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2018
1 Citation (Scopus)

Differences in the spatial distribution of actin in the left and right ventricles of functioning rabbit hearts

Nagwekar, J., Duggal, D., Rich, R., Fudala, R., Gryczynski, I., Raut, S. L., Gryczynski, Z. & Borejdo, J., 1 Mar 2018, In : Medical Photonics. 27, p. 1-8 8 p.

Research output: Contribution to journalArticle

Heart Ventricles
Actins
Myosins
Rabbits
Muscles

Surface plasmon-assisted microscope

Borejdo, J., Gryczynski, Z., Fudala, R., Joshi, C. R., Borgmann, K., Ghorpade, A. & Gryczynski, I., 1 Jun 2018, In : Journal of Biomedical Optics. 23, 6, 060502.

Research output: Contribution to journalArticle

Microscopes
microscopes
membranes
metal surfaces
Metals
2017
2 Citations (Scopus)

Imaging viscosity of intragranular mucin matrix in cystic fibrosis cells

Requena, S., Ponomarchuk, O., Castillo, M., Rebik, J., Brochiero, E., Borejdo, J., Gryczynski, I., Dzyuba, S. V., Gryczynski, Z., Grygorczyk, R. & Fudala, R., 1 Dec 2017, In : Scientific Reports. 7, 1, 16761.

Research output: Contribution to journalArticle

Mucins
Cystic Fibrosis
Viscosity
Optical Imaging
Mucus

No difference in myosin kinetics and spatial distribution of the lever arm in the left and right ventricles of human hearts

Duggal, D., Requena, S., Nagwekar, J., Raut, S., Rich, R., Das, H., Patel, V., Gryczynski, I., Fudala, R., Gryczynski, Z., Blair, C., Campbell, K. S. & Borejdo, J., 13 Oct 2017, In : Frontiers in Physiology. 8, OCT, 732.

Research output: Contribution to journalArticle

Myosins
Heart Ventricles
Muscle Cells
Ventricular Myosins
Muscle Proteins
2016
2 Citations (Scopus)

Demonstration of FRET in solutions

Shah, S., Gryczynski, Z., Chib, R., Fudala, R., Baxi, A., Borejdo, J., Synak, A. & Gryczynski, I., Mar 2016, In : Methods and Applications in Fluorescence. 4, 1, 015001.

Research output: Contribution to journalArticle

Rhodamines
rhodamine
Energy transfer
Demonstrations
Fluorescence
1 Citation (Scopus)
Hyaluronoglucosaminidase
Fluorophores
Fluorescence
Imaging techniques
Hyaluronic acid
6 Citations (Scopus)
Hyaluronoglucosaminidase
Fluorophores
Biosensing Techniques
Biosensors
Fluorescence

FRET study in oligopeptide-linked donor-acceptor system in PVA matrix

Shah, S., Mandecki, W., Li, J., Gryczynski, Z., Borejdo, J., Gryczynski, I. & Fudala, R., 13 Dec 2016, In : Methods and applications in fluorescence. 4, 4, 1 p.

Research output: Contribution to journalArticle

Oligopeptides
resonance fluorescence
lysine
energy transfer
Lysine

Multi-pulse pumping for far-field super-resolution imaging

Requena, S., Raut, S. L., Doan, H., Kimball, J., Fudala, R., Borejdo, J., Gryczynski, I., Strzhemechny, Y. & Gryczynski, Z., 1 Jan 2016, Single Molecule Spectroscopy and Superresolution Imaging IX. SPIE, Vol. 9714. 97140F

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical Imaging
far fields
pumping
Coloring Agents
Imaging techniques

Novel plasmonic platform for ultra-sensitive detection and diagnostics

Raut, S. L., Rich, R., Shtoyko, T., Requena, S., Bora, I., Laursen, B. W., Sørensen, T. J., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 1 Jan 2016, Single Molecule Spectroscopy and Superresolution Imaging IX. Enderlein, J., Gregor, I., Gryczynski, Z. K., Erdmann, R. & Koberling, F. (eds.). SPIE, Vol. 9714. 971419

Research output: Chapter in Book/Report/Conference proceedingConference contribution

platforms
Fluorescence
Fractals
fluorescence
Glass
2015
4 Citations (Scopus)

Effect of a myosin regulatory light chain mutation K104E on actin-myosin interactions

Duggal, D., Nagwekar, J., Rich, R., Huang, W., Midde, K., Fudala, R., Das, H., Gryczynski, I., Szczesna-Cordary, D. & Borejdo, J., 15 May 2015, In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 10, p. H1248-H1257

Research output: Contribution to journalArticle

Myosin Light Chains
Myosins
Familial Hypertrophic Cardiomyopathy
Actins
Mutation
11 Citations (Scopus)

Effect of quencher, denaturants, temperature and pH on the fluorescent properties of BSA protected gold nanoclusters

Chib, R., Butler, S., Raut, S., Shah, S., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 17 Aug 2015, In : Journal of Luminescence. 168, p. 62-68 7 p., LUMIND1500227.

Research output: Contribution to journalArticle

Nanoclusters
nanoclusters
Tryptophan
Gold
tryptophan
5 Citations (Scopus)

Sandwich type plasmonic platform for MEF using silver fractals

Raut, S. L., Rich, R., Shtoyko, T., Bora, I., Laursen, B. W., Sørensen, T. J., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 14 Nov 2015, In : Nanoscale. 7, 42, p. 17729-17734 6 p.

Research output: Contribution to journalArticle

Silver
Fractals
Metals
Fluorescence
Coloring Agents
2 Citations (Scopus)

Standard reference for instrument response function in fluorescence lifetime measurements in visible and near infrared

Chib, R., Shah, S., Gryczynski, Z., Fudala, R., Borejdo, J., Zelent, B., Corradini, M. G., Ludescher, R. D. & Gryczynski, I., 29 Dec 2015, In : Measurement Science and Technology. 27, 2, 027001.

Research output: Contribution to journalArticle

Fluorescence Lifetime
Response Function
Infrared
Fluorescence
Infrared radiation
2014
1 Citation (Scopus)

BSA AU clusters as a probe for enhanced fluorescence detection using multipulse excitation scheme

Raut, S. L., Rich, R., Fudala, R., Kokate, R., Kimball, J. D., Borejdo, J., Vishwanatha, J. K., Gryczynski, Z. & Gryczynski, I., 1 Jan 2014, In : Current Pharmaceutical Biotechnology. 14, 13, p. 1139-1144 6 p.

Research output: Contribution to journalArticle

Fluorescence
Optical Imaging
Noise
13 Citations (Scopus)

Cell surface translocation of annexin A2 facilitates Glutamate-induced extracellular proteolysis

Valapala, M., Maji, S., Borejdo, J. & Vishwanatha, J. K., 6 Jun 2014, In : Journal of Biological Chemistry. 289, 23, p. 15915-15926 12 p.

Research output: Contribution to journalArticle

Annexin A2
Proteolysis
Glutamic Acid
Fibrinolysin
Plasminogen
20 Citations (Scopus)

Evidence of energy transfer from tryptophan to BSA/HSA protected gold nanoclusters

Raut, S. L., Chib, R., Butler, S., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 1 Sep 2014, In : Methods and Applications in Fluorescence. 2, 3, 035004.

Research output: Contribution to journalArticle

Nanoclusters
tryptophan
nanoclusters
Tryptophan
Gold
10 Citations (Scopus)

Fluorescence detection of MMP-9. II. ratiometric FRET-based sensing with dually labeled specific peptide

Fudala, R., Rich, R., Mukerjee, A., Ranjan, A. P., Vishwanatha, J. K., Kurdowska, A. K., Gryczynski, Z., Borejdo, J. & Gryczynski, I., 1 Jan 2014, In : Current Pharmaceutical Biotechnology. 14, 13, p. 1134-1138 5 p.

Research output: Contribution to journalArticle

Energy Transfer
Matrix Metalloproteinases
Fluorescence
Peptides
Enzymes

Fluorescent nanodiamonds for ultrasensitive detection

Kimball, J., Shumilov, D., Maliwa, B., Zerda, T. W., Rout, B., Fudala, R., Raut, S. L., Gryczynski, I., Simanek, E., Borejdo, J., Rich, R., Akopova, I. & Gryczynski, Z., 1 Jan 2014, Single Molecule Spectroscopy and Superresolution Imaging VII. SPIE, 89501H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8950).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanodiamonds
Fluorescence
fluorescence
platforms
Detectors
10 Citations (Scopus)

FRET enhanced fluorescent nanodiamonds

Fudala, R., Raut, S. L., Maliwal, B. P., Zerda, T. W., Gryczynski, I., Simanek, E., Borejdo, J., Rich, R., Akopova, I. & Gryczynski, Z., 1 Jan 2014, In : Current Pharmaceutical Biotechnology. 14, 13, p. 1127-1133 7 p.

Research output: Contribution to journalArticle

Nanodiamonds
Fluorescence Resonance Energy Transfer
Coloring Agents
Fluorescence
Dendrimers
3 Citations (Scopus)

Generating multiple-pulse bursts for enhanced fluorescence detection

Shumilov, D., Rich, R. M., Gryczynski, I., Raut, S., Gryczynski, K., Kimball, J., Doan, H., Soørensen, T. J., Laursen, B. W., Borejdo, J. & Gryczynski, Z., Jun 2014, In : Methods and Applications in Fluorescence. 2, 2, 024009.

Research output: Contribution to journalArticle

bursts
Fluorescence
fluorescence
repetition
probes
17 Citations (Scopus)

Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice

Huang, W., Liang, J., Kazmierczak, K., Muthu, P., Duggal, D., Farman, G. P., Sorensen, L., Pozios, I., Abraham, T. P., Moore, J. R., Borejdo, J. & Szczesna-Cordary, D., 1 Jan 2014, In : Journal of Molecular and Cellular Cardiology. 74, p. 318-329 12 p.

Research output: Contribution to journalArticle

Myosin Light Chains
Hypertrophic Cardiomyopathy
Myosins
Mutation
Muscle Relaxation
5 Citations (Scopus)
Presenilin-1
Fluorescence Spectrometry
Energy Transfer
Energy transfer
Fluorescence
10 Citations (Scopus)

Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in tissue

Rich, R. M., Gryczynski, I., Fudala, R., Borejdo, J., Stankowska, D. L., Krishnamoorthy, R., Raut, S. L., Maliwal, B. P., Shumilov, D., Doan, H. & Gryczynski, Z., 15 Mar 2014, In : Methods. 66, 2, p. 292-298 7 p.

Research output: Contribution to journalArticle

Molecular imaging
Molecular Imaging
Optical Imaging
Ruthenium
Fluorescence
4 Citations (Scopus)
Myosin Light Chains
Myosins
Skeletal Muscle
Phosphorylation
Rabbits

Rapid Measurements of Orientation and Rotation in Ex Vivo Muscle Made Possible by Studying Small Number of Cross-Bridges

Borejdo, J., 18 Mar 2014, Fluorescence Microscopy: Super-Resolution and other Novel Techniques. Elsevier Inc., p. 35-48 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Muscle
Myosins
Muscles
Actins
Neck
5 Citations (Scopus)

Real-time imaging of exocytotic mucin release and swelling in Calu-3 cells using acridine orange

Shumilov, D., Popov, A., Fudala, R., Akopova, I., Gryczynski, I., Borejdo, J., Gryczynski, Z. & Grygorczyk, R., 15 Mar 2014, In : Methods. 66, 2, p. 312-324 13 p.

Research output: Contribution to journalArticle

Acridine Orange
Mucins
Swelling
Fluorescence
Imaging techniques

Simple multipulse excitation for enhanced detection of long-lived fluorophores

Kimball, J., Shumilov, D., Fudala, R., Raut, S. L., Gryczynski, I., Borejdo, J., Akopova, I., Grygorczyk, R. & Gryczynski, Z., 1 Jan 2014, Single Molecule Spectroscopy and Superresolution Imaging VII. SPIE, Vol. 8950. 895005

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Fluorophores
life (durability)
excitation
Lasers
repetition
1 Citation (Scopus)

The spatial distribution of actin and mechanical cycle of myosin are different in right and left ventricles of healthy mouse hearts

Nagwekar, J., Duggal, D., Rich, R., Raut, S., Fudala, R., Gryczynski, I., Gryczynski, Z. & Borejdo, J., 9 Dec 2014, In : Biochemistry. 53, 48, p. 7641-7649 9 p.

Research output: Contribution to journalArticle

Myosins
Spatial distribution
Heart Ventricles
Actins
Blood
2013
17 Citations (Scopus)

Comparison of orientation and rotational motion of skeletal muscle cross-bridges containing phosphorylated and dephosphorylated myosin regulatory light chain

Midde, K., Ryan Rich, R., Peter Marandos, M., Rafal Fudala, F., Amy Li, L., Ignacy Gryczynski, G. & Borejdo, J., 8 Mar 2013, In : Journal of Biological Chemistry. 288, 10, p. 7012-7023 12 p.

Research output: Contribution to journalArticle

Myosin Light Chains
Myosins
Muscle
Skeletal Muscle
Muscle Contraction
4 Citations (Scopus)

Detection of hyaluronidase activity using fluorescence lifetime correlation spectroscopy to separate diffusing species and eliminate autofluorescence

Rich, R. M., Mummert, M., Gryczynski, Z., Borejdo, J., Gryczynski, I., Sørensen, T. J., Laursen, B. W. & Fudala, R., 28 May 2013, Single Molecule Spectroscopy and Superresolution Imaging VI. 859003. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8590).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hyaluronoglucosaminidase
Hyaluronic Acid
Spectrum Analysis
Macromolecules
macromolecules
38 Citations (Scopus)
Fluorophores
Fluorescence
Tissue
Coloring Agents
Biological Phenomena
19 Citations (Scopus)
Fluorophores
Fluorescence Spectrometry
Photons
Rhodamine 123
Fluorescence

Rotation of myosin lever arms during isometric contraction of skeletal myofibrils

Midde, K., Rich, R., Hohreiter, V., Raut, S., Luchowski, R., Hinze, C., Fudala, R., Gryczynski, I., Gryczynski, Z. & Borejdo, J., 1 Feb 2013, Skeletal Muscle: Physiology, Classification and Disease. Nova Science Publishers, Inc., p. 1-24 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Isometric Contraction
Myofibrils
Myosins
Fluorescence
Sarcomeres
2012
11 Citations (Scopus)
Hyaluronoglucosaminidase
Fluorescence Spectrometry
Hyaluronic Acid
Fluorescein
macromolecules
37 Citations (Scopus)

Imaging exocytosis of ATP-containing vesicles with TIRF microscopy in lung epithelial A549 cells

Akopova, I., Tatur, S., Grygorczyk, M., Luchowski, R., Gryczynski, I., Gryczynski, Z., Borejdo, J. & Grygorczyk, R., 1 Mar 2012, In : Purinergic Signalling. 8, 1, p. 59-70 12 p.

Research output: Contribution to journalArticle

Exocytosis
Microscopy
Adenosine Triphosphate
Epithelial Cells
Lung
9 Citations (Scopus)

Lifetime-based sensing of the hyaluronidase using fluorescein labeled hyaluronic acid

Fudala, R., Mummert, M. E., Gryczynski, Z., Rich, R., Borejdo, J. & Gryczynski, I., 5 Jan 2012, In : Journal of Photochemistry and Photobiology B: Biology. 106, 1, p. 69-73 5 p.

Research output: Contribution to journalArticle

Hyaluronoglucosaminidase
Hyaluronic Acid
Fluorescein
macromolecules
life (durability)
4 Citations (Scopus)

Mesoscopic analysis of motion and conformation of cross-bridges

Borejdo, J., Rich, R. & Midde, K., 1 Dec 2012, In : Biophysical Reviews. 4, 4, p. 299-311 13 p.

Research output: Contribution to journalReview article

Skeletal Muscle
Muscles
Electron Spin Resonance Spectroscopy
Myosins
Fluorescence Microscopy
3 Citations (Scopus)

Metal-enhanced immunoassays

Gryczynski, I., Luchowski, R., Matveeva, E. G., Shtoyko, T., Sarkar, P., Borejdo, J., Akopova, I. & Gryczynski, Z., 1 Jan 2012, Spectroscopic Methods of Analysis: Methods and Protocols. Humana Press Inc., p. 217-229 13 p. (Methods in Molecular Biology; vol. 875).

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunoassay
Fluorescence
Metals
Silver
Nanostructures
6 Citations (Scopus)

Single molecule detection approach to muscle study: Kinetics of a single cross-bridge during contraction of muscle

Borejdo, J., Szczesna-Cordary, D., Muthu, P., Metticolla, P., Luchowski, R., Gryczynski, Z. & Gryczynski, I., 1 Jan 2012, Spectroscopic Methods of Analysis: Methods and Protocols. Humana Press Inc., p. 311-334 24 p. (Methods in Molecular Biology; vol. 875).

Research output: Chapter in Book/Report/Conference proceedingChapter

Muscle Contraction
Familial Hypertrophic Cardiomyopathy
Actins
Myosins
Muscles
2011
17 Citations (Scopus)

Cross-bridge kinetics in myofibrils containing familial hypertrophic cardiomyopathy R58Q mutation in the regulatory light chain of myosin

Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z., Zhao, J., Szczesna-Cordary, D. & Borejdo, J., 7 Sep 2011, In : Journal of Theoretical Biology. 284, 1, p. 71-81 11 p.

Research output: Contribution to journalArticle

Familial Hypertrophic Cardiomyopathy
Cardiomyopathy
myosin light chains
Myosin Light Chains
Myosin
8 Citations (Scopus)

Evidence for pre-and post-power stroke of cross-bridges of contracting skeletal myofibrils

Midde, K., Luchowski, R., Das, H., Fedorick, J., Dumka, V., Gryczynski, I., Gryczynski, Z. & Borejdo, J., 16 Feb 2011, In : Biophysical Journal. 100, 4, p. 1024-1033 10 p.

Research output: Contribution to journalArticle

Myofibrils
Myosin Light Chains
Skeletal Muscle
Stroke
Myosins
17 Citations (Scopus)
Matrix Metalloproteinases
Fluorescence
Peptides
Enzymes
Fluorescence Resonance Energy Transfer
3 Citations (Scopus)

Fractal-like silver aggregates enhance the brightness and stability of single-molecule fluorescence

Luchowski, R., Shtoyko, T., Apicella, E., Sarkar, P., Akopova, I., Raut, S. L., Fudala, R., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 1 Feb 2011, In : Applied Spectroscopy. 65, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

antibodies
Silver
Antibodies
Fractals
Luminance
4 Citations (Scopus)

Myosin cross-bridges do not form precise rigor bonds in hypertrophic heart muscle carrying troponin t mutations

Midde, K., Dumka, V., Pinto, J. R., Muthu, P., Marandos, P., Gryczynski, I., Gryczynski, Z., Potter, J. D. & Borejdo, J., 1 Sep 2011, In : Journal of Molecular and Cellular Cardiology. 51, 3, p. 409-418 10 p.

Research output: Contribution to journalArticle

Troponin
Myosins
Myocardium
Troponin T
Mutation
1 Citation (Scopus)

Single actomyosin motor interactions in skeletal muscle

Földes-Papp, Z., Liao, S. C. J., Barbieri, B., Gryczynski, K., Luchowski, R., Gryczynski, Z., Gryczynski, I., Borejdo, J. & You, T., 1 May 2011, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1813, 5, p. 858-866 9 p.

Research output: Contribution to journalArticle

Actomyosin
Photons
Normal Distribution
Skeletal Muscle
Actins

Surface plasmon assisted microscopy: Reverse kretschmann fluorescence analysis of kinetics of hypertrophic cardiomyopathy heart

Borejdo, J., Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I. & Gryczynski, Z., 1 Feb 2011, Plasmons: Theory and Applications. Nova Science Publishers, Inc., p. 161-178 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

microscopy
fluorescence
kinetics
microscopes
myosins
2010
7 Citations (Scopus)

Familial hypertrophic cardiomyopathy can be characterized by a specific pattern of orientation fluctuations of actin molecules

Borejdo, J., Szczesna-Cordary, D., Muthu, P. & Calander, N., 29 Jun 2010, In : Biochemistry. 49, 25, p. 5269-5277 9 p.

Research output: Contribution to journalArticle

Familial Hypertrophic Cardiomyopathy
Actins
Molecules
Muscle
Myocardium
10 Citations (Scopus)

Fluorescence instrument response standards in two-photon time-resolved spectroscopy

Luchowski, R., Szabelski, M., Sarkar, P., Apicella, E., Midde, K., Raut, S. L., Borejdo, J., Gryczynski, Z. & Gryczynski, I., 1 Jan 2010, In : Applied Spectroscopy. 64, 8, p. 918-922 5 p.

Research output: Contribution to journalArticle

Photons
Fluorescence
Spectroscopy
life (durability)
fluorescence
12 Citations (Scopus)

Kinetics of a single cross-bridge in familial hypertrophic cardiomyopathy heart muscle measured by reverse Kretschmann fluorescence

Mettikolla, P., Calander, N., Luchowski, R., Gryczynski, I., Gryczynski, Z. & Borejdo, J., 1 Dec 2010, In : Journal of Biomedical Optics. 15, 1, 017011.

Research output: Contribution to journalArticle

muscles
myosins
Muscle
Actins
Myosins