Find Research Outputs

Search concepts
Selected Filters
2019

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Oxidative stress
Young Adult
Oxidative Stress
Hemorrhage

Impact of environmental stressors on tolerance to hemorrhage in humans

Crandall, C. G., Rickards, C. A. & Johnson, B. D., 1 Feb 2019, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 316, 2, p. R88-R100

Research output: Contribution to journalReview articleResearchpeer-review

Lower Body Negative Pressure
Hemorrhage
Altitude Sickness
Hypovolemia
Military Personnel

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental Physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Ischemic Preconditioning
Exercise
Clinical Trials
Hypoxia-Inducible Factor 1
Microglia

Responses of cerebral blood velocity and tissue oxygenation to low-frequency oscillations during simulated haemorrhagic stress in humans

Anderson, G. K., Sprick, J. D., Park, F. S., Rosenberg, A. J. & Rickards, C. A., 1 Jan 2019, In : Experimental Physiology.

Research output: Contribution to journalArticleResearchpeer-review

Arterial Pressure
Middle Cerebral Artery
Hypovolemia
Frontal Lobe
Stroke Volume

Vive la résistance! The role of inspiratory resistance breathing on cerebral blood flow

Rickards, C. A., 1 Jul 2019, In : Respiratory Physiology and Neurobiology. 265, p. 76-82 7 p.

Research output: Contribution to journalReview articleResearchpeer-review

Cerebrovascular Circulation
Heart Arrest
Respiration
Hemorrhage
Intracranial Pressure
2018

Time course of compensatory physiological responses to central hypovolemia in high-and low-tolerant human subjects

Xiang, L., Hinojosa-Laborde, C., Ryan, K. L., Rickards, C. A. & Convertino, V. A., 20 Aug 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 2, p. R408-R416

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Vascular Resistance
Heart Rate
Syncope
Myocardium
2017
3 Citations (Scopus)

Cerebral oxygenation and regional cerebral perfusion responses with resistance breathing during central hypovolemia

Kay, V. L., Sprick, J. D. & Rickards, C. A., 1 Jan 2017, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 313, 2, p. R132-R139

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Cerebrovascular Circulation
Respiration
Perfusion
Electric Impedance
4 Citations (Scopus)
Ischemic Preconditioning
Exercise
Reperfusion
Arterial Pressure
Norepinephrine
4 Citations (Scopus)
Ischemic Preconditioning
Middle Cerebral Artery
Reperfusion
Norepinephrine
Arterial Pressure
2016
6 Citations (Scopus)

The effects of superimposed tilt and lower body negative pressure on anterior and posterior cerebral circulations

Tymko, M. M., Rickards, C. A., Skow, R. J., Ingram-Cotton, N. C., Howatt, M. K. & Day, T. A., 1 Sep 2016, In : Physiological Reports. 4, 17, e12957.

Research output: Contribution to journalArticleResearchpeer-review

Cerebrovascular Circulation
Lower Body Negative Pressure
Blood Volume
Intracranial Pressure
Head-Down Tilt
1 Citation (Scopus)

The efficacy of novel anatomical sites for the assessment of muscle oxygenation during central hypovolemia

Sprick, J. D., Soller, B. R. & Rickards, C. A., 1 Nov 2016, In : Experimental Biology and Medicine. 241, 17, p. 2007-2013 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Oxygenation
Superficial Back Muscles
Lower Body Negative Pressure
Muscle
14 Citations (Scopus)

The role of cerebral oxygenation and regional cerebral blood flow on tolerance to central hypovolemia

Kay, V. L. & Rickards, C. A., 1 Feb 2016, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 310, 4, p. R375-R383

Research output: Contribution to journalArticleResearchpeer-review

Cerebrovascular Circulation
Central Tolerance
Lower Body Negative Pressure
Hypovolemia
Regional Blood Flow
2015
6 Citations (Scopus)

Acute inhalation of vaporized nicotine increases arterial pressure in young non-smokers: a pilot study

Cooke, W. H., Pokhrel, A., Dowling, C., Fogt, D. L. & Rickards, C. A., 22 Aug 2015, In : Clinical Autonomic Research. 25, 4, p. 267-270 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Nicotine
Inhalation
Arterial Pressure
Posture
Longitudinal Studies
16 Citations (Scopus)

Cerebral blood-flow regulation during hemorrhage

Rickards, C. A., 1 Oct 2015, In : Comprehensive Physiology. 5, 4, p. 1585-1621 37 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebrovascular Circulation
Hemorrhage
Perfusion
Hemorrhagic Disorders
Brain Hypoxia-Ischemia
14 Citations (Scopus)

Cerebral blood velocity regulation during progressive blood loss compared with lower body negative pressure in humans

Rickards, C. A., Johnson, B. D., Harvey, R. E., Convertino, V. A., Joyner, M. J. & Barnes, J. N., 1 Jan 2015, In : Journal of Applied Physiology. 119, 6, p. 677-685 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Middle Cerebral Artery
Arterial Pressure
Central Venous Pressure
Cerebrovascular Circulation
7 Citations (Scopus)

Coupling between arterial pressure, cerebral blood velocity, and cerebral tissue oxygenation with spontaneous and forced oscillations

Rickards, C. A., Sprick, J. D., Colby, H. B., Kay, V. L. & Tzeng, Y. C., 1 Apr 2015, In : Physiological Measurement. 36, 4, p. 785-801 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Oxygenation
Blood pressure
Arterial Pressure
Tissue

Graduate students and postdoctoral fellows receive Tum Suden/Hellebrandt professional opportunity awards

Rickards, C. A., 1 Jan 2015, In : Physiologist. 58, 5, p. 250-251 2 p.

Research output: Contribution to journalComment/debateResearch

Students
6 Citations (Scopus)

Reproducibility of a continuous ramp lower body negative pressure protocol for simulating hemorrhage

Kay, V. L. & Rickards, C. A., 1 Nov 2015, In : Physiological Reports. 3, 11, e12640.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Architectural Accessibility
Syncope
Hemorrhage
Hypovolemia
93 Citations (Scopus)

Transfer function analysis of dynamic cerebral autoregulation: A white paper from the International Cerebral Autoregulation Research Network

international Cerebral Autoregulation Research Network (CARNet), 1 Jan 2015, In : Journal of Cerebral Blood Flow and Metabolism. 36, 4, p. 665-680 16 p.

Research output: Contribution to journalReview articleResearchpeer-review

Homeostasis
Research
Blood Pressure
Cerebrovascular Circulation
Perfusion
2014
8 Citations (Scopus)

Are you bleeding? Validation of a machine-learning algorithm for determination of blood volume status: Application to remote triage

Rickards, C. A., Vyas, N., Ryan, K. L., Ward, K. R., Andre, D., Hurst, G. M., Barrera, C. R. & Convertino, V. A., 1 Mar 2014, In : Journal of Applied Physiology. 116, 5, p. 486-494 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Blood Volume Determination
Lower Body Negative Pressure
Triage
Stroke Volume
Exercise
25 Citations (Scopus)

Arterial pressure and cerebral blood flow variability: Friend or foe? A review

Rickards, C. A. & Tzeng, Y. C., 1 Jan 2014, In : Frontiers in Physiology. 5 APR, Article 120.

Research output: Contribution to journalReview articleResearchpeer-review

Cerebrovascular Circulation
Arterial Pressure
Hemodynamics
Perfusion
Hypovolemia
27 Citations (Scopus)

Between-centre variability in transfer function analysis, a widely used method for linear quantification of the dynamic pressure-flow relation: The CARNet study

Meel-van den Abeelen, A. S. S., Simpson, D. M., Wang, L. J. Y., Slump, C. H., Zhang, R., Tarumi, T., Rickards, C. A., Payne, S., Mitsis, G. D., Kostoglou, K., Marmarelis, V., Shin, D., Tzeng, Y. C., Ainslie, P. N., Gommer, E., Müller, M., Dorado, A. C., Smielewski, P., Yelicich, B., Puppo, C. & 6 others, Liu, X., Czosnyka, M., Wang, C. Y., Novak, V., Panerai, R. B. & Claassen, J. A. H. R., 1 Jan 2014, In : Medical Engineering and Physics. 36, 5, p. 620-627 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cerebrovascular Circulation
Transfer functions
Blood Flow Velocity
Hypercapnia
Pressure

Blood pressure and cerebral blood flow oscillations: Friend or foe?

Rickards, C. A. & Tzeng, Y. C., 1 Jan 2014, 2014 8th Conference of the European Study Group on Cardiovascular Oscillations, ESGCO 2014. IEEE Computer Society, p. 179-180 2 p. 6847578

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Blood pressure
Hemodynamics
Blood
Oxygenation
Surgery
5 Citations (Scopus)

Platelet activation after presyncope by lower body negative pressure in humans

Zaar, M., Fedyk, C. G., Pidcoke, H. F., Scherer, M. R., Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Convertino, V. A. & Cap, A. P., 29 Dec 2014, In : PLoS ONE. 9, 12, e116174.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
platelet activation
Platelet Activation
Syncope
Platelets
2013

Far from home challenges facing international graduate students, postdocs, & professionals living and working in the US

Rickards, C. A., 1 Mar 2013, In : Physiologist. 56, 2, p. 50-52 3 p.

Research output: Contribution to journalComment/debateResearch

Cultural Characteristics
Graduate Education
Career Choice
Loneliness
Job Satisfaction
11 Citations (Scopus)

Heart rate variability analysis during central hypovolemia using wavelet transformation

Ji, S. Y., Belle, A., Ward, K. R., Ryan, K. L., Rickards, C. A., Convertino, V. A. & Najarian, K., 1 Jun 2013, In : Journal of Clinical Monitoring and Computing. 27, 3, p. 289-302 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Wavelet Analysis
Hypovolemia
Fractals
Heart Rate
Lower Body Negative Pressure
2012
4 Citations (Scopus)

A recipe for reducing blood pressure variability: Adding blood flow to the mix

Tzeng, Y. C., MacRae, B. & Rickards, C. A., 1 Aug 2012, In : Hypertension. 60, 2

Research output: Contribution to journalLetterResearchpeer-review

Azetidinecarboxylic Acid
Tetrazoles
Imidazoles
Dihydropyridines
Hydrochlorothiazide
79 Citations (Scopus)

Assessment of cerebral autoregulation: The quandary of quantification

Tzeng, Y. C., Ainslie, P. N., Cooke, W. H., Peebles, K. C., Willie, C. K., MacRae, B. A., Smirl, J. D., Horsman, H. M. & Rickards, C. A., 15 Sep 2012, In : American Journal of Physiology - Heart and Circulatory Physiology. 303, 6

Research output: Contribution to journalArticleResearchpeer-review

Homeostasis
Blood Pressure
Middle Cerebral Artery
Thigh
41 Citations (Scopus)

Autonomic mechanisms associated with heart rate and vasoconstrictor reserves

Convertino, V. A., Rickards, C. A. & Ryan, K. L., 1 Jun 2012, In : Clinical Autonomic Research. 22, 3, p. 123-130 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Vasoconstrictor Agents
Central Tolerance
Hypovolemia
Baroreflex

Early detection of hemorrhage via central pulse pressure derived from a non-invasive peripheral arterial blood pressure waveform

Zhang, G., Ryan, K. L., Rickards, C. A., Convertino, V. A. & Mukkamala, R., 14 Dec 2012, 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012. p. 3116-3119 4 p. 6346624. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Blood pressure
Arterial Pressure
Hemorrhage
Blood Pressure
Lower Body Negative Pressure
12 Citations (Scopus)

Effects of dehydration on cerebrovascular control during standing after heavy resistance exercise

Moralez, G., Romero, S. A., Rickards, C. A., Ryan, K. L., Convertino, V. A. & Cooke, W. H., 1 Jun 2012, In : Journal of Applied Physiology. 112, 11, p. 1875-1883 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Middle Cerebral Artery
Dehydration
Arterial Pressure
Plasma Volume
Furosemide
16 Citations (Scopus)

Lightweight noninvasive trauma monitor for early indication of central hypovolemia and tissue acidosis: A review

Soller, B. R., Zou, F., Ryan, K. L., Rickards, C. A., Ward, K. & Convertino, V. A., 1 Aug 2012, In : Journal of Trauma and Acute Care Surgery. 73, 2 SUPPL. 1

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Hypovolemia
Acidosis
Stroke Volume
Vital Signs
4 Citations (Scopus)

Progressive reduction in central blood volume is not detected by sublingual capnography

Chung, K. K., Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Pamplin, J. C., Patel, S. S., Herold, T. S. & Convertino, V. A., 1 Jun 2012, In : Shock. 37, 6, p. 586-591 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Capnography
Blood Volume
Lower Body Negative Pressure
Hypovolemia
Blood Pressure

Reply from K. L. Ryan, C. A. Rickards, C. Hinojosa-Laborde, W. H. Cooke and V. A. Convertino

Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Cooke, W. H. & Convertino, V. A., 1 Feb 2012, In : Journal of Physiology. 590, 3, p. 649 1 p.

Research output: Contribution to journalLetterResearchpeer-review

4 Citations (Scopus)

Simultaneous spectroscopic determination of forearm muscle pH and oxygen saturation during simulated haemorrhage

Soller, B. R., Sliwa, J., Yang, Y., Zou, F., Ryan, K. L., Rickards, C. A. & Convertino, V. A., 2 Apr 2012, In : Journal of Near Infrared Spectroscopy. 20, 1, p. 141-150 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Muscle
Oxygen
Infrared radiation
Blood
Scattering
21 Citations (Scopus)

Sympathetic responses to central hypovolemia: New insights from microneurographic recordings

Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Cooke, W. H. & Convertino, V. A., 20 Sep 2012, In : Frontiers in Physiology. 3 APR, Article 110.

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Muscles
Lower Body Negative Pressure
Hemorrhage
Baroreflex
2011
5 Citations (Scopus)

Advanced technology development for remote triage applications in bleeding combat casualties.

Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Gerhardt, R. T., Cain, J. & Convertino, V. A., 1 Apr 2011, In : U.S. Army Medical Department journal. p. 61-72 12 p.

Research output: Contribution to journalReview articleResearchpeer-review

Triage
Hemorrhage
Exercise
Equipment and Supplies
Hypovolemia
21 Citations (Scopus)

Arterial pressure oscillations are not associated with muscle sympathetic nerve activity in individuals exposed to central hypovolaemia

Ryan, K. L., Rickards, C. A., Hinojosa-Laborde, C., Cooke, W. H. & Convertino, V. A., 1 Nov 2011, In : Journal of Physiology. 589, 21, p. 5311-5322 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Arterial Pressure
Muscles
Lower Body Negative Pressure
Blood Pressure
18 Citations (Scopus)

Control of cerebral blood velocity with furosemide-induced hypovolemia and upright tilt

Romero, S. A., Moralez, G., Rickards, C. A., Ryan, K. L., Convertino, V. A., Fogt, D. L. & Cooke, W. H., 1 Feb 2011, In : Journal of Applied Physiology. 110, 2, p. 492-498 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Furosemide
Arterial Pressure
Baroreflex
Dehydration
19 Citations (Scopus)

Heart rate variability during simulated hemorrhage with lower body negative pressure in high and low tolerant subjects

Hinojosa-Laborde, C., Rickards, C. A., Ryan, K. L. & Convertino, V. A., 1 Dec 2011, In : Frontiers in Physiology. 2 NOV, Article 85.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Heart Rate
Hemorrhage
Syncope
Hypovolemia
20 Citations (Scopus)

Improved pulse transit time estimation by system identification analysis of proximal and distal arterial waveforms

Xu, D., Ryan, K. L., Rickards, C. A., Zhang, G., Convertino, V. A. & Mukkamala, R., 1 Oct 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 301, 4

Research output: Contribution to journalArticleResearchpeer-review

Pulse Wave Analysis
Impedance Cardiography
Blood Pressure
Foot
Lower Body Negative Pressure
38 Citations (Scopus)

Monitoring non-invasive cardiac output and stroke volume during experimental human hypovolaemia and resuscitation.

Reisner, A. T., Xu, D., Ryan, K. L., Convertino, V. A., Rickards, C. A. & Mukkamala, R., 1 Jan 2011, In : British journal of anaesthesia. 106, 1, p. 23-30 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Cardiac Volume
Hypovolemia
Lower Body Negative Pressure
Resuscitation
Cardiac Output
30 Citations (Scopus)

Optimizing the respiratory pump: Harnessing inspiratory resistance to treat systemic hypotension

Convertino, V. A., Ryan, K. L., Rickards, C. A., Glorsky, S. L., Idris, A. H., Yannopoulos, D., Metzger, A. & Lurie, K. G., 1 Jun 2011, In : Respiratory Care. 56, 6, p. 846-857 12 p.

Research output: Contribution to journalReview articleResearchpeer-review

Hypotension
Pressure
Cerebrovascular Circulation
Respiration
Heat Stroke
48 Citations (Scopus)

Pulse oximeter plethysmographic waveform changes in awake, spontaneously breathing, hypovolemic volunteers

McGrath, S. P., Ryan, K. L., Wendelken, S. M., Rickards, C. A. & Convertino, V. A., 1 Feb 2011, In : Anesthesia and Analgesia. 112, 2, p. 368-374 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Hypovolemia
Pulse
Volunteers
Respiration
Lower Body Negative Pressure
55 Citations (Scopus)

Tolerance to central hypovolemia: the influence of oscillations in arterial pressure and cerebral blood velocity

Rickards, C. A., Ryan, K. L., Cooke, W. H. & Convertino, V. A., 1 Oct 2011, In : Journal of Applied Physiology. 111, 4, p. 1048-1058 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Central Tolerance
Hypovolemia
Arterial Pressure
Lower Body Negative Pressure
Middle Cerebral Artery
59 Citations (Scopus)

Use of advanced machine-learning techniques for noninvasive monitoring of hemorrhage

Convertino, V. A., Moulton, S. L., Grudic, G. Z., Rickards, C. A., Hinojosa-Laborde, C., Gerhardt, R. T., Blackbourne, L. H. & Ryan, K. L., 1 Jul 2011, In : Journal of Trauma - Injury, Infection and Critical Care. 71, SUPPL. 1

Research output: Contribution to journalReview articleResearchpeer-review

Blood Volume
Hemorrhage
Hemodynamics
Lower Body Negative Pressure
Shock
2010
20 Citations (Scopus)

Characterization of common measures of heart period variability in healthy human subjects: Implications for patient monitoring

Rickards, C. A., Ryan, K. L. & Convertino, V. A., 1 Feb 2010, In : Journal of Clinical Monitoring and Computing. 24, 1, p. 61-70 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Physiologic Monitoring
Healthy Volunteers
Electrocardiography
Demography
Hemorrhage
12 Citations (Scopus)

Ectopy in trauma patients: Cautions for use of heart period variability in medical monitoring

Sethuraman, G., Ryan, K. L., Rickards, C. A. & Convertino, V. A., 1 Feb 2010, In : Aviation Space and Environmental Medicine. 81, 2, p. 125-129 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Wounds and Injuries
Healthy Volunteers
Electrocardiography
Lower Body Negative Pressure
Noise
23 Citations (Scopus)

Is heart period variability associated with the administration of lifesaving interventions in individual prehospital trauma patients with normal standard vital signs?

Rickards, C. A., Ryan, K. L., Ludwig, D. A. & Convertino, V. A., 1 Jan 2010, In : Critical Care Medicine. 38, 8, p. 1666-1673 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Vital Signs
Wounds and Injuries
Aircraft
Trauma Centers
Fractals
48 Citations (Scopus)

Oxygen transport characterization of a human model of progressive hemorrhage

Ward, K. R., Tiba, M. H., Ryan, K. L., Torres Filho, I. P., Rickards, C. A., Witten, T., Soller, B. R., Ludwig, D. A. & Convertino, V. A., 1 Aug 2010, In : Resuscitation. 81, 8, p. 987-993 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lower Body Negative Pressure
Hemorrhage
Oxygen
Shock
Perfusion