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Personal profile

Area of Expertise

Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.

Education/Academic qualification

MS in Biology, Fairleigh Dickinson University

BS in Microbiology, Rutgers University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2011 2019

Research Output 1985 2019

  • 1979 Citations
  • 24 h-Index
  • 52 Article

Pharmacological, toxicological, and dose range assessment of OG716, a novel lantibiotic for the treatment of clostridium difficile-associated infection

Pulse, M. E., Weiss, W., Kers, J. A., DeFusco, A. W., Park, J. H. & Handfield, M., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. e01904-18.

Research output: Contribution to journalArticleResearchpeer-review

Clostridium difficile

Treatment and prevention of recurrent Clostridium difficile infection with functionalized bovine antibody-enriched whey in a hamster primary infection model

Heidebrecht, H. J., Weiss, W., Pulse, M., Lange, A., Gisch, K., Kliem, H., Mann, S., Pfaffl, M. W., Kulozik, U. & von Eichel-Streiber, C., 1 Feb 2019, In : Toxins. 11, 2, 98.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Clostridium Infections
Clostridium difficile
6 Citations (Scopus)

Activity of meropenem-vaborbactam against carbapenem- resistant enterobacteriaceae in a murine model of pyelonephritis

Weiss, W., Pulse, M. E., Nguyen, P., Peterson, K., Silva, J., Simecka, J., Valtierra, D., Sabet, M. & Griffith, D. C., 1 Jan 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, e01439.

Research output: Contribution to journalArticleResearchpeer-review

Klebsiella pneumoniae
1 Citation (Scopus)

Antibiotic-induced dysbiosis predicts mortality in an animal model of clostridium difficile infection

Burdet, C., Sayah-Jeanne, S., Nguyen, T. T., Hugon, P., Sablier-Gallis, F., Saint-Lu, N., Corbel, T., Ferreira, S., Pulse, M., Weiss, W., Andremont, A., Mentré, F. & De Gunzburg, J., 1 Oct 2018, In : Antimicrobial Agents and Chemotherapy. 62, 10, e00925.

Research output: Contribution to journalArticleResearchpeer-review

Clostridium Infections
Clostridium difficile
Animal Models
Anti-Bacterial Agents
7 Citations (Scopus)

Mutacin 1140 lantibiotic variants are efficacious against Clostridium difficile infection

Kers, J. A., Sharp, R. E., Defusco, A. W., Park, J. H., Xu, J., Pulse, M. E., Weiss, W. & Handfield, M., 16 Mar 2018, In : Frontiers in Microbiology. 9, MAR, 415.

Research output: Contribution to journalArticleResearchpeer-review

Clostridium Infections
Clostridium difficile