Research output per year
Research output per year
- 50 - 65 out of 65 results
Search results
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Antibacterial activity of the novel semisynthetic lantibiotic NVB333 in vitro and in experimental infection models
Boakes, S., Weiss, W. J., Vinson, M., Wadman, S. & Dawson, M. J., 1 Dec 2016, In: Journal of Antibiotics. 69, 12, p. 850-857 8 p.Research output: Contribution to journal › Article › peer-review
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Mutacin 1140 lantibiotic variants are efficacious against Clostridium difficile infection
Kers, J. A., Sharp, R. E., Defusco, A. W., Park, J. H., Xu, J., Pulse, M. E., Weiss, W. J. & Handfield, M., 16 Mar 2018, In: Frontiers in Microbiology. 9, MAR, 415.Research output: Contribution to journal › Article › peer-review
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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes
Trout, R. E., Zulli, A., Mesaros, E., Jackson, R. W., Boyd, S., Liu, B., Hamrick, J., Daigle, D., Chatwin, C. L., John, K., McLaughlin, L., Cusick, S. M., Weiss, W. J., Pulse, M. E., Pevear, D. C., Moeck, G., Xerri, L. & Burns, C. J., 22 Jul 2021, In: Journal of Medicinal Chemistry. 64, 14, p. 10155-10166 12 p.Research output: Contribution to journal › Article › peer-review
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C1-CBP-vancomycin: Impact of a Vancomycin C-Terminus Trimethylammonium Cation on Pharmacological Properties and Insights into Its Newly Introduced Mechanism of Action
Wu, Z. C., Isley, N. A., Okano, A., Weiss, W. J. & Boger, D. L., 7 Feb 2020, In: Journal of Organic Chemistry. 85, 3, p. 1365-1375 11 p.Research output: Contribution to journal › Article › peer-review
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Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum β-lactamase inhibitors: Evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods
Venkatesan, A. M., Agarwal, A., Abe, T., Ushirogochi, H., Yamamura, I., Ado, M., Tsuyoshi, T., Dos Santos, O., Gu, Y., Sum, F. W., Li, Z., Francisco, G., Lin, Y. I., Petersen, P. J., Yang, Y., Kumagai, T., Weiss, W. J., Shlaes, D. M., Knox, J. R. & Mansour, T. S., 27 Jul 2006, In: Journal of Medicinal Chemistry. 49, 15, p. 4623-4637 15 p.Research output: Contribution to journal › Article › peer-review
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Protection of hamsters from mortality by reducing fecal moxifloxacin concentration with DAV131A in a model of moxifloxacin-induced Clostridium difficile colitis
Burdet, C., Sayah-Jeanne, S., Nguyen, T. T., Miossec, C., Saint-Lu, N., Pulse, M., Weiss, W., Andremont, A., Mentré, F. & De Gunzburg, J., 2017, In: Antimicrobial agents and chemotherapy. 61, 10Research output: Contribution to journal › Article › peer-review
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Simultaneous determination of rifampicin and levofloxacin concentrations in catheter segments from a mouse model of a device-related infection by liquid chromatography/electrospray ionization tandem mass spectrometry
Bao, D., Truong, T. T., Renick, P. J., Pulse, M. E. & Weiss, W. J., 13 Mar 2008, In: Journal of Pharmaceutical and Biomedical Analysis. 46, 4, p. 723-727 5 p.Research output: Contribution to journal › Article › peer-review
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Small molecule inhibitors of staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis
Olson, P. D., Kuechenmeister, L. J., Anderson, K. L., Daily, S., Beenken, K. E., Roux, C. M., Reniere, M. L., Lewis, T. L., Weiss, W. J., Pulse, M., Nguyen, P., Simecka, J. W., Morrison, J. M., Sayood, K., Asojo, O. A., Smeltzer, M. S., Skaar, E. P. & Dunman, P. M., Feb 2011, In: PLoS Pathogens. 7, 2, e1001287.Research output: Contribution to journal › Article › peer-review
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Treatment and prevention of recurrent Clostridium difficile infection with functionalized bovine antibody-enriched whey in a hamster primary infection model
Heidebrecht, H. J., Weiss, W. J., Pulse, M., Lange, A., Gisch, K., Kliem, H., Mann, S., Pfaffl, M. W., Kulozik, U. & von Eichel-Streiber, C., Feb 2019, In: Toxins. 11, 2, 98.Research output: Contribution to journal › Article › peer-review
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In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection
Weiss, W. J., Pulse, M. E., Nguyen, P. & Growcott, E. J., Apr 2019, In: Antimicrobial agents and chemotherapy. 63, 4, e02214-18.Research output: Contribution to journal › Article › peer-review
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Perturbation of Staphylococcus aureus gene expression by the enoyl-acyl carrier protein reductase inhibitor AFN-1252
Parsons, J. B., Kukula, M., Jackson, P., Pulse, M., Simecka, J. W., Valtierra, D., Weiss, W. J., Kaplan, N. & Rock, C. O., May 2013, In: Antimicrobial agents and chemotherapy. 57, 5, p. 2182-2190 9 p.Research output: Contribution to journal › Article › peer-review
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Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a staphylococcus aureus dermonecrosis model
Hilliard, J. J., Datta, V., Tkaczyk, C., Hamilton, M., Sadowska, A., Jones-Nelson, O., O'Day, T., Weiss, W. J., Szarka, S., Nguyen, V., Prokai, L., Suzich, J. A., Stover, C. K. & Sellmana, B. R., 1 Jan 2015, In: Antimicrobial agents and chemotherapy. 59, 1, p. 299-308 10 p.Research output: Contribution to journal › Article › peer-review
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Pharmacological, toxicological, and dose range assessment of OG716, a novel lantibiotic for the treatment of clostridium difficile-associated infection
Pulse, M. E., Weiss, W. J., Kers, J. A., DeFusco, A. W., Park, J. H. & Handfield, M., Apr 2019, In: Antimicrobial agents and chemotherapy. 63, 4, e01904-18.Research output: Contribution to journal › Article › peer-review
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In vivo assessment of smt 19969 in a hamster model of clostridium difficile infection
Weiss, W., Pulse, M. & Vickers, R., 1 Oct 2014, In: Antimicrobial agents and chemotherapy. 58, 10, p. 5714-5718 5 p.Research output: Contribution to journal › Article › peer-review
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Saccharomicins, novel heptadecaglycoside antibiotics produced by Saccharothrix espanaensis: Antibacterial and mechanistic activities
Singh, M. P., Petersen, P. J., Weiss, W. J., Kong, F. & Greenstein, M., 2000, In: Antimicrobial agents and chemotherapy. 44, 8, p. 2154-2159 6 p.Research output: Contribution to journal › Article › peer-review