sabnis, N. A., Mooberry, L. & Lacko, A. G., 1 Jan 2018, In : Therapeutic Delivery. 9, 4, p. 257-268 12 p.

Research output: Contribution to journalReview articleResearchpeer-review

Lipoproteins
Neoplasms
Triglycerides
Therapeutics
Cholesterol
3 Citations (Scopus)

Reconstituted HDL: Drug delivery platform for overcoming biological barriers to cancer therapy

Raut, S. L., Mooberry, L., Sabnis, N., Garud, A., Dossou, A. S. & Lacko, A. G., 15 Oct 2018, In : Frontiers in Pharmacology. 9, OCT, 01154.

Research output: Contribution to journalReview articleResearchpeer-review

Pharmaceutical Preparations
Neoplasms
Nanoparticles
Therapeutics
Technology
5 Citations (Scopus)

Scavenger receptor class B type 1 regulates neuroblastoma cell proliferation, migration and invasion

Panchoo, M. & Lacko, A. G., 1 Jan 2018, In : Biochemical and Biophysical Research Communications. 495, 1, p. 614-620 7 p.

Research output: Contribution to journalArticleResearchpeer-review

CD36 Antigens
Cell proliferation
Neuroblastoma
Cell Movement
Cell Proliferation
2017
5 Citations (Scopus)

Fluorescence properties of doxorubicin in PBS buffer and PVA films

Shah, S., Chandra, A., Kaur, A., Sabnis, N., Lacko, A. G., Gryczynski, Z., Fudala, R. & Gryczynski, I., 1 May 2017, In : Journal of Photochemistry and Photobiology B: Biology. 170, p. 65-69 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Doxorubicin
Buffers
alcohols
buffers
Fluorescence
5 Citations (Scopus)

SR-B1-targeted nanodelivery of anti-cancer agents: A promising new approach to treat triplenegative breast cancer

Johnson, R., Sabnis, N., Sun, X. L., Ahluwalia, R. & Lacko, A. G., 2 Jun 2017, In : Breast Cancer: Targets and Therapy. 9, p. 383-392 10 p.

Research output: Contribution to journalArticleResearchpeer-review

CD36 Antigens
Triple Negative Breast Neoplasms
HDL Lipoproteins
Breast Neoplasms
Nanoparticles
9 Citations (Scopus)

Superparamagnetic reconstituted high-density lipoprotein nanocarriers for magnetically guided drug delivery

Sabnis, S., Sabnis, N. A., Raut, S. L. & Lacko, A. G., 22 Feb 2017, In : International Journal of Nanomedicine. 12, p. 1453-1464 12 p.

Research output: Contribution to journalArticleResearchpeer-review

valrubicin
Lipoproteins
HDL Lipoproteins
Drug delivery
Nanoparticles
1 Citation (Scopus)

Ultrasound-stimulated drug delivery of reconstituted high density lipoprotein nanoparticles: Effects of drug concentration on tumor uptake

Xiong, F., Xiong, M., Nirupama, S., Sirsi, S., Lacko, A. G. & Hoyt, K., 31 Oct 2017, 2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 8092380

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

lipoproteins
delivery
drugs
tumors
nanoparticles

Ultrasound-stimulated drug delivery of reconstituted high-density lipoprotein nanoparticles: Effects of drug concentration on tumor uptake

Xiong, F., Nirupama, S., Sirsi, S. R., Lacko, A. G. & Hoyt, K., 31 Oct 2017, 2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 8092663

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

lipoproteins
delivery
drugs
tumors
nanoparticles
2016
8 Citations (Scopus)

Photophysical characterization of anticancer drug valrubicin in rHDL nanoparticles and its use as an imaging agent

Shah, S., Chib, R., Raut, S. L., Bermudez, J., Sabnis, N., Duggal, D., Kimball, J. D., Lacko, A. G., Gryczynski, Z. & Gryczynski, I., 1 Feb 2016, In : Journal of Photochemistry and Photobiology B: Biology. 155, p. 60-65 6 p.

Research output: Contribution to journalArticleResearchpeer-review

valrubicin
lipoproteins
HDL Lipoproteins
Nanoparticles
drugs
23 Citations (Scopus)

Targeting the SR-B1 receptor as a gateway for cancer therapy and imaging

Mooberry, L. K., Sabnis, N. A., Panchoo, M., Nagarajan, B. & Lacko, A. G., 1 Jan 2016, In : Frontiers in Pharmacology. 7, DEC, 466.

Research output: Contribution to journalReview articleResearchpeer-review

Scavenger Receptors
CD36 Antigens
Neoplasms
Therapeutics
Cholesterol Esters
2015
21 Citations (Scopus)

HDL as a drug and nucleic acid delivery vehicle

Lacko, A. G., Sabnis, N. A., Nagarajan, B. & McConathy, W. J., 1 Jan 2015, In : Frontiers in Pharmacology. 6, OCT, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Nucleic Acids
Pharmaceutical Preparations
Nanoparticles
Cholesterol Esters
2014
33 Citations (Scopus)

A homodimeric BODIPY rotor as a fluorescent viscosity sensor for membrane-mimicking and cellular environments

Raut, S. L., Kimball, J., Fudala, R., Doan, H., Maliwal, B., Sabnis, N., Lacko, A. G., Gryczynski, I., Dzyuba, S. V. & Gryczynski, Z., 19 Nov 2014, In : Physical Chemistry Chemical Physics. 16, 48, p. 27037-27042 6 p.

Research output: Contribution to journalArticleResearchpeer-review

rotors
Rotors
Fluorescence
Viscosity
viscosity
10 Citations (Scopus)

Targeted nanoparticles for pediatric leukemia therapy

Basha, R. M., Sabnis, N., Heym, K., Bowman, P. & Lacko, A. G., 1 Jan 2014, In : Frontiers in Oncology. 4 MAY, 101.

Research output: Contribution to journalReview articleResearchpeer-review

Nanoparticles
Leukemia
Pediatrics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
2013
26 Citations (Scopus)

Pre-clinical evaluation of rHDL encapsulated retinoids for the treatment of neuroblastoma

Sabnis, N., Pratap, S., Akopova, I., Bowman, P. & Lacko, A. G., 1 Mar 2013, In : Frontiers in Pediatrics. 1, MAR, 6.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Fenretinide
Retinoids
HDL Lipoproteins
Neuroblastoma
Nanoparticles
10 Citations (Scopus)

The potential role of nanotechnology in therapeutic approaches for triple negative breast cancer

Johnson, R., Sabnis, N., McConathy, W. J. & Lacko, A. G., 18 Jun 2013, In : Pharmaceutics. 5, 2, p. 353-370 18 p.

Research output: Contribution to journalReview articleResearchpeer-review

Triple Negative Breast Neoplasms
Nanotechnology
Breast Neoplasms
Survival Rate
Therapeutics
106 Citations (Scopus)

The role of cholesterol metabolism and cholesterol transport in carcinogenesis: A review of scientific findings, relevant to future cancer therapeutics

Cruz, P. M. R., Mo, H., McConathy, W. J., Sabnis, N. & Lacko, A. G., 16 Oct 2013, In : Frontiers in Pharmacology. 4 SEP, Article 119.

Research output: Contribution to journalReview articleResearchpeer-review

Carcinogenesis
Cholesterol
Neoplasms
Therapeutics
Bile Acids and Salts
2012
31 Citations (Scopus)

Drug delivery via lipoprotein-based carriers: Answering the challenges in systemic therapeutics

Sabnis, N. & Lacko, A. G., 1 May 2012, In : Therapeutic Delivery. 3, 5, p. 599-608 10 p.

Research output: Contribution to journalReview articleResearchpeer-review

Lipoproteins
Pharmaceutical Preparations
Therapeutics
Neoplasms
Drug Carriers
33 Citations (Scopus)

Enhanced solubility and functionality of valrubicin (AD-32) against cancer cells upon encapsulation into biocompatible nanoparticles

Sabnis, N., Nair, M. P., Israel, M., McConathy, W. J. & Lacko, A. G., 5 Dec 2012, In : International Journal of Nanomedicine. 7, p. 975-983 9 p.

Research output: Contribution to journalArticleResearchpeer-review

valrubicin
Lipoproteins
Encapsulation
Nanoparticles
Solubility
Lipoproteins
Pharmaceutical Preparations
Therapeutics
2011
128 Citations (Scopus)

Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles

Shahzad, M. M. K., Mangala, L. S., Han, H. D., Lu, C., Bottsford-Miller, J., Nishimura, M., Mora, E. M., Lee, J. W., Stone, R. L., Pecot, C. V., Thanapprapasr, D., Roh, J. W., Gaur, P., Nair, M. P., Park, Y. Y., Sabnis, N., Deavers, M. T., Lee, J. S., Ellis, L. M., Lopez-Berestei, G. & 4 others, McConathy, W. J., Prokai, L., Lacko, A. G. & Sood, A. K., 1 Jan 2011, In : Neoplasia. 13, 4, p. 309-319 11 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Nanoparticles
Small Interfering RNA
Scavenger Receptors
Neoplasms
10 Citations (Scopus)

Validation of the reconstituted high-density lipoprotein (rHDL) drug delivery platform using dilauryl fluorescein (DLF)

McConathy, W. J., Paranjape, S., Mooberry, L., Buttreddy, S., Nair, M. P. & Lacko, A. G., 1 Apr 2011, In : Drug Delivery and Translational Research. 1, 2, p. 113-120 8 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Fluorescein
Pharmaceutical Preparations
Hydrolysis
lauric acid
2010
81 Citations (Scopus)

Receptor mediated uptake of paclitaxel from a synthetic high density lipoprotein nanocarrier

Mooberry, L. K., Nair, M. P., Paranjape, S., McConathy, W. J. & Lacko, A. G., 1 Jan 2010, In : Journal of Drug Targeting. 18, 1, p. 53-58 6 p.

Research output: Contribution to journalArticleResearchpeer-review

HDL Lipoproteins
Paclitaxel
Scavenger Receptors
Nanoparticles
Pharmaceutical Preparations
6 Citations (Scopus)

Studies on solvatochromic properties of aminophenylstyryl-quinolinum dye, LDS 798, and its application in studying submicron lipid based structure

Sarkar, P., Luchowski, R., Raut, S. L., Sabnis, N., Remaley, A., Lacko, A. G., Thamake, S., Gryczynski, Z. & Gryczynski, I., 1 Dec 2010, In : Biophysical Chemistry. 153, 1, p. 61-69 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Coloring Agents
Lipids
Unilamellar Liposomes
Fluorescence Spectrometry
Nanoparticles