Projects per year
Personal profile
Area of Expertise
Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.
Education/Academic qualification
MS in Biology, Fairleigh Dickinson University
BS in Microbiology, Rutgers University
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Task C08:Vaccine Testing in Aerosol Challenge Monkeypox NHP Model
Weiss, W., SAIA, T., VANCOTT, T., MIRSALIS, J., BRUCE, M., MEISTER, G., MENNE, S., BARRETT, A., BARRETT, A., BARRETT, A., PALESE, P., BULLER, M., LEWIS, M., KORBA, B., KORBA, B., PARISH, T., PARISH, T., RAYNER, J., RICHTER, S., Minyard, M. B., NOAH, J., NOAH, J., Ananthan, S., PRICHARD, M., PRICHARD, M., PRICHARD, M., PATTERSON, T., PATTERSON, T., PATTERSON, T., SHAW, E., SHAW, E., GRIFFISS, M., GRIFFISS, M. & HOOK III, E.
National Institute of Allergy and Infectious Diseases
Project: Research
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Discovery of VNRX-7145 (VNRX-5236 Etzadroxil): An Orally Bioavailable β-Lactamase Inhibitor for Enterobacterales Expressing Ambler Class A, C, and D Enzymes
Trout, R. E., Zulli, A., Mesaros, E., Jackson, R. W., Boyd, S., Liu, B., Hamrick, J., Daigle, D., Chatwin, C. L., John, K., McLaughlin, L., Cusick, S. M., Weiss, W. J., Pulse, M. E., Pevear, D. C., Moeck, G., Xerri, L. & Burns, C. J., 22 Jul 2021, In: Journal of Medicinal Chemistry. 64, 14, p. 10155-10166 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
FDA public workshop summary: Advancing animal models for antibacterial drug development
Byrne, J. M., Waack, U., Weinstein, E. A., Joshi, A., Shurland, S. M., Iarikov, D., Bulitta, J. B., Diep, B. A., Guina, T., Hope, W. W., Lawrenz, M. B., Lepak, A. J., Luna, B. M., Miesel, L., Phipps, A. J., Walsh, T. J., Weiss, W., Amini, T. & Farley, J. J., Jan 2021, In: Antimicrobial agents and chemotherapy. 65, 1, e01983-20.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations -
Immunopotentiation by Lymph-Node Targeting of a Malaria Transmission-Blocking Nanovaccine
Howard, G. P., Bender, N. G., Khare, P., López-Gutiérrez, B., Nyasembe, V., Weiss, W. J., Simecka, J. W., Hamerly, T., Mao, H. Q. & Dinglasan, R. R., 27 Aug 2021, In: Frontiers in Immunology. 12, 729086.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Microbiological characterization of VNRX-5236, a broad-spectrum b-lactamase inhibitor for rescue of the orally bioavailable cephalosporin ceftibuten as a carbapenem-sparing agent against strains of enterobacterales expressing extended-spectrum b-lactamases and serine carbapenemases
Chatwin, C. L., Hamrick, J. C., Trout, R. E. L., Myers, C. L., Cusick, S. M., Weiss, W. J., Pulse, M. E., Xerri, L., Burns, C. J., Moeck, G., Daigle, D. M., John, K., Uehara, T. & Pevear, D. C., Aug 2021, In: Antimicrobial agents and chemotherapy. 65, 8, e00552.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Oral Immunotherapy with Human Secretory Immunoglobulin A Improves Survival in the Hamster Model of Clostridioides difficile Infection
Chiari, E. F., Weiss, W., Simon, M. R., Kiessig, S. T., Pulse, M., Brown, S. C., Gerding, H. R., Mandago, M., Gisch, K. & Von Eichel-Streiber, C., 15 Oct 2021, In: Journal of Infectious Diseases. 224, 8, p. 1394-1397 4 p.Research output: Contribution to journal › Article › peer-review