Projects per year
Personal profile
Area of Expertise
My laboratory studies the role of the central nervous system in the regulation of the cardiovascular system, and water and electrolyte balance. We study how the brain participates in the normal maintenance of blood pressure and fluid balance, a process called homeostasis. We also investigate how changes in these CNS processes contribute to water retention associated with heart or liver disease and chronic diseases such as hypertension. Our goal is to achieve a better understanding of how the CNS contributes to health and diseases though its interactions with the cardiovascular system.
Education/Academic qualification
BA in Psychology, Eastern Illinois University
MS in Biopsychology, University of Iowa
PhD in Biopsychology, University of Iowa
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Projects
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Central Mechanisms and Novel BioMarkers of the Salt-Sensitivity of Blood Pressure
1/05/18 → 28/02/22
Project: Research
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Neural Regulation of Vasopresson Release in a model of Dilutaional Hyponatremia
Cunningham, T. & Cunningham, R.
NHLBI: Nat Heart, Lung & Blood Institute
15/04/18 → 31/03/22
Project: Research
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Texas Minority Health, Education, Research, and Outreach (Texas MiHERO)
Vishwanatha, J., Knebl, J., Raines-Milenkov, A., Cunningham, T., He, J., Spence-Almaguer, E., Clay, P. & Basha, R.
NIMHD: Natl Institute on Minority Health
14/09/17 → 30/06/22
Project: Research
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Promoting Diversity in Research Training for Health Professionals
Vishwanatha, J., Cunningham, T. & Schreihofer, A.
NHLBI: Nat Heart, Lung & Blood Institute
15/05/16 → 30/04/21
Project: Research
Research Output
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Brain-Derived Neurotrophic Factor and Supraoptic Vasopressin Neurons in Hyponatremia
Balapattabi, K., Little, J. T., Bachelor, M. & Cunningham, J. T., 1 Jul 2020, In: Neuroendocrinology. 110, 7-8, p. 630-641 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Caspase lesions of PVN-projecting MnPO neurons block the sustained component of CIH-induced hypertension in adult male rats
Marciante, A. B., Wang, L. A., Little, J. T. & Cunningham, J. T., 2020, In: American Journal of Physiology - Heart and Circulatory Physiology. 318, 1, p. H34-H48Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Estrogen receptor involvement in vascular cognitive impairment and vascular dementia pathogenesis and treatment
Nguyen, D. H., Cunningham, J. T. & Sumien, N., 2020, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Review article › peer-review
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Gq DREADD activation of CaMKIIa MnPO neurons stimulates nitric oxide activity
Marciante, A. B., Farmer, G. E. & Thomas Cunningham, J., 2020, In: Journal of Neurophysiology. 124, 2, p. 591-609 19 p.Research output: Contribution to journal › Article › peer-review
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Hypothalamic paraventricular nucleus Gαi2 (guanine nucleotide-binding protein alpha inhibiting activity polypeptide 2) protein-mediated neural control of the kidney and the salt sensitivity of blood pressure
Carmichael, C. Y., Kuwabara, J. T., Pascale, C. L., Moreira, J. D., Mahne, S. E., Kapusta, D. R., Rosene, D. L., Williams, J. S., Thomas Cunningham, J. & Wainford, R. D., 1 Apr 2020, In: Hypertension. p. 1002-1011 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations