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  • Robert Mallet
2019

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

Inline flow sensor for ventriculoperitoneal shunts: Experimental evaluation in swine

Qin, C., Olivencia-Yurvati, A. H., Williams, A. G., Eskildsen, D., Mallet, R. T. & Dasgupta, P. K., May 2019, In : Medical Engineering and Physics. 67, p. 66-72 7 p.

Research output: Contribution to journalArticle

Open Access

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

The Endocrine Kidney: Local and Systemic Actions of Renal Hormones

Mallet, R. T. & Ma, R., 23 Oct 2019, Hormonal Signaling in Biology and Medicine: Comprehensive Modern Endocrinology. Elsevier, p. 445-460 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

An in vitro oxygen–glucose deprivation model for studying ischemia–reperfusion injury of neuronal cells

Ryou, M. G. & Mallet, R. T., 1 Jan 2018, Methods in Molecular Biology. Humana Press Inc., p. 229-235 7 p. (Methods in Molecular Biology; vol. 1717).

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Cardioprotection by intermittent hypoxia conditioning: Evidence, mechanisms, and therapeutic potential

Mallet, R. T., Manukhina, E. B., Ruelas, S. S., Caffrey, J. L. & Downey, H. F., Aug 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 315, 2, p. H216-H232

Research output: Contribution to journalReview article

11 Scopus citations
4 Scopus citations

Pyruvate enhancement of cardiac performance: Cellular mechanisms and clinical application

Mallet, R. T., Olivencia-Yurvati, A. H. & Bünger, R., 1 Jan 2018, In : Experimental Biology and Medicine. 243, 2, p. 198-210 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Pyruvate-enriched resuscitation for shock

Mallet, R. T., Olivencia-Yurvati, A. H. & Bünger, R., 1 May 2018, In : Experimental Biology and Medicine. 243, 8, p. 663-664 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
2017

Enhanced cerebral perfusion during brief exposures to cyclic intermittent hypoxemia

Liu, X., Xu, D., Hall, J. R., Ross, S., Chen, S., Liu, H., Mallet, R. T. & Shi, X., 1 Dec 2017, In : Journal of applied physiology (Bethesda, Md. : 1985). 123, 6, p. 1689-1697 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Erythropoietin: Endogenous Protection of Ischemic Brain

Mallet, R. T., Ryou, M. G. & Ryou, M. G., 1 Jan 2017, Vitamins and Hormones. Academic Press Inc., p. 197-232 36 p. (Vitamins and Hormones; vol. 105).

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations

Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest

Scott, G. F., Nguyen, A. Q., Cherry, B. H., Hollrah, R. A., Salinas, I., Williams, A. G., Ryou, M. G. & Mallet, R. T., 1 Jan 2017, In : Experimental Biology and Medicine. 242, 10, p. 1095-1103 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
6 Scopus citations
2016

Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease

Manukhina, E. B., Downey, H. F., Shi, X. & Mallet, R. T., 1 Jun 2016, In : Experimental Biology and Medicine. 241, 12, p. 1351-1363 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Metabolomics and Receiver Operating Characteristic Analysis: A Promising Approach for Sepsis Diagnosis∗

Bünger, R. & Mallet, R. T., 1 Sep 2016, In : Critical Care Medicine. 44, 9, p. 1784-1785 2 p.

Research output: Contribution to journalEditorial

5 Scopus citations

δ-Opioid receptor (DOR) signaling and reactive oxygen species (ROS) mediate intermittent hypoxia induced protection of canine myocardium

Estrada, J. A., Williams, A. G., Sun, J., Gonzalez, L., Downey, H. F., Caffrey, J. L. & Mallet, R. T., 1 Mar 2016, In : Basic Research in Cardiology. 111, 2, p. 1-12 12 p., 17.

Research output: Contribution to journalArticle

10 Scopus citations

δ-Opioid receptors: Pivotal role in intermittent hypoxia-augmentation of cardiac parasympathetic control and plasticity

Estrada, J. A., Barlow, M. A., Yoshishige, D., Williams, A. G., Downey, H. F., Mallet, R. T. & Caffrey, J. L., 1 Jul 2016, In : Autonomic Neuroscience: Basic and Clinical. 198, p. 38-49 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2015

Pyruvate stabilizes electrocardiographic and hemodynamic function in pigs recovering from cardiac arrest

Cherry, B. H., Nguyen, A. Q., Hollrah, R. A., Williams, A. G., Hoxha, B., Yurvati, A. & Mallet, R. T., 1 Dec 2015, In : Experimental Biology and Medicine. 240, 12, p. 1774-1784 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Erythropoietin: Powerful protection of ischemic and post-ischemic brain

Nguyen, A. Q., Cherry, B. H., Scott, G. F., Ryou, M. G. & Mallet, R. T., 12 Nov 2014, In : Experimental Biology and Medicine. 239, 11, p. 1461-1475 15 p.

Research output: Contribution to journalArticle

50 Scopus citations

Neuronal injury from cardiac arrest: aging years in minutes

Cherry, B. H., Sumien, N. & Mallet, R. T., 1 Jan 2014, In : Age. 36, 4, 9680.

Research output: Contribution to journalArticle

1 Scopus citations

Novel split chest tube improves post-surgical thoracic drainage

Olivencia-Yurvati, A. H., Cherry, B. H., Gurji, H. A., White, D. W., Tyler Newton, J., Scott, G. F., Hoxha, B., Gourlay, T. & Mallet, R. T., 2014, In : Journal of Clinical and Experimental Cardiology. 5, 7

Research output: Contribution to journalArticle

Protective effects of adaptation to hypoxia in experimental Alzheimer's disease

Manukhina, E. B., Goryacheva, A. V., Pshennikova, M. G., Malyshev, I. Y., Mallet, R. T. & Downey, H. F., 1 May 2014, Intermittent Hypoxia and Human Diseases. Springer-Verlag London Ltd, p. 155-171 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Pyruvate-enriched resuscitation: Metabolic support of post-ischemic hindlimb muscle in hypovolemic goats

Gurji, H. A., White, D. W., Hoxha, B., Sun, J., Harbor, J. P., Schulz, D. R., Williams, A. G., Olivencia-Yurvati, A. H. & Mallet, R. T., 1 Feb 2014, In : Experimental Biology and Medicine. 239, 2, p. 240-249 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2013

Cyclosporine a cardioprotection: Mechanisms and potential for clinical application

Bünger, R. & Mallet, R. T., 1 Apr 2013, In : Critical Care Medicine. 41, 4, p. 1156-1158 3 p.

Research output: Contribution to journalEditorial

Intermittent hypoxia-induced cardio-and vasoprotection: Role of no stores

Manukhina, E. B., Vanin, A. F., Malyshev, I. Y., Mallet, R. T. & Downey, H. F., 1 Jan 2013, Intermittent Hypoxia: From Molecular Mechanisms To Clinical Applications. Nova Science Publishers, Inc., p. 79-112 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Normobaric, intermittent hypoxia conditioning is cardio- and vasoprotective in rats

Manukhina, E. B., Belkina, L. M., Terekhina, O. L., Abramochkin, D. V., Smirnova, E. A., Budanova, O. P., Mallet, R. T. & Downey, H. F., 1 Dec 2013, In : Experimental Biology and Medicine. 238, 12, p. 1413-1420 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation

Ryou, M. G., Choudhury, G. R., Winters, A., Xie, L., Mallet, R. T. & Yang, S. H., 12 Sep 2013, In : Brain Research. 1530, p. 66-75 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

β-Adrenergic signaling and ROS: Pivotal roles in intermittent, normobaric hypoxia-induced cardioprotection

Mallet, R. T., Ryou, M. G., Manukhina, E. B. & Downey, H. F., 1 Jan 2013, Intermittent Hypoxia: From Molecular Mechanisms To Clinical Applications. Nova Science Publishers, Inc., p. 151-174 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2012

[Role of restricted nitric oxide overproduction in the cardioprotective effect of adaptation to intermittent hypoxia].

goriacheva, A. V., Belkina, L. M., Terekhina, O. L., Dawney, H. F., Mallet, R. T., Smirin, B. V., Smirnova, E. A., Mashina, S. I. & Manukhina, E. B., 1 Jan 2012, In : Patologicheskaia fiziologiia i èksperimental'naia terapiia. 1, p. 23-28 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Inflammatory response and minimized cardiopulmonary bypass

Olivencia-Yurvati, A. H. & Mallet, R. T., 1 Jan 2012, Minimized Cardiopulmonary Bypass Techniques and Technologies. Elsevier Inc., p. 86-112 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Inflammatory response and minimized cardiopulmonary bypass

Yurvati, A. & Mallet, R. T., 1 Apr 2012, Minimized Cardiopulmonary Bypass Techniques and Technologies. Elsevier Inc., p. 86-112 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Inflammatory response and minimized cardiopulmonary bypass

Olivencia-Yurvati, A. H. & Mallet, R. T., 1 Jan 2012, Minimized Cardiopulmonary Bypass Techniques and Technologies. Elsevier Inc., p. 86-112 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Intermittent hypoxia conditioning protects mitochondrial cytochrome c oxidase of rat cerebellum from ethanol withdrawal stress

Ju, X., Mallet, R. T., Downey, H. F., Metzger, D. B. & Jung, M. E., 15 May 2012, In : Journal of Applied Physiology. 112, 10, p. 1706-1714 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Invited commentary

Mallet, R. T. & Yurvati, A., 1 Apr 2012, In : Annals of Thoracic Surgery. 93, 4, p. 1186-1187 2 p.

Research output: Contribution to journalComment/debate

Plagiarism

Goodman, S. R. & Mallet, R. T., 1 Jul 2012, In : Experimental Biology and Medicine. 237, 7, 1 p.

Research output: Contribution to journalEditorial

Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway

Ryou, M. G., Liu, R., Ren, M., Sun, J., Mallet, R. T. & Yang, S. H., 1 Apr 2012, In : Stroke. 43, 4, p. 1101-1107 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

Reply

Lyamina, N. P., Lyamina, S. V., Senchikhin, V. N., Mallet, R. T., Downey, H. F. & Manukhina, E. B., 1 Mar 2012, In : Journal of Hypertension. 30, 3, p. 626-627 2 p.

Research output: Contribution to journalLetter

2011

Gurji et al. respond

Gurji, H. A., White, D. W., Nelson, S., Daniels, E. Q., Yurvati, A. & Mallet, R. T., 1 Jul 2011, In : Lab Animal. 40, 7, p. 206-208 3 p.

Research output: Contribution to journalLetter

Intermittent hypoxia-induced cardio- and vasoprotection: Role of NO stores

Manukhina, E. B., Vanin, A. F., Malyshev, I. Y., Mallet, R. T. & Fred Downey, H., 1 Jan 2011, Intermittent Hypoxia: From Molecular Mechanisms To Clinical Applications. Nova Science Publishers, Inc., p. 79-112 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Intermittent hypoxia mobilizes hematopoietic progenitors and augments cellular and humoral elements of innate immunity in adult men

Serebrovskaya, T. V., Nikolsky, I. S., Nikolska, V. V., Mallet, R. T. & Ishchuk, V. A., 1 Oct 2011, In : High Altitude Medicine and Biology. 12, 3, p. 243-252 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Normobaric hypoxia conditioning reduces blood pressure and normalizes nitric oxide synthesis in patients with arterial hypertension

Lyamina, N. P., Lyamina, S. V., Senchiknin, V. N., Mallet, R. T., Downey, H. F. & Manukhina, E. B., 1 Nov 2011, In : Journal of Hypertension. 29, 11, p. 2265-2272 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

β-Adrenergic signaling and ROS: Pivotal roles in intermittent, normobaric hypoxia-induced cardioprotection

Mallet, R. T., Ryou, M. G., Manukhina, E. B. & Fred Downey, H., 1 Jan 2011, Intermittent Hypoxia: From Molecular Mechanisms To Clinical Applications. Nova Science Publishers, Inc., p. 151-174 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2010

Developments in cardiovascular valve technology

Yurvati, A., Mallet, R. T. & Fernandez, J., 1 Oct 2010, Biomaterials and Devices for the Circulatory System. Elsevier Inc., p. 89-122 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Peri- and intra-operative management of the goat during acute surgical experimentation

Flaherty, D. C., Hoxha, B., Nelson, S., Sun, J., Gurji, H., Simecka, J., Mallet, R. T., Yurvati, A. & Daniels, E. Q., 1 Mar 2010, In : Lab Animal. 39, 3, p. 80-85 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Pyruvate-enriched cardioplegia suppresses cardiopulmonary bypass-induced myocardial inflammation

Ryou, M. G., Flaherty, D. C., Hoxha, B., Gurji, H., Sun, J., Hodge, L. M., Olivencia-Yurvati, A. H. & Mallet, R. T., Nov 2010, In : Annals of Thoracic Surgery. 90, 5, p. 1529-1535 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

Pyruvate-enriched resuscitation protects hindlimb muscle from ischemia-reperfusion injury

Flaherty, D. C., Hoxha, B., Sun, J., Gurji, H., Simecka, J. W., Olivencia-Yurvati, A. H. & Mallet, R. T., Dec 2010, In : Military Medicine. 175, 12, p. 1020-1026 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
24 Scopus citations

Vagal modulation of heart rate variability during atrial fibrillation in pigs

Kneip, C. F., Mallet, R. T., Williams, A. G., Hamdan, M. H. & Smith, M. L., Aug 2010, In : Experimental Biology and Medicine. 235, 8, p. 1007-1014 8 p.

Research output: Contribution to journalArticle

4 Scopus citations