• 295 Citations
  • 9 h-Index
20042020
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Research Output 2004 2018

  • 295 Citations
  • 9 h-Index
  • 16 Article
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Article
2018
4 Citations (Scopus)

Targets of neuroprotection in glaucoma

He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. & Yorio, T., 1 Jan 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Glaucoma
Retinal Diseases
Western World
Retinal Ganglion Cells
Aqueous Humor
2017

A feed-forward regulation of endothelin receptors by c-Jun in human non-pigmented ciliary epithelial cells and retinal ganglion cells

Wang, J., Ma, H. Y., Krishnamoorthy, R., Yorio, T. & He, S., 1 Sep 2017, In : PLoS ONE. 12, 9, e0185390.

Research output: Contribution to journalArticleResearchpeer-review

CCAAT-Enhancer-Binding Proteins
Endothelin Receptors
food law
endothelins
Endothelin B Receptors
4 Citations (Scopus)

Sigma-1 receptor regulates mitochondrial function in glucose-and oxygen-deprived retinal ganglion cells

Ellis, D. Z., Li, L., Park, Y., He, S., Mueller, B. & Yorio, T., 1 May 2017, In : Investigative Ophthalmology and Visual Science. 58, 5, p. 2755-2764 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Retinal Ganglion Cells
Oxygen
Glucose
Mitochondrial Membrane Potential
Electron Transport Complex IV
8 Citations (Scopus)

Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma

McGrady, N. R., Minton, A. Z., Stankowska, D. L., He, S., Jefferies, H. B. & Krishnamoorthy, R., 1 Mar 2017, In : BMC Neuroscience. 18, 1, 27.

Research output: Contribution to journalArticleResearchpeer-review

Endothelin A Receptors
Intraocular Pressure
Glaucoma
Rodentia
Up-Regulation
2016
4 Citations (Scopus)

Involvement of ampa receptor and its flip and flop isoforms in retinal ganglion cell death following oxygen/glucose deprivation

Park, Y. H., Broyles, H. V., He, S., McGrady, N. R., Li, L. & Yorio, T., 1 Feb 2016, In : Investigative Ophthalmology and Visual Science. 57, 2, p. 508-526 19 p.

Research output: Contribution to journalArticleResearchpeer-review

AMPA Receptors
Retinal Ganglion Cells
Protein Isoforms
Cell Death
Oxygen
2015
9 Citations (Scopus)

Endothelin-mediated changes in gene expression in isolated purified rat retinal ganglion cells

He, S., Park, Y. H., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 10, p. 6144-6161 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Retinal Ganglion Cells
Endothelins
Gene Expression
Endothelin-1
Endothelin-2
10 Citations (Scopus)

Neuroprotective effects of transcription factor brn3b in an ocular hypertension rat model of glaucoma

Stankowska, D. L., Minton, A. Z., Rutledge, M. A., Mueller, B. H., Phatak, N. R., He, S., Ma, H. Y., Forster, M. J., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 2, p. 893-907 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Ocular Hypertension
Neuroprotective Agents
Intraocular Pressure
Glaucoma
Transcription Factors
2013
9 Citations (Scopus)

Involvement of AP-1 and C/EBPβ in upregulation of endothelin B (ETB) receptor expression in a rodent model of glaucoma

He, S., Minton, A. Z., Ma, H. Y., Stankowska, D. L., Sun, X. L. & Krishnamoorthy, R., 12 Nov 2013, In : PLoS ONE. 8, 11, e79183.

Research output: Contribution to journalArticleResearchpeer-review

Endothelin B Receptors
glaucoma
endothelins
Transcription Factor AP-1
Glaucoma
29 Citations (Scopus)

Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells

Wang, Y., Ding, M., Chaudhari, S., Ding, Y., Yuan, J. P., Stankowska, D. L., He, S., Krishnamoorthy, R., Cunningham, J. T. & Ma, R., 3 May 2013, In : Journal of Biological Chemistry. 288, 18, p. 12852-12865 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Protein Kinase C
Reactive Oxygen Species
Acetates
Kidney
Phosphorylation
2012
35 Citations (Scopus)

Endothelin b receptors contribute to retinal ganglion cell loss in a rat model of glaucoma

Minton, A. Z., Phatak, N. R., Stankowska, D. L., He, S., Ma, H. Y., Mueller, B. H., Jiang, M., Luedtke, R. T., Yang, S., Brownlee, C. & Krishnamoorthy, R., 20 Aug 2012, In : PLoS ONE. 7, 8, e43199.

Research output: Contribution to journalArticleResearchpeer-review

Endothelin Receptors
glaucoma
endothelins
Retinal Ganglion Cells
Endothelins
2010
34 Citations (Scopus)

Combination therapy of 17β-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke

Liu, R., Liu, Q., He, S., Simpkins, J. W. & Yang, S., 1 Mar 2010, In : Journal of Pharmacology and Experimental Therapeutics. 332, 3, p. 1006-1012 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Tissue Plasminogen Activator
Estradiol
Stroke
Middle Cerebral Artery Infarction
Transient Ischemic Attack
2008
30 Citations (Scopus)

Changes in ocular aquaporin-4 (AQP4) expression following retinal injury

Dibas, A., Yang, M. H., He, S., Bobich, J. & Yorio, T., 1 Jan 2008, In : Molecular Vision. 14, p. 1770-1783 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Aquaporin 4
Ubiquitination
Intraocular Pressure
Wounds and Injuries
Glial Fibrillary Acidic Protein
2007
54 Citations (Scopus)

Endothelin-1-mediated signaling in the expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in astrocytes

He, S., Prasanna, G. & Yorio, T., 1 Aug 2007, In : Investigative Ophthalmology and Visual Science. 48, 8, p. 3737-3745 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Tissue Inhibitor of Metalloproteinases
Matrix Metalloproteinase Inhibitors
Endothelin-1
Matrix Metalloproteinases
Astrocytes
14 Citations (Scopus)

Mechanisms of homomeric α1 glycine receptor endocytosis

Huang, R-Q., He, S., Chen, Z., Dillon, G. H. & Leidenheimer, N. J., 16 Oct 2007, In : Biochemistry. 46, 41, p. 11484-11493 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Glycine Receptors
Endocytosis
Dynamins
Acetates
Dialysis
10 Citations (Scopus)

Parallel signaling pathways in endothelin-1-induced proliferation of U373MG astrocytoma cells

He, S., Dibas, A., Yorio, T. & Prasanna, G., 1 Mar 2007, In : Experimental Biology and Medicine. 232, 3, p. 370-384 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytoma
Endothelin-1
Phosphorylation
Cell proliferation
Mitogen-Activated Protein Kinases
2004
41 Citations (Scopus)

Hypoxia augments TNF-α-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes

Desai, D., He, S., Yorio, T., Krishnamoorthy, R. & Prasanna, G., 4 Jun 2004, In : Biochemical and Biophysical Research Communications. 318, 3, p. 642-648 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Optic Disk
Cell proliferation
Endothelin-1
Astrocytes
Optics