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Suchismita Acharya, PhD

  • 576 Citations
  • 10 h-Index
19962020

Research output per year

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Personal profile

Area of Expertise

My current research is focused on expanding the chemical toolbox for neural signaling and anti-inflammation/anti-oxidant pathways to help us understand the mechanism of action of the disease pathology associated with glaucomatous optic neuropathy, Alzheimer’s Diseases, Ischemic stroke, and angiogenesis. Our lab integrates medicinal chemistry, chemical biology, bio-engineering, and drug delivery using nanotechnology. We employ synthetic organic and organometallic chemistry to generate a small molecule library for low throughput as well as high throughput screening (target based as well as phenotypic). The ultimate goal of my lab is to produce novel therapeutic molecules which can be progressed to human clinical trials for these diseases.

Education/Academic qualification

PhD in Organic Chemistry, CSIR Indian Institute of Chemical Technology

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Projects

Bi-functional Molecule for Glaucomatous Optic Neuropathy

Acharya, S. & Stankowska, D.

BrightFocus Foundation

1/07/18 → 30/06/20

Project: Research

Evaluation of small molecules in ocular neovascularization (For: Daniel Larson)

Acharya, S.

Intramural Research(UNTHSC)

5/06/17 → 31/05/18

Project: Research

Research Output

  • 576 Citations
  • 10 h-Index
  • 17 Article

Hybrid compound sa-2 is neuroprotective in animal models of retinal ganglion cell death

Stankowska, D. L., Dibas, A., Li, L., Zhang, W., Krishnamoorthy, V. R., Chavala, S. H., Nguyen, T. P., Yorio, T., Ellis, D. Z. & Acharya, S., Jul 2019, In : Investigative Ophthalmology and Visual Science. 60, 8, p. 3064-3073 10 p.

Research output: Contribution to journal › Article

Open Access

    • Novel Chitohexaose Analog Protects Young and Aged mice from CLP Induced Polymicrobial Sepsis

    Das, P., Panda, S. K., Agarwal, B., Behera, S., Ali, S. M., Pulse, M. E., Solomkin, J. S., Opal, S. M., Bhandari, V. & Acharya, S., 1 Dec 2019, In : Scientific Reports. 9, 1, 2904.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    Hybrid Nitric Oxide Donor and its Carrier for the Treatment of Peripheral Arterial Diseases

    Le, D. Q., Kuriakose, A. E., Nguyen, D. X., Nguyen, K. T. & Acharya, S., 1 Dec 2017, In : Scientific Reports. 7, 1, 8692.

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy

    Acharya, S., Rogers, P., Krishnamoorthy, R. R., Stankowska, D. L., Dias, H. V. R. & Yorio, T., 1 Mar 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 5, p. 1490-1494 5 p.

    Research output: Contribution to journal › Article

    • 7 Scopus citations

    Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity

    Feng, Z., Acharya, S., Klimko, P. G., Hellberg, M. R., May, J. A., Kelly, C., Williams, G., McLaughlin, M. A. & Sharif, N. A., 1 Jun 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 11, p. 2998-3002 5 p.

    Research output: Contribution to journal › Article

    • 18 Scopus citations