Photo of Stella Goulopoulou

View Scopus Profile

Stella Goulopoulou, PhD

  • 1299 Citations
  • 21 h-Index
20042020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Area of Expertise

Research in my lab focuses on vascular physiology and pharmacology. Our long-term goal is to determine what molecular mechanisms facilitate maternal vascular adaptations in pregnancy and how these adaptations determine long-term maternal vascular health. Currently, we are studying the interaction between extracellular mitochondrial DNA and Toll-like receptor 9 to delineate the role of circulating mitochondrial DNA in the development of maternal vascular dysfunction in preeclampsia.
In a different project, we are studying the cross-talk between maternal adipose tissue and maternal arteries. We are interested in understanding how this cross-talk regulates maternal blood flow. We are also interested in understanding how maternal obesity impairs the relationship between maternal adipose tissue and arteries, leading to maternal vascular dysfunction and impaired blood flow to the uteroplacental unit.
Concepts/techniques: Vascular physiology (ex vivo assessment of vascular reactivity and myogenic tone, vascular cell cultures, blood pressure measurements in conscious rodents); Placental biology (placental tissue explants, trophoblast cell lines); Physiology of pregnancy (rodent models, pharmacological interventions); Other (immunohistochemistry, measurements of oxidative stress, ELISA techniques, Western blot, qPCR, laser capture microdissection).

Education/Academic qualification

BS in Physical Education & Sports Science, Kapodistrian University of Athens

MS in Exercise Science, Syracuse University

PhD in Exercise Physiology & Science, Syracuse University

Fingerprint Dive into the research topics where Stella Goulopoulou is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects

Maternal vascular responses to extracellular mitochondrial DNA during pregnancy

Goulopoulou, S.

1/01/20 → 31/12/20

Project: Research

Circulating Cell-Free Mitochondrial DNA in a Preclinical Model of Preeclampsia with Placental Ischemia

Goulopoulou, S. & Phillips, N.

American Heart Association

1/07/19 → 30/06/22

Project: Research

Trophoblast-induced Maternal Cardiovascular Dysfunction in Pregnancy (For:Spencer Cushen)

Goulopoulou, S.

American Heart Association

1/07/18 → 30/06/20

Project: Research

Trophoblast cell responses to hypoxia (For: Ryan T Nguyen)

Goulopoulou, S.

Intramural Research(UNTHSC)

5/06/17 → 31/05/18

Project: Research

Nanosensing of Oxidized Cell-free mtDNA: Biomarkers of Inflammation and Mitochondrial Dysfunction

Phillips, N., Planz, J. & Goulopoulou, S.

Intramural Research(UNTHSC)

1/06/17 → 31/05/18

Project: Research

Research Output

Cell-free mitochondrial DNA increases in maternal circulation during healthy pregnancy: A prospective, longitudinal study

Cushen, S. C., Sprouse, M. L., Blessing, A., Sun, J., Jarvis, S. S., Okada, Y., Fu, Q., Romero, S. A., Phillips, N. R. & Goulopoulou, S., Feb 2020, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 2, p. R445-R452

Research output: Contribution to journal › Article

    • 1 Scopus citations

    A free-choice high-fat, high-sucrose diet induces hyperphagia, obesity, and cardiovascular dysfunction in female cycling and pregnant rats

    Ahmed, H., Hannan, J. L., Apolzan, J. W., Osikoya, O., Cushen, S. C., Romero, S. A. & Goulopoulou, S., 1 May 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 5, p. R472-R485

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Paying the toll for inflammation: Immunoreceptor-mediated vascular dysfunction in hypertension

    McCarthy, C. G., Goulopoulou, S. & Webb, R. C., 1 Mar 2019, In : Hypertension. 73, 3, p. 514-521 8 p.

    Research output: Contribution to journal › Article

    2 Scopus citations

    Prenatal therapeutics and programming of cardiovascular function

    Brennan, L. J., Goulopoulou, S. & Bourque, S. L., Jan 2019, In : Pharmacological Research. 139, p. 261-272 12 p.

    Research output: Contribution to journal › Review article

    • 1 Scopus citations

    Sex differences in developmental origins of cardiovascular disease

    Loria, A. S., Goulopoulou, S., Bourque, S. L. & Davidge, S. T., 1 Jan 2019, Sex Differences in Cardiovascular Physiology and Pathophysiology. Elsevier, p. 253-289 37 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    • 1 Scopus citations