• 1148 Citations
  • 17 h-Index
20022019

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 1148 Citations
  • 17 h-Index
  • 31 Article
  • 5 Review article
  • 1 Comment/debate
Filter
Article
2002

Mutational analysis of conserved residues in Hhal DNA methyltransferase

Sankpal, U. T. & Rao, D. N., 15 Jun 2002, In : Nucleic Acids Research. 30, 12, p. 2628-2638 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Water-assisted dual mode cofactor recognition by HhaI DNA methyltransferase

Swaminathan, C. P., Sankpal, U. T., Rao, D. N. & Surolia, A., 8 Feb 2002, In : Journal of Biological Chemistry. 277, 6, p. 4042-4049 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
2004

DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system

Geiman, T. M., Sankpal, U. T., Robertson, A. K., Zhao, Y., Zhao, Y. & Robertson, K. D., 28 May 2004, In : Biochemical and Biophysical Research Communications. 318, 2, p. 544-555 12 p.

Research output: Contribution to journalArticle

80 Scopus citations

Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro

Robertson, A. K., Geiman, T. M., Sankpal, U. T., Hager, G. L. & Robertson, K. D., 10 Sep 2004, In : Biochemical and Biophysical Research Communications. 322, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

57 Scopus citations

Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery

Geiman, T. M., Sankpal, U. T., Robertson, A. K., Chen, Y., Mazumdar, M., Heale, J. T., Schmiesing, J. A., Kim, W., Yokomori, K., Zhao, Y. & Robertson, K. D., 20 Jul 2004, In : Nucleic Acids Research. 32, 9, p. 2716-2729 14 p.

Research output: Contribution to journalArticle

92 Scopus citations

Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription

Ling, Y., Sankpal, U. T., Robertson, A. K., McNally, J. G., Karpova, T. & Robertson, K. D., 10 Mar 2004, In : Nucleic Acids Research. 32, 2, p. 598-610 13 p.

Research output: Contribution to journalArticle

99 Scopus citations
2008

DNA methylation inhibitor 5-aza-2′-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B

Palii, S. S., Van Emburgh, B. O., Sankpal, U. T., Brown, K. D. & Robertson, K. D., 1 Jan 2008, In : Molecular and Cellular Biology. 28, 2, p. 752-771 20 p.

Research output: Contribution to journalArticle

227 Scopus citations
2009

Activation of KATP channels increases anticancer drug delivery to brain tumors and survival

Ningaraj, N. S., Sankpal, U. T., Khaitan, D., Meister, E. A. & Vats, T., 14 Jan 2009, In : European Journal of Pharmacology. 602, 2-3, p. 188-193 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model

Ningaraj, N. S., Sankpal, U. T., Khaitan, D., Meister, E. A. & Vats, T. S., 15 Oct 2009, In : Cancer Biology and Therapy. 8, 20, p. 1924-1933 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

Khaitan, D., Sankpal, U. T., Weksler, B., Meister, E. A., Romero, I. A., Couraud, P. O. & Ningaraj, N. S., 29 Jul 2009, In : BMC Cancer. 9, 258.

Research output: Contribution to journalArticle

74 Scopus citations
2011

Nexus between hepatic enzyme modulation and cancer

Maliakal, C., Pius, H., Lee, C. M. & Sankpal, U. T., 1 Oct 2011, In : Current Trends in Biotechnology and Pharmacy. 5, 4, p. 1372-1382 11 p.

Research output: Contribution to journalArticle

Relevance of drug metabolizing enzyme activity modulation by tea polyphenols in the inhibition of esophageal tumorigenesis

Maliakal, P., Sankpal, U. T., Basha, R. M., Maliakal, C., Ledford, A. & Wanwimolruk, S., 1 Sep 2011, In : Medicinal chemistry. 7, 5, p. 480-487 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Therapeutic applications of NSAIDS in cancer: Special emphasis on tolfenamic acid

Basha, R. M., Baker, C. T., Sankpal, U. T., Ahmad, S., Safe, S., Abbruzzese, J. L. & Abdelrahim, M., 1 Jan 2011, In : Frontiers in Bioscience - Scholar. 3 S, 2, p. 797-805 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Tolfenamic acid inhibits ovarian cancer cell growth and decreases the expression of c-Met and survivin through suppressing specificity protein transcription factors

Basha, R. M., Ingersoll, S. B., Sankpal, U. T., Ahmad, S., Baker, C. H., Edwards, J. R., Holloway, R. W., Kaja, S. & Abdelrahim, M., 1 Jul 2011, In : Gynecologic Oncology. 122, 1, p. 163-170 8 p.

Research output: Contribution to journalArticle

41 Scopus citations
2012

Chemopreventive effects of tolfenamic acid against esophageal tumorigenesis in rats

Maliakal, P., Abdelrahim, M., Sankpal, U. T., Maliakal, C., Baker, C. H., Safe, S., Herrera, L. J., Abudayyeh, A., Kaja, S. & Basha, R., 1 Jun 2012, In : Investigational New Drugs. 30, 3, p. 853-861 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Small molecule tolfenamic acid inhibits PC-3 cell proliferation and invasion in vitro, and tumor growth in orthotopic mouse model for prostate cancer

Sankpal, U. T., Abdelrahim, M., Connelly, S. F., Lee, C. M., Madero-Visbal, R., Colon, J., Smith, J., Safe, S., Maliakal, P. & Basha, R. M., 1 Nov 2012, In : Prostate. 72, 15, p. 1648-1658 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver

Siddiqi, S. A., Shukoor, M. I., Tiwari, S., Sankpal, U. T., Maliakal, P., Connelly, S. F., Siddiqi, S. & Basha, R., Sep 2012, In : Integrative Biology (United Kingdom). 4, 9, p. 1122-1129 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2013

Anticancer activity of tolfenamic acid in medulloblastoma: A preclinical study

Eslin, D., Lee, C., Sankpal, U. T., Maliakal, P., Sutphin, R. M., Abraham, L. & Basha, R. M., 20 May 2013, In : Tumor Biology. 34, 5, p. 2781-2789 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Cellular and organismal toxicity of the anti-cancer small molecule, tolfenamic acid: A pre-clinical evaluation

Sankpal, U. T., Lee, C. M., Connelly, S. F., Kayaleh, O., Eslin, D., Sutphin, R., Goodison, S., Adwan, L., Zawia, N. H., Lichtenberger, L. M. & Basha, R., 1 Jan 2013, In : Cellular Physiology and Biochemistry. 32, 3, p. 675-686 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Tolfenamic acid inhibits neuroblastoma cell proliferation and induces apoptosis: A novel therapeutic agent for neuroblastoma

Eslin, D., Sankpal, U. T., Lee, C., Sutphin, R. M., Maliakal, P., Currier, E., Sholler, G., Khan, M. & Basha, R. M., 1 May 2013, In : Molecular Carcinogenesis. 52, 5, p. 377-386 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Anti-leukemic response of a NSAID, tolfenamic acid

Sutphin, R. M., Connelly, S. F., Lee, C. M., Sankpal, U. T., Eslin, D., Khan, M., Pius, H. & Basha, R., Jun 2014, In : Targeted Oncology. 9, 2, p. 135-144 10 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

Combination of 13 cis-retinoic acid and tolfenamic acid induces apoptosis and effectively inhibits high-risk neuroblastoma cell proliferation

Shelake, S., Eslin, D., Sutphin, R. M., Sankpal, U. T., Wadwani, A., Kenyon, L. E., Tabor-Simecka, L., Bowman, W. P., Vishwanatha, J. K. & Basha, R., 1 Nov 2015, In : International Journal of Developmental Neuroscience. 46, p. 92-99 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Association of Sp1 and survivin in epithelial ovarian cancer: Sp1 inhibitor and cisplatin, a novel combination for inhibiting epithelial ovarian cancer cell proliferation

Sankpal, U. T., Ingersoll, S. B., Ahmad, S., Holloway, R. W., Bhat, V. B., Simecka, J. W., Daniel, L., Kariali, E., Vishwanatha, J. K. & Basha, R., 1 Oct 2016, In : Tumor Biology. 37, 10, p. 14259-14269 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Combination of Tolfenamic acid and curcumin induces colon cancer cell growth inhibition through modulating specific transcription factors and reactive oxygen species

Sankpal, U. T., Nagaraju, G. P., Gottipolu, S. R., Hurtado, M., Jordan, C. G., Simecka, J. W., Shoji, M., El-Rayes, B. & Basha, R., 1 Jan 2016, In : Oncotarget. 7, 3, p. 3186-3200 15 p.

Research output: Contribution to journalArticle

32 Scopus citations
17 Scopus citations
2017

Targeting specificity protein 1 transcription factor and survivin using tolfenamic acid for inhibiting Ewing sarcoma cell growth

Shelake, S., Sankpal, U. T., Paul Bowman, W., Wise, M., Ray, A. & Basha, R., 1 Apr 2017, In : Investigational New Drugs. 35, 2, p. 158-165 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Tolfenamic acid-induced alterations in genes and pathways in pancreatic cancer cells

Sankpal, U. T., Goodison, S., Jones-Pauley, M., Hurtado, M., Zhang, F. & Basha, R., 1 Jan 2017, In : Oncotarget. 8, 9, p. 14593-14603 11 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Novel survivin inhibitor for suppressing pancreatic cancer cells growth via downregulating Sp1 and Sp3 transcription factors

Hurtado, M., Sankpal, U. T., Kaba, A., Mahammad, S., Chhabra, J., Brown, D. T., Gurung, R. K., Holder, A. A., Vishwanatha, J. K. & Basha, R., 1 Dec 2018, In : Cellular Physiology and Biochemistry. 51, 4, p. 1894-1907 14 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

Clotam enhances anti-proliferative effect of vincristine in Ewing sarcoma cells

Shelake, S., Sankpal, U. T., Eslin, D., Bowman, W. P., Simecka, J. W., Raut, S., Ray, A. & Basha, R., 15 Feb 2019, In : Apoptosis. 24, 1-2, p. 21-32 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combination of clotam and vincristine enhances anti-proliferative effect in medulloblastoma cells

Patil, S., Sankpal, U. T., Hurtado, M., Bowman, W. P., Murray, J., Borgmann, K., Ghorpade, A., Sutphin, R., Eslin, D. & Basha, R., 15 Jul 2019, In : Gene. 705, p. 67-76 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Copper-tolfenamic acid: evaluation of stability and anti-cancer activity

Hurtado, M., Sankpal, U. T., Chhabra, J., Brown, D. T., Maram, R., Patel, R., Gurung, R. K., Simecka, J., Holder, A. A. & Basha, R., 15 Feb 2019, In : Investigational New Drugs. 37, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

2 Scopus citations