Projects per year
Personal profile
Area of Expertise
My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.
Education/Academic qualification
PhD in Neuroscience, UNT Health Science Center
Award Date: 1 Jan 2002
MD, Peking University
Award Date: 1 Jan 2000
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Projects
Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
Brain Targeted RNAi Therapy for Alzheimer's Disease
Raut, S. & Yang, S.
22/08/18 → 31/08/20
Project: Research
Susceptibility of Cerebellar Purkinje Cells to Oxidative Stress
William & Ella Owens Med Research Foun
1/10/17 → 31/12/18
Project: Research
Metformin and Vascular Cognitive Impairment (For: Kiran Chaudhari)
1/07/17 → 30/06/19
Project: Research
Research Output
Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells
Chaphalkar, R. M., Stankowska, D. L., He, S., Kodati, B., Phillips, N., Prah, J., Yang, S. & Krishnamoorthy, R. R., 1 Dec 2020, In : Scientific Reports. 10, 1, 3571.Research output: Contribution to journal › Article
Open Access
Metformin and cognition from the perspectives of sex, age, and disease
Chaudhari, K., Reynolds, C. D. & Yang, S. H., 1 Jan 2020, (Accepted/In press) In : GeroScience.Research output: Contribution to journal › Review article
A novel serum free primary astrocyte culture method that mimic quiescent astrocyte phenotype
Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 May 2019, In : Journal of Neuroscience Methods. 320, p. 50-63 14 p.Research output: Contribution to journal › Article
1
Scopus
citations
Cholesterol sulfate alters astrocyte metabolism and provides protection against oxidative stress
Prah, J., Winters, A., Chaudhari, K., Hersh, J., Liu, R. & Yang, S. H., 15 Nov 2019, In : Brain Research. 1723, 146378.Research output: Contribution to journal › Article
Experimental ischemic stroke induces long-term T cell activation in the brain
Xie, L., Li, W., Hersh, J., Liu, R. & Yang, S. H., 1 Nov 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 11, p. 2268-2276 9 p.Research output: Contribution to journal › Article
10
Scopus
citations