• 1230 Citations
  • 21 h-Index
20042020

Research output per year

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Personal profile

Area of Expertise

Research in my lab focuses on vascular physiology and pharmacology. Our long-term goal is to determine what molecular mechanisms facilitate maternal vascular adaptations in pregnancy and how these adaptations determine long-term maternal vascular health. Currently, we are studying the interaction between extracellular mitochondrial DNA and Toll-like receptor 9 to delineate the role of circulating mitochondrial DNA in the development of maternal vascular dysfunction in preeclampsia.
In a different project, we are studying the cross-talk between maternal adipose tissue and maternal arteries. We are interested in understanding how this cross-talk regulates maternal blood flow. We are also interested in understanding how maternal obesity impairs the relationship between maternal adipose tissue and arteries, leading to maternal vascular dysfunction and impaired blood flow to the uteroplacental unit.
Concepts/techniques: Vascular physiology (ex vivo assessment of vascular reactivity and myogenic tone, vascular cell cultures, blood pressure measurements in conscious rodents); Placental biology (placental tissue explants, trophoblast cell lines); Physiology of pregnancy (rodent models, pharmacological interventions); Other (immunohistochemistry, measurements of oxidative stress, ELISA techniques, Western blot, qPCR, laser capture microdissection).

Education/Academic qualification

BS in Physical Education & Sports Science, Kapodistrian University of Athens

MS in Exercise Science, Syracuse University

PhD in Exercise Physiology & Science, Syracuse University

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Projects

Research Output

Cell-free mitochondrial DNA increases in maternal circulation during healthy pregnancy: A prospective, longitudinal study

Cushen, S. C., Sprouse, M. L., Blessing, A., Sun, J., Jarvis, S. S., Okada, Y., Fu, Q., Romero, S. A., Phillips, N. R. & Goulopoulou, S., Feb 2020, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 2, p. R445-R452

Research output: Contribution to journalArticle

  • 1 Scopus citations
  • 2 Scopus citations

    Paying the toll for inflammation: Immunoreceptor-mediated vascular dysfunction in hypertension

    McCarthy, C. G., Goulopoulou, S. & Webb, R. C., 1 Mar 2019, In : Hypertension. 73, 3, p. 514-521 8 p.

    Research output: Contribution to journalArticle

    2 Scopus citations

    Prenatal therapeutics and programming of cardiovascular function

    Brennan, L. J., Goulopoulou, S. & Bourque, S. L., Jan 2019, In : Pharmacological Research. 139, p. 261-272 12 p.

    Research output: Contribution to journalReview article

  • 1 Scopus citations

    Sex differences in developmental origins of cardiovascular disease

    Loria, A. S., Goulopoulou, S., Bourque, S. L. & Davidge, S. T., 1 Jan 2019, Sex Differences in Cardiovascular Physiology and Pathophysiology. Elsevier, p. 253-289 37 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  • 1 Scopus citations