Discovery of small molecule activators of the Slack potassium channel for use as cell-based probes for the study of fragile X syndrome

Medicine & Life Sciences

1. Fragile X Syndrome 100%
2. Fragile X Mental Retardation Protein 94%
3. Ion Channels 76%
4. Intellectual Disability 43%
5. Potassium Channels 35%
6. Pharmaceutical Chemistry 21%
7. Structure-Activity Relationship 18%
8. Critical Pathways 17%
9. RNA-Binding Proteins 17%
10. Electrophysiology 17%
11. HEK293 Cells 16%
12. Gene Silencing 16%
13. Autism Spectrum Disorder 15%
14. Solubility 15%
15. Membrane Potentials 15%
16. Permeability 13%
17. Ions 12%
18. Cognition 12%
19. Cell Membrane 11%
20. Water 10%
21. Therapeutics 10%
22. Neurons 9%
23. Drug Therapy 9%
24. Animals 7%
25. Pharmaceutical Preparations 6%