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Research Output 1973 2019

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7 Citations (Scopus)

Ocular hypotensive effects of lofexidine, an alpha2‐adrenoreceptor agonist

Elko, E. E., Tran, T., Lal, H. & Yorio, T., 1 Jan 1988, In : Drug Development Research. 14, 2, p. 169-175 7 p.

Research output: Contribution to journalArticle

Intraocular Pressure
Clonidine
Rabbits
Topical Administration
lofexidine
21 Citations (Scopus)

Ocular Hypotensive Effects of Medetomidine and Its Analogs

Jin, Y., Wilson, S., Elko, E. E. & Yorio, T., 1 Jan 1991, In : Journal of Ocular Pharmacology. 7, 4, p. 285-296 12 p.

Research output: Contribution to journalArticle

Medetomidine
Adenylyl Cyclases
Rabbits
Cats
Imidazolines
5 Citations (Scopus)

Ocular α2-Receptor Subclasses and Antiglaucoma Efficacy

Jin, Y., Gooding, J. R. & Yorio, T., 1 Jan 1994, In : Journal of Ocular Pharmacology. 10, 1, p. 359-369 11 p.

Research output: Contribution to journalArticle

Adenylyl Cyclases
Guanylyl Imidodiphosphate
Guanosine Triphosphate
Imidazolines
Ciliary Body
10 Citations (Scopus)

Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells

He, S., Dibas, A., Yorio, T. & Prasanna, G., 1 Mar 2007, In : Experimental Biology and Medicine. 232, 3, p. 370-384 15 p.

Research output: Contribution to journalArticle

Astrocytoma
Endothelin-1
Phosphorylation
Cell proliferation
Mitogen-Activated Protein Kinases
25 Citations (Scopus)
Ocular Hypertension
Glaucoma
Dexamethasone
Glucocorticoids
Perfusion
22 Citations (Scopus)

Permeability of the rabbit colon in vitro

Yorio, T. & Bentley, P. J., 1 Jan 1977, In : American Journal of Physiology. 232, 1

Research output: Contribution to journalArticle

Amiloride
Amphotericin B
Permeability
Colon
Rabbits
2 Citations (Scopus)

Phenylarsine oxide inhibits phosphate uptake in human ciliary non- pigmented epithelial cells

Dibas, A., Prasanna, G. & Yorio, T., 1 Jan 1999, In : Journal of Ocular Pharmacology and Therapeutics. 15, 3, p. 241-250 10 p.

Research output: Contribution to journalArticle

Epithelial Cells
Phosphates
Sulfhydryl Reagents
Adenosine Triphosphate
Sodium

Phorbol myristic acetate (PMA) induced protein kinase C translocation in LLC-PK1 PIG kidney cells

Dibas, A. & Yorio, T., 1 Dec 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

protein kinase C
kidney cells
Protein Kinase C
Acetates
acetates
66 Citations (Scopus)

Phospholipase A and the mechanism of action of aldosterone

Yorio, T. & Bentley, P. J., 1 Dec 1978, In : Nature. 271, 5640, p. 79-81 3 p.

Research output: Contribution to journalArticle

Phospholipases A
Aldosterone
Urinary Bladder
Epithelial Cells
Quinacrine
3 Citations (Scopus)

Phospholipase C-induced "Na-channels" in the crystalline lens

Yorio, T. & Bentley, P. J., 1 Jan 1978, In : Experimental eye research. 26, 2, p. 165-176 12 p.

Research output: Contribution to journalArticle

Crystalline Lens
Type C Phospholipases
Lenses
Enzymes
Choline

Phospholipase secretion by amphibian epithelia

Yorio, T. & Bentley, P. J., 1 Jan 1977, In : Federation Proceedings. 36, 3

Research output: Contribution to journalArticle

Phospholipases
Amphibians
Epithelium
5 Citations (Scopus)

Phospholipid Changes during Adaptation to Acidosis in Urinary Bladder of Bufo marinus

Frazier, L. W. & Yorio, T., 1 Jan 1989, In : Proceedings of the Society for Experimental Biology and Medicine. 190, 4, p. 339-343 5 p.

Research output: Contribution to journalArticle

Bufo marinus
Acidosis
Phospholipids
Urinary Bladder
Anura
15 Citations (Scopus)

Phospholipids and Electrolyte Transport

Yorio, T. & Frazier, L. W., 1 Jan 1990, In : Proceedings of the Society for Experimental Biology and Medicine. 195, 3, p. 293-303 11 p.

Research output: Contribution to journalArticle

Second Messenger Systems
Electrolytes
Phospholipids
Ion Channels
Ions
4 Citations (Scopus)

Prostaglandin F(2α) inhibits acidification in H+-secreting epithelia

Page, R. D. & Yorio, T., 1 Jan 1990, In : Journal of Pharmacology and Experimental Therapeutics. 252, 3, p. 929-933 5 p.

Research output: Contribution to journalArticle

Prostaglandins F
Epithelium
Rana pipiens
Acidosis
Skin
8 Citations (Scopus)

Prostaglandin regulation of H+ secretion in amphibian epithelia

Yorio, T., Page, R. D. & Frazier, L. W., 1 Jan 1991, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 260, 5 29-5

Research output: Contribution to journalArticle

Prostaglandins H
Amphibians
Anura
Epithelium
Protons
16 Citations (Scopus)

Prostaglandins as Mediators of Acidification in the Urinary Bladder of Bufo marinus

Frazier, L. W. & Yorio, T., 1 Jan 1990, In : Proceedings of the Society for Experimental Biology and Medicine. 194, 1, p. 10-15 6 p.

Research output: Contribution to journalArticle

Bufo marinus
Acidification
Acidosis
Prostaglandins E
Anura
7 Citations (Scopus)

Protein kinase c activity and its relationship to myo-inositol uptake during hyperglycemic conditions in cultured bovine Lens epithelial cells

Cammarata, P. R., Fan, W., Jin, Y. & Yorio, T., 1 Jan 1993, In : Current Eye Research. 12, 5, p. 403-412 10 p.

Research output: Contribution to journalArticle

Inositol
Protein Kinases
Protein Kinase C
Lenses
Epithelial Cells
5 Citations (Scopus)

Protein Profiling of human nonpigmented ciliary epithelium cell secretome: The differentiation factors characterization for retinal ganglion cell line

Chung, T. W., Yang, M. H., Krishnamoorthy, R., Jong, S. B., Chu, P. Y., Yang, Y. H., Chen, W. C., Chen, S. C. J., Dibas, A., Yorio, T. & Tyan, Y. C., 12 Oct 2011, In : Journal of Biomedicine and Biotechnology. 2011, 901329.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Epithelium
Cell Line
Epithelial Cells
Proteins
36 Citations (Scopus)

Regulation of endothelin-1 in human non-pigmented ciliary epithelial cells by tumor necrosis factor-α

Prasanna, G., Dibas, A., Tao, W., White, K. & Yorio, T., 1 Jan 1998, In : Experimental Eye Research. 66, 1, p. 9-18 10 p.

Research output: Contribution to journalArticle

Endothelin-1
Tumor Necrosis Factor-alpha
Epithelial Cells
Aqueous Humor
Cytokines
53 Citations (Scopus)
Trabecular Meshwork
Glucocorticoid Receptors
Glucocorticoids
Luciferases
Dexamethasone
5 Citations (Scopus)

Regulation of Na,K-ATPase Expression by Endothelin-1 in Transformed Human Ciliary Non-Pigmented Epithelial (HNPE) Cells

Krishnamoorthy, R., Prasanna, G., Dauphin, R., Hulet, C., Agarwal, N. & Yorio, T., 1 Jan 2003, In : Journal of Ocular Pharmacology and Therapeutics. 19, 5, p. 465-481 17 p.

Research output: Contribution to journalArticle

Endothelin-1
Epithelial Cells
Monensin
Aqueous Humor
Ouabain
4 Citations (Scopus)

Reversal of galactosemic-induced inhibition of PGH synthase activity in cultured Lens epithelial cells

Cammarata, P. R., Jackson, T., Lou, M. & Yorio, T., 1 Jan 1989, In : Current Eye Research. 8, 10, p. 1063-1069 7 p.

Research output: Contribution to journalArticle

Prostaglandin-Endoperoxide Synthases
Galactose
Lenses
Epithelial Cells
Galactitol
14 Citations (Scopus)

Role of calcium and prostaglandins in the antidiuretic hormone response. Effect of ionophore A23187

Yorio, T., Henry, S. L., Hodges, D. H. & Caffrey, J. L., 15 Mar 1983, In : Biochemical Pharmacology. 32, 6, p. 1113-1118 6 p.

Research output: Contribution to journalArticle

Ionophores
Calcimycin
Vasopressins
Prostaglandins
Calcium

Role of icosanoids in transepithelial sodium transport

Yorio, T. & Benoit, P., 1 Jan 1984, In : Prostaglandins. 27, SUPPL. 1, 1 p.

Research output: Contribution to journalArticle

Eicosanoids
Sodium
2 Citations (Scopus)

Role of sodium on H+ excretion in the integument of the leopard frog Rana pipiens

Page, R., Frazier, L. W. & Yorio, T., 1 Jan 1988, In : Comparative Biochemistry and Physiology -- Part A: Physiology. 91, 1, p. 53-59 7 p.

Research output: Contribution to journalArticle

Rana pipiens
Acidosis
Anura
Sodium
Acids
34 Citations (Scopus)

Role of the ETB receptor in retinal ganglion cell death in glaucoma

Krishnamoorthy, R., Rao, V. R., Dauphin, R., Prasanna, G., Johnson, C. & Yorio, T., 1 Jun 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 6, p. 380-393 14 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Endothelin-1
Glaucoma
Cell Death
Apoptosis
4 Citations (Scopus)

Sigma-1 receptor regulates mitochondrial function in glucose-and oxygen-deprived retinal ganglion cells

Ellis, D. Z., Li, L., Park, Y., He, S., Mueller, B. & Yorio, T., May 2017, In : Investigative Ophthalmology and Visual Science. 58, 5, p. 2755-2764 10 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Oxygen
Glucose
Mitochondrial Membrane Potential
Electron Transport Complex IV
93 Citations (Scopus)

Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction

Tchedre, K. T., Huang, R-Q., Dibas, A., Krishnamoorthy, R., Dillon, G. H. & Yorio, T., 1 Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 4993-5002 10 p.

Research output: Contribution to journalArticle

Calcium Channels
Calcium
Potassium Chloride
Retinal Ganglion Cells
Homeostasis
34 Citations (Scopus)

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells

Mueller, B. H., Park, Y., Daudt, D. R., Ma, H. Y., Akopova, I., Stankowska, D. L., Clark, A. F. & Yorio, T., 1 Feb 2013, In : Experimental Eye Research. 107, p. 21-31 11 p.

Research output: Contribution to journalArticle

Retinal Ganglion Cells
Calcium Channels
Calcium
Calcium Channel Blockers
Ions
17 Citations (Scopus)

Sigma-1 receptor stimulation protects retinal ganglion cells from ischemia-like insult through the activation of extracellular-signal-regulated kinases 1/2

Mueller, B. H., Park, Y., Ma, H. Y., Dibas, A., Ellis, D. Z., Clark, A. & Yorio, T., 1 Nov 2014, In : Experimental Eye Research. 128, p. 156-169 14 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Retinal Ganglion Cells
Mitogen-Activated Protein Kinase 1
Ischemia
Pentazocine
19 Citations (Scopus)

Sorbinil prevents the galactose-induced inhibition of prostaglandin synthesis in lens cells

Cammarata, P. R., Jackson, T. & Yorio, T., 1 Jan 1988, In : Investigative Ophthalmology and Visual Science. 29, 9, p. 1452-1460 9 p.

Research output: Contribution to journalArticle

Prostaglandin-Endoperoxide Synthases
Galactose
Lenses
Prostaglandins
Aldehyde Reductase
13 Citations (Scopus)
Inositol
Phosphatidylinositols
Lenses
Galactose
Epithelial Cells
23 Citations (Scopus)
Spliceosomes
Trabecular Meshwork
Glucocorticoid Receptors
Glucocorticoids
Protein Isoforms
8 Citations (Scopus)

Stimulation of active Na transport by phospholipase C

Yorio, T. & Bentley, P. J., 1 Dec 1976, In : Nature. 261, 5562, p. 722-723 2 p.

Research output: Contribution to journalArticle

Active Biological Transport
Type C Phospholipases
Anura
Kidney Tubules
Skin
27 Citations (Scopus)

Stress-induced changes in neuronal Aquaporin-9 (AQP9) in a retinal ganglion cell-line

Dibas, A., Yang, M. H., Bobich, J. & Yorio, T., 1 May 2007, In : Pharmacological Research. 55, 5, p. 378-384 7 p.

Research output: Contribution to journalArticle

Aquaporins
Retinal Ganglion Cells
Cell Line
Real-Time Polymerase Chain Reaction
Osmotic Pressure
5 Citations (Scopus)

Surface membrane remodeling following removal of vasopressin in toad urinary bladder

Mia, A. J., Oakford, L. X. & Yorio, T., 1 Jan 1994, In : Tissue and Cell. 26, 2, p. 189-201 13 p.

Research output: Contribution to journalArticle

Vasopressins
Anura
Urinary Bladder
Membranes
Aquaporins
4 Citations (Scopus)

Targets of neuroprotection in glaucoma

He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. & Yorio, T., 1 Jan 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.

Research output: Contribution to journalArticle

Glaucoma
Retinal Diseases
Western World
Retinal Ganglion Cells
Aqueous Humor

The ATP-depleting reagent "iodacetamide" induces the degradation of protein kinase C alpha (PKCα) in LLC-PK1 pig kidney cells

Dibas, A., Mia, A. J. & Yorio, T., 1 Dec 1997, In : FASEB Journal. 11, 3

Research output: Contribution to journalArticle

Protein Kinase C-alpha
protein kinase C
kidney cells
Iodoacetamide
Swine
4 Citations (Scopus)

The ATP-depleting reagent iodoacetamide induces the degradation of protein kinase C alpha (PKCα) in LLC-PK1 pig kidney cells

Dibas, A., Wood, J., Mia, A. J. & Yorio, T., 19 Sep 1997, In : Life Sciences. 61, 17, p. 1697-1704 8 p.

Research output: Contribution to journalArticle

Iodoacetamide
Protein Kinase C-alpha
Swine
Adenosine Triphosphate
Kidney
14 Citations (Scopus)

The effects of elevated glucose on Na+/K+-ATPpase of cultured bovine retinal pigment epithelial cells measured by a new nonradioactive rubidium uptake assay

Crider, J. Y., Yorio, T., Sharif, N. A. & Griffin, B. W., 1 Jan 1997, In : Journal of Ocular Pharmacology and Therapeutics. 13, 4, p. 337-352 16 p.

Research output: Contribution to journalArticle

Rubidium
Retinal Pigments
Epithelial Cells
Hyperglycemia
Glucose
10 Citations (Scopus)

The effects of hyperosmotic agents on the electrical properties of the amphibian lens in vitro

Yorio, T. & Bentley, P. J., 1 Jan 1976, In : Experimental eye research. 22, 3, p. 195-208 14 p.

Research output: Contribution to journalArticle

Amphibians
Lenses
Mannitol
Ethanol
Epithelium
3 Citations (Scopus)

The effects of methylmercury compounds on the skin (in vitro) of the leopard frog (Rana pipiens)

Yorio, T. & Bentley, P. J., 1 Jan 1973, In : Comparative and General Pharmacology. 4, 14, p. 167-174 8 p.

Research output: Contribution to journalArticle

Methylmercury Compounds
Rana pipiens
Skin
Methyl Chloride
Vasotocin
16 Citations (Scopus)

The mode of action of bumetanide: Inhibition of chloride transport across the amphibian cornea

McGahan, M. C., Yorio, T. & Bentley, P. J., 1 Dec 1977, In : Journal of Pharmacology and Experimental Therapeutics. 203, 1, p. 97-102 6 p.

Research output: Contribution to journalArticle

Bumetanide
Furosemide
Amphibians
Cornea
Chlorides
14 Citations (Scopus)

The passive permeability of the skin of anuran amphibia: a comparison of frogs (Rana pipiens) and toads (Bufo marinus).

Bentley, P. J. & Yorio, T., 1 Oct 1976, In : The Journal of Physiology. 261, 3, p. 603-615 13 p.

Research output: Contribution to journalArticle

Bufo marinus
Rana pipiens
Amphibians
Anura
Permeability
8 Citations (Scopus)

The permeability of the skin of a neotenous urodele amphibian, the mudpuppy Necturus maculosus.

Bentley, P. J. & Yorio, T., 1 Feb 1977, In : The Journal of Physiology. 265, 2, p. 537-547 11 p.

Research output: Contribution to journalArticle

Necturus maculosus
Necturus
Amphibians
Ouabain
Permeability
14 Citations (Scopus)

The permeability of the skin of the aquatic anuran Xenopus laevis (Pipidae).

Yorio, T. & Bentley, P. J., 1 Feb 1978, In : Journal of Experimental Biology. 72, p. 285-289 5 p.

Research output: Contribution to journalArticle

Pipidae
Xenopus laevis
vasotocin
skin (animal)
Vasotocin
8 Citations (Scopus)

The properties of "active" Cl transport across the cornea of the toad Bufo marinus

Bentley, P. J. & Yorio, T., 1 Jan 1978, In : Comparative Biochemistry and Physiology -- Part A: Physiology. 61, 4, p. 635-641 7 p.

Research output: Contribution to journalArticle

Bufo marinus
Active Biological Transport
Anura
Cornea
Ouabain
94 Citations (Scopus)

The role of glia, mitochondria, and the immune system in glaucoma

Tezel, G., Ben-Hur, T., Gibson, G. E., Stevens, B., Streit, W. J., Wekerle, H., Bhattacharya, S. K., Borras, T., Burgoyne, C. F., Caspi, R. R., Chauhan, B. C., Clark, A., Crowston, J., Danias, J., Dick, A. D., Flammer, J., Foster, C. S., Grosskreutz, C. L., Grus, F. H., Guy, J. & 48 others, Hernandez, M. R., Johnson, E., Kaplan, H. J., Kuehn, M. H., Lenaers, G., Levin, L. A., Lindsey, J. D., Malina, H., Nickells, R. W., Osborne, N., Quigley, H. A., Rao, N., Rosenbaum, J. T., Sadun, A. A., Schwartz, M., Sun, D., Trounce, I., Wax, M. B., Yorio, T., Abrams, G. W., Atherton, S. S., Boatright, J. H., Chu, J., Dowling, J., Ferris, F. L., Garway-Heath, D., Gregory, M., Grzybowski, D. M., Gupta, N., Inman, D. M., Ju, W. K., Kang, K. D., Kaufman, H. E., Kaufman, P. L., Larssen, L. I., Liebmann, J., Lupien, C., Miller, R. F., Niesman, M., O'Brien, C., Petrash, J. M., Prasanna, G., Ritch, R., Shestopalov, V., Wirostko, B., WoldeMussie, E., Yue, B. & Zimmerman, T. J., 1 Mar 2009, In : Investigative Ophthalmology and Visual Science. 50, 3, p. 1001-1012 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Thrombin-induced endothelin-1 synthesis and secretion in retinal pigment epithelial cells is Rho kinase dependent

Narayan, S., Prasanna, G., Tchedre, K., Krishnamoorthy, R. & Yorio, T., 1 Oct 2010, In : Journal of Ocular Pharmacology and Therapeutics. 26, 5, p. 389-397 9 p.

Research output: Contribution to journalArticle

rho-Associated Kinases
Retinal Pigments
Endothelin-1
Thrombin
Epithelial Cells
2 Citations (Scopus)
Second Messenger Systems
Protein Kinases
Phospholipids
Protein Isoforms
Tumor Necrosis Factor-alpha