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Personal profile

Area of Expertise

My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.

Education/Academic qualification

PhD in Neuroscience, UNT Health Science Center

MD, Peking University

Fingerprint Dive into the research topics where Shaohua Yang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Estrogens Medicine & Life Sciences
Stroke Medicine & Life Sciences
Middle Cerebral Artery Infarction Medicine & Life Sciences
Neuroprotective Agents Medicine & Life Sciences
Brain Ischemia Medicine & Life Sciences
Transient Ischemic Attack Medicine & Life Sciences
Methylene Blue Medicine & Life Sciences
Astrocytes Medicine & Life Sciences

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Projects 2010 2024

Research Output 1997 2019

A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype

Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Astrocytes
Phenotype
Serum
Fibroblast Growth Factor 2
Epidermal Growth Factor
1 Citation (Scopus)

Aging health and R & D for healthy longevity must be included into the WHO work program

Stambler, I., Jin, K., Lederman, S., Barzilai, N., Jay Olshansky, S., Omokaro, E., Barratt, J., Anisimov, V. N., Rattan, S., Yang, S., Forster, M. J. & Byles, J., 1 Apr 2018, In : Aging and Disease. 9, 2, p. 331-333 3 p.

Research output: Contribution to journalEditorialResearch

Health
3 Citations (Scopus)

Artemisinin prevents glutamate-induced neuronal cell death via Akt pathway activation

Lin, S. P., Li, W., Winters, A., Liu, R. & Yang, S., 20 Apr 2018, In : Frontiers in Cellular Neuroscience. 12, 108.

Research output: Contribution to journalArticleResearchpeer-review

Glutamic Acid
Cell Death
artemisinine
Mitochondrial Membrane Potential
Antimalarials
2 Citations (Scopus)

Experimental ischemic stroke induces long-term T cell activation in the brain

Xie, L., Li, W., Hersh, J., Liu, R. & Yang, S., 1 Jan 2018, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticleResearchpeer-review

Stroke
T-Lymphocytes
Brain
Perforin
Interleukin-17

Glia–immune interactions post-ischemic stroke and potential therapies

Hersh, J. & Yang, S., 1 Dec 2018, In : Experimental Biology and Medicine. 243, 17-18, p. 1302-1312 11 p.

Research output: Contribution to journalReview articleResearchpeer-review

Immune system
Brain
Neuroglia
Stroke
Immune System