Find Research Outputs

2019
1 Citation (Scopus)

Brain delivery of thyrotropin-releasing hormone via a novel prodrug approach

Prokai-Tatrai, K., De La Cruz, D. L., Nguyen, V., Ross, B. P., Toth, I. & Prokai, L., Jul 2019, In : Pharmaceutics. 11, 7, 349.

Research output: Contribution to journalArticle

Open Access
Thyrotropin-Releasing Hormone
Prodrugs
prolyl oligopeptidase
Brain
Peptides
1 Citation (Scopus)

Breakthroughs in medicinal chemistry: New targets and mechanisms, New Drugs, New Hopes-5

Mangoni, A. A., Eynde, J. J. V., Jampilek, J., Hadjipavlou-Litina, D., Liu, H., Reynisson, J., Sousa, M. E., Gomes, P. A. C., Prokai-Tatrai, K., Tuccinardi, T., Sabatier, J. M., Luque, F. J., Rautio, J., Karaman, R., Vasconcelos, M. H., Gemma, S., Galdiero, S., Hulme, C., Collina, S., Gütschow, M. & 6 others, Kokotos, G., Siciliano, C., Capasso, R., Agrofoglio, L. A., Ragno, R. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 13, 2415.

Research output: Contribution to journalReview article

Open Access
Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations

Breakthroughs in medicinal chemistry: New targets and mechanisms, new drugs, new hopes-4

Mangoni, A. A., Guillou, C., Eynde, J. J. V., Hulme, C., Jampilek, J., Li, W., Prokai-Tatrai, K., Rautio, J., Collina, S., Tuccinardi, T., Sousa, M. E., Sabatier, J. M., Galdiero, S., Karaman, R., Kokotos, G., Torri, G., Javier Luque, F., Helena Vasconcelos, M., Hadjipavlou-Litina, D., Siciliano, C. & 5 others, Gütschow, M., Ragno, R., Gomes, P. A. C., Agrofoglio, L. A. & Muñoz-Torrero, D., 1 Jan 2019, In : Molecules. 24, 1, p. 1-12 12 p.

Research output: Contribution to journalReview article

Pharmaceutical Chemistry
drugs
chemistry
Pharmaceutical Preparations
1 Citation (Scopus)

Cancer survivors' experiences with breakdowns in patient-centered communication

Street, R. L., Spears, E. C., Madrid, S. & Mazor, K. M., 1 Feb 2019, In : Psycho-Oncology. 28, 2, p. 423-429 7 p.

Research output: Contribution to journalArticle

Survivors
Communication
Neoplasms
Delivery of Health Care
Foster Home Care
5 Citations (Scopus)

Cannabinoid-like effects of five novel carboxamide synthetic cannabinoids

Gatch, M. B. & Forster, M. J., 1 Jan 2019, In : NeuroToxicology. 70, p. 72-79 8 p.

Research output: Contribution to journalArticle

Dronabinol
Cannabinoids
Locomotion
Drug Legislation
Cannabis

Cardiac structure and function in well-healed burn survivors

Samuel, T. J., Nelson, M. D., Nasirian, A., Jaffery, M., Moralez, G., Romero, S. A., Cramer, M. N., Huang, M., Kouda, K., Hieda, M., Sarma, S. & Crandall, C. G., 20 Feb 2019, In : Journal of Burn Care and Research. 40, 2, p. 235-241 7 p.

Research output: Contribution to journalArticle

Open Access
Survivors
Ventricular Remodeling
Exercise
Left Ventricular Function
Wounds and Injuries
1 Citation (Scopus)
Motor Skills Disorders
Pressure
Autism Spectrum Disorder
Motor Skills
Child Development

Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.

Research output: Contribution to journalArticle

Astrocytes
Oxidative Stress
Neuroprotective Agents
Energy Metabolism
Glutamic Acid

Chronic inhibition of mitochondrial dihydrolipoamide dehydrogenase (DLDH) as an approach to managing diabetic oxidative stress

Yang, X., Song, J. & Yan, L. J., 1 Jan 2019, In : Antioxidants. 8, 2, 32.

Research output: Contribution to journalArticle

Open Access
Dihydrolipoamide Dehydrogenase
Oxidative stress
Oxidative Stress
Medical problems
Type 2 Diabetes Mellitus

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

Silzer, T., Barber, R., Sun, J., Pathak, G., Johnson, L., O’Bryant, S. & Phillips, N., Mar 2019, In : PLoS ONE. 14, 3, e0213527.

Research output: Contribution to journalArticle

Open Access
Mexican Americans
Medical problems
Mitochondrial DNA
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus

Climatic adaptation in human inferior nasal turbinate morphology: Evidence from Arctic and equatorial populations

Marks, T. N., Maddux, S. D., Butaric, L. N. & Franciscus, R. G., 1 Jul 2019, In : American Journal of Physical Anthropology. 169, 3, p. 498-512 15 p.

Research output: Contribution to journalArticle

Turbinates
Arctic
Nose
Population
evidence
1 Citation (Scopus)

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, P., Simecka, J., Raut, S. L., Ray, A. & Basha, R. M., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticle

Ewing's Sarcoma
Vincristine
Cells
Caspase 7
Cell Survival

Cognitive training and transcranial direct current stimulation in mild cognitive impairment: A randomized pilot trial

Das, N., Spence, J. S., Aslan, S., Vanneste, S., Mudar, R., Rackley, A., Quiceno, M. & Chapman, S. B., 1 Jan 2019, In : Frontiers in Neuroscience. 13, APR, 307.

Research output: Contribution to journalArticle

Open Access
Cerebrovascular Circulation
Executive Function
Episodic Memory
Cognitive Dysfunction
Transcranial Direct Current Stimulation

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, W. P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticle

Medulloblastoma
Vincristine
tolfenamic acid
Cell Cycle
Apoptosis

Commentaries on health services research

Smith, B. J., Hooker, R. S., McMichael, B. J., Salsberg, E. & Forister, J. G., 1 Jan 2019, In : JAAPA : official journal of the American Academy of Physician Assistants. 32, 1, p. 54-56 3 p.

Research output: Contribution to journalArticle

Health Services Research
1 Citation (Scopus)

Comparison of diabetic nephropathy between male and female eNOS-/- db/db mice

Ma, Y., Li, W., Shotorbani, P. Y., Dubansky, B. H., Huang, L., Chaudhari, S., Wu, P., Wang, L. A., Ryou, M. G., Zhou, Z. & Ma, R., May 2019, In : American Journal of Physiology - Renal Physiology. 316, 5, p. F889-F897

Research output: Contribution to journalArticle

Diabetic Nephropathies
Sex Characteristics
Kidney
Physiological Phenomena
Albuminuria
1 Citation (Scopus)

Compound stutter in D2S1338 and D12S391

Woerner, A. E., King, J. L. & Budowle, B., 1 Mar 2019, In : Forensic Science International: Genetics. 39, p. 50-56 7 p.

Research output: Contribution to journalArticle

Linear Models
Nucleotides
High-Throughput Nucleotide Sequencing
3 Citations (Scopus)

Considerations in addressing the opioid epidemic and chronic pain within the USA

Marshall, B., Bland, M. K., Hulla, R. & Gatchel, R. J., 1 Mar 2019, In : Pain management. 9, 2, p. 131-138 8 p.

Research output: Contribution to journalArticle

Chronic Pain
Opioid Analgesics
Neurobiology
Pain Management
Therapeutics
1 Citation (Scopus)

Copan microFLOQ® Direct Swab collection of bloodstains, saliva, and semen on cotton cloth

Sherier, A. J., Kieser, R. E., Novroski, N. M. M., Wendt, F. R., King, J. L., Woerner, A. E., Ambers, A., Garofano, P. & Budowle, B., 1 Jan 2019, In : International journal of legal medicine.

Research output: Contribution to journalArticle

Semen
Saliva
Coloring Agents
Polymerase Chain Reaction
Blood Stains
2 Citations (Scopus)

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R. M., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Copper
Neoplasms
Powders
tolfenamic acid
Cell Line
Open Access
Retinal Ganglion Cells
Glaucoma
Publications
Cell Death
Animal Models
Open Access
National Institute of Neurological Disorders and Stroke
Organized Financing
Astrocytes
Histones
Methylation
Opioid Analgesics
Prescriptions
Logistic Models
North American Indians
Cannabis
2 Citations (Scopus)

Dental opinion leaders’ perspectives on barriers and facilitators to HPV-related prevention

Griner, S. B., Thompson, E. L., Vamos, C. A., Chaturvedi, A. K., Vazquez-Otero, C., Merrell, L. K., Kline, N. S. & Daley, E. M., 3 Aug 2019, In : Human Vaccines and Immunotherapeutics. 15, 7-8, p. 1856-1862 7 p.

Research output: Contribution to journalArticle

Tooth
Oropharyngeal Neoplasms
Dental Research
Education
Papillomavirus Vaccines

Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D3 receptor ligands

Chen, P. J., Taylor, M., Griffin, S. A., Amani, A., Hayatshahi, H., Korzekwa, K., Ye, M., Mach, R. H., Liu, J., Luedtke, R. R., Gordon, J. C. & Blass, B. E., 15 Sep 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 18, p. 2690-2694 5 p.

Research output: Contribution to journalArticle

Benzamides
Dopamine D3 Receptors
Pharmacokinetics
Dopamine Receptors
Substance-Related Disorders
2 Citations (Scopus)

Development and Validation of an Algorithm to Classify as Equivalent the Procedures in ICD-10-PCS That Differ only by Laterality

Epstein, R. H., Dexter, F. & O'Neill, L., 1 Jun 2019, In : Anesthesia and analgesia. 128, 6, p. 1138-1144 7 p.

Research output: Contribution to journalArticle

International Classification of Diseases
Inpatients
Language
Operative Surgical Procedures
Confidence Intervals

Development of a motivational interviewing genetic counseling intervention to increase cascade cholesterol screening in families of children with familial hypercholesterolemia

Kruger, V., Redlinger-Grosse, K., Walters, S. T., Ash, E., Cragun, D., McCarthy Veach, P. & Zierhut, H. A., 1 Oct 2019, In : Journal of Genetic Counseling. 28, 5, p. 1059-1064 6 p.

Research output: Contribution to journalArticle

Motivational Interviewing
Hyperlipoproteinemia Type II
Genetic Engineering
Health Behavior
Genetic Counseling

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), 1 Jul 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticle

Apolipoprotein E4
Amyloid
Alzheimer Disease
Brain
Frontal Lobe
1 Citation (Scopus)

Differential effects of protein kinase C-eta on apoptosis versus senescence

Basu, A., Pal, D. & Blaydes, R., 1 Mar 2019, In : Cellular Signalling. 55, p. 1-7 7 p.

Research output: Contribution to journalArticle

Apoptosis
Doxorubicin
Breast Neoplasms
protein kinase C eta
Galactosidases

Different reactivity to glutathione but similar tumor cell toxicity of chalcones and their quinolinone analogues

d’Oliveira, G. D. C., Custodio, J. M. F., Moura, A. F., Napolitano, H. B., Pérez, C. N., Moraes, M. O., Prókai, L. & Perjési, P., 1 Sep 2019, In : Medicinal Chemistry Research. 28, 9, p. 1448-1460 13 p.

Research output: Contribution to journalArticle

Open Access
Chalcones
Chalcone
Quinolones
Glutathione
Toxicity

Direct Oral Anticoagulants in Chronic Liver Disease

Steuber, T. D., Howard, M. & Nisly, S. A., 1 Oct 2019, In : Annals of Pharmacotherapy. 53, 10, p. 1042-1049 8 p.

Research output: Contribution to journalReview article

Anticoagulants
Liver Diseases
Chronic Disease
Clinical Trials
Information Storage and Retrieval

Discovery of 4-alkoxy-6-methylpicolinamide negative allosteric modulators of metabotropic glutamate receptor subtype 5

Felts, A. S., Bollinger, K. A., Brassard, C. J., Rodriguez, A. L., Morrison, R. D., Scott Daniels, J., Blobaum, A. L., Niswender, C. M., Jones, C. K., Jeffrey Conn, P., Emmitte, K. A. & Lindsley, C. W., 1 Jan 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 47-50 4 p.

Research output: Contribution to journalArticle

Aldehyde Oxidase
Metabotropic Glutamate 5 Receptor
Metabotropic Glutamate Receptors
Metabolism
Modulators
1 Citation (Scopus)

Discovery of Novel Central Nervous System Penetrant Metabotropic Glutamate Receptor Subtype 2 (mGlu 2 ) Negative Allosteric Modulators (NAMs) Based on Functionalized Pyrazolo[1,5- a]pyrimidine-5-carboxamide and Thieno[3,2- b]pyridine-5-carboxamide Cores

Childress, E. S., Wieting, J. M., Felts, A. S., Breiner, M. M., Long, M. F., Luscombe, V. B., Rodriguez, A. L., Cho, H. P., Blobaum, A. L., Niswender, C. M., Emmitte, K. A., Conn, P. J. & Lindsley, C. W., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 378-384 7 p.

Research output: Contribution to journalArticle

Rodentia
Central Nervous System
pyridine
pyrazolo(1,5-a)pyrimidine
metabotropic glutamate receptor 2
1 Citation (Scopus)

Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M 1 Positive Allosteric Modulators

Engers, J. L., Bender, A. M., Kalbfleisch, J. J., Cho, H. P., Lingenfelter, K. S., Luscombe, V. B., Han, C., Melancon, B. J., Blobaum, A. L., Dickerson, J. W., Rook, J. M., Niswender, C. M., Emmitte, K. A., Conn, P. J. & Lindsley, C. W., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1035-1042 8 p.

Research output: Contribution to journalArticle

Lactams
Modulators
Cell Line
Muscarinic Receptors
Cells
5 Citations (Scopus)

Discovery of VU2957 (Valiglurax): An mGlu 4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease

Panarese, J. D., Engers, D. W., Wu, Y. J., Bronson, J. J., Macor, J. E., Chun, A., Rodriguez, A. L., Felts, A. S., Engers, J. L., Loch, M. T., Emmitte, K. A., Castelhano, A. L., Kates, M. J., Nader, M. A., Jones, C. K., Blobaum, A. L., Conn, P. J., Niswender, C. M., Hopkins, C. R. & Lindsley, C. W., 14 Mar 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 255-260 6 p.

Research output: Contribution to journalArticle

Pulse amplitude modulation
Toxicology
Modulators
Parkinson Disease
Pharmacology

Diversity in the era of precision medicine - From bench to bedside implementation

Mamun, A., Nsiah, N. Y., Srinivasan, M., Chaturvedula, A., Basha, R., Cross, D., Jones, H. P., Nandy, K. & Vishwanatha, J. K., 1 Jan 2019, In : Ethnicity and Disease. 29, 3, p. 517-524 8 p.

Research output: Contribution to journalArticle

Precision Medicine
Health
Pharmacogenetics
Genomics
Population
Osteopathic Manipulation
Fourth Ventricle
Premature Obstetric Labor
Pregnancy
Research

Does Current General Mental Health Status Relate to Current Smoking Status in Pregnant Women?

Liu, D., Younger, E., Baker, S., Touch, S., Willmoth, T. & Hartos, J. L., 1 Jan 2019, In : Journal of Pregnancy. 2019, 7801465.

Research output: Contribution to journalArticle

Open Access
Health Status
Pregnant Women
Mental Health
Smoking
Tobacco Use
3 Citations (Scopus)

Doing it for the money: The relationship between gambling and money attitudes among college students

Lostutter, T. W., Enkema, M., Schwebel, F., Cronce, J. M., Garberson, L. A., Ou, B., Lewis, M. A. & Larimer, M. E., 1 Jan 2019, In : Journal of gambling studies. 35, 1, p. 143-153 11 p.

Research output: Contribution to journalArticle

Gambling
gambling
money
Students
student

Do physical activity levels differ by number of children at home in women aged 25–44 in the general population?

Abell, L. P., Tanase, K. A., Gilmore, M. L., Winnicki, A. E., Holmes, V. L. & Hartos, J. L., 1 Jan 2019, In : Women's Health. 15

Research output: Contribution to journalArticle

Open Access
Exercise
Population
Odds Ratio
Confidence Intervals
Behavioral Risk Factor Surveillance System

Drug Enforcement Administration Rescheduling of Hydrocodone Combination Products Is Associated With Changes in Physician Pain Management Prescribing Preferences

Fleming, M. L., Driver, L., Sansgiry, S. S., Abughosh, S. M., Wanat, M. A., Varisco, T. J., Pickard, T., Reeve, K. & Todd, K. H., 3 Apr 2019, In : Journal of Pain and Palliative Care Pharmacotherapy. 33, 1-2, p. 22-31 10 p.

Research output: Contribution to journalArticle

Hydrocodone
Pain Management
Physicians
Drug Administration Schedule
Pharmaceutical Preparations

Drugs in tuberculosis and leprosy

Ramanathan, M. R., Howell, C. K. & Sanders, J. M., 2019, Side Effects of Drugs Annual. Ray, S. D. (ed.). Elsevier B.V., p. 321-338 18 p. (Side Effects of Drugs Annual; vol. 41).

Research output: Chapter in Book/Report/Conference proceedingChapter

Linezolid
bedaquiline
Rifamycins
Thioacetazone
Aminosalicylic Acid

Early career biomedical grantsmanship self-efficacy: validation of an abbreviated self-assessment tool

Harwood, E. M., Jones, A. R., Erickson, D., Buchwald, D., Johnson-Hemming, J., Jones, H. P., Manson, S., McGee, R., Smith, A., Steer, C. J., Vishwanatha, J. K., Weber-Main, A. M. & Okuyemi, K. S., Jun 2019, In : Annals of the New York Academy of Sciences. 1445, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Self Efficacy
Organized Financing
Research Personnel
Research
Equipment and Supplies

Effect of coverage gap on healthcare utilization among Medicare beneficiaries with chronic obstructive pulmonary disorder

Sansgiry, S. S., Bhansali, A., Serna, O., Kamdar, M., Fleming, M. L., Abughosh, S. & Stanford, R. H., 1 Feb 2019, In : Current Medical Research and Opinion. 35, 2, p. 321-328 8 p.

Research output: Contribution to journalArticle

Medicare
Hospitalization
Delivery of Health Care
Lung
Chronic Obstructive Pulmonary Disease

Effect of Intermittent Hypoxia Training for Dizziness: A Randomized Controlled Trial

Bao, X., Tan, J. W., Long, Y., Liu, H. & Liu, H. Y., 1 Aug 2019, In : Journal of sport rehabilitation. 28, 6, p. 540-543 4 p.

Research output: Contribution to journalArticle

Dizziness
Randomized Controlled Trials
Vertigo
Visual Analog Scale
Equipment and Supplies

Effect of ocular hypertension on the pattern of retinal ganglion cell subtype loss in a mouse model of early-onset glaucoma

Daniel, S., Meyer, K. J., Clark, A., Anderson, M. G. & McDowell, C. M., 1 Aug 2019, In : Experimental eye research. 185, 107703.

Research output: Contribution to journalArticle

Ocular Hypertension
Retinal Ganglion Cells
Glaucoma
Intraocular Pressure
Phenotype

Effect of Sociodemographic Factors on Uptake of a Patient-Facing Information Technology Family Health History Risk Assessment Platform

Wu, R. R., Myers, R. A., Buchanan, A. H., Dimmock, D., Fulda, K. G., Haller, I. V., Haga, S. B., Harry, M. L., McCarty, C., Neuner, J., Rakhra-Burris, T., Sperber, N., Voils, C. I., Ginsburg, G. S. & Orlando, L. A., 1 Jan 2019, In : Applied Clinical Informatics. 10, 2, p. 180-188 9 p.

Research output: Contribution to journalArticle

Medical History Taking
Facings
Risk assessment
Information technology
Health

Effects of dietary 5-methoxyindole-2-carboxylic acid on brain functional recovery after ischemic stroke

Sumien, N., Huang, R., Chen, Z., Vann, P. H., Wong, J. M., Li, W., Yang, S., Forster, M. J. & Yan, L. J., 1 Jan 2019, (Accepted/In press) In : Behavioural Brain Research. 112278.

Research output: Contribution to journalArticle

Stroke
Long-Term Potentiation
Brain
Cognition
Wounds and Injuries

Effects of elastic band exercise on the frailty states in pre-frail elderly people

Chen, R., Wu, Q., Wang, D., Li, Z., Liu, H., Liu, G., Cui, Y. & Song, L., 1 Jan 2019, In : Physiotherapy Theory and Practice.

Research output: Contribution to journalArticle

Frail Elderly
Exercise
Hand Strength
Control Groups
Randomized Controlled Trials

Effects of exercise training on the autophagy-related muscular proteins expression in ovariectomized rats

Zhong, W., Shi, X., Yuan, H., Bu, H., Wu, L. & Wang, R., 1 Jan 2019, In : Frontiers in Physiology. 10, JUN, 735.

Research output: Contribution to journalArticle

Open Access
Exercise
Autophagy
Ovariectomy
Skeletal Muscle
Microtubule-Associated Proteins