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2019
1 Citation (Scopus)

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, P., Simecka, J., Raut, S. L., Ray, A. & Basha, R. M., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Vincristine
Cells
Caspase 7
Cell Survival

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, W. P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticle

Medulloblastoma
Vincristine
tolfenamic acid
Cell Cycle
Apoptosis

Randomized assessment of delayed intensification and two methods for parenteral methotrexate delivery in childhood B-ALL: Children’s Oncology Group Studies P9904 and P9905

Winick, N., Martin, P. L., Devidas, M., Shuster, J., Borowitz, M. J., Paul Bowman, W., Larsen, E., Pullen, J., Carroll, A., Willman, C., Hunger, S. P., Carroll, W. L. & Camitta, B. M., 1 Jan 2019, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Methotrexate
Residual Neoplasm
National Cancer Institute (U.S.)
Random Allocation
2018
1 Citation (Scopus)

Early Nutrition Intervention Attenuates Weight Gain for Pediatric Acute Lymphoblastic Leukemia Patients in Maintenance Therapy

Hill, R., Hamby, T., Bashore, L., Rapisand, S., Galipp, K., Heym, K. & Bowman, P., 1 Jan 2018, In : Journal of Pediatric Hematology/Oncology. 40, 2, p. 104-110 7 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Weight Gain
Pediatrics
Therapeutics
Body Mass Index
28 Citations (Scopus)

Germline Genetic IKZF1 Variation and Predisposition to Childhood Acute Lymphoblastic Leukemia

Churchman, M. L., Qian, M., te Kronnie, G., Zhang, R., Yang, W., Zhang, H., Lana, T., Tedrick, P., Baskin, R., Verbist, K., Peters, J. L., Devidas, M., Larsen, E., Moore, I. M., Gu, Z., Qu, C., Yoshihara, H., Porter, S. N., Pruett-Miller, S. M., Wu, G. & 16 others, Raetz, E., Martin, P. L., Bowman, W. P., Winick, N., Mardis, E., Fulton, R., Stanulla, M., Evans, W. E., Relling, M. V., Pui, C. H., Hunger, S. P., Loh, M. L., Handgretinger, R., Nichols, K. E., Yang, J. J. & Mullighan, C. G., 14 May 2018, In : Cancer Cell. 33, 5, p. 937-948.e8

Research output: Contribution to journalArticle

Genetic Predisposition to Disease
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Cell Communication
Computer Simulation
Protein-Tyrosine Kinases

Therapeutic leukocytapheresis in infants and children with leukemia and hyperleukocytosis: A single institution experience

Thapa, N., Pham, R., Cole, C., Meinershagen, M., Bowman, P. & Ray, A., 1 Jun 2018, In : Journal of Clinical Apheresis. 33, 3, p. 316-323 8 p.

Research output: Contribution to journalArticle

Leukapheresis
Leukemia
Leukocyte Count
Pediatrics
Therapeutics
31 Citations (Scopus)

TP53 germline variations influence the predisposition and prognosis of b-cell acute lymphoblastic leukemia in children

Qian, M., Cao, X., Devidas, M., Yang, W., Cheng, C., Dai, Y., Carroll, A., Heerema, N. A., Zhang, H., Moriyama, T., Gastier-Foster, J. M., Xu, H., Raetz, E., Larsen, E., Winick, N., Bowman, W. P., Martin, P. L., Mardis, E. R., Fulton, R., Zambetti, G. & 11 others, Borowitz, M., Wood, B., Nichols, K. E., Carroll, W. L., Pui, C. H., Mullighan, C. G., Evans, W. E., Hunger, S. P., Relling, M. V., Loh, M. L. & Yang, J. J., 20 Feb 2018, In : Journal of Clinical Oncology. 36, 6, p. 591-599 9 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Li-Fraumeni Syndrome
Second Primary Neoplasms
Computer Simulation
Disease-Free Survival
2017
34 Citations (Scopus)

Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with Response-Adapted therapy

Pui, C. H., Pei, D., Raimondi, S. C., Coustan-Smith, E., Jeha, S., Cheng, C., Bowman, W. P., Sandlund, J. T., Ribeiro, R. C., Rubnitz, J. E., Inaba, H., Gruber, T. A., Leung, W. H., Yang, J. J., Downing, J. R., Evans, W. E., Relling, M. V. & Campana, D., 1 Feb 2017, In : Leukemia. 31, 2, p. 333-339 7 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
National Cancer Institute (U.S.)
Biphenotypic Acute Leukemia
Polyploidy
2 Citations (Scopus)

Pleuropulmonary blastoma: A single-center case series of 6 patients

Pierce, J. M., Lacroix, P., Heym, K., Bowman, P., Margraf, L., Iglesias, J. & Ray, A., 1 Jan 2017, In : Journal of Pediatric Hematology/Oncology. 39, 8, p. e419-e422

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
Lung
Mutation
Germ-Line Mutation
10 Citations (Scopus)

Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth

Shelake, S., Sankpal, U. T., Bowman, P., Wise, M., Ray, A. & Basha, R. M., 1 Apr 2017, In : Investigational New Drugs. 35, 2, p. 158-165 8 p.

Research output: Contribution to journalArticle

Sp1 Transcription Factor
Ewing's Sarcoma
Growth
Neoplasms
Proteasome Inhibitors
2016
28 Citations (Scopus)

Clinical and genetic risk factors for acute pancreatitis in patients with acute lymphoblastic leukemia

Liu, C., Yang, W., Devidas, M., Cheng, C., Pei, D., Smith, C., Carroll, W. L., Raetz, E. A., Bowman, W. P., Larsen, E. C., Maloney, K. W., Martin, P. L., Mattano, L. A., Winick, N. J., Mardis, E. R., Fulton, R. S., Bhojwani, D., Howard, S. C., Jeha, S., Pui, C. H. & 4 others, Hunger, S. P., Evans, W. E., Loh, M. L. & Relling, M. V., 20 Jun 2016, In : Journal of Clinical Oncology. 34, 18, p. 2133-2140 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pancreatitis
Asparaginase
North American Indians
Genome-Wide Association Study

Correlation of Lipid Profile and Risk of Developing Type 2 Diabetes Mellitus in 10-14 Year Old Children

Habiba, N. M., Fulda, K. G., Basha, R. M., Shah, D., Fernando, S., Nguyen, B., Xiong, Y., Franks, S. F., Matches, S., Magie, R. D. & Bowman, P., 1 Nov 2016, In : Cellular Physiology and Biochemistry. 39, 5, p. 1695-1704 10 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Lipids
Social Class
Logistic Models
Cholesterol
2015
71 Citations (Scopus)

Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: A prospective study

Pui, C. H., Pei, D., Coustan-Smith, E., Jeha, S., Cheng, C., Bowman, W. P., Sandlund, J. T., Ribeiro, R. C., Rubnitz, J. E., Inaba, H., Bhojwani, D., Gruber, T. A., Leung, W. H., Downing, J. R., Evans, W. E., Relling, M. V. & Campana, D., 1 Jan 2015, In : The Lancet Oncology. 16, 4, p. 465-474 10 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Prospective Studies
Remission Induction
Therapeutics
5 Citations (Scopus)

Combination of 13 cis-retinoic acid and tolfenamic acid induces apoptosis and effectively inhibits high-risk neuroblastoma cell proliferation

Shelake, S., Eslin, D., Sutphin, R. M., Sankpal, U. T., Wadwani, A., Kenyon, L. E., Tabor-Simecka, L., Bowman, W. P., Vishwanatha, J. K. & Basha, R., 1 Nov 2015, In : International Journal of Developmental Neuroscience. 46, p. 92-99 8 p.

Research output: Contribution to journalArticle

Isotretinoin
Neuroblastoma
Tretinoin
Cell Proliferation
Apoptosis
32 Citations (Scopus)

Genome-wide analysis links NFATC2 with asparaginase hypersensitivity

Fernandez, C. A., Smith, C., Yang, W., Mullighan, C. G., Qu, C., Larsen, E., Bowman, W. P., Liu, C., Ramsey, L. B., Chang, T., Karol, S. E., Loh, M. L., Raetz, E. A., Winick, N. J., Hunger, S. P., Carroll, W. L., Jeha, S., Pui, C. H., Evans, W. E., Devidas, M. & 1 others, Relling, M. V., 2 Jul 2015, In : Blood. 126, 1, p. 69-75 7 p.

Research output: Contribution to journalArticle

NFATC Transcription Factors
Asparaginase
Hypersensitivity
Genes
Precursor Cell Lymphoblastic Leukemia-Lymphoma
71 Citations (Scopus)

Germline genetic variation in ETV6 and risk of childhood acute lymphoblastic leukaemia: A systematic genetic study

Moriyama, T., Metzger, M. L., Wu, G., Nishii, R., Qian, M., Devidas, M., Yang, W., Cheng, C., Cao, X., Quinn, E., Raimondi, S., Gastier-Foster, J. M., Raetz, E., Larsen, E., Martin, P. L., Bowman, W. P., Winick, N., Komada, Y., Wang, S., Edmonson, M. & 12 others, Xu, H., Mardis, E., Fulton, R., Pui, C. H., Mullighan, C., Evans, W. E., Zhang, J., Hunger, S. P., Relling, M. V., Nichols, K. E., Loh, M. L. & Yang, J. J., 1 Jan 2015, In : The Lancet Oncology. 16, 16, p. 1659-1666 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia
Exome
Charities
Erythroblasts
30 Citations (Scopus)

Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children

Xu, H., Zhang, H., Yang, W., Yadav, R., Morrison, A. C., Qian, M., Devidas, M., Liu, Y., Perez-Andreu, V., Zhao, X., Gastier-Foster, J. M., Lupo, P. J., Neale, G., Raetz, E., Larsen, E., Bowman, W. P., Carroll, W. L., Winick, N., Williams, R., Hansen, T. & 13 others, Holm, J. C., Mardis, E., Fulton, R., Pui, C. H., Zhang, J., Mullighan, C. G., Evans, W. E., Hunger, S. P., Gupta, R., Schmiegelow, K., Loh, M. L., Relling, M. V. & Yang, J. J., 24 Jun 2015, In : Nature Communications. 6, 7553.

Research output: Contribution to journalArticle

leukemias
loci
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tumors
coding
34 Citations (Scopus)

Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels

Mullighan, C. G., Jeha, S., Pei, D., Payne-Turner, D., Coustan-Smith, E., Roberts, K. G., Waanders, E., Choi, J. K., Ma, X., Raimondi, S. C., Fan, Y., Yang, W., Song, G., Yang, J. J., Inaba, H., Downing, J. R., Leung, W. H., Bowman, W. P., Relling, M. V., Evans, W. E. & 3 others, Zhang, J., Campana, D. & Pui, C. H., 24 Dec 2015, In : Blood. 126, 26, p. 2896-2899 4 p.

Research output: Contribution to journalLetter

14 Citations (Scopus)

Prognostic factors in children with acute myeloid leukaemia and excellent response to remission induction therapy

Karol, S. E., Coustan-Smith, E., Cao, X., Shurtleff, S. A., Raimondi, S. C., Choi, J. K., Ribeiro, R. C., Dahl, G. V., Bowman, P., Taub, J. W., Degar, B., Leung, W., Downing, J. R., Pui, C. H., Rubnitz, J. E., Campana, D. & Inaba, H., 1 Jan 2015, In : British Journal of Haematology. 168, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

Remission Induction
Residual Neoplasm
Acute Myeloid Leukemia
Leukemia, Megakaryoblastic, Acute
Therapeutics
23 Citations (Scopus)

Subclinical cardiotoxicity in childhood cancer survivors exposed to very low dose anthracycline therapy

Leger, K., Slone, T., Lemler, M., Leonard, D., Cochran, C., Bowman, P., Bashore, L. & Winick, N., 1 Jan 2015, In : Pediatric Blood and Cancer. 62, 1, p. 123-127 5 p.

Research output: Contribution to journalArticle

Anthracyclines
Survivors
Neoplasms
Therapeutics
Left Ventricular Function
8 Citations (Scopus)

Universal cholesterol screening of children in community-based ambulatory pediatric clinics

Wilson, D. P., Davis, S., Matches, S., Shah, D., Leung-Pineda, V., Mou, M., Hamilton, L., McNeal, C. J. & Bowman, P., 1 Sep 2015, In : Journal of Clinical Lipidology. 9, 5, p. S88-S92 766.

Research output: Contribution to journalArticle

National Heart, Lung, and Blood Institute (U.S.)
Cholesterol
Pediatrics
Publications
Hyperlipoproteinemia Type II
32 Citations (Scopus)

Utility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids

Kaste, S. C., Pei, D., Cheng, C., Neel, M. D., Bowman, P., Ribeiro, R. C., Metzger, M. L., Bhojwani, D., Inaba, H., Campbell, P., Rubnitz, J. E., Jeha, S., Sandlund, J. T., Downing, J. R., Relling, M. V., Pui, C. H. & Howard, S. C., 20 Feb 2015, In : Journal of Clinical Oncology. 33, 6, p. 610-615 6 p.

Research output: Contribution to journalArticle

Osteonecrosis
Glucocorticoids
Hip
Magnetic Resonance Imaging
Pediatrics
2014
62 Citations (Scopus)

A revised definition for cure of childhood acute lymphoblastic leukemia

Pui, C. H., Pei, D., Campana, D., Cheng, C., Sandlund, J. T., Bowman, P., Hudson, M. M., Ribeiro, R. C., Raimondi, S. C., Jeha, S., Howard, S. C., Bhojwani, D., Inaba, H., Rubnitz, J. E., Metzger, M. L., Gruber, T. A., Coustan-Smith, E., Downing, J. R., Leung, W. H., Relling, M. V. & 1 others, Evans, W. E., 11 Dec 2014, In : Leukemia. 28, 12, p. 2336-2343 8 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Therapeutics
Recurrence
Cranial Irradiation
Second Primary Neoplasms
42 Citations (Scopus)

HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies

Fernandez, C. A., Smith, C., Yang, W., Daté, M., Bashford, D., Larsen, E., Bowman, W. P., Liu, C., Ramsey, L. B., Chang, T., Turner, V., Loh, M. L., Raetz, E. A., Winick, N. J., Hunger, S. P., Carroll, W. L., Onengut-Gumuscu, S., Chen, W. M., Concannon, P., Rich, S. S. & 6 others, Scheet, P., Jeha, S., Pui, C. H., Evans, W. E., Devidas, M. & Relling, M. V., 21 Aug 2014, In : Blood. 124, 8, p. 1266-1276 11 p.

Research output: Contribution to journalArticle

Allergies
Asparaginase
HLA Antigens
Hypersensitivity
Alleles
185 Citations (Scopus)

Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's oncology group study AALL0031

Schultz, K. R., Carroll, A., Heerema, N. A., Bowman, P., Aledo, A., Slayton, W. B., Sather, H., Devidas, M., Zheng, H. W., Davies, S. M., Gaynon, P. S., Trigg, M., Rutledge, R., Jorstad, D., Winick, N., Borowitz, M. J., Hunger, S. P., Carroll, W. L. & Camitta, B., 1 Jan 2014, In : Leukemia. 28, 7, p. 1467-1471 5 p.

Research output: Contribution to journalArticle

Philadelphia Chromosome
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Bone Marrow
Pediatrics
Transplants
12 Citations (Scopus)

Philadelphia chromosome-negative very high-risk acute lymphoblastic leukemia in children and adolescents: Results from children's oncology group study AALL0031

Schultz, K. R., Devidas, M., Bowman, P., Aledo, A., Slayton, W. B., Sather, H., Zheng, H. W., Davies, S. M., Gaynon, P. S., Trigg, M., Rutledge, R., Jorstad, D., Carroll, A. J., Heerema, N., Winick, N., Borowitz, M. J., Hunger, S. P., Carroll, W. L. & Camitta, B., 1 Jan 2014, In : Leukemia. 28, 4, p. 964-967 4 p.

Research output: Contribution to journalLetter

Philadelphia Chromosome
Residual Neoplasm
Bone Marrow Transplantation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
12 Citations (Scopus)

Targeted nanoparticles for pediatric leukemia therapy

Basha, R., Sabnis, N., Heym, K., Bowman, W. P. & Lacko, A. G., 1 Jan 2014, In : Frontiers in Oncology. 4 MAY, 101.

Research output: Contribution to journalReview article

Nanoparticles
Leukemia
Pediatrics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Myeloid Leukemia
2013
27 Citations (Scopus)

Gemtuzumab ozogamicin can reduce minimal residual disease in patients with childhood acute myeloid leukemia

O'Hear, C., Inaba, H., Pounds, S., Shi, L., Dahl, G., Bowman, P., Taub, J. W., Pui, C. H., Ribeiro, R. C., Coustan-Smith, E., Campana, D. & Rubnitz, J. E., 15 Nov 2013, In : Cancer. 119, 22, p. 4036-4043 8 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Acute Myeloid Leukemia
Combination Drug Therapy
Pediatrics
Drug Therapy
130 Citations (Scopus)

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

Perez-Andreu, V., Roberts, K. G., Harvey, R. C., Yang, W., Cheng, C., Pei, D., Xu, H., Gastier-Foster, J., Shuyu, E., Lim, J. Y. S., Chen, I. M., Fan, Y., Devidas, M., Borowitz, M. J., Smith, C., Neale, G., Burchard, E. G., Torgerson, D. G., Klussmann, F. A., Villagran, C. R. N. & 18 others, Winick, N. J., Camitta, B. M., Raetz, E., Wood, B., Yue, F., Carroll, W. L., Larsen, E., Bowman, W. P., Loh, M. L., Dean, M., Bhojwani, D., Pui, C. H., Evans, W. E., Relling, M. V., Hunger, S. P., Willman, C. L., Mullighan, C. G. & Yang, J. J., 1 Dec 2013, In : Nature Genetics. 45, 12, p. 1494-1498 5 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Recurrence
Odds Ratio
Philadelphia Chromosome
Gene Rearrangement
120 Citations (Scopus)

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations

Xu, H., Yang, W., Perez-Andreu, V., Devidas, M., Fan, Y., Cheng, C., Pei, D., Scheet, P., Burchard, E. G., Eng, C., Huntsman, S., Torgerson, D. G., Dean, M., Winick, N. J., Martin, P. L., Camitta, B. M., Bowman, W. P., Willman, C. L., Carroll, W. L., Mullighan, C. G. & 7 others, Bhojwani, D., Hunger, S. P., Pui, C. H., Evans, W. E., Relling, M. V., Loh, M. L. & Yang, J. J., 15 May 2013, In : Journal of the National Cancer Institute. 105, 10, p. 733-742 10 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Population
Genome-Wide Association Study
Alleles
Incidence
27 Citations (Scopus)

Pre-clinical evaluation of rHDL encapsulated retinoids for the treatment of neuroblastoma

Sabnis, N., Pratap, S., Akopova, I., Bowman, P. W. & Lacko, A. G., 1 Mar 2013, In : Frontiers in Pediatrics. 1, MAR, 6.

Research output: Contribution to journalArticle

Open Access
Fenretinide
Retinoids
HDL Lipoproteins
Neuroblastoma
Nanoparticles
98 Citations (Scopus)

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: A report from the Children's Oncology Group TARGET Project

Loh, M. L., Zhang, J., Harvey, R. C., Roberts, K., Payne-Turner, D., Kang, H., Wu, G., Chen, X., Becksfort, J., Edmonson, M., Buetow, K. H., Carroll, W. L., Chen, I. M., Wood, B., Borowitz, M. J., Devidas, M., Gerhard, D. S., Bowman, P., Larsen, E., Winick, N. & 6 others, Raetz, E., Smith, M., Downing, J. R., Willman, C. L., Mullighan, C. G. & Hunger, S. P., 17 Jan 2013, In : Blood. 121, 3, p. 485-488 4 p.

Research output: Contribution to journalArticle

Pediatrics
Oncology
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Tyrosine
2012
68 Citations (Scopus)

Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia

Liu, C., Kawedia, J. D., Cheng, C., Pei, D., Fernandez, C. A., Cai, X., Crews, K. R., Kaste, S. C., Panetta, J. C., Bowman, W. P., Jeha, S., Sandlund, J. T., Evans, W. E., Pui, C. H. & Relling, M. V., 1 Nov 2012, In : Leukemia. 26, 11, p. 2303-2309 7 p.

Research output: Contribution to journalArticle

Asparaginase
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Antibodies
Hypersensitivity
Osteonecrosis
112 Citations (Scopus)

Comparative analysis of different approaches to measure treatment response in acute myeloid leukemia

Inaba, H., Coustan-Smith, E., Cao, X., Pounds, S. B., Shurtleff, S. A., Wang, K. Y., Raimondi, S. C., Onciu, M., Jacobsen, J., Ribeiro, R. C., Dahl, G. V., Bowman, W. P., Taub, J. W., Degar, B., Leung, W., Downing, J. R., Pui, C. H., Rubnitz, J. E. & Campana, D., 10 Oct 2012, In : Journal of Clinical Oncology. 30, 29, p. 3625-3632 8 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Acute Myeloid Leukemia
Flow Cytometry
Polymerase Chain Reaction
Therapeutics
51 Citations (Scopus)

Dexamethasone exposure and asparaginase antibodies affect relapse risk in acute lymphoblastic leukemia

Kawedia, J. D., Liu, C., Pei, D., Cheng, C., Fernandez, C. A., Howard, S. C., Campana, D., Panetta, J. C., Bowman, W. P., Evans, W. E., Pui, C. H. & Relling, M. V., 16 Feb 2012, In : Blood. 119, 7, p. 1658-1664 7 p.

Research output: Contribution to journalArticle

Asparaginase
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Dexamethasone
Recurrence
Antibodies
32 Citations (Scopus)

Effect of body mass index on the outcome of children with acute myeloid leukemia

Inaba, H., Surprise, H. C., Pounds, S., Cao, X., Howard, S. C., Ringwald-Smith, K., Buaboonnam, J., Dahl, G., Bowman, P., Taub, J. W., Campana, D., Pui, C. H., Ribeiro, R. C. & Rubnitz, J. E., 1 Dec 2012, In : Cancer. 118, 23, p. 5989-5996 8 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Body Mass Index
Thinness
Weights and Measures
Survival Rate
58 Citations (Scopus)

ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: Improved outcome with contemporary therapy

Bhojwani, D., Pei, D., Sandlund, J. T., Jeha, S., Ribeiro, R. C., Rubnitz, J. E., Raimondi, S. C., Shurtleff, S., Onciu, M., Cheng, C., Coustan-Smith, E., Bowman, P., Howard, S. C., Metzger, M. L., Inaba, H., Leung, W., Evans, W. E., Campana, D., Relling, M. V. & Pui, C. H., 1 Feb 2012, In : Leukemia. 26, 2, p. 265-270 6 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Residual Neoplasm
Disease-Free Survival
Survival
Therapeutics
68 Citations (Scopus)

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

Yang, J. J., Cheng, C., Devidas, M., Cao, X., Campana, D., Yang, W., Fan, Y., Neale, G., Cox, N., Scheet, P., Borowitz, M. J., Winick, N. J., Martin, P. L., Bowman, W. P., Camitta, B., Reaman, G. H., Carroll, W. L., Willman, C. L., Hunger, S. P., Evans, W. E. & 3 others, Pui, C. H., Loh, M. & Relling, M. V., 15 Nov 2012, In : Blood. 120, 20, p. 4197-4204 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Polymorphism
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genes
Recurrence
152 Citations (Scopus)

Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: A Children's Oncology Group Study

Chen, I. M., Harvey, R. C., Mullighan, C. G., Gastier-Foster, J., Wharton, W., Kang, H., Borowitz, M. J., Camitta, B. M., Carroll, A. J., Devidas, M., Pullen, D. J., Payne-Turner, D., Tasian, S. K., Reshmi, S., Cottrell, C. E., Reaman, G. H., Bowman, W. P., Carroll, W. L., Loh, M. L., Winick, N. J. & 2 others, Hunger, S. P. & Willman, C. L., 12 Apr 2012, In : Blood. 119, 15, p. 3512-3522 11 p.

Research output: Contribution to journalArticle

Pediatrics
Oncology
Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Sequence Deletion
25 Citations (Scopus)

Treatment outcome in older patients with childhood acute myeloid leukemia

Rubnitz, J. E., Pounds, S., Cao, X., Jenkins, L., Dahl, G., Bowman, W. P., Taub, J. W., Pui, C. H., Ribeiro, R. C., Campana, D. & Inaba, H., 15 Dec 2012, In : Cancer. 118, 24, p. 6253-6259 7 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Disease-Free Survival
Survival
Poisons
Incidence
2011
161 Citations (Scopus)

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia

Yang, J. J., Cheng, C., Devidas, M., Cao, X., Fan, Y., Campana, D., Yang, W., Neale, G., Cox, N. J., Scheet, P., Borowitz, M. J., Winick, N. J., Martin, P. L., Willman, C. L., Bowman, W. P., Camitta, B. M., Carroll, A., Reaman, G. H., Carroll, W. L., Loh, M. & 4 others, Hunger, S. P., Pui, C. H., Evans, W. E. & Relling, M. V., 1 Mar 2011, In : Nature Genetics. 43, 3, p. 237-241 5 p.

Research output: Contribution to journalReview article

Pharmacogenetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Recurrence
North American Indians
Hispanic Americans
32 Citations (Scopus)

Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: Results of Children's Oncology Group trial P9906

Bowman, W. P., Larsen, E. L., Devidas, M., Linda, S. B., Blach, L., Carroll, A. J., Carroll, W. L., Pullen, D. J., Shuster, J., Willman, C. L., Winick, N., Camitta, B. M., Hunger, S. P. & Borowitz, M. J., 1 Oct 2011, In : Pediatric Blood and Cancer. 57, 4, p. 569-577 9 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Residual Neoplasm
Pediatrics
Bone Marrow
Therapeutics
83 Citations (Scopus)

Improved prognosis for older adolescents with acute lymphoblastic leukemia

Pui, C. H., Pei, D., Campana, D., Bowman, W. P., Sandlund, J. T., Kaste, S. C., Ribeiro, R. C., Rubnitz, J. E., Coustan-Smith, E., Jeha, S., Cheng, C., Metzger, M. L., Bhojwani, D., Inaba, H., Raimondi, S. C., Onciu, M., Howard, S. C., Leung, W., Downing, J. R., Evans, W. E. & 1 others, Relling, M. V., 1 Feb 2011, In : Journal of Clinical Oncology. 29, 4, p. 386-391 6 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Disease-Free Survival
Therapeutics
Survival Rate
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
167 Citations (Scopus)

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: A report from the Children's Oncology Group

Zhang, J., Mullighan, C. G., Harvey, R. C., Wu, G., Chen, X., Edmonson, M., Buetow, K. H., Carroll, W. L., Chen, I. M., Devidas, M., Gerhard, D. S., Loh, M. L., Reaman, G. H., Relling, M. V., Camitta, B. M., Bowman, W. P., Smith, M. A., Willman, C. L., Downing, J. R. & Hunger, S. P., 15 Sep 2011, In : Blood. 118, 11, p. 3080-3087 8 p.

Research output: Contribution to journalArticle

Oncology
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genes
Transcriptome
Gene expression
31 Citations (Scopus)

Shortening infusion time for high-dose methotrexate alters antileukemic effects: A randomized prospective: Clinical trial

Mikkelsen, T. S., Sparreboom, A., Cheng, C., Zhou, Y., Boyett, J. M., Raimondi, S. C., Panetta, J. C., Bowman, W. P., Sandlund, J. T., Pui, C. H., Relling, M. V. & Evans, W. E., 1 May 2011, In : Journal of Clinical Oncology. 29, 13, p. 1771-1778 8 p.

Research output: Contribution to journalArticle

Methotrexate
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Randomized Controlled Trials
Leukemia
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
2010
118 Citations (Scopus)

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia

Kang, H., Chen, I. M., Wilson, C. S., Bedrick, E. J., Harvey, R. C., Atlas, S. R., Devidas, M., Mullighan, C. G., Wang, X., Murphy, M., Ar, K., Wharton, W., Borowitz, M. J., Paul Bowman, W., Bhojwani, D., Carroll, W. L., Camitta, B. M., Reaman, G. H., Smith, M. A., Downing, J. R. & 2 others, Hunger, S. P. & Willman, C. L., 18 Feb 2010, In : Blood. 115, 7, p. 1394-1405 12 p.

Research output: Contribution to journalArticle

Pediatrics
Residual Neoplasm
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Gene expression
Classifiers
238 Citations (Scopus)

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: Correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

Harvey, R. C., Mullighan, C. G., Wang, X., Dobbin, K. K., Davidson, G. S., Bedrick, E. J., Chen, I. M., Atlas, S. R., Kang, H., Ar, K., Wilson, C. S., Wharton, W., Murphy, M., Devidas, M., Carroll, A. J., Borowitz, M. J., Bowman, W. P., Downing, J. R., Relling, M., Yang, J. & 7 others, Bhojwani, D., Carroll, W. L., Camitta, B., Reaman, G. H., Smith, M., Hunger, S. P. & Willman, C. L., 2 Dec 2010, In : Blood. 116, 23, p. 4874-4884 11 p.

Research output: Contribution to journalArticle

Pediatrics
Gene Expression Profiling
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Gene expression
Genes
312 Citations (Scopus)

Minimal residual disease-directed therapy for childhood acute myeloid leukaemia: Results of the AML02 multicentre trial

Rubnitz, J. E., Inaba, H., Dahl, G., Ribeiro, R. C., Bowman, P., Taub, J., Pounds, S., Razzouk, B. I., Lacayo, N. J., Cao, X., Meshinchi, S., Degar, B., Airewele, G., Raimondi, S. C., Onciu, M., Coustan-Smith, E., Downing, J. R., Leung, W., Pui, C. H. & Campana, D., 1 Jun 2010, In : The Lancet Oncology. 11, 6, p. 543-552 10 p.

Research output: Contribution to journalArticle

Residual Neoplasm
Acute Myeloid Leukemia
Multicenter Studies
Therapeutics
Hematopoietic Stem Cell Transplantation
314 Citations (Scopus)

Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia

Harvey, R. C., Mullighan, C. G., Chen, I. M., Wharton, W., Mikhail, F. M., Carroll, A. J., Kang, H., Liu, W., Dobbin, K. K., Smith, M. A., Carroll, W. L., Devidas, M., Bowman, P., Camitta, B. M., Reaman, G. H., Hunger, S. P., Downing, J. R. & Willman, C. L., 1 Jul 2010, In : Blood. 115, 26, p. 5312-5321 10 p.

Research output: Contribution to journalArticle

Janus Kinases
Pediatrics
Cytokine Receptors
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Hispanic Americans