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Sid O'Bryant, PhD

  • 4004 Citations
  • 33 h-Index
20032024
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Personal profile

Area of Expertise

The O’Bryant laboratory is dedicated to precision medicine in Alzheimer’s disease and other neurodegenerative diseases, including Down syndrome, Lewy Body disease, Parkinson’s disease, traumatic brain injury, and others. The fully translational lab has a Biomarker Core (Dr. Hall, Director), Clinical Core (Dr. Johnson, Director), Administrative Core (Dr. O’Bryant, Director) and Data Core (Dr. Johnson, Director). The lab also has a Neuroimaging Core (USC, Dr. Toga, Director). Dr. O’Bryant's multiple NIH grants focus on novel strategies for disease detection, screening into trials (therapeutic and prevention), and patient stratification for optimal treatment response. As part of this work, the lab has a strong focus on the impact of ethnicity/diversity on cognitive loss during the aging process and runs the one-of-a-kind Health & Aging Brain among Latino Elders (HABLE) study, which is the most comprehensive study of Mexican-American brain aging to date.

Education/Academic qualification

PhD in Clinical Psychology, University at Albany

MA in Clinical Psychology, University at Albany

BS in Psychology, Louisiana State University

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  • 12 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Dementia Medicine & Life Sciences
Malingering Medicine & Life Sciences
Cognition Medicine & Life Sciences
Depression Medicine & Life Sciences
Neuropsychology Medicine & Life Sciences
Hispanic Americans Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2024

Blood Biomarkers for Discriminating Amongst Neurodegenerative Diseases

O'Bryant, S., Hall, J. & Nandy, R.

Michael J. Fox Fnd for Parkinson's Res

1/06/19 → 31/05/20

Project: Research

Blood-Brain Barrier Disruption as a Biomarker for Peroperative Neurocognitive Disorders: Cognitive Recovery after Elective Surgery (CREATES) Study

O'Bryant, S. & Hall, J.

1/05/19 → 29/02/24

Project: Research

Detection of Elder Abuse Through Emergency Care Technicians (DETECT)

O'Bryant, S.

University of Texas HSC at Houston

15/09/18 → 31/05/23

Project: Research

Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican Americans - Diversity Supplement

O'Bryant, S.

NIA: National Institute on Aging

15/07/18 → 31/05/20

Project: Research

Neurodegeneration in Aging Down Syndrome (NiAD): A Longitudinal Study of Cognition and Biomarkers of Alzheimer's Disease

O'Bryant, S. & Hall, J.

University of Pittsburgh

1/07/18 → 30/04/20

Project: Research

Research Output 2003 2019

1 Citation (Scopus)

A proteomic signature for dementia with Lewy bodies

O'Bryant, S. E., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

Research output: Contribution to journal › Article

Open Access
Lewy Body Disease
Proteomics
Parkinson Disease
Dementia
Sensitivity and Specificity

Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity

Winston, C. N., Romero, H. K., Ellisman, M., Nauss, S., Julovich, D. A., Conger, T., Hall, J. R., Campana, W., O’Bryant, S. E., Nievergelt, C. M., Baker, D. G., Risbrough, V. B. & Rissman, R. A., 2 Oct 2019, In : Frontiers in Neuroscience. 13, 1005.

Research output: Contribution to journal › Article

Open Access
Brain Concussion
Exosomes
Astrocytes
Proteins
Neurogranin

Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Sep 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

Research output: Contribution to journal › Comment/debate

Open Access
Meta-Analysis
Immunity
Alzheimer Disease
Lipids

Blood-based biomarkers for Down syndrome and Alzheimer's disease: A systematic review

Petersen, M. E. & O'Bryant, S., 1 Jul 2019, In : Developmental Neurobiology. 79, 7, p. 699-710 12 p.

Research output: Contribution to journal › Review article

Down Syndrome
Alzheimer Disease
Biomarkers
Chromosomes, Human, Pair 21
Prodromal Symptoms

Blood Biomarkers for Use in Alzheimer Disease - Moving from "if" to "how?"

O'Bryant, S., 1 Sep 2019, In : JAMA Neurology. 76, 9, p. 1009-1010 2 p.

Research output: Contribution to journal › Editorial

Alzheimer Disease
Biomarkers