• 3632 Citations
  • 33 h-Index
1984 …2023
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Research Output 1984 2017

  • 3632 Citations
  • 33 h-Index
  • 63 Article
  • 1 Short survey
2017
1 Citation (Scopus)
Biofilms
Candida albicans
Extracellular Matrix
Leukocytes
Phenotype
2016

Binding sites in the EFG1 promoter for transcription factors in a proposed regulatory network: A functional analysis in the white and opaque phases of Candida albicans

Pujol, C., Srikantha, T., Park, Y. N., Daniels, K. J. & Soll, D. R., 1 Jan 2016, In : G3: Genes, Genomes, Genetics. 6, 6, p. 1725-1737 13 p.

Research output: Contribution to journalArticle

Candida albicans
Transcription Factors
Binding Sites
Renilla Luciferases
Phenotype
2015
10 Citations (Scopus)

Role of Tec1 in the development, architecture, and integrity of sexual biofilms of Candida albicans

Daniels, K. J., Srikantha, T., Pujol, C., Park, Y. N. & Soll, D. R., 1 Jan 2015, In : Eukaryotic Cell. 14, 3, p. 228-240 13 p.

Research output: Contribution to journalArticle

Biofilms
Candida albicans
Silicone Elastomers
Mitogen-Activated Protein Kinases
Hyphae
2013
31 Citations (Scopus)

Candida albicans forms a specialized "sexual" as well as "pathogenic" biofilm

Park, Y. N., Daniels, K. J., Pujol, C., Srikantha, T. & Soll, D. R., 1 Aug 2013, In : Eukaryotic Cell. 12, 8, p. 1120-1131 12 p.

Research output: Contribution to journalArticle

Biofilms
Candida albicans
Fluconazole
Mitogen-Activated Protein Kinases
Cyclic AMP
28 Citations (Scopus)

Identification of genes upregulated by the transcription factor bcr1 that are involved in impermeability, impenetrability, and drug resistance of Candida albicans a/α biofilms

Thyagarajan, S., Daniels, K. J., Pujol, C., Kim, E. & Soll, D. R., 1 Jun 2013, In : Eukaryotic Cell. 12, 6, p. 875-888 14 p.

Research output: Contribution to journalArticle

Biofilms
Candida albicans
Drug Resistance
Transcription Factors
Genes
28 Citations (Scopus)

Impact of environmental conditions on the form and function of Candida albicans biofilms

Daniels, K. J., Park, Y. N., Thyagarajan, S., Pujol, C. & Soll, D. R., 1 Oct 2013, In : Eukaryotic Cell. 12, 10, p. 1389-1402 14 p.

Research output: Contribution to journalArticle

Biofilms
Candida albicans
Spiders
Air
Fluconazole
2012
21 Citations (Scopus)

Nonsex genes in the mating type locus of Candida albicans play roles in a/α biofilm formation, including impermeability and fluconazole resistance

Srikantha, T., Daniels, K. J., Pujol, C., Sahni, N., Yi, S. & Soll, D. R., 1 Jan 2012, In : PLoS Pathogens. 8, 1, e1002476.

Research output: Contribution to journalArticle

Fluconazole
Biofilms
Candida albicans
Genes
Co-Repressor Proteins
8 Citations (Scopus)

The "finger," a Unique multicellular morphology of Candida albicans induced by CO2 and dependent upon the ras1-cyclic AMP pathway

Daniels, K. J., Pujol, C., Srikantha, T. & Soll, D. R., 1 Oct 2012, In : Eukaryotic Cell. 11, 10, p. 1257-1267 11 p.

Research output: Contribution to journalArticle

Candida albicans
Cyclic AMP
Fingers
Yeasts
Agar
2011
65 Citations (Scopus)

Alternative mating type configurations (a/α versus a/a or α/α) of candida albicans result in alternative biofilms regulated by different pathways

Yi, S., Sahni, N., Daniels, K. J., Lu, K. L., Srikantha, T., Huang, G., Garnaas, A. M. & Soll, D. R., 1 Aug 2011, In : PLoS Biology. 9, 8, e1001117.

Research output: Contribution to journalArticle

Candida
Biofilms
Candida albicans
biofilm
Signal transduction
16 Citations (Scopus)

Fig1 facilitates calcium influx and localizes to membranes destined to undergo fusion during mating in Candida albicans

Yang, M., Brand, A., Srikantha, T., Daniels, K. J., Soll, D. R. & Gow, N. A. R., 1 Mar 2011, In : Eukaryotic Cell. 10, 3, p. 435-444 10 p.

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Candida albicans
Pheromones
Calcium
Membranes
19 Citations (Scopus)

Self-induction of a/a or α/α biofilms in Candida albicans is a pheromone-based paracrine system requiring switching

Yi, S., Sahni, N., Daniels, K. J., Lu, K. L., Huang, G., Srikantha, T. & Soll, D. R., 1 Jun 2011, In : Eukaryotic Cell. 10, 6, p. 753-760 8 p.

Research output: Contribution to journalArticle

Pheromones
Biofilms
Candida albicans
Genes
Pheromone Receptors
41 Citations (Scopus)

Target specificity of the Candida albicans Efg1 regulator

Lassak, T., Schneider, E., Bussmann, M., Kurtz, D., Manak, J. R., Thyagarajan, S., Soll, D. R. & Ernst, J. F., 1 Nov 2011, In : Molecular Microbiology. 82, 3, p. 602-618 17 p.

Research output: Contribution to journalArticle

Candida albicans
Yeasts
Growth
Down-Regulation
Genome
16 Citations (Scopus)

Utilization of the mating scaffold protein in the evolution of a new signal transduction pathway for biofilm development

Yi, S., Sahni, N., Daniels, K. J., Lu, K. L., Huang, G., Garnaas, A. M., Pujol, C., Srikantha, T. & Soll, D. R., 1 Jan 2011, In : mBio. 2, 1

Research output: Contribution to journalArticle

Biofilms
Signal Transduction
Pheromones
Mitogen-Activated Protein Kinases
Phenotype
2010
138 Citations (Scopus)

N-acetylglucosamine induces white to opaque switching, a mating prerequisite in Candida albicans

Huang, G., Yi, S., Sahni, N., Daniels, K. J., Thyagarajan, S. & Soll, D. R., 1 Mar 2010, In : PLoS Pathogens. 6, 3, e1000806.

Research output: Contribution to journalArticle

Acetylglucosamine
Candida albicans
Gastrointestinal Tract
Temperature
Monosaccharides
57 Citations (Scopus)

Tec1 mediates the pheromone response of the white phenotype of Candida albicans: Insights into the evolution of new signal transduction pathways

Sahni, N., Yi, S., Daniels, K. J., Huang, G., Srikantha, T. & Soll, D. R., 1 May 2010, In : PLoS Biology. 8, 5

Research output: Contribution to journalArticle

Signal transduction
Candida
Pheromones
Candida albicans
pheromones
2009
28 Citations (Scopus)

A Candida albicans-specific region of the α-pheromone receptor plays a selective role in the white cell pheromone response

Yi, S., Sahni, N., Pujol, C., Daniels, K. J., Thyagarajan, S., Ma, N. & Soll, D. R., 1 Feb 2009, In : Molecular Microbiology. 71, 4, p. 925-947 23 p.

Research output: Contribution to journalArticle

Pheromone Receptors
Pheromones
Candida albicans
Biofilms
Mitogen-Activated Protein Kinases
112 Citations (Scopus)

CO2 Regulates White-to-Opaque Switching in Candida albicans

Huang, G., Thyagarajan, S., Sahni, N., Yi, S. & Soll, D. R., 24 Feb 2009, In : Current Biology. 19, 4, p. 330-334 5 p.

Research output: Contribution to journalArticle

Candida
Candida albicans
carbon dioxide
Switches
Phenotype
592 Citations (Scopus)

Evolution of pathogenicity and sexual reproduction in eight Candida genomes

Butler, G., Rasmussen, M. D., Lin, M. F., Santos, M. A. S., Sakthikumar, S., Munro, C. A., Rheinbay, E., Grabherr, M., Forche, A., Reedy, J. L., Agrafioti, I., Arnaud, M. B., Bates, S., Brown, A. J. P., Brunke, S., Costanzo, M. C., Fitzpatrick, D. A., De Groot, P. W. J., Harris, D., Hoyer, L. L. & 31 others, Hube, B., Klis, F. M., Kodira, C., Lennard, N., Logue, M. E., Martin, R., Neiman, A. M., Nikolaou, E., Quail, M. A., Quinn, J., Santos, M. C., Schmitzberger, F. F., Sherlock, G., Shah, P., Silverstein, K. A. T., Skrzypek, M. S., Soll, D., Staggs, R., Stansfield, I., Stumpf, M. P. H., Sudbery, P. E., Thyagarajan, S., Zeng, Q., Berman, J., Berriman, M., Heitman, J., Gow, N. A. R., Lorenz, M. C., Birren, B. W., Kellis, M. & Cuomo, C. A., 4 Jun 2009, In : Nature. 459, 7247, p. 657-662 6 p.

Research output: Contribution to journalArticle

Candida
Reproduction
Virulence
Genome
Genes
46 Citations (Scopus)

Genes selectively up-regulated by pheromone in white cells are involved in biofilm formation in Candida albicans.

Sahni, N., Yi, S., Daniels, K. J., Thyagarajan, S., Pujol, C. & Soll, D. R., 1 Jan 2009, In : PLoS Pathogens. 5, 10

Research output: Contribution to journalArticle

Pheromones
Biofilms
Candida albicans
Genes
Virulence Factors
6 Citations (Scopus)

Sex: Deviant Mating in Yeast

Soll, D. R., Pujol, C. & Thyagarajan, S., 14 Jul 2009, In : Current Biology. 19, 13

Research output: Contribution to journalShort survey

Yeast
Genes
Yeasts
yeasts
gender
2008
17 Citations (Scopus)

Dark brown is the more virulent of the switch phenotypes of Candida glabrata

Srikantha, T., Daniels, K. J., Wu, W., Lockhart, S. R., Yi, S., Sahni, N., Ma, N. & Soll, D. R., 15 Dec 2008, In : Microbiology. 154, 11, p. 3309-3318 10 p.

Research output: Contribution to journalArticle

Candida glabrata
Phenotype
Spleen
Virulence
Liver
48 Citations (Scopus)
Pheromones
Mitogen-Activated Protein Kinases
Candida albicans
GTP-Binding Proteins
Heterotrimeric GTP-Binding Proteins
2007
54 Citations (Scopus)

Heterozygosity of genes on the sex chromosome regulates Candida albicans virulence

Wu, W., Lockhart, S. R., Pujol, C., Thyagarajan, S. & Soll, D. R., 1 Jun 2007, In : Molecular Microbiology. 64, 6, p. 1587-1604 18 p.

Research output: Contribution to journalArticle

Chromosomes, Human, Pair 5
Sex Chromosomes
Candida albicans
Virulence
Uniparental Disomy
2006
119 Citations (Scopus)

Opaque cells signal white cells to form biofilms in Candida albicans

Daniels, K. J., Thyagarajan, S., Lockhart, S. R., Pujol, C. & Soll, D. R., 17 May 2006, In : EMBO Journal. 25, 10, p. 2240-2252 13 p.

Research output: Contribution to journalArticle

Candida
Pheromones
Biofilms
Candida albicans
Pheromone Receptors
36 Citations (Scopus)

The Shwachman-Bodian-Diamond syndrome gene encodes an RNA-binding protein that localizes to the pseudopod of Dictyostelium amoebae during chemotaxis

Wessels, D., Srikantha, T., Yi, S., Kuhl, S., Aravind, L. & Soll, D. R., 15 Jan 2006, In : Journal of Cell Science. 119, 2, p. 370-379 10 p.

Research output: Contribution to journalArticle

Pseudopodia
Amoeba
Dictyostelium
RNA-Binding Proteins
Chemotaxis
141 Citations (Scopus)

TOS9 regulates white-opaque switching in Candida albicans

Srikantha, T., Borneman, A. R., Daniels, K. J., Pujol, C., Wu, W., Seringhaus, M. R., Gerstein, M., Yi, S., Snyder, M. & Soll, D. R., 1 Oct 2006, In : Eukaryotic Cell. 5, 10, p. 1674-1687MP

Research output: Contribution to journalArticle

Candida albicans
Genes
Switch Genes
Co-Repressor Proteins
Chromatin Immunoprecipitation
2005
22 Citations (Scopus)

Phenotypic switching in Candida glabrata accompanied by changes in expression of genes with deduced functions in copper detoxification and stress

Srikantha, T., Zhao, R., Daniels, K., Radke, J. & Soll, D. R., 1 Aug 2005, In : Eukaryotic Cell. 4, 8, p. 1434-1445 12 p.

Research output: Contribution to journalArticle

Candida glabrata
Copper
Gene Expression
Phenotype
Genes
2004
74 Citations (Scopus)

The closely related species Candida albicans and Candida dubliniensis can mate

Pujol, C., Daniels, K. J., Lockhart, S. R., Srikantha, T., Radke, J. B., Geiger, J. & Soll, D. R., 1 Aug 2004, In : Eukaryotic Cell. 3, 4, p. 1015-1027 13 p.

Research output: Contribution to journalArticle

Candida albicans
Candida
Agar
Suspensions
Nuclear Fusion
2003
46 Citations (Scopus)

Phenotypic Switching and Mating Type Switching of Candida glabrata at Sites of Colonization

Brockert, P. J., Lachke, S. A., Srikantha, T., Pujol, C., Galask, R. & Soll, D. R., 1 Dec 2003, In : Infection and Immunity. 71, 12, p. 7109-7118 10 p.

Research output: Contribution to journalArticle

Candida glabrata
Vaginitis
Phenotype
Agar
Genetic Transcription
25 Citations (Scopus)

The regulation of EFG1 in white-opaque switching in Candida albicans involves overlapping promoters

Lachke, S. A., Thyagarajan, S. & Soll, D. R., 1 Apr 2003, In : Molecular Microbiology. 48, 2, p. 523-536 14 p.

Research output: Contribution to journalArticle

Candida albicans
Trans-Activators
Sequence Deletion
Electrophoretic Mobility Shift Assay
Luciferases
46 Citations (Scopus)

Three mating type-like loci in Candida glabrata

Thyagarajan, S., Lachke, S. A. & Soll, D. R., 1 Apr 2003, In : Eukaryotic Cell. 2, 2, p. 328-340 13 p.

Research output: Contribution to journalArticle

Candida glabrata
Saccharomyces cerevisiae
Genotype
Genes
Intergenic DNA
2001
58 Citations (Scopus)

A histone deacetylation inhibitor and mutant promote colony-type switching of the human pathogen Candida albicans

Klar, A. J. S., Thyagarajan, S. & Soll, D. R., 3 Jul 2001, In : Genetics. 158, 2, p. 919-924 6 p.

Research output: Contribution to journalArticle

trichostatin A
Candida albicans
Histones
Histone Deacetylase Inhibitors
Acetylation
89 Citations (Scopus)

The histone deacetylase genes HDA1 and RPD3 play distinct roles in regulation of high-frequency phenotypic switching in Candida albicans

Srikantha, T., Tsai, L., Daniels, K., Klar, A. J. S. & Soll, D. R., 25 Jul 2001, In : Journal of Bacteriology. 183, 15, p. 4614-4625 12 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Candida albicans
Genes
Sequence Analysis
Gene Expression
2000
86 Citations (Scopus)

EFG1 null mutants of Candida albicans switch but cannot express the complete phenotype of white-phase budding cells

Srikantha, T., Tsai, L. K., Daniels, K. & Soll, D. R., 1 Mar 2000, In : Journal of Bacteriology. 182, 6, p. 1580-1591 12 p.

Research output: Contribution to journalArticle

Candida albicans
Phenotype
Complementary DNA
Null Lymphocytes
Messenger RNA
67 Citations (Scopus)

Phenotypic switching in Candida glabrata involves phase-specific regulation of the metallothionein gene MT-II and the newly discovered hemolysin gene HLP

Lachke, S. A., Srikantha, T., Tsai, L. K., Daniels, K. & Soll, D. R., 1 Feb 2000, In : Infection and Immunity. 68, 2, p. 884-895 12 p.

Research output: Contribution to journalArticle

Candida glabrata
Hemolysin Proteins
Metallothionein
Genes
DNA Fingerprinting
1999
46 Citations (Scopus)
Nucleic Acid Repetitive Sequences
Candida albicans
Genetic Recombination
Genome
Sister Chromatid Exchange
151 Citations (Scopus)

Misexpression of the opaque-phase-specific gene PEP1 (SAP1) in the white phase of Candida albicans confers increased virulence in a mouse model of cutaneous infection

Kvaal, C., Lachke, S. A., Srikantha, T., Daniels, K., Mccoy, J. & Soll, D. R., 1 Dec 1999, In : Infection and Immunity. 67, 12, p. 6652-6662 11 p.

Research output: Contribution to journalArticle

Candida albicans
Virulence
Skin
Infection
Genes
1998
1 Citation (Scopus)

Advances in molecular genetics of Candida albicans and Candida glabrata

Brown, A. J. P., Cormack, B. P., Gow, N. A. R., Kvaal, C., Soll, D. R. & Thyagarajan, S., 1 Dec 1998, In : Journal of Medical and Veterinary Mycology. 3, p. 230-237 8 p.

Research output: Contribution to journalArticle

Candida glabrata
Candida albicans
Molecular Biology
Genetic Techniques
Candida
23 Citations (Scopus)

A MADS box protein consensus binding site is necessary and sufficient for activation of the opaque-phase-specific gene OP4 of Candida albicans

Lockhart, S. R., Nguyen, M., Thyagarajan, S. & Soll, D. R., 1 Dec 1998, In : Journal of Bacteriology. 180, 24, p. 6607-6616 10 p.

Research output: Contribution to journalArticle

Candida albicans
Protein Binding
Binding Sites
Genes
Transcriptional Activation
5 Citations (Scopus)

Reporters for the analysis of gene regulation in fungi pathogenic to man

Soll, D. R. & Thyagarajan, S., 1 Jan 1998, In : Current Opinion in Microbiology. 1, 4, p. 400-405 6 p.

Research output: Contribution to journalArticle

Reporter Genes
Fungi
Hyphae
Codon
Cues
82 Citations (Scopus)

The two-component hybrid kinase regulator CaNIK1 of Candida albicans

Srikantha, T., Tsai, L., Daniels, K., Enger, L., Highley, K. & Soll, D. R., Oct 1998, In : Microbiology. 144, 10, p. 2715-2729 15 p.

Research output: Contribution to journalArticle

Hyphae
Candida albicans
Phosphotransferases
Neurospora crassa
Histidine
1997
12 Citations (Scopus)

A novel repeat sequence (CKRS-1) containing a tandemly repeated sub-element (kre) accounts for differences between Candida krusei strains fingerprinted with the probe CkF1,2

Carlotti, A., Thyagarajan, S., Schröppel, K., Kvaal, C., Villard, J. & Soll, D. R., 1 Mar 1997, In : Current Genetics. 31, 3, p. 255-263 9 p.

Research output: Contribution to journalArticle

DNA Fingerprinting
Candida
Base Composition
Restriction Mapping
Intergenic DNA
96 Citations (Scopus)

Misexpression of the white-phase-specific gene WH11 in the opaque phase of Candida albicans affects switching and virulence

Kvaal, C. A., Thyagarajan, S. & Soll, D. R., 7 Nov 1997, In : Infection and Immunity. 65, 11, p. 4468-4475 8 p.

Research output: Contribution to journalArticle

Candida albicans
Virulence
Genes
Phenotype
Open Reading Frames
22 Citations (Scopus)

The WH11 gene of Candida albicans is regulated in two distinct developmental programs through the same transcription activation sequences

Srikantha, T., Tsai, L. K. & Soll, D. R., Jun 1997, In : Journal of Bacteriology. 179, 12, p. 3837-3844 8 p.

Research output: Contribution to journalArticle

Renilla Luciferases
Hyphae
Candida albicans
Transcriptional Activation
Genes
1996
10 Citations (Scopus)

Cytoplasmic localization of the white phase-specific WH11 gene product of Candida albicans

Schröppel, K., Srikantha, T., Wessels, D., DeCock, M., Lockhart, S. R. & Soll, D. R., Aug 1996, In : Microbiology. 142, 8, p. 2245-2254 10 p.

Research output: Contribution to journalArticle

Candida albicans
Immune Sera
Genes
Cell Shape
Heat-Shock Proteins
126 Citations (Scopus)

The sea pansy Renilla reniformis luciferase serves as a sensitive bioluminescent reporter for differential gene expression in Candida albicans

Thyagarajan, S., Klapach, A., Lorenz, W. W., Tsai, L. K., Laughlin, L. A., Gorman, J. A. & Soll, D. R., 1 Jan 1996, In : Journal of Bacteriology. 178, 1, p. 121-129 9 p.

Research output: Contribution to journalArticle

Renilla Luciferases
Candida albicans
Reporter Genes
Gene Expression
Luciferases
1995
125 Citations (Scopus)

Colonizing populations of Candida albicans are clonal in origin but undergo microevolution through C1 fragment reorganization as demonstrated by DNA fingerprinting and C1 sequencing

Lockhart, S. R., Fritch, J. J., Meier, A. S., Schroppel, K., Thyagarajan, S., Galask, R. & Soll, D. R., 1 Jan 1995, In : Journal of Clinical Microbiology. 33, 6, p. 1501-1509 9 p.

Research output: Contribution to journalArticle

DNA Fingerprinting
Candida albicans
Population
Dermatoglyphics
Southern Blotting
47 Citations (Scopus)

Functional analysis of the promoter of the phase-specific WH11 gene of Candida albicans

Thyagarajan, S., Chandrasekhar, A. & Soll, D. R., 1 Jan 1995, In : Molecular and Cellular Biology. 15, 3, p. 1797-1805 9 p.

Research output: Contribution to journalArticle

Candida albicans
Genes
Firefly Luciferases
Trans-Activators
Transcriptional Activation
33 Citations (Scopus)

The frequency of integrative transformation at phase-specific genes of Candida albicans correlates with their transcriptional state

Thyagarajan, S., Morrow, B., Schröppel, K. & Soll, D. R., 1 May 1995, In : MGG Molecular & General Genetics. 246, 3, p. 342-352 11 p.

Research output: Contribution to journalArticle

Candida albicans
Spheroplasts
Genes
Phase Transition
Plasmids
1994
12 Citations (Scopus)

Developmental and molecular biology of switching in Candida albicans

Soll, D. R., Morrow, B., Srikantha, T., Vargas, K. & Wertz, P., Aug 1994, In : Oral Surgery, Oral Medicine, Oral Pathology. 78, 2, p. 194-201 8 p.

Research output: Contribution to journalArticle

Developmental Biology
Candida albicans
Molecular Biology
Genes
Virulence Factors