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Personal profile

Area of Expertise

The O’Bryant laboratory is dedicated to precision medicine in Alzheimer’s disease and other neurodegenerative diseases, including Down syndrome, Lewy Body disease, Parkinson’s disease, traumatic brain injury, and others. The fully translational lab has a Biomarker Core (Dr. Hall, Director), Clinical Core (Dr. Johnson, Director), Administrative Core (Dr. O’Bryant, Director) and Data Core (Dr. Johnson, Director). The lab also has a Neuroimaging Core (USC, Dr. Toga, Director). Dr. O’Bryant's multiple NIH grants focus on novel strategies for disease detection, screening into trials (therapeutic and prevention), and patient stratification for optimal treatment response. As part of this work, the lab has a strong focus on the impact of ethnicity/diversity on cognitive loss during the aging process and runs the one-of-a-kind Health & Aging Brain among Latino Elders (HABLE) study, which is the most comprehensive study of Mexican-American brain aging to date.

Education/Academic qualification

PhD in Clinical Psychology, University at Albany

MA in Clinical Psychology, University at Albany

BS in Psychology, Louisiana State University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Alzheimer Disease Medicine & Life Sciences
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Arsenic Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2023

Research Output 2003 2019

A proteomic signature for dementia with Lewy bodies

O'Bryant, S., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Lewy Body Disease
Proteomics
Parkinson Disease
Dementia
Sensitivity and Specificity

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

Silzer, T., Barber, R. C., Sun, J., Pathak, G., Johnson, L. A., O'Bryant, S. & Phillips, N. R., 1 Mar 2019, In : PLoS ONE. 14, 3, e0213527.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Mexican Americans
Medical problems
Mitochondrial DNA
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus

Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need

International Society to Advance Alzheimer's Research and Treatment, Alzheimer's Association, 1 Feb 2019, In : Alzheimer's and Dementia. 15, 2, p. 292-312 21 p.

Research output: Contribution to journalShort surveyResearchpeer-review

Dementia
Alzheimer Disease
Research
Population

Vascular Depression and Cognition in Mexican Americans

Johnson, L. A., Large, S. E., Izurieta Munoz, H., Hall, J. & O'Bryant, S., 1 Jan 2019, In : Dementia and Geriatric Cognitive Disorders. p. 68-78 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cognition
Blood Vessels
Depression
Geriatrics
Short-Term Memory
4 Citations (Scopus)

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies

Martins, R. N., Villemagne, V., Sohrabi, H. R., Chatterjee, P., Shah, T. M., Verdile, G., Fraser, P., Taddei, K., Gupta, V. B., Rainey-Smith, S. R., Hone, E., Pedrini, S., Lim, W. L., Martins, I., Frost, S., Gupta, S., O'Bryant, S., Rembach, A., Ames, D., Ellis, K. & 17 othersFuller, S. J., Brown, B., Gardener, S. L., Fernando, B., Bharadwaj, P., Burnham, S., Laws, S. M., Barron, A. M., Goozee, K., Wahjoepramono, E. J., Asih, P. R., Doecke, J. D., Salvado, O., Bush, A. I., Rowe, C. C., Gandy, S. E. & Masters, C. L., 1 Jan 2018, In : Journal of Alzheimer's Disease. 62, 3, p. 965-992 28 p.

Research output: Contribution to journalReview articleResearchpeer-review

Amyloid
Alzheimer Disease
Oxidative Stress
Cohort Studies
Biomarkers