Projects per year
Personal profile
Area of Expertise
Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.
Education/Academic qualification
MS in Biology, Fairleigh Dickinson University
BS in Microbiology, Rutgers University
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Collaborations and top research areas from the last five years
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PreClinical Models of Infectio
Weiss, W. (PI)
NIAID: Allergy and Infectious Diseases
15/07/24 → 14/07/31
Project: Research
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In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection
Weiss, W. J., Pulse, M. E., Nguyen, P. & Growcott, E. J., Apr 2019, In: Antimicrobial agents and chemotherapy. 63, 4, e02214-18.Research output: Contribution to journal › Article › peer-review
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DAV131A Protects Hamsters from Lethal Clostridioides difficile Infection Induced by Fluoroquinolones
Saint-Lu, N., Burdet, C., Sablier-Gallis, F., Corbel, T., Nevière, A., Sayah-Jeanne, S., Pulse, M., Weiss, W., Ferreira, S., Andremont, A., Mentré, F. & de Gunzburg, J., 2020, In: Antimicrobial agents and chemotherapy. 64, 1, e01196-19.Research output: Contribution to journal › Article › peer-review
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FDA public workshop summary: Advancing animal models for antibacterial drug development
Byrne, J. M., Waack, U., Weinstein, E. A., Joshi, A., Shurland, S. M., Iarikov, D., Bulitta, J. B., Diep, B. A., Guina, T., Hope, W. W., Lawrenz, M. B., Lepak, A. J., Luna, B. M., Miesel, L., Phipps, A. J., Walsh, T. J., Weiss, W., Amini, T. & Farley, J. J., Jan 2021, In: Antimicrobial agents and chemotherapy. 65, 1, e01983-20.Research output: Contribution to journal › Review article › peer-review
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Design, Synthesis, and Characterization of TNP-2198, a Dual-Targeted Rifamycin-Nitroimidazole Conjugate with Potent Activity against Microaerophilic and Anaerobic Bacterial Pathogens
Ma, Z., He, S., Yuan, Y., Zhuang, Z., Liu, Y., Wang, H., Chen, J., Xu, X., Ding, C., Molodtsov, V., Lin, W., Robertson, G. T., Weiss, W. J., Pulse, M., Nguyen, P., Duncan, L., Doyle, T., Ebright, R. H. & Lynch, A. S., 24 Mar 2022, In: Journal of Medicinal Chemistry. 65, 6, p. 4481-4495 15 p.Research output: Contribution to journal › Article › peer-review
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Oral Immunotherapy with Human Secretory Immunoglobulin A Improves Survival in the Hamster Model of Clostridioides difficile Infection
Chiari, E. F., Weiss, W., Simon, M. R., Kiessig, S. T., Pulse, M., Brown, S. C., Gerding, H. R., Mandago, M., Gisch, K. & Von Eichel-Streiber, C., 15 Oct 2021, In: Journal of Infectious Diseases. 224, 8, p. 1394-1397 4 p.Research output: Contribution to journal › Article › peer-review