Projects per year
Personal profile
Area of Expertise
The O’Bryant laboratory is dedicated to precision medicine in Alzheimer’s disease and other neurodegenerative diseases, including Down syndrome, Lewy Body disease, Parkinson’s disease, traumatic brain injury, and others. The fully translational lab has a Biomarker Core (Dr. Hall, Director), Clinical Core (Dr. Johnson, Director), Administrative Core (Dr. O’Bryant, Director) and Data Core (Dr. Johnson, Director). The lab also has a Neuroimaging Core (USC, Dr. Toga, Director). Dr. O’Bryant's multiple NIH grants focus on novel strategies for disease detection, screening into trials (therapeutic and prevention), and patient stratification for optimal treatment response. As part of this work, the lab has a strong focus on the impact of ethnicity/diversity on cognitive loss during the aging process and runs the one-of-a-kind Health & Aging Brain among Latino Elders (HABLE) study, which is the most comprehensive study of Mexican-American brain aging to date.
Education/Academic qualification
BS in Psychology, Louisiana State University
MA in Clinical Psychology, University at Albany
PhD in Clinical Psychology, University at Albany
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Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects
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Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)
O'Bryant, S., CHRISTIAN, B., Handen, B., Head, E., Mapstone, M., Handen, B., COHEN, A., CHRISTIAN, B., O'BRYANT, S., Head, E., TUDORASCU, D., Ances, B. & LEE, J. H.
30/09/20 → 31/08/21
Project: Research
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Sleep Quality and Mechanistic Links to Alzheimer Disease and Related Disorders among older Mexican Americans and Non-Hispanic Whites
O'Bryant, S., YAFFE, K. & O'BRYANT, S.
15/09/19 → 30/06/21
Project: Research
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Amyloid Burden among Mexican Americans
RISSMAN, R., TOGA, A., RISSMAN, R., TOGA, A., Johnson, L., O'Bryant, S., O'BRYANT, S., O'Bryant, S., JOHNSON, L. & O'BRYANT, S.
30/09/18 → 30/04/21
Project: Research
Research output
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Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer’s disease
the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Jan 2021, In: PLoS ONE. 16, 1 January, e0243902.Research output: Contribution to journal › Article › peer-review
Open Access -
MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints
for the INSIGHT-preAD study group & the Alzheimer Precision Medicine Initiative (APMI), Jun 2021, In: Translational Psychiatry. 11, 1, 78.Research output: Contribution to journal › Article › peer-review
Open Access -
Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer's Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome
Alzheimer’s Biomarker Consortium –Down Syndrome (ABC-DS), 2021, In: Journal of Alzheimer's disease : JAD. 79, 2, p. 671-681 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Recursive Support Vector Machine Biomarker Selection for Alzheimer's Disease
Zhang, F., Petersen, M., Johnson, L., Hall, J. & O'Bryant, S. E., 2021, In: Journal of Alzheimer's Disease. 79, 4, p. 1691-1700 10 p.Research output: Contribution to journal › Article › peer-review
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Age and sex impact plasma NFL and t-Tau trajectories in individuals with subjective memory complaints: a 3-year follow-up study
for the Alzheimer Precision Medicine Initiative (APMI) & the INSIGHT-preAD study group, Dec 2020, In: Alzheimer's Research and Therapy. 12, 1, 147.Research output: Contribution to journal › Article › peer-review
Open Access