Projects per year
Personal profile
Area of Expertise
My laboratory studies the role of the central nervous system in the regulation of the cardiovascular system, and water and electrolyte balance. We study how the brain participates in the normal maintenance of blood pressure and fluid balance, a process called homeostasis. We also investigate how changes in these CNS processes contribute to water retention associated with heart or liver disease and chronic diseases such as hypertension. Our goal is to achieve a better understanding of how the CNS contributes to health and diseases though its interactions with the cardiovascular system.
Education/Academic qualification
BA in Psychology, Eastern Illinois University
MS in Biopsychology, University of Iowa
PhD in Biopsychology, University of Iowa
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Projects
Roles of the CRH-containing Projections from the PVN to the NTS in the Sleep Apnea Induced Hypertension (For: Lei Wang)
Mifflin, S. & Cunningham, T.
1/07/18 → 30/06/20
Project: Research
Central Mechanisms and Novel BioMarkers of the Salt-Sensitivity of Blood Pressure
1/05/18 → 28/02/22
Project: Research
Neural Regulation of Vasopresson Release in a model of Dilutaional Hyponatremia
Cunningham, T. & Cunningham, R.
NHLBI: Nat Heart, Lung & Blood Institute
15/04/18 → 31/03/22
Project: Research
Texas Minority Health, Education, Research, and Outreach (Texas MiHERO)
Vishwanatha, J., Knebl, J., Raines-Milenkov, A., Cunningham, T., He, J., Spence-Almaguer, E., Clay, P. & Basha, R.
NIMHD: Natl Institute on Minority Health
14/09/17 → 30/06/22
Project: Research
Research Output
Brain-Derived Neurotrophic Factor and Supraoptic Vasopressin Neurons in Hyponatremia
Balapattabi, K., Little, J. T., Bachelor, M. & Cunningham, J. T., 1 Jul 2020, In : Neuroendocrinology. 110, 7-8, p. 630-641 12 p.Research output: Contribution to journal › Article
Open Access
Caspase lesions of PVN-projecting MnPO neurons block the sustained component of CIH-induced hypertension in adult male rats
Marciante, A. B., Wang, L. A., Little, J. T. & Cunningham, J. T., 1 Jan 2020, In : American Journal of Physiology - Heart and Circulatory Physiology. 318, 1, p. H34-H48Research output: Contribution to journal › Review article
1
Scopus
citations
Estrogen receptor involvement in vascular cognitive impairment and vascular dementia pathogenesis and treatment
Nguyen, D. H., Cunningham, J. T. & Sumien, N., 2020, (Accepted/In press) In : GeroScience.Research output: Contribution to journal › Review article
Hypothalamic paraventricular nucleus Gαi2 (guanine nucleotide-binding protein alpha inhibiting activity polypeptide 2) protein-mediated neural control of the kidney and the salt sensitivity of blood pressure
Carmichael, C. Y., Kuwabara, J. T., Pascale, C. L., Moreira, J. D., Mahne, S. E., Kapusta, D. R., Rosene, D. L., Williams, J. S., Thomas Cunningham, J. & Wainford, R. D., 1 Apr 2020, In : Hypertension. p. 1002-1011 10 p.Research output: Contribution to journal › Article
1
Scopus
citations
Angiotensin type 1a receptors in the median preoptic nucleus support intermittent hypoxia-induced hypertension
Shell, B., Farmer, G. E., Nedungadi, T. P., Wang, L. A., Marciante, A. B., Snyder, B., Cunningham, R. L. & Cunningham, J. T., 1 May 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 5, p. R651-R665Research output: Contribution to journal › Article
5
Scopus
citations