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William Weiss, MS

  • 2146 Citations
  • 25 h-Index
1985 …2020

Research output per year

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Personal profile

Area of Expertise

Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.

Education/Academic qualification

MS in Biology, Fairleigh Dickinson University

BS in Microbiology, Rutgers University

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Projects

FCCDC 2019-02: Model Development and Test Article Efficacy in a Disseminated Aspergillus and Cutaneous Fungal Infection (Aspergillus & Fusarium) Models

Simecka, J. & Weiss, W.

Fox Chase Chemical Diversity Center, Inc

22/10/19 → 21/10/20

Project: Research

Development and Validation of a Chronic Murine Lung Infection Model with S. Aureus

Simecka, J. & Weiss, W.

Janssen Pharmaceuticals

17/10/19 → 16/10/20

Project: Research

Pre-Clinical Services Agreements

Simecka, J. & Weiss, W.

Pre-Clinical Services Funding Pool

1/09/19 → 31/08/20

Project: Research

Therapeutics Testing In Murine Models of Bacterial Thigh & Lung Infections

Weiss, W.

Project: Research

TASK X1: THERAPEUTICS TESTING IN MURINE MODELS OF BACTERIAL THIGH AND LUNG INFECTIONS

Weiss, W.

Project: Research

Research Output

  • 2146 Citations
  • 25 h-Index
  • 57 Article

C1-CBP-vancomycin: Impact of a Vancomycin C-Terminus Trimethylammonium Cation on Pharmacological Properties and Insights into Its Newly Introduced Mechanism of Action

Wu, Z. C., Isley, N. A., Okano, A., Weiss, W. J. & Boger, D. L., 7 Feb 2020, In : Journal of Organic Chemistry. 85, 3, p. 1365-1375 11 p.

Research output: Contribution to journal › Article

    • DAV131A Protects Hamsters from Lethal Clostridioides difficile Infection Induced by Fluoroquinolones

    Saint-Lu, N., Burdet, C., Sablier-Gallis, F., Corbel, T., Nevière, A., Sayah-Jeanne, S., Pulse, M., Weiss, W., Ferreira, S., Andremont, A., Mentré, F. & de Gunzburg, J., 1 Jan 2020, In : Antimicrobial agents and chemotherapy. 64, 1, e01196-19.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

    Liu, B., Trout, R. E. L., Chu, G. H., Mcgarry, D., Jackson, R. W., Hamrick, J. C., Daigle, D. M., Cusick, S. M., Pozzi, C., De Luca, F., Benvenuti, M., Mangani, S., Docquier, J. D., Weiss, W. J., Pevear, D. C., Xerri, L. & Burns, C. J., 26 Mar 2020, In : Journal of Medicinal Chemistry. 63, 6, p. 2789-2801 13 p.

    Research output: Contribution to journal › Article

    Open Access
    • 13 Scopus citations

    In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection

    Weiss, W. J., Pulse, M. E., Nguyen, P. & Growcott, E. J., Apr 2019, In : Antimicrobial agents and chemotherapy. 63, 4, e02214-18.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Liposomal mupirocin holds promise for systemic treatment of invasive Staphylococcus aureus infections

    Goldmann, O., Cern, A., Muesken, M., Rohde, M., Weiss, W., Barenholz, Y. & Medina, E., 28 Dec 2019, In : Journal of Controlled Release. 316, p. 292-301 10 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations