• 2167 Citations
  • 23 h-Index
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Area of Expertise

The research focus in my lab is primarily at the interface of stem cell and cancer biology. We use systems biology approaches to understand how gene expression, protein posttranslational modifications, and signaling networks are regulated in normal and pathological development of human cells. With the knowledge from our study, we also work on the identification of novel targets and the development of new therapeutic approaches for human disease, including cancer and neurodevelopmental disorders, by modulating the novel targets.

Education/Academic qualification

PhD in Medicinal Chemistry, Ohio State University

BS in Biology, National Taiwan Normal University

Fingerprint Dive into the research topics where Yu-Chieh Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Pluripotent Stem Cells Medicine & Life Sciences
Stem cells Chemical Compounds
Celecoxib Medicine & Life Sciences
Induced Pluripotent Stem Cells Medicine & Life Sciences
Peroxisome Proliferator-Activated Receptors Medicine & Life Sciences
Histone Deacetylase Inhibitors Medicine & Life Sciences
troglitazone Medicine & Life Sciences
Non-Small Cell Lung Carcinoma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2014 2022

Research Output 2002 2019

  • 2167 Citations
  • 23 h-Index
  • 31 Article
  • 4 Review article
  • 1 Chapter
  • 1 Letter

Structural and functional insights into the bona fide catalytic state of Streptococcus pyogenes Cas9 HNH nuclease domain

Zuo, Z., Zolekar, A., Babu, K., Lin, V. J. T., Hayatshahi, H. S., Rajan, R., Wang, Y. C. & Liu, J., Jul 2019, In : eLife. 8, e46500.

Research output: Contribution to journalArticle

Open Access
Guide RNA
DNA Cleavage
Streptococcus pyogenes
Clustered Regularly Interspaced Short Palindromic Repeats
3 Citations (Scopus)

Wearable Devices for Single-Cell Sensing and Transfection

Chang, L., Wang, Y. C., Ershad, F., Yang, R., Yu, C. & Fan, Y., Nov 2019, In : Trends in Biotechnology. 37, 11, p. 1175-1188 14 p.

Research output: Contribution to journalReview article

Equipment and Supplies
Genetic Selection
2 Citations (Scopus)

Stress and interferon signalling-mediated apoptosis contributes to pleiotropic anticancer responses induced by targeting NGLY1

Zolekar, A., Lin, V. J. T., Mishra, N. M., Ho, Y. Y., Hayatshahi, H. S., Parab, A., Sampat, R., Liao, X., Hoffmann, P., Liu, J., Emmitte, K. A. & Wang, Y-C., 11 Dec 2018, In : British Journal of Cancer. 119, 12, p. 1538-1551 14 p.

Research output: Contribution to journalArticle

Systems Biology
8 Citations (Scopus)

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

O’Brien, C. M., Chy, H. S., Zhou, Q., Blumenfeld, S., Lambshead, J. W., Liu, X., Kie, J., Capaldo, B. D., Chung, T. L., Adams, T. E., Phan, T., Bentley, J. D., McKinstry, W. J., Oliva, K., McMurrick, P. J., Wang, Y. C., Rossello, F. J., Lindeman, G. J., Chen, D., Jarde, T. & 7 others, Clark, A. T., Abud, H. E., Visvader, J. E., Nefzger, C. M., Polo, J. M., Loring, J. F. & Laslett, A. L., 1 Mar 2017, In : Stem Cells. 35, 3, p. 626-640 15 p.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Membrane Proteins
Monoclonal Antibodies
Cell Culture Techniques
6 Citations (Scopus)

Potassium as a pluripotency-associated element identified through inorganic element profiling in human pluripotent stem cells

Lin, V. J. T., Zolekar, A., Shi, Y., Koneru, B., Dimitrijevich, S., Di Pasqua, A. J. & Wang, Y-C., 1 Dec 2017, In : Scientific Reports. 7, 1, 5005.

Research output: Contribution to journalArticle

Pluripotent Stem Cells
Cell Membrane Permeability
X-Ray Emission Spectrometry
Cell Physiological Phenomena