Projects per year
Personal profile
Area of Expertise
My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.
Education/Academic qualification
MD, Peking University
PhD in Neuroscience, UNT Health Science Center
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Projects
Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
Brain Targeted RNAi Therapy for Alzheimer's Disease
Raut, S. & Yang, S.
22/08/18 → 31/08/20
Project: Research
Susceptibility of Cerebellar Purkinje Cells to Oxidative Stress
William & Ella Owens Med Research Foun
1/10/17 → 31/12/18
Project: Research
Metformin and Vascular Cognitive Impairment (For: Kiran Chaudhari)
1/07/17 → 30/06/19
Project: Research
Research Output
Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
Chaudhari, K., Wang, J., Xu, Y., Winters, A., Wang, L., Dong, X., Cheng, E. Y., Liu, R. & Yang, S. H., 1 Jan 2020, In : PLoS ONE. 15, 6, p. e0234571Research output: Contribution to journal › Article
Open Access
Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells
Chaphalkar, R. M., Stankowska, D. L., He, S., Kodati, B., Phillips, N., Prah, J., Yang, S. & Krishnamoorthy, R. R., 1 Dec 2020, In : Scientific Reports. 10, 1, 3571.Research output: Contribution to journal › Article
Open Access
Metformin and cognition from the perspectives of sex, age, and disease
Chaudhari, K., Reynolds, C. D. & Yang, S. H., 1 Feb 2020, In : GeroScience. 42, 1, p. 97-116 20 p.Research output: Contribution to journal › Review article
2
Scopus
citations
A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype
Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.Research output: Contribution to journal › Article
1
Scopus
citations
Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress
Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.Research output: Contribution to journal › Article
1
Scopus
citations