Projects per year
Personal profile
Area of Expertise
The O’Bryant laboratory is dedicated to precision medicine in Alzheimer’s disease and other neurodegenerative diseases, including Down syndrome, Lewy Body disease, Parkinson’s disease, traumatic brain injury, and others. The fully translational lab has a Biomarker Core (Dr. Hall, Director), Clinical Core (Dr. Johnson, Director), Administrative Core (Dr. O’Bryant, Director) and Data Core (Dr. Johnson, Director). The lab also has a Neuroimaging Core (USC, Dr. Toga, Director). Dr. O’Bryant's multiple NIH grants focus on novel strategies for disease detection, screening into trials (therapeutic and prevention), and patient stratification for optimal treatment response. As part of this work, the lab has a strong focus on the impact of ethnicity/diversity on cognitive loss during the aging process and runs the one-of-a-kind Health & Aging Brain among Latino Elders (HABLE) study, which is the most comprehensive study of Mexican-American brain aging to date.
Education/Academic qualification
BS in Psychology, Louisiana State University
MA in Clinical Psychology, University at Albany
PhD in Clinical Psychology, University at Albany
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Alzheimer Biomarker Consortium - Down Syndrome (ABC-DS)
O'Bryant, S., CHRISTIAN, B., Handen, B., Head, E., Mapstone, M., Handen, B., COHEN, A., CHRISTIAN, B., O'BRYANT, S., Head, E., TUDORASCU, D., Ances, B. & LEE, J. H.
30/09/20 → 31/08/21
Project: Research
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Amyloid Burden among Mexican Americans
RISSMAN, R., TOGA, A., RISSMAN, R., TOGA, A., Johnson, L., O'Bryant, S., O'BRYANT, S., O'Bryant, S., JOHNSON, L., O'BRYANT, S., JOHNSON, L., RISSMAN, R. & TOGA, A.
30/09/18 → 30/04/22
Project: Research
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Detection of Elder Abuse Through Emergency Care Technicians (DETECT)
University of Texas HSC at Houston
15/09/18 → 31/05/23
Project: Research
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A blood screening tool for detecting mild cognitive impairment and Alzheimer's disease among community-dwelling Mexican Americans and non-Hispanic Whites: A method for increasing representation of diverse populations in clinical research
for the HABLE Study Team, 2021, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access -
A Precision Medicine Approach to Treating Alzheimer's Disease Using Rosiglitazone Therapy: A Biomarker Analysis of the REFLECT Trials
O'Bryant, S. E., Zhang, F., Petersen, M., Johnson, L., Hall, J. & Rissman, R. A., 2021, In: Journal of Alzheimer's Disease. 81, 2, p. 557-568 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer’s disease
the INSIGHT-preAD study group & Alzheimer Precision Medicine Initiative (APMI), Jan 2021, In: PLoS ONE. 16, 1 January, e0243902.Research output: Contribution to journal › Article › peer-review
Open Access -
Evaluation of the National Task Group-Early Detection Screen for Dementia: Sensitivity to ‘mild cognitive impairment’ in adults with Down syndrome
The Alzheimer’s Disease in Down Syndrome (ADDS) Consortium, May 2021, In: Journal of Applied Research in Intellectual Disabilities. 34, 3, p. 905-915 11 p.Research output: Contribution to journal › Article › peer-review
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MiRNA-15b and miRNA-125b are associated with regional Aβ-PET and FDG-PET uptake in cognitively normal individuals with subjective memory complaints
for the INSIGHT-preAD study group & the Alzheimer Precision Medicine Initiative (APMI), Jun 2021, In: Translational Psychiatry. 11, 1, 78.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations