Projects per year
Personal profile
Area of Expertise
Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.
Education/Academic qualification
MS in Biology, Fairleigh Dickinson University
BS in Microbiology, Rutgers University
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Dive into the research topics where William Weiss is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Development and Validation of a Chronic Murine Lung Infection Model with S. Aureus
17/10/19 → 16/10/20
Project: Research
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Pre-Clinical Services Agreements
Pre-Clinical Services Funding Pool
1/09/19 → 31/08/20
Project: Research
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Development and Validation of a Chronic Murine Lung Infection Model with P. aeruginosa
18/04/19 → 17/04/20
Project: Research
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Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens
Ma, Z., He, S., Yuan, Y., Zhuang, Z., Liu, Y., Wang, H., Chen, J., Xu, X., Ding, C., Molodtsov, V., Lin, W., Robertson, G. T., Weiss, W. J., Pulse, M., Nguyen, P., Duncan, L., Doyle, T., Ebright, R. H. & Lynch, A. S., 24 Mar 2022, In: Journal of Medicinal Chemistry. 65, 6, p. 4481-4495 15 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes
Trout, R. E., Zulli, A., Mesaros, E., Jackson, R. W., Boyd, S., Liu, B., Hamrick, J., Daigle, D., Chatwin, C. L., John, K., McLaughlin, L., Cusick, S. M., Weiss, W. J., Pulse, M. E., Pevear, D. C., Moeck, G., Xerri, L. & Burns, C. J., 22 Jul 2021, In: Journal of Medicinal Chemistry. 64, 14, p. 10155-10166 12 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
FDA public workshop summary: Advancing animal models for antibacterial drug development
Byrne, J. M., Waack, U., Weinstein, E. A., Joshi, A., Shurland, S. M., Iarikov, D., Bulitta, J. B., Diep, B. A., Guina, T., Hope, W. W., Lawrenz, M. B., Lepak, A. J., Luna, B. M., Miesel, L., Phipps, A. J., Walsh, T. J., Weiss, W., Amini, T. & Farley, J. J., Jan 2021, In: Antimicrobial agents and chemotherapy. 65, 1, e01983-20.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations -
Immunopotentiation by Lymph-Node Targeting of a Malaria Transmission-Blocking Nanovaccine
Howard, G. P., Bender, N. G., Khare, P., López-Gutiérrez, B., Nyasembe, V., Weiss, W. J., Simecka, J. W., Hamerly, T., Mao, H. Q. & Dinglasan, R. R., 27 Aug 2021, In: Frontiers in Immunology. 12, 729086.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Microbiological characterization of VNRX-5236, a broad-spectrum b-lactamase inhibitor for rescue of the orally bioavailable cephalosporin ceftibuten as a carbapenem-sparing agent against strains of enterobacterales expressing extended-spectrum b-lactamases and serine carbapenemases
Chatwin, C. L., Hamrick, J. C., Trout, R. E. L., Myers, C. L., Cusick, S. M., Weiss, W. J., Pulse, M. E., Xerri, L., Burns, C. J., Moeck, G., Daigle, D. M., John, K., Uehara, T. & Pevear, D. C., Aug 2021, In: Antimicrobial agents and chemotherapy. 65, 8, e00552.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations