Keyphrases
Genome Editing
100%
Primary Open-angle Glaucoma
100%
Glaucoma Treatment
100%
Glaucoma
85%
Myocilin Gene
71%
Endoplasmic Reticulum Stress (ER stress)
57%
Myocilin
57%
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
42%
Trabecular Meshwork
42%
Mouse Model
42%
Nuclease
28%
Disease Mechanisms
28%
Underlying Disease
28%
Gene-gene
28%
Organ Culture System
14%
Gene Therapy
14%
Novel Treatments
14%
Risk Factors
14%
Gain-of-function mutation
14%
Pathway Genes
14%
Human Eye
14%
Vision Loss
14%
Steroid-induced Glaucoma
14%
Organ System
14%
Gene mutation
14%
Blindness
14%
Current Treatment
14%
Endoplasmic Reticulum
14%
Genetic Causes
14%
Editing Strategies
14%
Stress-responsive Genes
14%
Eye Disorders
14%
Endoplasmic Reticulum Stress-induced Apoptosis
14%
RNA Sequencing (RNA-seq)
14%
Apoptotic Pathway
14%
Trabecular Meshwork Cells
14%
Therapeutic Potential
14%
Genome-editing nucleases
14%
Perfusion
14%
Intraocular Pressure
14%
Biochemistry, Genetics and Molecular Biology
Endoplasmic Reticulum Stress
100%
Genome Editing
100%
Cas9
80%
CRISPR
60%
Mouse Model
60%
Nuclease
60%
Genetics
40%
Genome Editing
40%
Programmed Cell Death
40%
RNA Sequence
20%
Gene Mutation
20%
Intraocular Pressure
20%
Gain of Function Mutation
20%
Gene Therapy
20%
Perfusion
20%
Organ Culture
20%
Pharmacology, Toxicology and Pharmaceutical Science
Glaucoma
100%
Myocilin
81%
Open Angle Glaucoma
63%
Mouse Model
27%
Elimination
27%
Nuclease
27%
Diseases
27%
Eye Disease
9%
Visual Impairment
9%