• 2030 Citations
  • 23 h-Index
20022022
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Personal profile

Area of Expertise

The research focus in my lab is primarily at the interface of stem cell and cancer biology. We use systems biology approaches to understand how gene expression, protein posttranslational modifications, and signaling networks are regulated in normal and pathological development of human cells. With the knowledge from our study, we also work on the identification of novel targets and the development of new therapeutic approaches for human disease, including cancer and neurodevelopmental disorders, by modulating the novel targets.

Education/Academic qualification

PhD in Medicinal Chemistry, Ohio State University

BS in Biology, National Taiwan Normal University

Fingerprint Dive into the research topics where Yu-Chieh Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Pluripotent Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Celecoxib Medicine & Life Sciences
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
Histone Deacetylase Inhibitors Medicine & Life Sciences
troglitazone Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences
Tumor Suppressor Protein p14ARF Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2022

Research Output 2002 2019

  • 2030 Citations
  • 23 h-Index
  • 30 Article
  • 4 Review article
  • 1 Chapter
  • 1 Letter

Wearable Devices for Single-Cell Sensing and Transfection

Chang, L., Wang, Y-C., Ershad, F., Yang, R., Yu, C. & Fan, Y., 1 Jan 2019, In : Trends in Biotechnology.

Research output: Contribution to journalReview articleResearchpeer-review

Transfection
Equipment and Supplies
Molecules
Genetic Selection
Insulin

Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1

Zolekar, A., Lin, V. J. T., Mishra, N. M., Ho, Y. Y., Hayatshahi, H. S., Parab, A., Sampat, R., Liao, X., Hoffmann, P., Liu, J., Emmitte, K. A. & Wang, Y-C., 11 Dec 2018, In : British Journal of Cancer. 119, 12, p. 1538-1551 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Interferons
Melanoma
Apoptosis
Neoplasms
Systems Biology
5 Citations (Scopus)

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

O’Brien, C. M., Chy, H. S., Zhou, Q., Blumenfeld, S., Lambshead, J. W., Liu, X., Kie, J., Capaldo, B. D., Chung, T. L., Adams, T. E., Phan, T., Bentley, J. D., McKinstry, W. J., Oliva, K., McMurrick, P. J., Wang, Y-C., Rossello, F. J., Lindeman, G. J., Chen, D., Jarde, T. & 7 others, Clark, A. T., Abud, H. E., Visvader, J. E., Nefzger, C. M., Polo, J. M., Loring, J. F. & Laslett, A. L., 1 Mar 2017, In : Stem Cells. 35, 3, p. 626-640 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Pluripotent Stem Cells
Membrane Proteins
Monoclonal Antibodies
Epitopes
Cell Culture Techniques
4 Citations (Scopus)

Potassium as a pluripotency-associated element identified through inorganic element profiling in human pluripotent stem cells

Lin, V. J. T., Zolekar, A., Shi, Y., Koneru, B., Dimitrijevich, S., Di Pasqua, A. J. & Wang, Y-C., 1 Dec 2017, In : Scientific Reports. 7, 1, 5005.

Research output: Contribution to journalArticleResearchpeer-review

Pluripotent Stem Cells
Potassium
Cell Membrane Permeability
X-Ray Emission Spectrometry
Cell Physiological Phenomena
27 Citations (Scopus)

Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells

Wang, Y-C., Stein, J. W., Lynch, C. L., Tran, H. T., Lee, C. Y., Coleman, R., Hatch, A., Antontsev, V. G., Chy, H. S., O'Brien, C. M., Murthy, S. K., Laslett, A. L., Peterson, S. E. & Loring, J. F., 25 Aug 2015, In : Scientific Reports. 5, 13317.

Research output: Contribution to journalArticleResearchpeer-review

Glycosyltransferases
Pluripotent Stem Cells
Sialyltransferases
Galactosides
Induced Pluripotent Stem Cells