Research Output per year
Research Output 1973 2019
- 1 - 50 out of 152 results
- Publication Year, Title (descending)
Hybrid compound sa-2 is neuroprotective in animal models of retinal ganglion cell death
Stankowska, D. L., Dibas, A., Li, L., Zhang, W., Krishnamoorthy, V. R., Chavala, S. H., Nguyen, T. P., Yorio, T., Ellis, D. Z. & Acharya, S., Jul 2019, In : Investigative Ophthalmology and Visual Science. 60, 8, p. 3064-3073 10 p.Research output: Contribution to journal › Article
Neuroprotective Effects of Psalmotoxin-1, an Acid-Sensing Ion Channel (ASIC) Inhibitor, in Ischemia Reperfusion in Mouse Eyes
Dibas, A., Millar, J. C., Al-Farra, A. & Yorio, T., 3 Jul 2018, In : Current Eye Research. 43, 7, p. 921-933 13 p.Research output: Contribution to journal › Article
Targets of neuroprotection in glaucoma
He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. & Yorio, T., 1 Jan 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.Research output: Contribution to journal › Article
A feed-forward regulation of endothelin receptors by c-Jun in human non-pigmented ciliary epithelial cells and retinal ganglion cells
Wang, J., Ma, H. Y., Krishnamoorthy, R. R., Yorio, T. & He, S., Sep 2017, In : PLoS ONE. 12, 9, e0185390.Research output: Contribution to journal › Article
Sigma-1 receptor regulates mitochondrial function in glucose-and oxygen-deprived retinal ganglion cells
Ellis, D. Z., Li, L., Park, Y., He, S., Mueller, B. & Yorio, T., May 2017, In : Investigative Ophthalmology and Visual Science. 58, 5, p. 2755-2764 10 p.Research output: Contribution to journal › Article
Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy
Acharya, S., Rogers, P., Krishnamoorthy, R., Stankowska, D. L., Dias, H. V. R. & Yorio, T., 1 Mar 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 5, p. 1490-1494 5 p.Research output: Contribution to journal › Article
Glucocorticoid therapy and ocular hypertension
Dibas, A. & Yorio, T., 1 Jan 2016, In : European Journal of Pharmacology. 787, p. 57-71 15 p.Research output: Contribution to journal › Article
Involvement of ampa receptor and its flip and flop isoforms in retinal ganglion cell death following oxygen/glucose deprivation
Park, Y. H., Broyles, H. V., He, S., McGrady, N. R., Li, L. & Yorio, T., 1 Feb 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 508-526 19 p.Research output: Contribution to journal › Article
AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells
Park, Y. H., Mueller, B. H., McGrady, N. R., Ma, H. Y. & Yorio, T., 1 Mar 2015, In : Experimental eye research. 132, p. 136-150 15 p.Research output: Contribution to journal › Article
Endothelin-mediated changes in gene expression in isolated purified rat retinal ganglion cells
He, S., Park, Y. H., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 10, p. 6144-6161 18 p.Research output: Contribution to journal › Article
Neuroprotective effects of transcription factor brn3b in an ocular hypertension rat model of glaucoma
Stankowska, D. L., Minton, A. Z., Rutledge, M. A., Mueller, B. H., Phatak, N. R., He, S., Ma, H. Y., Forster, M. J., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 2, p. 893-907 15 p.Research output: Contribution to journal › Article
Methylene blue promotes quiescence of rat neural progenitor cells
Xie, L., Choudhury, G. R., Wang, J., Park, Y., Liu, R., Yuan, F., Zhang, C. L., Yorio, T., Jin, K. & Yang, S., 7 Oct 2014, In : Frontiers in Cellular Neuroscience. 8, OCT, 315.Research output: Contribution to journal › Article
Sigma-1 receptor stimulation protects retinal ganglion cells from ischemia-like insult through the activation of extracellular-signal-regulated kinases 1/2
Mueller, B. H., Park, Y., Ma, H. Y., Dibas, A., Ellis, D. Z., Clark, A. & Yorio, T., 1 Nov 2014, In : Experimental Eye Research. 128, p. 156-169 14 p.Research output: Contribution to journal › Article
Effects of thailanstatins on glucocorticoid response in trabecular meshwork and steroid-induced glaucoma
Jain, A., Liu, X., Wordinger, R. J., Yorio, T., Cheng, Y. Q. & Clark, A. F., 10 May 2013, In : Investigative Ophthalmology and Visual Science. 54, 5, p. 3137-3142 6 p.Research output: Contribution to journal › Article
Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells
Mueller, B. H., Park, Y., Daudt, D. R., Ma, H. Y., Akopova, I., Stankowska, D. L., Clark, A. F. & Yorio, T., 1 Feb 2013, In : Experimental Eye Research. 107, p. 21-31 11 p.Research output: Contribution to journal › Article
Fluorescent protein-labeled glucocorticoid receptor alpha isoform trafficking in cultured human trabecular meshwork cells.
Dibas, A., Jiang, M., Fudala, R., Gryczynski, I., Gryczynski, Z., Clark, A. & Yorio, T., 1 Jan 2012, In : Investigative ophthalmology & visual science. 53, 6, p. 2938-2950 13 p.Research output: Contribution to journal › Article
Methylene blue protects primary rat retinal ganglion cells from cellular senescence
Daudt, D. R., Mueller, B., Park, Y. H., Wen, Y. & Yorio, T., 1 Jul 2012, In : Investigative Ophthalmology and Visual Science. 53, 8, p. 4657-4667 11 p.Research output: Contribution to journal › Article
Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells
Jain, A., Wordinger, R. J., Yorio, T. & Clark, A. F., 1 Feb 2012, In : Investigative Ophthalmology and Visual Science. 53, 2, p. 857-866 10 p.Research output: Contribution to journal › Article
Endothelin, astrocytes and glaucoma
Prasanna, G., Krishnamoorthy, R. & Yorio, T., 1 Aug 2011, In : Experimental eye research. 93, 2, p. 170-177 8 p.Research output: Contribution to journal › Article
FKBP51 protects 661w cell culture from staurosporine-induced apoptosis
Daudt, D. R. & Yorio, T., 30 May 2011, In : Molecular Vision. 17, p. 1172-1181 10 p.Research output: Contribution to journal › Article
Perfusion-cultured bovine anterior segments as an ex vivo model for studying glucocorticoid-induced ocular hypertension and glaucoma
Mao, W., Tovar-Vidales, T., Yorio, T., Wordinger, R. J. & Clark, A. F., 1 Oct 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8068-8075 8 p.Research output: Contribution to journal › Article
Protein Profiling of human nonpigmented ciliary epithelium cell secretome: The differentiation factors characterization for retinal ganglion cell line
Chung, T. W., Yang, M. H., Krishnamoorthy, R., Jong, S. B., Chu, P. Y., Yang, Y. H., Chen, W. C., Chen, S. C. J., Dibas, A., Yorio, T. & Tyan, Y. C., 12 Oct 2011, In : Journal of Biomedicine and Biotechnology. 2011, 901329.Research output: Contribution to journal › Article
Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders
Fingert, J. H., Alward, W. L., Wang, K., Yorio, T. & Clark, A. F., 23 Aug 2010, In : Molecular Vision. 16, p. 596-601 6 p.Research output: Contribution to journal › Article
Canonical Transient Receptor Potential 6 (TRPC6), a redox-regulated cation channel
Graham, S., Ding, M., Ding, Y., Sours-Brothers, S., Luchowski, R., Gryczynski, Z., Yorio, T., Ma, H. & Ma, R., 23 Jul 2010, In : Journal of Biological Chemistry. 285, 30, p. 23466-23476 11 p.Research output: Contribution to journal › Article
Changes in ocular aquaporin expression following optic nerve crush
Dibas, A., Oku, H., Fukuhara, M., Kurimoto, T., Ikeda, T., Patil, R. V., Sharif, N. A. & Yorio, T., 20 Aug 2010, In : Molecular Vision. 16, p. 330-340 11 p.Research output: Contribution to journal › Article
Thrombin-induced endothelin-1 synthesis and secretion in retinal pigment epithelial cells is Rho kinase dependent
Narayan, S., Prasanna, G., Tchedre, K., Krishnamoorthy, R. & Yorio, T., 1 Oct 2010, In : Journal of Ocular Pharmacology and Therapeutics. 26, 5, p. 389-397 9 p.Research output: Contribution to journal › Article
The role of glia, mitochondria, and the immune system in glaucoma
Tezel, G., Ben-Hur, T., Gibson, G. E., Stevens, B., Streit, W. J., Wekerle, H., Bhattacharya, S. K., Borras, T., Burgoyne, C. F., Caspi, R. R., Chauhan, B. C., Clark, A. F., Crowston, J., Danias, J., Dick, A. D., Flammer, J., Foster, C. S., Grosskreutz, C. L., Grus, F. H., Guy, J. & 48 others, , 1 Mar 2009, In : Investigative Ophthalmology and Visual Science. 50, 3, p. 1001-1012 12 p.Research output: Contribution to journal › Article
Changes in ocular aquaporin-4 (AQP4) expression following retinal injury
Dibas, A., Yang, M. H., He, S., Bobich, J. & Yorio, T., 1 Jan 2008, In : Molecular Vision. 14, p. 1770-1783 14 p.Research output: Contribution to journal › Article
Drug delivery to posterior intraocular tissues: Third annual ARVO/Pfizer ophthalmics research institute conference
Edelhauser, H. F., Boatright, J. H., Nickerson, J. M., Edelhauser, H. F., Abrams, G., Adamis, A., Aguirre, G. D., Ambati, J., Becerra, P., Behar-Cohen, F., Berglin, L., Bernstein, S., Boatright, J., Crouch, R., Freeman, W., Friedlander, M., Geroski, D., Grossniklaus, H., Heckenlively, J., Kempen, J. & 16 others, , 1 Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 4712-4720 9 p.Research output: Contribution to journal › Article
Endothelin-1 mediated regulation of extracellular matrix collagens in cells of human lamina cribrosa
Rao, V. R., Krishnamoorthy, R. R. & Yorio, T., 1 Jun 2008, In : Experimental eye research. 86, 6, p. 886-894 9 p.Research output: Contribution to journal › Article
FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor β and glucocorticoid responsiveness
Zhang, X., Clark, A. & Yorio, T., 1 Mar 2008, In : Investigative Ophthalmology and Visual Science. 49, 3, p. 1037-1047 11 p.Research output: Contribution to journal › Article
Role of the ETB receptor in retinal ganglion cell death in glaucoma
Krishnamoorthy, R., Rao, V. R., Dauphin, R., Prasanna, G., Johnson, C. & Yorio, T., 1 Jun 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 6, p. 380-393 14 p.Research output: Contribution to journal › Article
Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction
Tchedre, K. T., Huang, R-Q., Dibas, A., Krishnamoorthy, R., Dillon, G. H. & Yorio, T., 1 Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 4993-5002 10 p.Research output: Contribution to journal › Article
σ-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, bax levels, and caspase-3 activation
Tchedre, K. T. & Yorio, T., 1 Jun 2008, In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2577-2588 12 p.Research output: Contribution to journal › Article
Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor β
Zhang, X., Ognibene, C. M., Clark, A. & Yorio, T., 1 Feb 2007, In : Experimental Eye Research. 84, 2, p. 275-284 10 p.Research output: Contribution to journal › Article
Downregulation of TRPC6 protein expression by high glucose, a possible mechanism for the impaired Ca2+ signaling in glomerular mesangial cells in diabetes
Graham, S., Ding, M., Sours-Brothers, S., Yorio, T., Ma, J. X. & Ma, R., 1 Oct 2007, In : American Journal of Physiology - Renal Physiology. 293, 4, p. F1381-F1390Research output: Contribution to journal › Article
Endothelin-1, endothelin A and B receptor expression and their pharmacological properties in GFAP negative human lamina cribrosa cells
Rao, V. R., Krishnamoorthy, R. & Yorio, T., 1 Jun 2007, In : Experimental eye research. 84, 6, p. 1115-1124 10 p.Research output: Contribution to journal › Article
Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes
He, S., Prasanna, G. & Yorio, T., 1 Aug 2007, In : Investigative Ophthalmology and Visual Science. 48, 8, p. 3737-3745 9 p.Research output: Contribution to journal › Article
Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells
He, S., Dibas, A., Yorio, T. & Prasanna, G., 1 Mar 2007, In : Experimental Biology and Medicine. 232, 3, p. 370-384 15 p.Research output: Contribution to journal › Article
Stress-induced changes in neuronal Aquaporin-9 (AQP9) in a retinal ganglion cell-line
Dibas, A., Yang, M. H., Bobich, J. & Yorio, T., 1 May 2007, In : Pharmacological Research. 55, 5, p. 378-384 7 p.Research output: Contribution to journal › Article
Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor β
Zhang, X., Clark, A. & Yorio, T., 1 Feb 2006, In : Investigative Ophthalmology and Visual Science. 47, 2, p. 700-708 9 p.Research output: Contribution to journal › Article
Characterization of endothelin-converting enzyme activities in ARPE-19 cells, a human retinal pigmented epithelial cell line
Dibas, A., Prasanna, G. & Yorio, T., 1 Jun 2005, In : Journal of Ocular Pharmacology and Therapeutics. 21, 3, p. 196-204 9 p.Research output: Contribution to journal › Article
Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma
Prasanna, G., Hulet, C., Desai, D., Krishnamoorthy, R. R., Narayan, S., Brun, A. M., Suburo, A. M. & Yorio, T., 1 Jan 2005, In : Pharmacological Research. 51, 1, p. 41-50 10 p.Research output: Contribution to journal › Article
Endothelin-1 modulates anterograde fast axonal transport in the central nervous system
Stokely, M. E., Yorio, T. & King, M. A., 1 Mar 2005, In : Journal of Neuroscience Research. 79, 5, p. 598-607 10 p.Research output: Contribution to journal › Article
Localization of endothelin-converting enzyme in bovine optic nerve and retina
Dibas, A., Prasanna, G. & Yorio, T., 1 Aug 2005, In : Journal of Ocular Pharmacology and Therapeutics. 21, 4, p. 288-297 10 p.Research output: Contribution to journal › Article
Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-β
Zhang, X., Clark, A. F. & Yorio, T., 1 Dec 2005, In : Investigative Ophthalmology and Visual Science. 46, 12, p. 4607-4616 10 p.Research output: Contribution to journal › Article
Endothelin-1 distribution and basolateral secretion in the retinal pigment epithelium
Narayan, S., Brun, A. M. & Yorio, T., 1 Jul 2004, In : Experimental eye research. 79, 1, p. 11-19 9 p.Research output: Contribution to journal › Article
Hypoxia augments TNF-α-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes
Desai, D., He, S., Yorio, T., Krishnamoorthy, R. & Prasanna, G., 4 Jun 2004, In : Biochemical and Biophysical Research Communications. 318, 3, p. 642-648 7 p.Research output: Contribution to journal › Article
Dexamethasone regulates endothelin-1 and endothelin receptors in human non-pigmented ciliary epithelial (HNPE) cells
Zhang, X., Krishnamoorthy, R., Prasanna, G., Narayan, S., Clark, A. & Yorio, T., 1 Mar 2003, In : Experimental eye research. 76, 3, p. 261-272 12 p.Research output: Contribution to journal › Article
Endothelin-1 Synthesis and Secretion in Human Retinal Pigment Epithelial Cells (ARPE-19): Differential Regulation by Cholinergics and TNF-α
Narayan, S., Prasanna, G., Krishnamoorthy, R. R., Zhang, X. & Yorio, T., 1 Nov 2003, In : Investigative Ophthalmology and Visual Science. 44, 11, p. 4885-4894 10 p.Research output: Contribution to journal › Article