Projects per year
Personal profile
Area of Expertise
Pre-Clinical Services evaluate new therapies against infections using animal models. These studies are done in collaboration with pharmaceutical and academic researchers, and several of these therapies are now being used clinically to treat patients.
Education/Academic qualification
MS in Biology, Fairleigh Dickinson University
BS in Microbiology, Rutgers University
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Collaborations and top research areas from the last five years
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PreClinical Models of Infectio
Weiss, W. (PI)
NIAID: Allergy and Infectious Diseases
15/07/24 → 14/07/31
Project: Research
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In vitro and in vivo activities of LJC10,627, a new carbapenem with stability to dehydropeptidase I
Petersen, P. J., Jacobus, N. V., Weiss, W. J. & Testa, R. T., 1991, In: Antimicrobial agents and chemotherapy. 35, 1, p. 203-207 5 p.Research output: Contribution to journal › Article › peer-review
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Small molecule inhibitors of staphylococcus aureus RnpA alter cellular mRNA turnover, exhibit antimicrobial activity, and attenuate pathogenesis
Olson, P. D., Kuechenmeister, L. J., Anderson, K. L., Daily, S., Beenken, K. E., Roux, C. M., Reniere, M. L., Lewis, T. L., Weiss, W. J., Pulse, M., Nguyen, P., Simecka, J. W., Morrison, J. M., Sayood, K., Asojo, O. A., Smeltzer, M. S., Skaar, E. P. & Dunman, P. M., Feb 2011, In: PLoS Pathogens. 7, 2, e1001287.Research output: Contribution to journal › Article › peer-review
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FDA public workshop summary: Advancing animal models for antibacterial drug development
Byrne, J. M., Waack, U., Weinstein, E. A., Joshi, A., Shurland, S. M., Iarikov, D., Bulitta, J. B., Diep, B. A., Guina, T., Hope, W. W., Lawrenz, M. B., Lepak, A. J., Luna, B. M., Miesel, L., Phipps, A. J., Walsh, T. J., Weiss, W., Amini, T. & Farley, J. J., Jan 2021, In: Antimicrobial agents and chemotherapy. 65, 1, e01983-20.Research output: Contribution to journal › Review article › peer-review
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In Vivo Efficacy of Novel Monobactam LYS228 in Murine Models of Carbapenemase-Producing Klebsiella pneumoniae Infection
Weiss, W. J., Pulse, M. E., Nguyen, P. & Growcott, E. J., Apr 2019, In: Antimicrobial agents and chemotherapy. 63, 4, e02214-18.Research output: Contribution to journal › Article › peer-review
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Pharmacological, toxicological, and dose range assessment of OG716, a novel lantibiotic for the treatment of clostridium difficile-associated infection
Pulse, M. E., Weiss, W. J., Kers, J. A., DeFusco, A. W., Park, J. H. & Handfield, M., Apr 2019, In: Antimicrobial agents and chemotherapy. 63, 4, e01904-18.Research output: Contribution to journal › Article › peer-review