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Personal profile

Area of Expertise

Research in my lab focuses on vascular physiology and pharmacology. Our long-term goal is to determine what molecular mechanisms facilitate maternal vascular adaptations in pregnancy and how these adaptations determine long-term maternal vascular health. Currently, we are studying the interaction between extracellular mitochondrial DNA and Toll-like receptor 9 to delineate the role of circulating mitochondrial DNA in the development of maternal vascular dysfunction in preeclampsia.
In a different project, we are studying the cross-talk between maternal adipose tissue and maternal arteries. We are interested in understanding how this cross-talk regulates maternal blood flow. We are also interested in understanding how maternal obesity impairs the relationship between maternal adipose tissue and arteries, leading to maternal vascular dysfunction and impaired blood flow to the uteroplacental unit.
Concepts/techniques: Vascular physiology (ex vivo assessment of vascular reactivity and myogenic tone, vascular cell cultures, blood pressure measurements in conscious rodents); Placental biology (placental tissue explants, trophoblast cell lines); Physiology of pregnancy (rodent models, pharmacological interventions); Other (immunohistochemistry, measurements of oxidative stress, ELISA techniques, Western blot, qPCR, laser capture microdissection).

Education/Academic qualification

PhD in Exercise Physiology & Science, Syracuse University

MS in Exercise Science, Syracuse University

BS in Physical Education & Sports Science, Kapodistrian University of Athens

Fingerprint Dive into the research topics where Stella Goulopoulou is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 13 Similar Profiles
Blood Vessels Medicine & Life Sciences
Type 2 Diabetes Mellitus Medicine & Life Sciences
Heart Rate Medicine & Life Sciences
Hypertension Medicine & Life Sciences
Blood Pressure Medicine & Life Sciences
Pregnancy Medicine & Life Sciences
Pre-Eclampsia Medicine & Life Sciences
Exercise Medicine & Life Sciences

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Projects 2014 2022

Research Output 2004 2019

  • 1124 Citations
  • 20 h-Index
  • 41 Article
  • 8 Review article
  • 1 Comment/debate
  • 1 Editorial
1 Citation (Scopus)
Hyperphagia
High Fat Diet
Sucrose
Obesity
Mothers
1 Citation (Scopus)

Paying the toll for inflammation: Immunoreceptor-mediated vascular dysfunction in hypertension

McCarthy, C. G., Goulopoulou, S. & Webb, R. C., 1 Mar 2019, In : Hypertension. 73, 3, p. 514-521 8 p.

Research output: Contribution to journalArticle

Blood Vessels
Hypertension
Inflammation

Prenatal therapeutics and programming of cardiovascular function

Brennan, L. J., Goulopoulou, S. & Bourque, S. L., 1 Jan 2019, In : Pharmacological Research. 139, p. 261-272 12 p.

Research output: Contribution to journalReview article

Embryonic and Fetal Development
Cardiovascular Diseases
Pregnancy
Disease Susceptibility
Health

Uterine perivascular adipose tissue is a novel mediator of uterine artery blood flow and reactivity in rat pregnancy

Osikoya, O., Ahmed, H., Panahi, S., Bourque, S. L. & Goulopoulou, S., 1 Jan 2019, In : Journal of Physiology.

Research output: Contribution to journalArticle

Uterine Artery
Adipose Tissue
Pregnancy
Adipocytes
Adipokines

Calpain a novel mediator of MPO (myeloperoxidase)-induced endothelial dysfunction

Goulopoulou, S., 1 Jan 2018, In : Hypertension. 71, 4, p. 574-576 3 p.

Research output: Contribution to journalArticle

Calpain
Peroxidase