Projects per year
Personal profile
Area of Expertise
Dr. Dong’s research interests include pharmaceutical analysis/bioanalysis, drug formulation, and delivery. She develops novel formulation nanotechnologies to improve bioavailability of oral drugs and deliver macromolecules such as siRNAs and proteins. In addition to novel drug formulations, her lab evaluates these formulations for therapeutic efficacy (e.g. anticancer drugs), pharmacokinetics, and biodistribution. Thus, her lab has the capacity to perform bioassays for both small molecules and macromolecules. Additionally, she collaborates with the clinical pharmacy to test stability of compounding medications and Y-site compatibility.
Education/Academic qualification
PhD in Pharmaceutical Sciences, University of Kentucky
MS in Applied Chemistry, East China University of Science and Technology
BS in Industrial Analysis
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- 4 Similar Profiles
Nanoparticles
Medicine & Life Sciences
Multiple Drug Resistance
Medicine & Life Sciences
Lipids
Medicine & Life Sciences
Ritonavir
Medicine & Life Sciences
docetaxel
Medicine & Life Sciences
Nerve Growth Factor
Medicine & Life Sciences
HDL Lipoproteins
Medicine & Life Sciences
Paclitaxel
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2014 2016
- 2 Finished
Nanoparticle Drug Delivery to Overcome Multidrug Resistance to Cancer
1/04/14 → 31/08/15
Project: Research
Nerve Growth Factor Nanoparticles to Cross the Blood-Brain Barrier
NINDS: Neurological Disorders & Stroke
1/02/14 → 31/01/16
Project: Research
Research Output 2006 2018
22
Citations
(Scopus)
Current strategies for brain drug delivery
Dong, X., 1 Jan 2018, In : Theranostics. 8, 6, p. 1481-1493 13 p.Research output: Contribution to journal › Review article › Research › peer-review
Blood-Brain Barrier
Brain
Pharmaceutical Preparations
Nanoparticles
Multiple Sclerosis
Development and characterization of docetaxel-loaded nanoparticles for docetaxel-resistant castration-resistant prostate cancer
Tanaudommongkon, A., Tanaudommongkon, I., Prathipati, P., Nguyen, J. & Dong, X., 1 Jan 2017, In : Journal of Nanoscience and Nanotechnology. 17, 6, p. 3920-3926 7 p.Research output: Contribution to journal › Article › Research › peer-review
docetaxel
Castration
Nanoparticles
Prostatic Neoplasms
cancer
1
Citation
(Scopus)
Preparation and characterization of novel HDL-mimicking nanoparticles for nerve growth factor encapsulation
Zhu, J. & Dong, X., 22 May 2017, In : Journal of Visualized Experiments. 2017, 123, e55584.Research output: Contribution to journal › Article › Research › peer-review
Lipoproteins
Nerve Growth Factor
HDL Lipoproteins
Encapsulation
Nanoparticles
4
Citations
(Scopus)
Development and in vivo evaluation of child-friendly lopinavir/ritonavir pediatric granules utilizing novel in situ self-assembly nanoparticles
Pham, K., Li, D., Guo, S., Penzak, S. R. & Dong, X., 28 Mar 2016, In : Journal of Controlled Release. 226, p. 88-97 10 p.Research output: Contribution to journal › Article › Research › peer-review
Lopinavir
Ritonavir
Nanoparticles
Pediatrics
Nanotechnology
3
Citations
(Scopus)
Development of novel HDL-mimicking α-tocopherol-coated nanoparticles to encapsulate nerve growth factor and evaluation of biodistribution
Prathipati, P., Zhu, J. & Dong, X., 1 Nov 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 108, p. 126-135 10 p.Research output: Contribution to journal › Article › Research › peer-review
Tocopherols
Nerve Growth Factor
HDL Lipoproteins
Nanoparticles
Ions