Projects per year
Personal profile
Area of Expertise
Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.
Education/Academic qualification
MS in Biology, Fairleigh Dickinson University
BS in Microbiology, Rutgers University
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Collaborations and top research areas from the last five years
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PreClinical Models of Infectio
Weiss, W. (PI)
NIAID: Allergy and Infectious Diseases
15/07/24 → 14/07/31
Project: Research
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In vivo activities of peptidic prodrugs of novel aminomethyl tetrahydrofuranyl-1β-methylcarbapenems
Weiss, W. J., Mikels, S. M., Petersen, P. J., Jacobus, N. V., Bitha, P., Lin, Y. I. & Testa, R. T., Mar 1999, In: Antimicrobial agents and chemotherapy. 43, 3, p. 460-464 5 p.Research output: Contribution to journal › Article › peer-review
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Mutacin 1140 lantibiotic variants are efficacious against Clostridium difficile infection
Kers, J. A., Sharp, R. E., Defusco, A. W., Park, J. H., Xu, J., Pulse, M. E., Weiss, W. J. & Handfield, M., 16 Mar 2018, In: Frontiers in Microbiology. 9, MAR, 415.Research output: Contribution to journal › Article › peer-review
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OG716: Designing a fit-for-purpose lantibiotic for the treatment of Clostridium difficile infections
Kers, J. A., DeFusco, A. W., Park, J. H., Xu, J., Pulse, M. E., Weiss, W. J. & Handfield, M., Jun 2018, In: PLoS ONE. 13, 6, e0197467.Research output: Contribution to journal › Article › peer-review
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Activity of meropenem-vaborbactam against carbapenem- resistant enterobacteriaceae in a murine model of pyelonephritis
Weiss, W. J., Pulse, M. E., Nguyen, P., Peterson, K., Silva, J., Simecka, J. W., Valtierra, D., Sabet, M. & Griffith, D. C., Jan 2018, In: Antimicrobial agents and chemotherapy. 62, 1, e01439.Research output: Contribution to journal › Article › peer-review
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Pharmacological, toxicological, and dose range assessment of OG716, a novel lantibiotic for the treatment of clostridium difficile-associated infection
Pulse, M. E., Weiss, W. J., Kers, J. A., DeFusco, A. W., Park, J. H. & Handfield, M., Apr 2019, In: Antimicrobial agents and chemotherapy. 63, 4, e01904-18.Research output: Contribution to journal › Article › peer-review