• Lacko, Andras (PI)
  • Harris, Ben Gerald (PI)
  • Harris, Ben Gerald (PI)

Project Details


We are requesting for funds to purchase an oligonucleotide synthesizer, a
peptide synthesizer with a dedicated HPLC system and an automated DNA
sequencing system. The instruments will be housed at The School of
Veterinary Medicine and supervised by a committee of major users from six
different Department of The School of Veterinary Medicine, The School of
Medicine and The School of Arts and Sciences all located within a one to
two block area of the campus. The major users consist of 21 different
groups (146 research personnel) with over 38 federal and non-federal grants
who will use these instruments for 80% of the time. The research interests
of the major user group are focused on the basic as well as the applied
aspects of cell and molecular biology, including transgenic research,
development aspects of histone and immunoglobin gene expression, gene
expression during embryogenesis and cell differentiation, cell-cell
interaction, membrane biogenesis, mitochondrial and nuclear gene
interaction, herpesviral gene expression and development of vaccines,
structure and function of ion-channels, signal transduction in neural
cells, diseases of the neuromuscular and hemetopoetic systems, and
characterization of genetic disorders of inherited metabolic diseases and
development of gene therapy in various animal models. All of these
projects involve extensive use of DNA sequencing and synthetic peptide and
oligonucleotide probes.
Effective start/end date31/12/8929/09/94


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