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Personal profile

Area of Expertise

My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.

Education/Academic qualification

PhD in Neuroscience, UNT Health Science Center

MD, Peking University

Fingerprint Dive into the research topics where Shaohua Yang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Estrogens Medicine & Life Sciences
Stroke Medicine & Life Sciences
Neuroprotective Agents Medicine & Life Sciences
Middle Cerebral Artery Infarction Medicine & Life Sciences
Brain Ischemia Medicine & Life Sciences
Astrocytes Medicine & Life Sciences
Transient Ischemic Attack Medicine & Life Sciences
Methylene Blue Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2024

Research Output 1997 2019

A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.

Research output: Contribution to journalArticle

Astrocytes
Phenotype
Serum
Fibroblast Growth Factor 2
Epidermal Growth Factor

Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.

Research output: Contribution to journalArticle

Astrocytes
Oxidative Stress
Neuroprotective Agents
Energy Metabolism
Glutamic Acid
2 Citations (Scopus)

Experimental ischemic stroke induces long-term T cell activation in the brain

Xie, L., Li, W., Hersh, J., Liu, R. & Yang, S. H., 1 Nov 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 11, p. 2268-2276 9 p.

Research output: Contribution to journalArticle

Stroke
T-Lymphocytes
Brain
Perforin
Interleukin-17
1 Citation (Scopus)

Aging health and R & D for healthy longevity must be included into the WHO work program

Stambler, I., Jin, K., Lederman, S., Barzilai, N., Jay Olshansky, S., Omokaro, E., Barratt, J., Anisimov, V. N., Rattan, S., Yang, S., Forster, M. J. & Byles, J., 1 Apr 2018, In : Aging and Disease. 9, 2, p. 331-333 3 p.

Research output: Contribution to journalEditorial

Health
3 Citations (Scopus)

Artemisinin prevents glutamate-induced neuronal cell death via Akt pathway activation

Lin, S. P., Li, W., Winters, A., Liu, R. & Yang, S., 20 Apr 2018, In : Frontiers in Cellular Neuroscience. 12, 108.

Research output: Contribution to journalArticle

Glutamic Acid
Cell Death
artemisinine
Mitochondrial Membrane Potential
Antimalarials