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Xiaowei Dong, PhD

  • 835 Citations
  • 7 h-Index
20062020

Research output per year

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Personal profile

Area of Expertise

Dr. Dong’s research interests include pharmaceutical analysis/bioanalysis, drug formulation, and delivery. She develops novel formulation nanotechnologies to improve bioavailability of oral drugs and deliver macromolecules such as siRNAs and proteins. In addition to novel drug formulations, her lab evaluates these formulations for therapeutic efficacy (e.g. anticancer drugs), pharmacokinetics, and biodistribution. Thus, her lab has the capacity to perform bioassays for both small molecules and macromolecules. Additionally, she collaborates with the clinical pharmacy to test stability of compounding medications and Y-site compatibility.

Education/Academic qualification

BS in Industrial Analysis

MS in Applied Chemistry, East China University of Science and Technology

PhD in Pharmaceutical Sciences, University of Kentucky

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Projects

Nanoparticle Drug Delivery to Overcome Multidrug Resistance to Cancer

Dong, X.

Intramural Research(UNTHSC)

1/04/14 → 31/08/15

Project: Research

Nerve Growth Factor Nanoparticles to Cross the Blood-Brain Barrier

Dong, X.

NINDS: Neurological Disorders & Stroke

1/02/14 → 31/01/17

Project: Research

Nerve Growth Factor Nanoparticles to Cross the Blood-Brain Barrier

Dong, X.

1/02/14 → 31/01/15

Project: Research

Research Output

  • 835 Citations
  • 7 h-Index
  • 11 Article
  • 2 Review article

Curcumin nanoparticles and their cytotoxicity in docetaxel-resistant castration-resistant prostate cancer cells

Tanaudommongkon, I., Tanaudommongkon, A., Prathipati, P., Nguyen, J. T., Keller, E. T. & Dong, X., Aug 2020, In : Biomedicines. 8, 8, 253.

Research output: Contribution to journal › Article

Open Access
    • 1 Scopus citations

    Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

    Chaudhari, K., Wang, J., Xu, Y., Winters, A., Wang, L., Dong, X., Cheng, E. Y., Liu, R. & Yang, S. H., Jun 2020, In : PLoS ONE. 15, 6, e0234571.

    Research output: Contribution to journal › Article

    Open Access

    • Current strategies for brain drug delivery

    Dong, X., 2018, In : Theranostics. 8, 6, p. 1481-1493 13 p.

    Research output: Contribution to journal › Review article

    • 141 Scopus citations

    Development and characterization of docetaxel-loaded nanoparticles for docetaxel-resistant castration-resistant prostate cancer

    Tanaudommongkon, A., Tanaudommongkon, I., Prathipati, P., Nguyen, J. & Dong, X., 1 Jan 2017, In : Journal of Nanoscience and Nanotechnology. 17, 6, p. 3920-3926 7 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Preparation and characterization of novel HDL-mimicking nanoparticles for nerve growth factor encapsulation

    Zhu, J. & Dong, X., 22 May 2017, In : Journal of Visualized Experiments. 2017, 123, e55584.

    Research output: Contribution to journal › Article

    • 2 Scopus citations