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Personal profile

Area of Expertise

The O’Bryant laboratory is dedicated to precision medicine in Alzheimer’s disease and other neurodegenerative diseases, including Down syndrome, Lewy Body disease, Parkinson’s disease, traumatic brain injury, and others. The fully translational lab has a Biomarker Core (Dr. Hall, Director), Clinical Core (Dr. Johnson, Director), Administrative Core (Dr. O’Bryant, Director) and Data Core (Dr. Johnson, Director). The lab also has a Neuroimaging Core (USC, Dr. Toga, Director). Dr. O’Bryant's multiple NIH grants focus on novel strategies for disease detection, screening into trials (therapeutic and prevention), and patient stratification for optimal treatment response. As part of this work, the lab has a strong focus on the impact of ethnicity/diversity on cognitive loss during the aging process and runs the one-of-a-kind Health & Aging Brain among Latino Elders (HABLE) study, which is the most comprehensive study of Mexican-American brain aging to date.

Education/Academic qualification

PhD in Clinical Psychology, University at Albany

MA in Clinical Psychology, University at Albany

BS in Psychology, Louisiana State University

Fingerprint Dive into the research topics where Sid O'Bryant is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 12 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Malingering Medicine & Life Sciences
Dementia Medicine & Life Sciences
Cognition Medicine & Life Sciences
Depression Medicine & Life Sciences
Neuropsychology Medicine & Life Sciences
Hispanic Americans Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2023

Research Output 2003 2019

1 Citation (Scopus)

A proteomic signature for dementia with Lewy bodies

O'Bryant, S., Ferman, T. J., Zhang, F., Hall, J., Pedraza, O., Wszolek, Z. K., Como, T., Julovich, D., Mattevada, S., Johnson, L. A., Edwards, M. & Graff-Radford, N. R., 1 Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 270-276 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Lewy Body Disease
Proteomics
Parkinson Disease
Dementia
Sensitivity and Specificity

Blood Biomarkers for Use in Alzheimer Disease - Moving from "if" to "how?"

O'Bryant, S., 1 Jan 2019, In : JAMA Neurology.

Research output: Contribution to journalEditorialResearch

Alzheimer Disease
Biomarkers

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

Silzer, T., Barber, R. C., Sun, J., Pathak, G., Johnson, L. A., O'Bryant, S. & Phillips, N. R., 1 Mar 2019, In : PLoS ONE. 14, 3, e0213527.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Mexican Americans
Medical problems
Mitochondrial DNA
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus

Differential default mode network trajectories in asymptomatic individuals at risk for Alzheimer's disease

INSIGHT-preAD Study Group & Alzheimer Precision Medicine Initiative (APMI), 1 Jul 2019, In : Alzheimer's and Dementia. 15, 7, p. 940-950 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Apolipoprotein E4
Amyloid
Alzheimer Disease
Brain
Frontal Lobe

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Mar 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Meta-Analysis
Immunity
Alzheimer Disease
Lipids
Serum Amyloid A Protein