• 1949 Citations
  • 25 h-Index
19982019
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Area of Expertise

The main focus of my research is to discover and develop bioactive natural products from microorganisms as drugs or drug leads for the treatment of cancer, infectious diseases, or other human medical conditions. In addition, I recently initiated a collaborative project for the engineering of novel oncolytic virus for cancer chemoimmunotherapy.
Key words: anti-aging, anti-cancer, anti-infective, crowd-sourcing, crowd-funding, drug discovery, drug development, natural product, synthetic biology, chemoimmunotherapy, contract service

Education/Academic qualification

PhD in Botany & Microbiology, Michigan State University

MS in Phytochemistry, Institute of Botany of the Chinese Academy of Sciences

BS in Microbiology, Huazhong Agricultural University

Fingerprint Dive into the research topics where Yiqiang (Eric) Cheng is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Histone Deacetylase Inhibitors Medicine & Life Sciences
Multigene Family Medicine & Life Sciences
Polyketide Synthases Medicine & Life Sciences
Burkholderia Medicine & Life Sciences
Peptide Synthases Medicine & Life Sciences
Biosynthesis Chemical Compounds
Genes Chemical Compounds
Streptomyces Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2018

Research Output 1998 2019

Origin and bioactivities of thiosulfinated FK228

Liu, X., Currens, G. C., Xue, L. & Cheng, Y., 1 Jan 2019, In : MedChemComm. 10, 4, p. 538-542 5 p.

Research output: Contribution to journalArticle

Bioactivity
Silica Gel
Burkholderia
Histone Deacetylases
romidepsin

Overexpression of somatostatin receptor type 2 in neuroendocrine tumors for improved Ga68-DOTATATE imaging and treatment

Guenter, R., Aweda, T., Carmona Matos, D. M., Jang, S., Whitt, J., Cheng, Y. Q., Liu, X. M., Chen, H., Lapi, S. E. & Jaskula-Sztul, R., 1 Jan 2019, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

Neuroendocrine Tumors
Histone Deacetylase Inhibitors
Neuroendocrine Cells
Therapeutics
Tumor Cell Line

Pulmonary carcinoid surface receptor modulation using histone deacetylase inhibitors

Guenter, R. E., Aweda, T., Matos, D. M. C., Whitt, J., Chang, A. W., Cheng, E. Y., Liu, X. M., Chen, H., Lapi, S. E. & Jaskula-Sztul, R., Jun 2019, In : Cancers. 11, 6, 767.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
Carcinoid Tumor
Lung
Somatostatin
Positron-Emission Tomography

The ADEP biosynthetic gene cluster in Streptomyces hawaiiensis NRRL 15010 reveals an accessory clpP gene as a novel antibiotic resistance factor

Thomy, D., Culp, E., Adamek, M., Cheng, E. Y., Ziemert, N., Wright, G. D., Sass, P. & Brötz-Oesterhelt, H., 1 Jan 2019, In : Applied and Environmental Microbiology. 85, 20, e01292-19.

Research output: Contribution to journalArticle

antibiotic resistance
R Factors
Streptomyces
Multigene Family
Microbial Drug Resistance
1 Citation (Scopus)

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin

Saraiva, R. G., Huitt-Roehl, C. R., Tripathi, A., Cheng, Y. Q., Bosch, J., Townsend, C. A. & Dimopoulos, G., 1 Dec 2018, In : Scientific Reports. 8, 1, 6176.

Research output: Contribution to journalArticle

Chromobacterium
histone deacetylase
Plasmodium
secretion
antimalarials