Projects per year
Personal profile
Area of Expertise
My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.
Education/Academic qualification
MD, Peking University
PhD in Neuroscience, UNT Health Science Center
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Projects
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Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
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Brain Targeted RNAi Therapy for Alzheimer's Disease
Raut, S. & Yang, S.
22/08/18 → 31/08/20
Project: Research
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Susceptibility of Cerebellar Purkinje Cells to Oxidative Stress
Huang, R. & Yang, S.
William & Ella Owens Med Research Foun
1/10/17 → 31/12/18
Project: Research
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Metformin and Vascular Cognitive Impairment (For: Kiran Chaudhari)
1/07/17 → 30/06/19
Project: Research
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Research output
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Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer’s disease
Chaudhari, K., Wang, L., Kruse, J., Winters, A., Sumien, N., Shetty, R., Prah, J., Liu, R., Shi, J., Forster, M. & Yang, S. H., 2021, (Accepted/In press) In: Neurological Research.Research output: Contribution to journal › Article › peer-review
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Modulation of astrocyte phenotype in response to T-cell interaction
Hersh, J., Prah, J., Winters, A., Liu, R. & Yang, S. H., 15 Feb 2021, In: Journal of Neuroimmunology. 351, 577455.Research output: Contribution to journal › Article › peer-review
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Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
Chaudhari, K., Wang, J., Xu, Y., Winters, A., Wang, L., Dong, X., Cheng, E. Y., Liu, R. & Yang, S. H., Jun 2020, In: PLoS ONE. 15, 6, e0234571.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Effects of dietary 5-methoxyindole-2-carboxylic acid on brain functional recovery after ischemic stroke
Sumien, N., Huang, R., Chen, Z., Vann, P. H., Wong, J. M., Li, W., Yang, S., Forster, M. J. & Yan, L. J., 27 Jan 2020, In: Behavioural Brain Research. 378, 112278.Research output: Contribution to journal › Article › peer-review
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Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells
Chaphalkar, R. M., Stankowska, D. L., He, S., Kodati, B., Phillips, N., Prah, J., Yang, S. & Krishnamoorthy, R. R., 1 Dec 2020, In: Scientific Reports. 10, 1, 3571.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations