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Research Output 1987 2017

  • 3156 Citations
  • 22 h-Index
  • 28 Article
  • 1 Review article
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Article
16 Citations (Scopus)

A conserved lysine in the estrogen receptor DNA binding domain regulates ligand activation profiles at AP-1 sites, possibly by controlling interaction with a modulating repressor

Uht, R. M., Webb, P., Nguyen, P., Price, R. H., Valentine, C., Favre, H. & Kushner, P. J., 7 May 2004, In : Nuclear Receptor. 2, 2.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Estrogen Receptors
Lysine
Estrogens
Ligands
69 Citations (Scopus)

A splice variant of estrogen receptor β missing exon 3 displays altered subnuclear localization and capacity for transcriptional activation

Price, R. H., Butler, C. A., Webb, P., Uht, R., Kushner, P. & Handa, R. J., 1 Jan 2001, In : Endocrinology. 142, 5, p. 2039-2049 11 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Transcriptional Activation
Exons
Transcription Factor AP-1
Ligands
2 Citations (Scopus)
Methyl-CpG-Binding Protein 2
Methylation
Corticotropin-Releasing Hormone
Gene expression
Gene Expression
110 Citations (Scopus)
Paraventricular Hypothalamic Nucleus
Vasopressins
Glucocorticoids
Neurons
Peptides
26 Citations (Scopus)

Dexamethasone induces a putative repressor complex and chromatin modifications in the CRH promoter

Sharma, D., Bhave, S., Gregg, E. & Uht, R., 1 Jul 2013, In : Molecular Endocrinology. 27, 7, p. 1142-1152 11 p.

Research output: Contribution to journalArticle

Histone Deacetylase 1
Glucocorticoid Receptors
Dexamethasone
Chromatin
Carrier Proteins
Histone Deacetylases
Tamoxifen
Estradiol
Ligands
Chemical activation
57 Citations (Scopus)
Nucleic Acid Regulatory Sequences
Corticotropin-Releasing Hormone
Estrogen Receptors
Cyclic AMP
Estradiol
78 Citations (Scopus)

Estrogen receptor (ER)β isoforms rather than ERα regulate corticotropin-releasing hormone promoter activity through an alternate pathway

Miller, W. J. S., Suzuki, S., Miller, L. K., Handa, R. & Uht, R. M., 24 Nov 2004, In : Journal of Neuroscience. 24, 47, p. 10628-10635 8 p.

Research output: Contribution to journalArticle

Corticotropin-Releasing Hormone
Estrogen Receptors
Protein Isoforms
Ligands
Glucocorticoids
17 Citations (Scopus)

Estrogen receptor action through target genes with classical and alternative response elements

Kushner, P. J., Webb, P., Uht, R. M., Liu, M. M. & Price, R. H., 1 Nov 2003, In : Pure and Applied Chemistry. 75, 11-12, p. 1757-1769 13 p.

Research output: Contribution to journalArticle

Response Elements
Estrogen Receptors
Estrogens
Genes
Chemical activation
685 Citations (Scopus)

Estrogen receptor pathways to AP-1

Kushner, P. J., Agard, D. A., Greene, G. L., Scanlan, T. S., Shiau, A. K., Uht, R. M. & Webb, P., 30 Nov 2000, In : Journal of Steroid Biochemistry and Molecular Biology. 74, 5, p. 311-317 7 p.

Research output: Contribution to journalArticle

Transcription Factor AP-1
Estrogen Receptors
Transcription
Estrogens
Furylfuramide
23 Citations (Scopus)

Estrogen receptors and the regulation of neural stress responses

Handa, R. J., Mani, S. K. & Uht, R. M., 1 Sep 2012, In : Neuroendocrinology. 96, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Estrogens
Neuropeptides
Knockout Mice
Neurotransmitter Agents
67 Citations (Scopus)

Eukaryotic regulatory elements lurking in plasmid DNA: The activator protein-1 site in puC

Kushner, P. J., Baxter, J. D., Duncan, K. G., Lopez, G. N., Schaufele, F., Uht, R. M., Webb, P. & West, B. L., Apr 1994, In : Molecular Endocrinology. 8, 4, p. 405-407 3 p.

Research output: Contribution to journalArticle

Genetic Transcription
Proto-Oncogene Proteins c-jun
Growth Substances
Proto-Oncogene Proteins c-fos
Bacterial DNA
64 Citations (Scopus)

Glucocorticoids are Required for Food Deprivation‐Induced Increases in Hypothalamic Neuropeptide Y Expression

Ponsalle, P., Srivastava, L. S., Uht, R. M. & White, J. D., Oct 1992, In : Journal of Neuroendocrinology. 4, 5, p. 585-591 7 p.

Research output: Contribution to journalArticle

Neuropeptide Y
Glucocorticoids
Food Deprivation
Food
Messenger RNA
14 Citations (Scopus)

Histone deacetylase 1 (HDAC1) participates in the down-regulation of corticotropin releasing hormone gene (crh) expression

Miller, L., Foradori, C. D., Lalmansingh, A. S., Sharma, D., Handa, R. J. & Uht, R. M., 3 Aug 2011, In : Physiology and Behavior. 104, 2, p. 312-320 9 p.

Research output: Contribution to journalArticle

Histone Deacetylase 1
Corticotropin-Releasing Hormone
Down-Regulation
Gene Expression
trichostatin A
2 Citations (Scopus)

Hypothalamic and amygdalar cell lines differ markedly in mitochondrial rather than nuclear encoded gene expression

Dalwadi, D. A. & Uht, R. M., 21 Jun 2013, In : BMC Genomics. 14, 1, 413.

Research output: Contribution to journalArticle

Gene Expression
Cell Line
Genes
Corticotropin-Releasing Hormone
Amygdala
2 Citations (Scopus)

Mechanisms by which 17β-Estradiol (E2) Suppress Neuronal cox-2 gene expression

Stacey, W., Bhave, S. & Uht, R. M., Sep 2016, In : PLoS ONE. 11, 9, e0161430.

Research output: Contribution to journalArticle

Gene expression
estradiol
Estradiol
trichostatin A
Cyclooxygenase 2
378 Citations (Scopus)

Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): Multiple motifs with different binding specificities

Ding, X. F., Anderson, C. M., Ma, H., Hong, H., Uht, R. M., Kushner, P. J. & Stallcup, M. R., 1 Jan 1998, In : Molecular Endocrinology. 12, 2, p. 302-313 12 p.

Research output: Contribution to journalArticle

Nuclear Receptor Coactivator 2
Nuclear Receptor Coactivator 1
Cytoplasmic and Nuclear Receptors
Binding Sites
Androgen Receptors
61 Citations (Scopus)

Oestrogen receptor function at classical and alternative response elements

Kushner, P. J., Agard, D., Feng, W. J., Lopez, G., Schiau, A., Uht, R. M., Webb, P. & Greene, G., 1 Dec 2000, In : Novartis Foundation Symposium. 230, p. 20-32 13 p.

Research output: Contribution to journalArticle

Response Elements
Estrogen Receptors
Estrogens
Transcription Factor AP-1
Tamoxifen
347 Citations (Scopus)

Opposing action of estrogen receptors α and β on cyclin D1 gene expression

Liu, M. M., Albanese, C., Anderson, C. M., Hilty, K., Webb, P., Uht, R. M., Price, R. H., Pestell, R. G. & Kushn, P. J., 5 Jul 2002, In : Journal of Biological Chemistry. 277, 27, p. 24353-24360 8 p.

Research output: Contribution to journalArticle

bcl-1 Genes
Cyclin D1
Gene expression
Estrogen Receptors
Gene Expression
62 Citations (Scopus)

Radiologic-pathologic findings in raccoon roundworm (Baylisascaris procyonis) encephalitis

Rowley, H. A., Uht, R. M., Kazacos, K. R., Sakanari, J., Wheaton, W. V., Barkovich, A. J. & Bollen, A. W., 29 Feb 2000, In : American Journal of Neuroradiology. 21, 2, p. 415-420 6 p.

Research output: Contribution to journalArticle

Ascaridoidea
Raccoons
Retinitis
Leukoencephalopathies
Parasitic Diseases
31 Citations (Scopus)

Regulation of KLF5 involves the Sp1 transcription factor in human epithelial cells

Chen, C., Zhou, Y., Zhou, Z., Sun, X., Otto, K. B., Uht, R. M. & Dong, J. T., 14 Apr 2004, In : Gene. 330, 1-2, p. 133-142 10 p.

Research output: Contribution to journalArticle

Kruppel-Like Transcription Factors
Transcription Factors
Epithelial Cells
GC Rich Sequence
Cell Line
49 Citations (Scopus)

Regulation of phenylethanolamine N-methyltransferase (PNMT) mRNA in the rat adrenal medulla by corticosterone

Jiang, W., Uht, R. & Bohn, M. C., 1989, In : International Journal of Developmental Neuroscience. 7, 5, p. 513-517,519-520

Research output: Contribution to journalArticle

Phenylethanolamine N-Methyltransferase
Adrenal Medulla
Corticosterone
Messenger RNA
Glucocorticoids
631 Citations (Scopus)

Tamoxifen activation of the estrogen receptor/AP-1 pathway: Potential origin for the cell-specific estrogen-like effects of antiestrogens

Webb, P., Lopez, G. N., Uht, R. M. & Kushner, P. J., 1 Jan 1995, In : Molecular Endocrinology. 9, 4, p. 443-456 14 p.

Research output: Contribution to journalArticle

Estrogen Receptor Modulators
Estrogen Receptor alpha
Transcription Factor AP-1
Tamoxifen
Estrogens
27 Citations (Scopus)

The androgen metabolite, 5α-Androstane-3β,17β-diol (3β-Diol), activates the oxytocin promoter through an estrogen receptor-β pathway

Hiroi, R., Lacagnina, A. F., Hinds, L. R., Carbone, D. G., Uht, R. M. & Handa, R. J., 1 May 2013, In : Endocrinology. 154, 5, p. 1802-1812 11 p.

Research output: Contribution to journalArticle

Androstane-3,17-diol
Oxytocin
Estrogen Receptors
Androgens
Paraventricular Hypothalamic Nucleus
29 Citations (Scopus)

The ERβ ligand 5α-androstane, 3β,17β-diol (3β-diol) regulates hypothalamic oxytocin (Oxt) gene expression

Sharma, D., Handa, R. J. & Uht, R. M., 1 May 2012, In : Endocrinology. 153, 5, p. 2353-2361 9 p.

Research output: Contribution to journalArticle

Androstane-3,17-diol
Oxytocin
Ligands
Gene Expression
Nuclear Receptor Coactivator 1
53 Citations (Scopus)

The protein kinase C-η isoform induces proliferation in glioblastoma cell lines through an ERK/Elk-1 pathway

Uht, R. M., Amos, S., Martin, P. M., Riggan, A. E. & Hussaini, I. M., 3 May 2007, In : Oncogene. 26, 20, p. 2885-2893 9 p.

Research output: Contribution to journalArticle

Mitogen-Activated Protein Kinase 3
Glioblastoma
Protein Kinase C
Protein Isoforms
Cell Line
139 Citations (Scopus)

Transcriptional activities of estrogen and glucocorticoid receptors are functionally integrated at the AP-1 response element

Uht, R. M., Anderson, C. M., Webb, P. & Kushner, P. J., 1 Jan 1997, In : Endocrinology. 138, 7, p. 2900-2908 9 p.

Research output: Contribution to journalArticle

Glucocorticoid Receptors
Transcription Factor AP-1
Response Elements
Estrogen Receptors
Dexamethasone
87 Citations (Scopus)

Ultrastructural localization of glucocorticoid receptor (GR) in hypothalamic paraventricular neurons synthesizing corticotropin releasing factor (CRF)

Liposits, Z., Uht, R. M., Harrison, R. W., Gibbs, F. P., Paull, W. K. & Bohn, M. C., 1 Sep 1987, In : Histochemistry. 87, 5, p. 407-412 6 p.

Research output: Contribution to journalArticle

corticotropin-releasing hormone
Corticotropin-Releasing Hormone
Glucocorticoid Receptors
neurons
Neurons