Projects per year
Personal profile
Area of Expertise
My laboratory studies the role of the central nervous system in the regulation of the cardiovascular system, and water and electrolyte balance. We study how the brain participates in the normal maintenance of blood pressure and fluid balance, a process called homeostasis. We also investigate how changes in these CNS processes contribute to water retention associated with heart or liver disease and chronic diseases such as hypertension. Our goal is to achieve a better understanding of how the CNS contributes to health and diseases though its interactions with the cardiovascular system.
Education/Academic qualification
PhD in Biopsychology, University of Iowa
MS in Biopsychology, University of Iowa
BA in Psychology, Eastern Illinois University
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- 6 Similar Profiles
Supraoptic Nucleus
Medicine & Life Sciences
Vasopressins
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Pressoreceptors
Medicine & Life Sciences
Paraventricular Hypothalamic Nucleus
Medicine & Life Sciences
Preoptic Area
Medicine & Life Sciences
Angiotensin II
Medicine & Life Sciences
Solitary Nucleus
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2012 2022
Roles of the CRH-containing Projections from the PVN to the NTS in the Sleep Apnea Induced Hypertension (For: Lei Wang)
Mifflin, S. & Cunningham, T.
1/07/18 → 30/06/20
Project: Research
Central Mechanisms and Novel BioMarkers of the Salt-Sensitivity of Blood Pressure
1/05/18 → 28/02/22
Project: Research
Neural Regulation of Vasopresson Release in a model of Dilutaional Hyponatremia
Cunningham, T., Cunningham, R. & Yuan, J.
NHLBI: Nat Heart, Lung & Blood Institute
15/04/18 → 31/03/22
Project: Research
Research Output 1985 2019
Angiotensin type 1a receptors in the median preoptic nucleus support intermittent hypoxia-induced hypertension
Shell, B., Farmer, G. E., Nedungadi, T. P., Wang, L. A., Marciante, A. B., Snyder, B., Cunningham, R. L. & Cunningham, J. T., 1 May 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 5, p. R651-R665Research output: Contribution to journal › Article › Research › peer-review
Angiotensin Type 1 Receptor
Preoptic Area
Hypertension
Small Interfering RNA
Angiotensins
Effects of salt-loading on supraoptic vasopressin neurones assessed by ClopHensorN chloride imaging
Balapattabi, K., Farmer, G. E., Knapp, B. A., Little, J. T., Bachelor, M., Yuan, J. P. & Cunningham, J. T., 1 Jan 2019, In : Journal of Neuroendocrinology. 31, 8, e12752.Research output: Contribution to journal › Article › Research › peer-review
Supraoptic Nucleus
Vasopressins
Chlorides
Arginine Vasopressin
Salts
Selectively inhibiting the median preoptic nucleus attenuates angiotensin II and hyperosmotic- induced drinking behavior and vasopressin release in adult male rats
Marciante, A. B., Wang, L. A., Farmer, G. E. & Cunningham, J. T., 1 Mar 2019, In : eNeuro. 6, 2, e0473-18.2019.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Drinking Behavior
Preoptic Area
Vasopressins
Angiotensin II
Designer Drugs
Sniffer cells for the detection of neural Angiotensin II in vitro
Farmer, G. E., Amune, A., Bachelor, M. E., Duong, P., Yuan, J. P. & Cunningham, J. T., 1 Dec 2019, In : Scientific Reports. 9, 1, 8820.Research output: Contribution to journal › Article › Research › peer-review
Open Access
Neuropeptides
Angiotensin II
Cultured Cells
Angiotensin III
Optogenetics
1
Citation
(Scopus)
AT1a influences GABAA-mediated inhibition through regulation of KCC2 expression
Farmer, G. E., Balapattabi, K., Bachelor, M. E., Little, J. T. & Cunningham, J. T., 1 Nov 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 5, p. R972-R982Research output: Contribution to journal › Article › Research › peer-review
Preoptic Area
Angiotensins
Angiotensin Type 1 Receptor
Neurons
Angiotensin II