Find Research Outputs

Search concepts
Selected Filters
36 Citations (Scopus)

Neuroprotection targeting ischemic penumbra and beyond for the treatment of ischemic stroke

Liu, R., Yuan, H., Yuan, F. & Yang, S., 1 Jun 2012, In : Neurological Research. 34, 4, p. 331-337 7 p.

Research output: Contribution to journalReview article

Stroke
Therapeutics
Vascular Dementia
Neuroprotection
Cellular Structures
80 Citations (Scopus)

Neuroprotective Actions of Methylene Blue and Its Derivatives

Poteet, E., Winters, A., Yan, L-J., Shufelt, K., Green, K. N., Simpkins, J. W., Wen, Y. & Yang, S., 31 Oct 2012, In : PLoS ONE. 7, 10, e48279.

Research output: Contribution to journalArticle

neuroprotective effect
methylene blue
Methylene Blue
chemical derivatives
Derivatives
17 Citations (Scopus)

Neuroprotective effects of high affinity sigma 1 receptor selective compounds

Luedtke, R. T., Perez, E., Yang, S., Liu, R., Vangveravong, S., Tu, Z., MacH, R. H. & Simpkins, J. W., 2 Mar 2012, In : Brain Research. 1441, p. 17-26 10 p.

Research output: Contribution to journalArticle

Neuroprotective Agents
Haloperidol
Stroke
sigma Receptors
Pentazocine
37 Citations (Scopus)

PRDM1 is directly targeted by miR-30a-5p and modulates the Wnt/β-catenin pathway in a Dkk1-dependent manner during glioma growth

Wang, X., Wang, K., Han, L., Zhang, A., Shi, Z., Zhang, K., Zhang, H., Yang, S., Pu, P., Shen, C., Yu, C. & Kang, C., 1 May 2013, In : Cancer Letters. 331, 2, p. 211-219 9 p.

Research output: Contribution to journalArticle

Catenins
Wnt Signaling Pathway
Glioma
Growth
Computational Biology
1 Citation (Scopus)

Precision Medicine for Ischemic Stroke, Let Us Move Beyond Time Is Brain

Yang, S., Lou, M., Luo, B., Jiang, W. J. & Liu, R., 1 Apr 2018, In : Translational Stroke Research. 9, 2, p. 93-95 3 p.

Research output: Contribution to journalEditorial

Precision Medicine
Stroke
Brain
13 Citations (Scopus)

PTEN degradation after ischemic stroke: A double-edged sword

Li, W., Huang, R-Q., Chen, Z., Yan, L-J., Simpkins, J. W. & Yang, S., 22 Aug 2014, In : Neuroscience. 274, p. 153-161 9 p.

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Stroke
GABA-A Receptors
Brain Ischemia
Astrocytes
8 Citations (Scopus)

Pyruvate minimizes rtPA toxicity from in vitro oxygen-glucose deprivation and reoxygenation

Ryou, M. G., Choudhury, G. R., Winters, A., Xie, L., Mallet, R. T. & Yang, S., 12 Sep 2013, In : Brain Research. 1530, p. 66-75 10 p.

Research output: Contribution to journalArticle

Tissue Plasminogen Activator
Pyruvic Acid
Oxygen
Glucose
NADP
54 Citations (Scopus)

Pyruvate protects the brain against ischemia-reperfusion injury by activating the erythropoietin signaling pathway

Ryou, M. G., Liu, R., Ren, M., Sun, J., Mallet, R. T. & Yang, S., 1 Apr 2012, In : Stroke. 43, 4, p. 1101-1107 7 p.

Research output: Contribution to journalArticle

Erythropoietin
Reperfusion Injury
Brain Ischemia
Pyruvic Acid
Hypoxia-Inducible Factor 1
53 Citations (Scopus)

Reactive oxygen species-mediated TRPC6 protein activation in vascular myocytes, a mechanism for vasoconstrictor-regulated vascular tone

Ding, Y., Winters, A., Ding, M., Graham, S., Akopova, I., Muallem, S., Wang, Y., Hong, J. H., Gryczynski, Z., Yang, S., Birnbaumer, L. & Ma, R., 9 Sep 2011, In : Journal of Biological Chemistry. 286, 36, p. 31799-31809 11 p.

Research output: Contribution to journalArticle

Vasoconstrictor Agents
Vascular Smooth Muscle
Knockout Mice
Muscle Cells
Smooth Muscle Myocytes
28 Citations (Scopus)

Regulation of matrix metalloproteinase 2 by oligomeric amyloid β protein

Li, W., Poteet, E., Xie, L., Liu, R., Wen, Y. & Yang, S., 28 Apr 2011, In : Brain Research. 1387, p. 141-148 8 p.

Research output: Contribution to journalArticle

Amyloidogenic Proteins
Matrix Metalloproteinase 2
Matrix Metalloproteinases
Astrocytes
Alzheimer Disease
39 Citations (Scopus)

Reversing the Warburg effect as a treatment for glioblastoma

Poteet, E., Choudhury, G. R., Winters, A., Li, W., Ryou, M. G., Liu, R., Tang, L., Ghorpade, A., Wen, Y., Yuan, F., Keir, S. T., Yan, H., Bigner, D. D., Simpkins, J. W. & Yang, S., 29 Mar 2013, In : Journal of Biological Chemistry. 288, 13, p. 9153-9164 12 p.

Research output: Contribution to journalArticle

Methylene Blue
Glioblastoma
Cell proliferation
Energy Metabolism
AMP-Activated Protein Kinases
1 Citation (Scopus)

Silencing AQP4 gene in the astrocytes through siRNA transfection by lipofectamine RNAiMAX

Zhang, W., Xu, L. X., Yang, S., Shi, Z. F., Dong, L. P. & Yuan, F., 1 Jan 2014, In : Acta Anatomica Sinica. 45, 2, p. 161-165 5 p.

Research output: Contribution to journalArticle

Gene Silencing
Astrocytes
Small Interfering RNA
Transfection
Real-Time Polymerase Chain Reaction
29 Citations (Scopus)

Stress induces p38 MAPK-mediated phosphorylation and inhibition of drosha-dependent cell survival

Yang, Q., Li, W., She, H., Dou, J., Duong, D. M., Du, Y., Yang, S., Seyfried, N. T., Fu, H., Gao, G. & Mao, Z., 19 Feb 2015, In : Molecular Cell. 57, 4, p. 721-734 14 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
MicroRNAs
Cell Survival
Phosphorylation
Ribonuclease III

Surgical management of giant intrapetrous internal carotid aneurysm presenting with coil exposure after endovascular treatment

Yu, L. B., Zhang, D., Yang, S. & Zhao, J. Z., 1 Jul 2018, In : Neurosurgical Review. 41, 3, p. 891-894 4 p.

Research output: Contribution to journalArticle

Aneurysm
Otoscopes
Therapeutics
Digital Subtraction Angiography
Referral and Consultation
21 Citations (Scopus)

The assessment of non-feminizing estrogens for use in neuroprotection

Yi, K. D., Perez, E., Yang, S., Liu, R., Covey, D. F. & Simpkins, J. W., 16 Mar 2011, In : Brain Research. 1379, p. 61-70 10 p.

Research output: Contribution to journalReview article

Estrogens
Estrogen Receptor alpha
Steroids
Research
Women's Health
15 Citations (Scopus)

Transient Focal Cerebral Ischemia Induces Long-term Cerebral Vasculature Dysfunction in a Rodent Experimental Stroke Model

Winters, A., Taylor, J. C., Ren, M., Ma, R., Liu, R. & Yang, S., 1 Jun 2012, In : Translational Stroke Research. 3, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Rodentia
Theoretical Models
Stroke
Phenylephrine
41 Citations (Scopus)

Transient focal cerebral ischemia induces long-term cognitive function deficit in an experimental ischemic stroke model

Li, W., Huang, R-Q., Shetty, R. A., Thangthaeng, N., Liu, R., Chen, Z., Sumien, N., Rutledge, M., Dillon, G. H., Yuan, F., Forster, M. J., Simpkins, J. W. & Yang, S., 1 Nov 2013, In : Neurobiology of Disease. 59, p. 18-25 8 p.

Research output: Contribution to journalArticle

Transient Ischemic Attack
Cognition
Long-Term Potentiation
Stroke
Hippocampus
12 Citations (Scopus)

Upregulation of miR-20a and miR-106b is involved in the acquisition of malignancy of pediatric brainstem gliomas

Wang, X., Zhang, H., Zhang, A., Han, L., Wang, K., Liu, R., Yang, S., Pu, P., Shen, C., Kang, C. & Yu, C., 1 Oct 2012, In : Oncology Reports. 28, 4, p. 1293-1300 8 p.

Research output: Contribution to journalArticle

Glioma
Brain Stem
Up-Regulation
Pediatrics
MicroRNAs
25 Citations (Scopus)

Window of opportunity: Estrogen as a treatment for ischemic stroke

Liu, R. & Yang, S., 13 Jun 2013, In : Brain Research. 1514, p. 83-90 8 p.

Research output: Contribution to journalReview article

Estrogens
Stroke
Estrogen Replacement Therapy
Clinical Trials
Therapeutics