Personal profile
Area of Expertise
My current research is focused on expanding the chemical toolbox for neural signaling and anti-inflammation/anti-oxidant pathways to help us understand the mechanism of action of the disease pathology associated with glaucomatous optic neuropathy, Alzheimer’s Diseases, Ischemic stroke, and angiogenesis. Our lab integrates medicinal chemistry, chemical biology, bio-engineering, and drug delivery using nanotechnology. We employ synthetic organic and organometallic chemistry to generate a small molecule library for low throughput as well as high throughput screening (target based as well as phenotypic). The ultimate goal of my lab is to produce novel therapeutic molecules which can be progressed to human clinical trials for these diseases.
Education/Academic qualification
PhD in Organic Chemistry, CSIR - Indian Institute of Chemical Technology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel Hybrid Molecule with Bot
Millar, C. (CoI) & Acharya, S. (PI)
1/03/20 → 31/08/26
Project: Research
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Sex differences in in vitro and in vivo glaucoma models may predict gender specific dose adjustment needs
Acharya, S. (PI)
1/03/20 → 31/08/25
Project: Research
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Bi-functional Molecule for Glaucomatous Optic Neuropathy
Acharya, S. (PI) & Stankowska, D. (CoI)
1/07/18 → 30/12/20
Project: Research
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Evaluation of small molecules in ocular neovascularization (For: Daniel Larson)
Acharya, S. (PI)
5/06/17 → 31/05/18
Project: Research
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Asymmetric synthesis of the stereoisomers of 11,12,15(S)-trihydroxyeicosa- 5(Z),8(Z),13(E)-trienoic acid, a potent endothelium-derived vasodilator
Falck, J. R., Barma, D., Mohapatra, S., Bandyopadhyay, A., Reddy, K. M., Qi, J. & Campbell, W., 4 Oct 2004, In: Bioorganic and Medicinal Chemistry Letters. 14, 19, p. 4987-4990 4 p.Research output: Contribution to journal › Article › peer-review
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Hybrid Nitric Oxide Donor and its Carrier for the Treatment of Peripheral Arterial Diseases
Le, D. Q., Kuriakose, A. E., Nguyen, D. X., Nguyen, K. T. & Acharya, S., 1 Dec 2017, In: Scientific Reports. 7, 1, 8692.Research output: Contribution to journal › Article › peer-review
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Identification of a Mammalian Long Chain Fatty Acyl Elongase Regulated by Sterol Regulatory Element-binding Proteins
Moon, Y. A., Shah, N. A., Mohapatra, S., Warrington, J. A. & Horton, J. D., 30 Nov 2001, In: Journal of Biological Chemistry. 276, 48, p. 45358-45366 9 p.Research output: Contribution to journal › Article › peer-review
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Neighbouring group assisted sulfonamide cleavage of sharpless aminols under acetonation conditions
Chandrasekhar, S. & Mohapatra, S., 12 Feb 1998, In: Tetrahedron Letters. 39, 7, p. 695-698 4 p.Research output: Contribution to journal › Article › peer-review
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Chiral α,β-Dialkoxy- and α-Alkoxy-β-aminostannanes: Preparation and Copper-Mediated Cross-Coupling
Mohapatra, S., Bandyopadhyay, A., Barma, D. K., Capdevila, J. H. & Falck, J. R., 11 Dec 2003, In: Organic Letters. 5, 25, p. 4759-4762 4 p.Research output: Contribution to journal › Article › peer-review