• 2201 Citations
  • 23 h-Index

Research output per year

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Personal profile

Area of Expertise

The research focus in my lab is primarily at the interface of stem cell and cancer biology. We use systems biology approaches to understand how gene expression, protein posttranslational modifications, and signaling networks are regulated in normal and pathological development of human cells. With the knowledge from our study, we also work on the identification of novel targets and the development of new therapeutic approaches for human disease, including cancer and neurodevelopmental disorders, by modulating the novel targets.

Education/Academic qualification

PhD in Medicinal Chemistry, Ohio State University

Award Date: 1 Jan 2008

BS in Biology, National Taiwan Normal University

Award Date: 1 Jan 2002

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Research Output

  • 2201 Citations
  • 23 h-Index
  • 31 Article
  • 4 Review article
  • 1 Chapter
  • 1 Letter

Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain

Zuo, Z., Zolekar, A., Babu, K., Lin, V. J. T., Hayatshahi, H. S., Rajan, R., Wang, Y. C. & Liu, J., Jul 2019, In : eLife. 8, e46500.

Research output: Contribution to journalArticle

Open Access
  • 1 Scopus citations

    Wearable Devices for Single-Cell Sensing and Transfection

    Chang, L., Wang, Y. C., Ershad, F., Yang, R., Yu, C. & Fan, Y., Nov 2019, In : Trends in Biotechnology. 37, 11, p. 1175-1188 14 p.

    Research output: Contribution to journalReview article

  • 3 Scopus citations

    Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1

    Zolekar, A., Lin, V. J. T., Mishra, N. M., Ho, Y. Y., Hayatshahi, H. S., Parab, A., Sampat, R., Liao, X., Hoffmann, P., Liu, J., Emmitte, K. A. & Wang, Y. C., 11 Dec 2018, In : British Journal of Cancer. 119, 12, p. 1538-1551 14 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

    O’Brien, C. M., Chy, H. S., Zhou, Q., Blumenfeld, S., Lambshead, J. W., Liu, X., Kie, J., Capaldo, B. D., Chung, T. L., Adams, T. E., Phan, T., Bentley, J. D., McKinstry, W. J., Oliva, K., McMurrick, P. J., Wang, Y. C., Rossello, F. J., Lindeman, G. J., Chen, D., Jarde, T. & 7 others, Clark, A. T., Abud, H. E., Visvader, J. E., Nefzger, C. M., Polo, J. M., Loring, J. F. & Laslett, A. L., 1 Mar 2017, In : Stem Cells. 35, 3, p. 626-640 15 p.

    Research output: Contribution to journalArticle

  • 8 Scopus citations

    Potassium as a pluripotency-associated element identified through inorganic element profiling in human pluripotent stem cells

    Lin, V. J. T., Zolekar, A., Shi, Y., Koneru, B., Dimitrijevich, S., Di Pasqua, A. J. & Wang, Y. C., 1 Dec 2017, In : Scientific Reports. 7, 1, 5005.

    Research output: Contribution to journalArticle

  • 6 Scopus citations