Projects per year
Personal profile
Area of Expertise
My current research is focused on expanding the chemical toolbox for neural signaling and anti-inflammation/anti-oxidant pathways to help us understand the mechanism of action of the disease pathology associated with glaucomatous optic neuropathy, Alzheimer’s Diseases, Ischemic stroke, and angiogenesis. Our lab integrates medicinal chemistry, chemical biology, bio-engineering, and drug delivery using nanotechnology. We employ synthetic organic and organometallic chemistry to generate a small molecule library for low throughput as well as high throughput screening (target based as well as phenotypic). The ultimate goal of my lab is to produce novel therapeutic molecules which can be progressed to human clinical trials for these diseases.
Education/Academic qualification
PhD in Organic Chemistry, CSIR - Indian Institute of Chemical Technology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel Hybrid Molecule with Bot
Millar, C. (CoI) & Acharya, S. (PI)
1/03/20 → 31/08/26
Project: Research
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Sex differences in in vitro and in vivo glaucoma models may predict gender specific dose adjustment needs
Acharya, S. (PI)
1/03/20 → 31/08/25
Project: Research
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Bi-functional Molecule for Glaucomatous Optic Neuropathy
Acharya, S. (PI) & Stankowska, D. (CoI)
1/07/18 → 30/12/20
Project: Research
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Evaluation of small molecules in ocular neovascularization (For: Daniel Larson)
Acharya, S. (PI)
5/06/17 → 31/05/18
Project: Research
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Protocols for Access to and Dose Selection of Selected IOP-Lowering Drugs
Acharya, S. & Klimko, P. G., 1 Jan 2025, Research Protocols for Ophthalmic Disease Mechanisms and Therapeutics: Glaucoma-Ocular Hypertension. Bentham Science Publishers, p. 20-32 13 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Pulmonary and neurobehavioral efficacies of AVR-48, a TLR4 modulator, in a preterm lamb model of bronchopulmonary dysplasia
Acharya, S., Riley, D., Dayoub, A., Acharya, E., Rebentisch, A., Simmons, M., Bowen, S., Beachy, J., Dawson, E., Major, E., Borton, M., Van Boerum, J., Dahl, M. J., Bhandari, V., Kallapur, S. G., Christensen, D. J. & Albertine, K. H., Dec 2025, In: Respiratory Research. 26, 1, 261.Research output: Contribution to journal › Article › peer-review
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Novel Small Molecules with Anti-Inflammatory and Anti-Angiogenic Activity in a Mouse Model of Oxygen-Induced Retinopathy
Dayoub, A. S., Acharya, E., Dibas, A., Jones, H. P. & Acharya, S., Aug 2024, In: Cells. 13, 16, 1371.Research output: Contribution to journal › Article › peer-review
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Hybrid compound sa-2 is neuroprotective in animal models of retinal ganglion cell death
Stankowska, D. L., Dibas, A., Li, L., Zhang, W., Krishnamoorthy, V. R., Chavala, S. H., Nguyen, T. P., Yorio, T., Ellis, D. Z. & Acharya, S., Jul 2019, In: Investigative Ophthalmology and Visual Science. 60, 8, p. 3064-3073 10 p.Research output: Contribution to journal › Article › peer-review
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Optimized PLGA encapsulated SA-2 nanosuspension exhibits sustained intraocular pressure reduction in the mouse microbead occlusion model of ocular hypertension
Amankwa, C. E., DebNath, B., Pham, J. H., Johnson, G. A., Zhang, W., Ranjan, A., Stankowska, D. L. & Acharya, S., 1 Mar 2025, In: European Journal of Pharmaceutical Sciences. 206, 107016.Research output: Contribution to journal › Article › peer-review