Thomas Yorio

2019

Hybrid compound sa-2 is neuroprotective in animal models of retinal ganglion cell death

Stankowska, D. L., Dibas, A., Li, L., Zhang, W., Krishnamoorthy, V. R., Chavala, S. H., Nguyen, T. P., Yorio, T., Ellis, D. Z. & Acharya, S., Jul 2019, In : Investigative Ophthalmology and Visual Science. 60, 8, p. 3064-3073 10 p.

Research output: Contribution to journal › Article

Open Access

Retinal Ganglion Cells

Cell Death

Nerve Crush

Animal Models

Retina

2018

4 Citations (Scopus)

Neuroprotective Effects of Psalmotoxin-1, an Acid-Sensing Ion Channel (ASIC) Inhibitor, in Ischemia Reperfusion in Mouse Eyes

Dibas, A., Millar, J. C., Al-Farra, A. & Yorio, T., 3 Jul 2018, In : Current Eye Research. 43, 7, p. 921-933 13 p.

Research output: Contribution to journal › Article

Acid Sensing Ion Channel Blockers

Retinal Ganglion Cells

Neuroprotective Agents

Reperfusion

Ischemia

5 Citations (Scopus)

Targets of neuroprotection in glaucoma

He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. & Yorio, T., 1 Jan 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.

Research output: Contribution to journal › Article

Glaucoma

Retinal Diseases

Western World

Retinal Ganglion Cells

Aqueous Humor

2017

A feed-forward regulation of endothelin receptors by c-Jun in human non-pigmented ciliary epithelial cells and retinal ganglion cells

Wang, J., Ma, H. Y., Krishnamoorthy, R. R., Yorio, T. & He, S., Sep 2017, In : PLoS ONE. 12, 9, e0185390.

Research output: Contribution to journal › Article

CCAAT-Enhancer-Binding Proteins

Endothelin Receptors

food law

endothelins

Endothelin B Receptors

6 Citations (Scopus)

Sigma-1 receptor regulates mitochondrial function in glucose-and oxygen-deprived retinal ganglion cells

Ellis, D. Z., Li, L., Park, Y., He, S., Mueller, B. & Yorio, T., May 2017, In : Investigative Ophthalmology and Visual Science. 58, 5, p. 2755-2764 10 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Oxygen

Glucose

Mitochondrial Membrane Potential

Electron Transport Complex IV

2016

5 Citations (Scopus)

Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy

Acharya, S., Rogers, P., Krishnamoorthy, R., Stankowska, D. L., Dias, H. V. R. & Yorio, T., 1 Mar 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 5, p. 1490-1494 5 p.

Research output: Contribution to journal › Article

Optic Nerve Diseases

Prodrugs

Optics

Photoreceptor Cells

Molecules

17 Citations (Scopus)

Glucocorticoid therapy and ocular hypertension

Dibas, A. & Yorio, T., 1 Jan 2016, In : European Journal of Pharmacology. 787, p. 57-71 15 p.

Research output: Contribution to journal › Article

Ocular Hypertension

Glucocorticoids

Macular Degeneration

Diabetic Retinopathy

Glaucoma

4 Citations (Scopus)

Involvement of ampa receptor and its flip and flop isoforms in retinal ganglion cell death following oxygen/glucose deprivation

Park, Y. H., Broyles, H. V., He, S., McGrady, N. R., Li, L. & Yorio, T., 1 Feb 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 508-526 19 p.

Research output: Contribution to journal › Article

AMPA Receptors

Retinal Ganglion Cells

Protein Isoforms

Cell Death

Oxygen

2015

11 Citations (Scopus)

AMPA receptor desensitization is the determinant of AMPA receptor mediated excitotoxicity in purified retinal ganglion cells

Park, Y. H., Mueller, B. H., McGrady, N. R., Ma, H. Y. & Yorio, T., 1 Mar 2015, In : Experimental eye research. 132, p. 136-150 15 p.

Research output: Contribution to journal › Article

AMPA Receptors

Retinal Ganglion Cells

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid

Caspase 7

Calcium

9 Citations (Scopus)

Endothelin-mediated changes in gene expression in isolated purified rat retinal ganglion cells

He, S., Park, Y. H., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 10, p. 6144-6161 18 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Endothelins

Gene Expression

Endothelin-1

Endothelin-2

10 Citations (Scopus)

Neuroprotective effects of transcription factor brn3b in an ocular hypertension rat model of glaucoma

Stankowska, D. L., Minton, A. Z., Rutledge, M. A., Mueller, B. H., Phatak, N. R., He, S., Ma, H. Y., Forster, M. J., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 2, p. 893-907 15 p.

Research output: Contribution to journal › Article

Ocular Hypertension

Neuroprotective Agents

Intraocular Pressure

Glaucoma

Transcription Factors

2014

4 Citations (Scopus)

Methylene blue promotes quiescence of rat neural progenitor cells

Xie, L., Choudhury, G. R., Wang, J., Park, Y., Liu, R., Yuan, F., Zhang, C. L., Yorio, T., Jin, K. & Yang, S., 7 Oct 2014, In : Frontiers in Cellular Neuroscience. 8, OCT, 315.

Research output: Contribution to journal › Article

Methylene Blue

Stem Cells

Intraventricular Infusions

Cyclins

Neural Stem Cells

17 Citations (Scopus)

Sigma-1 receptor stimulation protects retinal ganglion cells from ischemia-like insult through the activation of extracellular-signal-regulated kinases 1/2

Mueller, B. H., Park, Y., Ma, H. Y., Dibas, A., Ellis, D. Z., Clark, A. & Yorio, T., 1 Nov 2014, In : Experimental Eye Research. 128, p. 156-169 14 p.

Research output: Contribution to journal › Article

Mitogen-Activated Protein Kinase 3

Retinal Ganglion Cells

Mitogen-Activated Protein Kinase 1

Ischemia

Pentazocine

2013

10 Citations (Scopus)

Effects of thailanstatins on glucocorticoid response in trabecular meshwork and steroid-induced glaucoma

Jain, A., Liu, X., Wordinger, R. J., Yorio, T., Cheng, Y. Q. & Clark, A. F., 10 May 2013, In : Investigative Ophthalmology and Visual Science. 54, 5, p. 3137-3142 6 p.

Research output: Contribution to journal › Article

Trabecular Meshwork

Glaucoma

Glucocorticoids

Steroids

Intraocular Pressure

37 Citations (Scopus)

Sigma-1 receptor stimulation attenuates calcium influx through activated L-type Voltage Gated Calcium Channels in purified retinal ganglion cells

Mueller, B. H., Park, Y., Daudt, D. R., Ma, H. Y., Akopova, I., Stankowska, D. L., Clark, A. F. & Yorio, T., 1 Feb 2013, In : Experimental Eye Research. 107, p. 21-31 11 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Calcium Channels

Calcium

Calcium Channel Blockers

Ions

2012

3 Citations (Scopus)

Fluorescent protein-labeled glucocorticoid receptor alpha isoform trafficking in cultured human trabecular meshwork cells.

Dibas, A., Jiang, M., Fudala, R., Gryczynski, I., Gryczynski, Z., Clark, A. & Yorio, T., 1 Jan 2012, In : Investigative ophthalmology & visual science. 53, 6, p. 2938-2950 13 p.

Research output: Contribution to journal › Article

Trabecular Meshwork

Protein Isoforms

Dexamethasone

Proteins

tanespimycin

23 Citations (Scopus)

Methylene blue protects primary rat retinal ganglion cells from cellular senescence

Daudt, D. R., Mueller, B., Park, Y. H., Wen, Y. & Yorio, T., 1 Jul 2012, In : Investigative Ophthalmology and Visual Science. 53, 8, p. 4657-4667 11 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Cell Aging

Methylene Blue

Electron Transport Complex IV

Rotenone

24 Citations (Scopus)

Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells

Jain, A., Wordinger, R. J., Yorio, T. & Clark, A. F., 1 Feb 2012, In : Investigative Ophthalmology and Visual Science. 53, 2, p. 857-866 10 p.

Research output: Contribution to journal › Article

Spliceosomes

Trabecular Meshwork

Glucocorticoid Receptors

Glucocorticoids

Protein Isoforms

2011

44 Citations (Scopus)

Endothelin, astrocytes and glaucoma

Prasanna, G., Krishnamoorthy, R. & Yorio, T., 1 Aug 2011, In : Experimental eye research. 93, 2, p. 170-177 8 p.

Research output: Contribution to journal › Article

Endothelins

Astrocytes

Glaucoma

Gliosis

Central Nervous System

10 Citations (Scopus)

FKBP51 protects 661w cell culture from staurosporine-induced apoptosis

Daudt, D. R. & Yorio, T., 30 May 2011, In : Molecular Vision. 17, p. 1172-1181 10 p.

Research output: Contribution to journal › Article

Tacrolimus Binding Proteins

Staurosporine

Cell Culture Techniques

Tacrolimus

Apoptosis

27 Citations (Scopus)

Perfusion-cultured bovine anterior segments as an ex vivo model for studying glucocorticoid-induced ocular hypertension and glaucoma

Mao, W., Tovar-Vidales, T., Yorio, T., Wordinger, R. J. & Clark, A. F., 1 Oct 2011, In : Investigative Ophthalmology and Visual Science. 52, 11, p. 8068-8075 8 p.

Research output: Contribution to journal › Article

Ocular Hypertension

Glaucoma

Dexamethasone

Glucocorticoids

Perfusion

6 Citations (Scopus)

Protein Profiling of human nonpigmented ciliary epithelium cell secretome: The differentiation factors characterization for retinal ganglion cell line

Chung, T. W., Yang, M. H., Krishnamoorthy, R., Jong, S. B., Chu, P. Y., Yang, Y. H., Chen, W. C., Chen, S. C. J., Dibas, A., Yorio, T. & Tyan, Y. C., 12 Oct 2011, In : Journal of Biomedicine and Biotechnology. 2011, 901329.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Epithelium

Cell Line

Epithelial Cells

Proteins

2010

23 Citations (Scopus)

Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders

Fingert, J. H., Alward, W. L., Wang, K., Yorio, T. & Clark, A. F., 23 Aug 2010, In : Molecular Vision. 16, p. 596-601 6 p.

Research output: Contribution to journal › Article

Glucocorticoid Receptors

Single Nucleotide Polymorphism

Steroids

Glucocorticoids

Ocular Hypertension

56 Citations (Scopus)

Canonical Transient Receptor Potential 6 (TRPC6), a redox-regulated cation channel

Graham, S., Ding, M., Ding, Y., Sours-Brothers, S., Luchowski, R., Gryczynski, Z., Yorio, T., Ma, H. & Ma, R., 23 Jul 2010, In : Journal of Biological Chemistry. 285, 30, p. 23466-23476 11 p.

Research output: Contribution to journal › Article

Arginine Vasopressin

Oxidation-Reduction

Cations

Vasopressin Receptors

Ethylmaleimide

21 Citations (Scopus)

Changes in ocular aquaporin expression following optic nerve crush

Dibas, A., Oku, H., Fukuhara, M., Kurimoto, T., Ikeda, T., Patil, R. V., Sharif, N. A. & Yorio, T., 20 Aug 2010, In : Molecular Vision. 16, p. 330-340 11 p.

Research output: Contribution to journal › Article

Nerve Crush

Aquaporins

Optic Nerve

Retinal Ganglion Cells

Glial Fibrillary Acidic Protein

7 Citations (Scopus)

Thrombin-induced endothelin-1 synthesis and secretion in retinal pigment epithelial cells is Rho kinase dependent

Narayan, S., Prasanna, G., Tchedre, K., Krishnamoorthy, R. & Yorio, T., 1 Oct 2010, In : Journal of Ocular Pharmacology and Therapeutics. 26, 5, p. 389-397 9 p.

Research output: Contribution to journal › Article

rho-Associated Kinases

Retinal Pigments

Endothelin-1

Thrombin

Epithelial Cells

2009

96 Citations (Scopus)

The role of glia, mitochondria, and the immune system in glaucoma

Tezel, G., Ben-Hur, T., Gibson, G. E., Stevens, B., Streit, W. J., Wekerle, H., Bhattacharya, S. K., Borras, T., Burgoyne, C. F., Caspi, R. R., Chauhan, B. C., Clark, A. F., Crowston, J., Danias, J., Dick, A. D., Flammer, J., Foster, C. S., Grosskreutz, C. L., Grus, F. H., Guy, J. & 48 others, Hernandez, M. R., Johnson, E., Kaplan, H. J., Kuehn, M. H., Lenaers, G., Levin, L. A., Lindsey, J. D., Malina, H., Nickells, R. W., Osborne, N., Quigley, H. A., Rao, N., Rosenbaum, J. T., Sadun, A. A., Schwartz, M., Sun, D., Trounce, I., Wax, M. B., Yorio, T., Abrams, G. W., Atherton, S. S., Boatright, J. H., Chu, J., Dowling, J., Ferris, F. L., Garway-Heath, D., Gregory, M., Grzybowski, D. M., Gupta, N., Inman, D., Ju, W. K., Kang, K. D., Kaufman, H. E., Kaufman, P. L., Larssen, L. I., Liebmann, J., Lupien, C., Miller, R. F., Niesman, M., O'Brien, C., Petrash, J. M., Prasanna, G., Ritch, R., Shestopalov, V., Wirostko, B., WoldeMussie, E., Yue, B. & Zimmerman, T. J., 1 Mar 2009, In : Investigative Ophthalmology and Visual Science. 50, 3, p. 1001-1012 12 p.

Research output: Contribution to journal › Article

2008

30 Citations (Scopus)

Changes in ocular aquaporin-4 (AQP4) expression following retinal injury

Dibas, A., Yang, M. H., He, S., Bobich, J. & Yorio, T., 1 Jan 2008, In : Molecular Vision. 14, p. 1770-1783 14 p.

Research output: Contribution to journal › Article

Aquaporin 4

Ubiquitination

Intraocular Pressure

Wounds and Injuries

Glial Fibrillary Acidic Protein

10 Citations (Scopus)

Drug delivery to posterior intraocular tissues: Third annual ARVO/Pfizer ophthalmics research institute conference

Edelhauser, H. F., Boatright, J. H., Nickerson, J. M., Edelhauser, H. F., Abrams, G., Adamis, A., Aguirre, G. D., Ambati, J., Becerra, P., Behar-Cohen, F., Berglin, L., Bernstein, S., Boatright, J., Crouch, R., Freeman, W., Friedlander, M., Geroski, D., Grossniklaus, H., Heckenlively, J., Kempen, J. & 16 others, Kompella, U., Laties, A., LaVail, M., McGinnis, J., Marc, R., Miller, J., Nickerson, J., O'Brien, J., Olsen, T., Palanker, D., Robinson, M., Saperstein, D., Sternberg, P., Stout, J. T., Williams, G. & Yorio, T., 1 Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 4712-4720 9 p.

Research output: Contribution to journal › Article

20 Citations (Scopus)

Endothelin-1 mediated regulation of extracellular matrix collagens in cells of human lamina cribrosa

Rao, V. R., Krishnamoorthy, R. R. & Yorio, T., 1 Jun 2008, In : Experimental eye research. 86, 6, p. 886-894 9 p.

Research output: Contribution to journal › Article

Endothelin-1

Extracellular Matrix

Collagen

Collagen Type I

Collagen Type VI

75 Citations (Scopus)

FK506-binding protein 51 regulates nuclear transport of the glucocorticoid receptor β and glucocorticoid responsiveness

Zhang, X., Clark, A. & Yorio, T., 1 Mar 2008, In : Investigative Ophthalmology and Visual Science. 49, 3, p. 1037-1047 11 p.

Research output: Contribution to journal › Article

Tacrolimus Binding Proteins

Cell Nucleus Active Transport

Glucocorticoid Receptors

Dexamethasone

Glucocorticoids

35 Citations (Scopus)

Role of the ET_B receptor in retinal ganglion cell death in glaucoma

Krishnamoorthy, R., Rao, V. R., Dauphin, R., Prasanna, G., Johnson, C. & Yorio, T., 1 Jun 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 6, p. 380-393 14 p.

Research output: Contribution to journal › Article

Retinal Ganglion Cells

Endothelin-1

Glaucoma

Cell Death

Apoptosis

95 Citations (Scopus)

Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction

Tchedre, K. T., Huang, R-Q., Dibas, A., Krishnamoorthy, R., Dillon, G. H. & Yorio, T., 1 Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 4993-5002 10 p.

Research output: Contribution to journal › Article

Calcium Channels

Calcium

Potassium Chloride

Retinal Ganglion Cells

Homeostasis

70 Citations (Scopus)

σ-1 receptors protect RGC-5 cells from apoptosis by regulating intracellular calcium, bax levels, and caspase-3 activation

Tchedre, K. T. & Yorio, T., 1 Jun 2008, In : Investigative Ophthalmology and Visual Science. 49, 6, p. 2577-2588 12 p.

Research output: Contribution to journal › Article

Caspase 3

Glutamic Acid

Apoptosis

Calcium

Cell Death

2007

82 Citations (Scopus)

Dexamethasone inhibition of trabecular meshwork cell phagocytosis and its modulation by glucocorticoid receptor β

Zhang, X., Ognibene, C. M., Clark, A. & Yorio, T., 1 Feb 2007, In : Experimental Eye Research. 84, 2, p. 275-284 10 p.

Research output: Contribution to journal › Article

Trabecular Meshwork

Cytophagocytosis

Glucocorticoid Receptors

Dexamethasone

Glucocorticoids

64 Citations (Scopus)

Downregulation of TRPC6 protein expression by high glucose, a possible mechanism for the impaired Ca²⁺ signaling in glomerular mesangial cells in diabetes

Graham, S., Ding, M., Sours-Brothers, S., Yorio, T., Ma, J. X. & Ma, R., 1 Oct 2007, In : American Journal of Physiology - Renal Physiology. 293, 4, p. F1381-F1390

Research output: Contribution to journal › Article

Mesangial Cells

Down-Regulation

Glucose

Angiotensin II

Proteins

16 Citations (Scopus)

Endothelin-1, endothelin A and B receptor expression and their pharmacological properties in GFAP negative human lamina cribrosa cells

Rao, V. R., Krishnamoorthy, R. & Yorio, T., 1 Jun 2007, In : Experimental eye research. 84, 6, p. 1115-1124 10 p.

Research output: Contribution to journal › Article

Endothelin B Receptors

Endothelin A Receptors

Endothelin-1

Pharmacology

Optic Nerve Diseases

54 Citations (Scopus)

Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes

He, S., Prasanna, G. & Yorio, T., 1 Aug 2007, In : Investigative Ophthalmology and Visual Science. 48, 8, p. 3737-3745 9 p.

Research output: Contribution to journal › Article

Tissue Inhibitor of Metalloproteinases

Matrix Metalloproteinase Inhibitors

Endothelin-1

Matrix Metalloproteinases

Astrocytes

10 Citations (Scopus)

Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells

He, S., Dibas, A., Yorio, T. & Prasanna, G., 1 Mar 2007, In : Experimental Biology and Medicine. 232, 3, p. 370-384 15 p.

Research output: Contribution to journal › Article

Astrocytoma

Endothelin-1

Phosphorylation

Cell proliferation

Mitogen-Activated Protein Kinases

27 Citations (Scopus)

Stress-induced changes in neuronal Aquaporin-9 (AQP9) in a retinal ganglion cell-line

Dibas, A., Yang, M. H., Bobich, J. & Yorio, T., 1 May 2007, In : Pharmacological Research. 55, 5, p. 378-384 7 p.

Research output: Contribution to journal › Article

Aquaporins

Retinal Ganglion Cells

Cell Line

Real-Time Polymerase Chain Reaction

Osmotic Pressure

2006

25 Citations (Scopus)

Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor β

Zhang, X., Clark, A. & Yorio, T., 1 Feb 2006, In : Investigative Ophthalmology and Visual Science. 47, 2, p. 700-708 9 p.

Research output: Contribution to journal › Article

HSP90 Heat-Shock Proteins

Molecular Chaperones

Cell Nucleus Active Transport

Glucocorticoid Receptors

tanespimycin

2005

3 Citations (Scopus)

Characterization of endothelin-converting enzyme activities in ARPE-19 cells, a human retinal pigmented epithelial cell line

Dibas, A., Prasanna, G. & Yorio, T., 1 Jun 2005, In : Journal of Ocular Pharmacology and Therapeutics. 21, 3, p. 196-204 9 p.

Research output: Contribution to journal › Article

Endothelin-1

Epithelial Cells

Cell Line

Cathepsins

Cell Membrane

75 Citations (Scopus)

Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma

Prasanna, G., Hulet, C., Desai, D., Krishnamoorthy, R. R., Narayan, S., Brun, A. M., Suburo, A. M. & Yorio, T., 1 Jan 2005, In : Pharmacological Research. 51, 1, p. 41-50 10 p.

Research output: Contribution to journal › Article

Endothelin-1

Intraocular Pressure

Glaucoma

Optic Disk

Optic Nerve

28 Citations (Scopus)

Endothelin-1 modulates anterograde fast axonal transport in the central nervous system

Stokely, M. E., Yorio, T. & King, M. A., 1 Mar 2005, In : Journal of Neuroscience Research. 79, 5, p. 598-607 10 p.

Research output: Contribution to journal › Article

Axonal Transport

Endothelin-1

Central Nervous System

Nerve Tissue

Endothelins

8 Citations (Scopus)

Localization of endothelin-converting enzyme in bovine optic nerve and retina

Dibas, A., Prasanna, G. & Yorio, T., 1 Aug 2005, In : Journal of Ocular Pharmacology and Therapeutics. 21, 4, p. 288-297 10 p.

Research output: Contribution to journal › Article

Endothelin-1

Optic Nerve

Retina

Cathepsins

Cell Membrane

54 Citations (Scopus)

Regulation of glucocorticoid responsiveness in glaucomatous trabecular meshwork cells by glucocorticoid receptor-β

Zhang, X., Clark, A. F. & Yorio, T., 1 Dec 2005, In : Investigative Ophthalmology and Visual Science. 46, 12, p. 4607-4616 10 p.

Research output: Contribution to journal › Article

Trabecular Meshwork

Glucocorticoid Receptors

Glucocorticoids

Luciferases

Dexamethasone

2004

21 Citations (Scopus)

Endothelin-1 distribution and basolateral secretion in the retinal pigment epithelium

Narayan, S., Brun, A. M. & Yorio, T., 1 Jul 2004, In : Experimental eye research. 79, 1, p. 11-19 9 p.

Research output: Contribution to journal › Article

Retinal Pigment Epithelium

Endothelin-1

Retinal Vessels

Retinal Pigments

Endothelins

43 Citations (Scopus)

Hypoxia augments TNF-α-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes

Desai, D., He, S., Yorio, T., Krishnamoorthy, R. & Prasanna, G., 4 Jun 2004, In : Biochemical and Biophysical Research Communications. 318, 3, p. 642-648 7 p.

Research output: Contribution to journal › Article

Optic Disk

Cell proliferation

Endothelin-1

Astrocytes

Optics

2003

25 Citations (Scopus)

Dexamethasone regulates endothelin-1 and endothelin receptors in human non-pigmented ciliary epithelial (HNPE) cells

Zhang, X., Krishnamoorthy, R., Prasanna, G., Narayan, S., Clark, A. & Yorio, T., 1 Mar 2003, In : Experimental eye research. 76, 3, p. 261-272 12 p.

Research output: Contribution to journal › Article

Endothelin A Receptors

Endothelin Receptors

Dexamethasone

Endothelin B Receptors

Endothelin-1

48 Citations (Scopus)

Endothelin-1 Synthesis and Secretion in Human Retinal Pigment Epithelial Cells (ARPE-19): Differential Regulation by Cholinergics and TNF-α

Narayan, S., Prasanna, G., Krishnamoorthy, R. R., Zhang, X. & Yorio, T., 1 Nov 2003, In : Investigative Ophthalmology and Visual Science. 44, 11, p. 4885-4894 10 p.

Research output: Contribution to journal › Article

Retinal Pigments

Endothelin-1

Cholinergic Agents

Epithelial Cells

Retinal Pigment Epithelium

Thomas Yorio, PhD