Projects per year
Personal profile
Area of Expertise
My laboratory is interested in understanding the mechanism of brain disorders and the discovery of novel therapy for ischemic stroke, neurodegenerative diseases, and brain tumor. Our research has been focusing on the brain metabolism and using animal and cell culture models of ischemic stroke, neurodegenerative diseases, and brain tumor to address these issues.
Education/Academic qualification
MD, Peking University
PhD in Neuroscience, UNT Health Science Center
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Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
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Brain Targeted RNAi Therapy for Alzheimer's Disease
Raut, S. & Yang, S.
22/08/18 → 31/08/20
Project: Research
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Susceptibility of Cerebellar Purkinje Cells to Oxidative Stress
Huang, R. & Yang, S.
William & Ella Owens Med Research Foun
1/10/17 → 31/12/18
Project: Research
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Metformin and Vascular Cognitive Impairment (For: Kiran Chaudhari)
1/07/17 → 30/06/19
Project: Research
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Characterizing region-specific glucose metabolic profile of the rodent brain using Seahorse XFe96 analyzer
Wang, L., Chaudhari, K., Winters, A., Sun, Y., Liu, R. & Yang, S. H., 2022, (Accepted/In press) In: Journal of Cerebral Blood Flow and Metabolism.Research output: Contribution to journal › Article › peer-review
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Let-7 underlies metformin-induced inhibition of hepatic glucose production
Xie, D., Chen, F., Zhang, Y., Shi, B., Song, J., Chaudhari, K., Yang, S. H., Zhang, G. J., Sun, X., Taylor, H. S., Li, D. & Huang, Y., 5 Apr 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 14, p. e2122217119Research output: Contribution to journal › Article › peer-review
Open Access -
Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer’s disease
Chaudhari, K., Wang, L., Kruse, J., Winters, A., Sumien, N., Shetty, R., Prah, J., Liu, R., Shi, J., Forster, M. & Yang, S. H., 2021, In: Neurological Research. 43, 7, p. 570-581 12 p.Research output: Contribution to journal › Article › peer-review
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Four Decades of Ischemic Penumbra and Its Implication for Ischemic Stroke
Yang, S. H. & Liu, R., Dec 2021, In: Translational Stroke Research. 12, 6, p. 937-945 9 p.Research output: Contribution to journal › Review article › peer-review
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Modulation of astrocyte phenotype in response to T-cell interaction
Hersh, J., Prah, J., Winters, A., Liu, R. & Yang, S. H., 15 Feb 2021, In: Journal of Neuroimmunology. 351, 577455.Research output: Contribution to journal › Article › peer-review