Find Research Outputs

Search in all content

Filters for Publications

Search concepts
Selected Filters
Clear all

Publication Year

  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010

Author

  • Jerry Simecka
2019

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, W. P., Simecka, J. W., Raut, S., Ray, A. & Basha, R., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journal › Article

1 Scopus citations

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journal › Article

2 Scopus citations

Primary care clinics can be a source of exposure to virulent Clostridium (now Clostridioides) difficile: An environmental screening study of hospitals and clinics in Dallas-Fort Worth region

Simecka, J. W., Fulda, K. G., Pulse, M., Lee, J. H., Vitucci, J., Nguyen, P., Taylor, P., Filipetto, F., Espinoza, A. M. & Sharma, S., 1 Jan 2019, In : PLoS ONE. 14, 8, e0220646.

Research output: Contribution to journal › Article

Open Access
1 Scopus citations
2018

Activity of meropenem-vaborbactam against carbapenem- resistant enterobacteriaceae in a murine model of pyelonephritis

Weiss, W. J., Pulse, M. E., Nguyen, P., Peterson, K., Silva, J., Simecka, J. W., Valtierra, D., Sabet, M. & Griffith, D. C., Jan 2018, In : Antimicrobial agents and chemotherapy. 62, 1, e01439.

Research output: Contribution to journal › Article

8 Scopus citations

Interleukin-17A exacerbates disease severity in BALB/c mice susceptible to lung infection with Mycoplasma pulmonis

Mize, M. T., Sun, X. L. & Simecka, J. W., 1 Sep 2018, In : Infection and Immunity. 86, 9, e00292-18.

Research output: Contribution to journal › Article

5 Scopus citations
2016

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation

Sankpal, U. T., Ingersoll, S. B., Ahmad, S., Holloway, R. W., Bhat, V. B., Simecka, J. W., Daniel, L., Kariali, E., Vishwanatha, J. K. & Basha, R., 1 Oct 2016, In : Tumor Biology. 37, 10, p. 14259-14269 11 p.

Research output: Contribution to journal › Article

15 Scopus citations

Combination of Tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species

Sankpal, U. T., Nagaraju, G. P., Gottipolu, S. R., Hurtado, M., Jordan, C. G., Simecka, J. W., Shoji, M., El-Rayes, B. & Basha, R., 1 Jan 2016, In : Oncotarget. 7, 3, p. 3186-3200 15 p.

Research output: Contribution to journal › Article

33 Scopus citations

Regulatory CD4+ CD25+ T cells dampen inflammatory disease in murine mycoplasma pneumonia and promote IL-17 and IFN-γ Responses

Odeh, A. N. & Simecka, J. W., May 2016, In : PLoS ONE. 11, 5, e0155648.

Research output: Contribution to journal › Article

10 Scopus citations

Small molecule tolfenamic acid and dietary spice curcumin treatment enhances antiproliferative effect in pancreatic cancer cells via suppressing Sp1, disrupting NF-kB translocation to nucleus and cell cycle phase distribution

Basha, R., Connelly, S. F., Sankpal, U. T., Nagaraju, G. P., Patel, H., Vishwanatha, J. K., Shelake, S., Tabor-Simecka, L., Shoji, M., Simecka, J. W. & El-Rayes, B., 1 May 2016, In : Journal of Nutritional Biochemistry. 31, p. 77-87 11 p.

Research output: Contribution to journal › Article

22 Scopus citations

Thiopurine prodrugs mediate immunosuppressive effects by interfering with Rac1 protein function

Shin, J. Y., Wey, M., Umutesi, H. G., Sun, X., Simecka, J. & Heo, J., 24 Jun 2016, In : Journal of Biological Chemistry. 291, 26, p. 13699-13714 16 p.

Research output: Contribution to journal › Article

13 Scopus citations
2014

Antigen-pulsed bone marrow-derived and pulmonary dendritic cells promote Th2 cell responses and immunopathology in lungs during the pathogenesis of murine mycoplasma pneumonia

Dobbs, N. A., Zhou, X., Pulse, M., Hodge, L. M., Schoeb, T. R. & Simecka, J., 1 Aug 2014, In : Journal of Immunology. 193, 3, p. 1353-1363 11 p.

Research output: Contribution to journal › Article

5 Scopus citations
2013

Dendritic Cells Are the Major Antigen Presenting Cells in Inflammatory Lesions of Murine Mycoplasma Respiratory Disease

Sun, X., Jones, H. P., Dobbs, N., Bodhankar, S. & Simecka, J. W., 4 Feb 2013, In : PLoS ONE. 8, 2, e55984.

Research output: Contribution to journal › Article

11 Scopus citations

Interleukin-23 (IL-23) deficiency disrupts Th17 and Th1-related defenses against Streptococcus pneumoniae infection

Kim, B. J., Lee, S., Berg, R. E., Simecka, J. W. & Jones, H. P., 1 Oct 2013, In : Cytokine. 64, 1, p. 375-381 7 p.

Research output: Contribution to journal › Article

15 Scopus citations

Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252

Parsons, J. B., Kukula, M., Jackson, P., Pulse, M., Simecka, J., Valtierra, D., Weiss, W., Kaplan, N. & Rock, C. O., 1 May 2013, In : Antimicrobial agents and chemotherapy. 57, 5, p. 2182-2190 9 p.

Research output: Contribution to journal › Article

25 Scopus citations

What we have learned from animal models of Mycoplasma pneumoniae disease: Virulence mechanisms and host responses

Simecka, J. W., Dec 2013, In : Current Pediatric Reviews. 9, 4, p. 314-323 10 p.

Research output: Contribution to journal › Review article

2 Scopus citations
2012

Oral Inoculation of Young Dairy Calves with Mycoplasma bovis Results in Colonization of Tonsils, Development of Otitis Media and Local Immunity

Maunsell, F., Brown, M. B., Powe, J., Ivey, J., Woolard, M., Love, W. & Simecka, J. W., 6 Sep 2012, In : PLoS ONE. 7, 9, e44523.

Research output: Contribution to journal › Article

26 Scopus citations
2011

Corticotropin-releasing hormone receptor-1 and 2 activity produces divergent resistance against stress-induced pulmonary Streptococcus pneumoniae infection

Kim, B. J., Kayembe, K., Simecka, J. W., Pulse, M. & Jones, H. P., 15 Aug 2011, In : Journal of Neuroimmunology. 237, 1-2, p. 57-65 9 p.

Research output: Contribution to journal › Article

10 Scopus citations

Small molecule inhibitors of staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis

Olson, P. D., Kuechenmeister, L. J., Anderson, K. L., Daily, S., Beenken, K. E., Roux, C. M., Reniere, M. L., Lewis, T. L., Weiss, W. J., Pulse, M., Nguyen, P., Simecka, J. W., Morrison, J. M., Sayood, K., Asojo, O. A., Smeltzer, M. S., Skaar, E. P. & Dunman, P. M., 1 Feb 2011, In : PLoS Pathogens. 7, 2, e1001287.

Research output: Contribution to journal › Article

41 Scopus citations
2010

Interferon γ and interleukin 4 have contrasting effects on immunopathology and the development of protective adaptive immunity against mycoplasma respiratory disease

Bodhankar, S., Sun, X. L., Woolard, M. D. & Simecka, J., 1 Jul 2010, In : Journal of Infectious Diseases. 202, 1, p. 39-51 13 p.

Research output: Contribution to journal › Article

14 Scopus citations

Peri- and intra-operative management of the goat during acute surgical experimentation

Flaherty, D. C., Hoxha, B., Nelson, S., Sun, J., Gurji, H., Simecka, J., Mallet, R. T., Yurvati, A. & Daniels, E. Q., 1 Mar 2010, In : Lab Animal. 39, 3, p. 80-85 6 p.

Research output: Contribution to journal › Article

8 Scopus citations

Pyruvate-enriched resuscitation protects hindlimb muscle from ischemia-reperfusion injury

Flaherty, D. C., Hoxha, B., Sun, J., Gurji, H., Simecka, J. W., Olivencia-Yurvati, A. H. & Mallet, R. T., Dec 2010, In : Military Medicine. 175, 12, p. 1020-1026 7 p.

Research output: Contribution to journal › Article

4 Scopus citations

Pyruvate-fortified fluid resuscitation improves hemodynamic stability while suppressing systemic inflammation and myocardial oxidative strees after hemorrhagic shock

Flaherty, D. C., Hoxha, B., Sun, J., Gurji, H., Simecka, J. W., Mallet, R. T. & Olivencia-Yurvati, A. H., 1 Jan 2010, In : Military Medicine. 175, 3, p. 166-172 7 p.

Research output: Contribution to journal › Article

24 Scopus citations

Toll-like receptor 2 (TLR2) plays a major role in innate resistance in the lung against murine mycoplasma

Love, W., Dobbs, N., Tabor, L. & Simecka, J. W., 17 Sep 2010, In : PLoS ONE. 5, 5, e10739.

Research output: Contribution to journal › Article

27 Scopus citations