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2018
12 Citations (Scopus)

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies

Martins, R. N., Villemagne, V., Sohrabi, H. R., Chatterjee, P., Shah, T. M., Verdile, G., Fraser, P., Taddei, K., Gupta, V. B., Rainey-Smith, S. R., Hone, E., Pedrini, S., Lim, W. L., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K. & 17 others, Fuller, S. J., Brown, B., Gardener, S. L., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S. M., Barron, A. M., Goozee, K., Wahjoepramono, E. J., Asih, P. R., Doecke, J. D., Salvado, O., Bush, A. I., Rowe, C. C., Gandy, S. E. & Masters, C. L., 1 Jan 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 965-992 28 p.

Research output: Contribution to journalReview article

Amyloid
Alzheimer Disease
Oxidative Stress
Cohort Studies
Biomarkers
3 Citations (Scopus)

A Precision Medicine Model for Targeted NSAID Therapy in Alzheimer's Disease

O'Bryant, S. E., Zhang, F., Johnson, L. A., Hall, J., Edwards, M., Grammas, P., Oh, E., Lyketsos, C. G. & Rissman, R. A., 1 Jan 2018, In : Journal of Alzheimer's disease : JAD. 66, 1, p. 97-104 8 p.

Research output: Contribution to journalArticle

Precision Medicine
Non-Steroidal Anti-Inflammatory Agents
Alzheimer Disease
Naproxen
Proteomics
11 Citations (Scopus)

Association of cerebrospinal fluid α-synuclein with total and phospho-tau181 protein concentrations and brain amyloid load in cognitively normal subjective memory complainers stratified by Alzheimer's disease biomarkers

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), Dec 2018, In : Alzheimer's and Dementia. 14, 12, p. 1623-1631 9 p.

Research output: Contribution to journalArticle

Synucleins
Amyloid
Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
3 Citations (Scopus)

Basal forebrain volume, but not hippocampal volume, is a predictor of global cognitive decline in patients with alzheimer's disease treated with cholinesterase inhibitors

For the Alzheimer's Disease Neuroimaging Initiative & Alzheimer Precision Medicine Initiative (APMI), 14 Aug 2018, In : Frontiers in Neurology. 9, AUG, 642.

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Alzheimer Disease
Hippocampus
Cognition
Cholinergic Agents
5 Citations (Scopus)

Blood-based biomarker screening with agnostic biological definitions for an accurate diagnosis within the dimensional spectrum of neurodegenerative diseases

for the Alzheimer Precision Medicine Initiative (APMI), 1 Jan 2018, Methods in Molecular Biology. Humana Press Inc., p. 139-155 17 p. (Methods in Molecular Biology; vol. 1750).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurodegenerative Diseases
Biomarkers
Primary Health Care
Alzheimer Disease
Precision Medicine
39 Citations (Scopus)

Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic

Hampel, H., O’Bryant, S. E., Molinuevo, J. L., Zetterberg, H., Masters, C. L., Lista, S., Kiddle, S. J., Batrla, R. & Blennow, K., 1 Nov 2018, In : Nature Reviews Neurology. 14, 11, p. 639-652 14 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Biomarkers
Amyloidogenic Proteins
tau Proteins
Precision Medicine
61 Citations (Scopus)

Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry

on Behalf of the Members of the WFSBP Task Force Working on this Topic: Peter Riederer, Carla Gallo, Dimitrios Kapogiannis, Andrea Lopez Mato, Florence Thibaut, 19 May 2018, In : World Journal of Biological Psychiatry. 19, 4, p. 244-328 85 p.

Research output: Contribution to journalReview article

Biological Psychiatry
Advisory Committees
Psychiatry
Cerebrospinal Fluid
Dementia
2 Citations (Scopus)

Characteristics of cognitively normal Mexican-Americans with cognitive complaints

Hall, J. R., Wiechmann, A., Johnson, L. A., Edwards, M. & O'Bryant, S. E., 1 Jan 2018, In : Journal of Alzheimer's Disease. 61, 4, p. 1485-1492 8 p.

Research output: Contribution to journalArticle

Affective Symptoms
Research
Proteomics
Cognition
Population
40 Citations (Scopus)

Current state of Alzheimer’s fluid biomarkers

Molinuevo, J. L., Ayton, S., Batrla, R., Bednar, M. M., Bittner, T., Cummings, J., Fagan, A. M., Hampel, H., Mielke, M. M., Mikulskis, A., O’Bryant, S., Scheltens, P., Sevigny, J., Shaw, L. M., Soares, H. D., Tong, G., Trojanowski, J. Q., Zetterberg, H. & Blennow, K., 1 Jan 2018, (Accepted/In press) In : Acta Neuropathologica.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Patient Selection
Cerebrospinal Fluid
Neurogranin
Neuropsychological Tests
Language
Hispanic Americans
Statistical Factor Analysis
chemotactic factor inactivator

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, 1 Jan 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticle

Cholesterol Ester Transfer Proteins
HDL Cholesterol
Alzheimer Disease
Genes
Single Nucleotide Polymorphism

Inflammatory biomarkers, depressive symptoms and falls among the elderly in panama

Britton, G. B., O’bryant, S. E., Johnson, L. A., Hall, J. R., Villarreal, A. E., Oviedo, D. C., Pérez-Lao, A. R. & Carreira, M. B., 1 Jan 2018, In : Current Aging Science. 11, 4, p. 236-241 6 p.

Research output: Contribution to journalArticle

Open Access
Panama
Interleukin-7
Biomarkers
Depression
Activities of Daily Living
4 Citations (Scopus)

Odorant Item Specific Olfactory Identification Deficit May Differentiate Alzheimer Disease From Aging

Texas Alzheimer's Research, Care Consortium, Aug 2018, In : American Journal of Geriatric Psychiatry. 26, 8, p. 835-846 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Smell
Odorants
Healthy Volunteers
Biomarkers
12 Citations (Scopus)

Sex differences in functional and molecular neuroimaging biomarkers of Alzheimer's disease in cognitively normal older adults with subjective memory complaints

INSIGHT-preAD Study Group & the Alzheimer Precision Medicine Initiative (APMI), Sep 2018, In : Alzheimer's and Dementia. 14, 9, p. 1204-1215 12 p.

Research output: Contribution to journalReview article

Functional Neuroimaging
Sex Characteristics
Alzheimer Disease
Biomarkers
Gyrus Cinguli
29 Citations (Scopus)

Sex-specific association of apolipoprotein e with cerebrospinal fluid levels of tau

Alzheimer's Disease Genetics Consortium and the Alzheimer's Disease Neuroimaging Initiative, 1 Aug 2018, In : JAMA Neurology. 75, 8, p. 989-998 10 p.

Research output: Contribution to journalArticle

Apolipoproteins
Apolipoproteins E
Cerebrospinal Fluid
Alzheimer Disease
Neurofibrillary Tangles
14 Citations (Scopus)

Sex-specific genetic predictors of Alzheimer’s disease biomarkers

Alzheimer’S Disease Neuroimaging Initiative (Adni) & The Alzheimer Disease Genetics Consortium (Adgc), 1 Dec 2018, In : Acta Neuropathologica. 136, 6, p. 857-872 16 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Biomarkers
Genome-Wide Association Study
Amyloid
Endophenotypes
2 Citations (Scopus)
Hispanic Americans
Education
Research
6 Citations (Scopus)
Trail Making Test
Reproduction
Education
Population

The Link between Potassium and Mild Cognitive Impairment in Mexican-Americans

Vintimilla, R. M., Large, S. E., Gamboa, A., Rohlfing, G. D., O'Jile, J. R., Hall, J. R., O'Bryant, S. E. & Johnson, L. A., 1 Jan 2018, In : Dementia and Geriatric Cognitive Disorders Extra. 8, 1, p. 151-157 7 p.

Research output: Contribution to journalArticle

Potassium
Hispanic Americans
Serum
Urban Health
Education
2017
5 Citations (Scopus)

A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of β-amyloid load in an AD cohort

Pedrini, S., Gupta, V. B., Hone, E., Doecke, J., O'Bryant, S., James, I., Bush, A. I., Rowe, C. C., Villemagne, V. L., Ames, D., Masters, C. L., Martins, R. N., Savage, G., Wilson, B., Bourgeat, P., Fripp, J., Gibson, S., Leroux, H., McBride, S., Salvado, O. & 92 others, Fenech, M., Francois, M., Barnes, M., Baker, J., Barnham, K., Bellingham, S., Bomke, J., Pejoska, S. B., Buckley, R., Cheng, L., Collins, S., Cooke, I., Cyarto, E., Darby, D., Dore, V., El-Sheikh, D., Faux, N., Fowler, C., Harrington, K., Hill, A., Horne, M., Jones, G., Kamer, A., Killeen, N., Korrel, H., Lamb, F., Lautenschlager, N., Lennon, K., Li, Q. X., Lim, Y. Y., Louey, A., Macaulay, L., Mackintosh, L., Maruff, P., McIlroy, A., Nigro, J., Perez, K., Pertile, K., Restrepo, C., Cardoso, B. R., Rembach, A., Roberts, B., Robertson, J., Rumble, R., Ryan, T., Sach, J., Silbert, B., Thai, C., Trounson, B., Volitakis, I., Vovos, M., Ward, L., Watt, A., Williams, R., Woodward, M., Yates, P., Ugarte, F. Y., Zhang, P., Bird, S., Brown, B., Burnham, S., Chatterjee, P., Cox, K., Fernandez, S., Fernando, B., Gardener, S., Laws, S., Lim, F., Lim, L., Tegg, M., Lucas, K., Martins, G., Porter, T., Rainey-Smith, S., Rodrigues, M., Shen, K., Sohrabi, H., Taddei, K., Taddei, T., Tan, S., Verdile, G., Weinborn, M., Farrow, M., Frost, S., Hanson, D., Hor, M., Kanagasingam, Y., Leifert, W., Lockett, L., Riley, M., Saunders, I. & Thomas, P., 1 Dec 2017, In : Scientific Reports. 7, 1, 14057.

Research output: Contribution to journalArticle

Interleukin-12
Amyloid
Interleukin-10
Alzheimer Disease
Biomarkers
6 Citations (Scopus)
Longitudinal Studies
Life Style
Blood Proteins
Alzheimer Disease
Cohort Studies
48 Citations (Scopus)

A Precision Medicine Initiative for Alzheimer’s disease: the road ahead to biomarker-guided integrative disease modeling

for the Alzheimer Precision Medicine Initiative, 4 Mar 2017, In : Climacteric. 20, 2, p. 107-118 12 p.

Research output: Contribution to journalReview article

Precision Medicine
Alzheimer Disease
Biomarkers
Magic
Systems Biology

Blood and cerebrospinal fluid biomarkers for Alzheimer’s disease

Lista, S., Zetterberg, H., O’Bryant, S. E., Blennow, K. & Hampel, H., 1 Jan 2017, Dementia, Fifth Edition. CRC Press, p. 528-538 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cerebrospinal Fluid
Alzheimer Disease
Biomarkers
National Institute on Aging (U.S.)
Biological Phenomena
90 Citations (Scopus)

Blood-based biomarkers in Alzheimer disease: Current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

Biofluid Based Biomarker Professional Interest Area, 1 Jan 2017, In : Alzheimer's and Dementia. 13, 1, p. 45-58 14 p.

Research output: Contribution to journalShort survey

Alzheimer Disease
Biomarkers
Public-Private Sector Partnerships
Research
Neurodegenerative Diseases
3 Citations (Scopus)

Depression, inflammation, and memory loss among Mexican Americans: Analysis of the HABLE cohort

Johnson, L. A., Edwards, M., Gamboa, A., Hall, J., Robinson, M. & O'Bryant, S. E., 1 Oct 2017, In : International Psychogeriatrics. 29, 10, p. 1693-1699 7 p.

Research output: Contribution to journalArticle

Memory Disorders
Endophenotypes
Hispanic Americans
Depression
Inflammation
6 Citations (Scopus)

Evolving relevance of neuroproteomics in Alzheimer’s disease

Lista, S., Zetterberg, H., O’Bryant, S. E., Blennow, K. & Hampel, H., 1 Jan 2017, Methods in Molecular Biology. Humana Press Inc., p. 101-115 15 p. (Methods in Molecular Biology; vol. 1598).

Research output: Chapter in Book/Report/Conference proceedingChapter

Alzheimer Disease
Systems Biology
Biomarkers
Early Diagnosis
Mass Spectrometry
204 Citations (Scopus)

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Uitterlinden, A. G., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., 1 Sep 2017, In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Gene Frequency
Alzheimer Disease
Odds Ratio
Microglia
34 Citations (Scopus)

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Alzheimer's Disease Genetics Consortium, Jul 2017, In : Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome
Single Nucleotide Polymorphism
Genome-Wide Association Study
Apolipoprotein E4
7 Citations (Scopus)

Water T2 as an early, global and practical biomarker for metabolic syndrome: An observational cross-sectional study

Robinson, M. D., Mishra, I., Deodhar, S., Patel, V., Gordon, K. V., Vintimilla, R., Brown, K., Johnson, L., O'Bryant, S. & Cistola, D. P., 19 Dec 2017, In : Journal of Translational Medicine. 15, 1, 258.

Research output: Contribution to journalArticle

Biomarkers
Cross-Sectional Studies
Water
Medical problems
Plasmas
2016
18 Citations (Scopus)

A blood screening test for Alzheimer's disease

O'Bryant, S. E., Edwards, M., Johnson, L., Hall, J., Villarreal, A. E., Britton, G. B., Quiceno, M., Cullum, C. M. & Graff-Radford, N. R., 1 Jan 2016, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 3, p. 83-90 8 p.

Research output: Contribution to journalArticle

Hematologic Tests
Alzheimer Disease
Neurodegenerative Diseases
Primary Health Care
Population

A depressive endophenotype for predicting cognitive decline among mexican American adults and elders

Johnson, L. A., Gamboa, A., Vintimilla, R., Edwards, M., Hall, J., Weiser, B., Yadav, M., Dickensheets, T. & O'Bryant, S., 23 Aug 2016, In : Journal of Alzheimer's Disease. 54, 1, p. 201-206 6 p.

Research output: Contribution to journalArticle

Endophenotypes
Cognition
Short-Term Memory
Analysis of Variance
Alzheimer Disease
1 Citation (Scopus)

An Empirical Comparison of Competing Factor Structures for the Repeatable Battery for the Assessment of Neuropsychological Status: A Project FRONTIER Study

Torrence, N. D., John, S. E., Gavett, B. E. & O'Bryant, S., 1 Feb 2016, In : Archives of Clinical Neuropsychology. 31, 1, p. 88-96 9 p.

Research output: Contribution to journalArticle

Rural Health
Statistical Factor Analysis
Epidemiologic Studies
Education
chemotactic factor inactivator
80 Citations (Scopus)

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 332 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., 1 Jan 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons
20 Citations (Scopus)

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), 1 May 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells
2 Citations (Scopus)

Characterization of Alzheimer's Disease and Mild Cognitive Impairment in Older Adults in Panama

Villarreal, A. E., Grajales, S., O'Bryant, S. E., Edwards, M., López, L., Montalván, A. & Britton, G. B., 1 Jan 2016, In : Journal of Alzheimer's Disease. 54, 3, p. 897-901 5 p.

Research output: Contribution to journalArticle

Panama
Alzheimer Disease
Apolipoprotein E4
Central America
Genetic Testing
23 Citations (Scopus)

Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges

for the ISTAART Blood Based Biomarker Professional Interest Area, 1 Jan 2016, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 3, p. 27-34 8 p.

Research output: Contribution to journalArticle

Malus
Alzheimer Disease
Biomarkers
Fatty Acid-Binding Proteins
Interleukin-18
3 Citations (Scopus)

IL-7 and Depression: The importance of gender and blood fraction

Hall, J. R., Wiechmann, A., Edwards, M., Johnson, L. A. & O'Bryant, S. E., 15 Dec 2016, In : Behavioural Brain Research. 315, p. 147-149 3 p.

Research output: Contribution to journalArticle

Interleukin-7
Depression
Alzheimer Disease
Serum
Logistic Models
5 Citations (Scopus)
Alzheimer Disease
Biomarkers
405 Citations (Scopus)

Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

Proceedings of the Meeting of the International Working Group (IWG) and the American Alzheimer's Association on "The Preclinical State of AD"; July 23, 2015; Washington DC, USA, 1 Mar 2016, In : Alzheimer's and Dementia. 12, 3, p. 292-323 32 p.

Research output: Contribution to journalReview article

Natural History
Alzheimer Disease
Asymptomatic Diseases
Research
Biomarkers
10 Citations (Scopus)

Serum-based protein profiles of Alzheimer's disease and mild cognitive impairment in elderly Hispanics

Panama Aging Research Initiative, 1 Jun 2016, In : Neurodegenerative disease management. 6, 3, p. 203-213 11 p.

Research output: Contribution to journalArticle

Hispanic Americans
Blood Proteins
Alzheimer Disease
Biomarkers
Apolipoprotein E4
1 Citation (Scopus)

Vitamin C supplementation, APOE4 genotype and cognitive functioning in a rural-dwelling cohort

Chaudhari, K., Sumien, N., Johnson, L., D’Agostino, D., Edwards, M., Paxton, R. J., Hall, J. R. & O’Bryant, S. E., 1 Oct 2016, In : Journal of Nutrition, Health and Aging. 20, 8, p. 841-844 4 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Cognition
Ascorbic Acid
Genotype
Rural Population
2015
8 Citations (Scopus)
Endophenotypes
Independent Living
Western Australia
Cognition
Depression
4 Citations (Scopus)

An item response theory analysis of the Executive Interview and development of the EXIT8: A project FRONTIER study

Jahn, D. R., Dressel, J. A., Gavett, B. E. & O'Bryant, S. E., 16 Mar 2015, In : Journal of Clinical and Experimental Neuropsychology. 37, 3, p. 229-242 14 p.

Research output: Contribution to journalArticle

Word Association Tests
Interviews
Trail Making Test
Rural Health
Psychometrics
10 Citations (Scopus)

Association between cognitive impairment and chronic kidney disease in Mexican Americans

Szerlip, H. M., Edwards, M. L., Williams, B. J., Johnson, L. A., Vintimilla, R. M. & O'Bryant, S. E., Oct 2015, In : Journal of the American Geriatrics Society. 63, 10, p. 2023-2028 6 p.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Chronic Renal Insufficiency
Proteomics
Odds Ratio
Repression (Psychology)
41 Citations (Scopus)

Biomarkers in Sporadic and Familial Alzheimer's Disease

Lista, S., O'Bryant, S., Blennow, K., Dubois, B., Hugon, J., Zetterberg, H. & Hampel, H., 24 Jul 2015, In : Journal of Alzheimer's Disease. 47, 2, p. 291-317 27 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Biomarkers
Systems Biology
Metabolomics
Genome-Wide Association Study
6 Citations (Scopus)

Can genetic analysis of putative blood Alzheimer's disease biomarkers lead to identification of susceptibility loci?

Barber, R. C., Phillips, N. R., Tilson, J. L., Huebinger, R. M., Shewale, S. J., Koenig, J. L., Mitchel, J. S., O'Bryant, S. E., Waring, S. C., Diaz-Arrastia, R., Chasse, S. & Wilhelmsen, K. C., 1 Dec 2015, In : PLoS ONE. 10, 12, e0142360.

Research output: Contribution to journalArticle

Hematologic Diseases
Biomarkers
Alzheimer disease
Endophenotypes
genetic techniques and protocols
20 Citations (Scopus)

Comorbid Depression and Diabetes as a Risk for Mild Cognitive Impairment and Alzheimer's Disease in Elderly Mexican Americans

Johnson, L. A., Gamboa, A., Vintimilla, R., Cheatwood, A. J., Grant, A., Trivedi, A., Edwards, M., Hall, J. & O'Bryant, S., 1 Jan 2015, In : Journal of Alzheimer's Disease. 47, 1, p. 129-136 8 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Depression
Odds Ratio
Comorbidity
Cognitive Dysfunction
21 Citations (Scopus)

Evolving Evidence for the Value of Neuroimaging Methods and Biological Markers in Subjects Categorized with Subjective Cognitive Decline

Lista, S., Molinuevo, J. L., Cavedo, E., Rami, L., Amouyel, P., Teipel, S. J., Garaci, F., Toschi, N., Habert, M. O., Blennow, K., Zetterberg, H., O'Bryant, S., Johnson, L. A., Galluzzi, S., Bokde, A. L. W., Broich, K., Herholz, K., Bakardjian, H., Dubois, B., Jessen, F. & 3 others, Carrillo, M. C., Aisen, P. S. & Hampel, H., 24 Sep 2015, In : Journal of Alzheimer's Disease. 48, S1, p. S171-S191

Research output: Contribution to journalReview article

Neuroimaging
Biomarkers
Alzheimer Disease
Cognitive Dysfunction
Neurophysiology
87 Citations (Scopus)

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

O'Bryant, S. E., Gupta, V., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C., Soares, H., Lovestone, S., Hampel, H., Montine, T., Blennow, K., Foroud, T., Carrillo, M., Graff-Radford, N., Laske, C., Breteler, M., Shaw, L., Trojanowski, J. Q., Schupf, N. & 8 others, Rissman, R. A., Fagan, A. M., Oberoi, P., Umek, R., Weiner, M. W., Grammas, P., Posner, H. & Martins, R., 1 May 2015, In : Alzheimer's and Dementia. 11, 5, p. 549-560 12 p.

Research output: Contribution to journalReview article

Alzheimer Disease
Biomarkers
Guidelines
Research
Neuroimaging
97 Citations (Scopus)

Innovative diagnostic tools for early detection of Alzheimer's disease

Laske, C., Sohrabi, H. R., Frost, S. M., López-De-Ipiña, K., Garrard, P., Buscema, M., Dauwels, J., Soekadar, S. R., Mueller, S., Linnemann, C., Bridenbaugh, S. A., Kanagasingam, Y., Martins, R. N. & O'bryant, S. E., 1 May 2015, In : Alzheimer's and Dementia. 11, 5, p. 561-578 18 p.

Research output: Contribution to journalReview article

Early Diagnosis
Alzheimer Disease
Hematologic Tests
Neuroimaging
Cerebrospinal Fluid