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Shaohua Yang, MD, PhD

  • 5471 Citations
  • 43 h-Index
19972020

Research output per year

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Personal profile

Area of Expertise

My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.

Education/Academic qualification

MD, Peking University

PhD in Neuroscience, UNT Health Science Center

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Projects

Post Stroke Cognitive Impairment: Mechanism and Therapy

Yang, S., Liu, R., Sumien, N. & Jin, K.

NINDS: Neurological Disorders & Stroke

1/02/19 → 31/01/24

Project: Research

Brain Targeted RNAi Therapy for Alzheimer's Disease

Raut, S. & Yang, S.

Alzheimer's Disease Program

22/08/18 → 31/08/20

Project: Research

Susceptibility of Cerebellar Purkinje Cells to Oxidative Stress

Huang, R. & Yang, S.

William & Ella Owens Med Research Foun

1/10/17 → 31/12/18

Project: Research

Metformin and Vascular Cognitive Impairment (For: Kiran Chaudhari)

Yang, S.

American Heart Association

1/07/17 → 30/06/19

Project: Research

Oxidative stress and neuroprotection (For: Irfath Kahn)

Yang, S.

Intramural Research(UNTHSC)

5/06/17 → 31/05/18

Project: Research

Research Output

Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm

Chaudhari, K., Wang, J., Xu, Y., Winters, A., Wang, L., Dong, X., Cheng, E. Y., Liu, R. & Yang, S. H., Jun 2020, In : PLoS ONE. 15, 6, e0234571.

Research output: Contribution to journal › Article

Open Access

    • Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells

    Chaphalkar, R. M., Stankowska, D. L., He, S., Kodati, B., Phillips, N., Prah, J., Yang, S. & Krishnamoorthy, R. R., 1 Dec 2020, In : Scientific Reports. 10, 1, 3571.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Metformin and cognition from the perspectives of sex, age, and disease

    Chaudhari, K., Reynolds, C. D. & Yang, S. H., 1 Feb 2020, In : GeroScience. 42, 1, p. 97-116 20 p.

    Research output: Contribution to journal › Review article

    • 4 Scopus citations

    A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype

    Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress

    Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.

    Research output: Contribution to journal › Article

    • 2 Scopus citations