Keyphrases
Estradiol
100%
Male Depression
100%
Male Mice
100%
Antidepressants
75%
Anxiolytic Activity
75%
Depression Treatment
75%
Specific Intent
75%
Animal Model of Depression
50%
Animal Models of Anxiety
50%
Behavioral Outcomes
50%
Bioactivation
25%
Limited Consideration
25%
Female Rodents
25%
Orchidectomy
25%
Deleterious Effects
25%
Innovative Compounds
25%
Acute Administration
25%
Human Subject Test
25%
Feminization
25%
Inappropriate Treatment
25%
Male Human
25%
Signaling Pathway Activity
25%
CNS Disorders
25%
Potential Side Effects
25%
Chronic Administration
25%
Peripheral Tissues
25%
Human Males
25%
Rodents
25%
Non-target
25%
Aromatase
25%
Bioanalytical Methods
25%
Beneficial Effects
25%
Depressive-like Behavior
25%
Intracellular Signaling
25%
Clinical Treatment
25%
Dose-response Curve
25%
Treatment Study
25%
17β-estradiol
25%
Successful Completion
25%
Dose-response Study
25%
Brain Levels
25%
Systemic Administration
25%
Anxiety-like Behavior
25%
Female Mice
25%
Potential Treatments
25%
Unique Mechanism
25%
Unmet Needs
25%
Bioprecursor Prodrug
25%
Signaling Pathway
25%
Male Brain
25%
Mechanism of Action
25%
Male Behavior
25%
Estrogen Receptor
25%
Testosterone
25%
Brain Concentration
25%
Neuroscience
Behavior (Neuroscience)
100%
Diethylstilbestrol
100%
Treatment of Depression
100%
Antidepressant
100%
Cell Signaling
66%
Estrogen Receptor
33%
Aromatase
33%
Intracellular Signaling
33%
Prodrug
33%
Pharmacology, Toxicology and Pharmaceutical Science
Diethylstilbestrol
100%
Antidepressant
100%
Aromatase
33%
Central Nervous System Disease
33%
Boron 10
33%
Prodrug
33%
Systemic Administration
33%
Feminization
33%
Preclinical Study
33%
Estrogen Receptor
33%
Side Effect
33%
Bioactivation
33%
17b-Estradiol
33%