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Personal profile

Area of Expertise

Population of diabetes mellitus continues to rise in the U.S. Diabetic kidney disease is a major complication of diabetes mellitus and is the most common cause of chronic kidney disease.
The research in our laboratory is directed at understanding the molecular mechanisms of the development of diabetic kidney disease. Specifically, we are interested in the role of different calcium signaling pathways in the diabetes-induced kidney injury. Toward this goal, we use both animal models of diabetes mellitus and cultured kidney cells to study how altering calcium signaling changes the function and structure of the kidney/kidney cells under a diabetic environment. We utilize quantitative immunological methods, immunohistochemistry, and RT-PCR to reliably measure both protein and message for various molecules in specific calcium signaling pathways in kidney tissues/kidney cells. We also employ multiple tools to evaluate kidney function under different conditions. It is our goal to better understand the molecular events involved in the kidney response to diabetes, so that we can target rational development of effective therapeutics to prevent/treat the disease.

Education/Academic qualification

PhD in Physiology, University of Nebraska Medical Center

MS in Physiology, Anhui Medical University

BS in Medicine, Anhui Medical University

Fingerprint Dive into the research topics where Rong Ma is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Projects 2011 2021

Research Output 1990 2019

  • 1649 Citations
  • 27 h-Index
  • 55 Article
  • 7 Review article
  • 1 Chapter
  • 1 Short survey

Comparison of diabetic nephropathy between male and female eNOS-/- db/db mice

Ma, Y., Li, W., Shotorbani, P. Y., Dubansky, B. H., Huang, L., Chaudhari, S., Wu, P., Wang, L. A., Ryou, M. G., Zhou, Z. & Ma, R., 1 May 2019, In : American Journal of Physiology - Renal Physiology. 316, 5, p. F889-F897

Research output: Contribution to journalArticleResearchpeer-review

Diabetic Nephropathies
Sex Characteristics
Kidney
Physiological Phenomena
Albuminuria

Short-term high-glucose treatment decreased abundance of Orai1 protein through posttranslational mechanisms in rat Mesangial cells

Jiang, H., Zou, S., Chaudhari, S. & Ma, R., 1 Jan 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F855-F863

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Glucose
Proteins
Ubiquitination
Period Circadian Proteins
4 Citations (Scopus)

Effects of Shu Gan Jian Pi formula on rats with carbon tetrachloride-induced Liver fibrosis using serum metabonomics based on gas chromatography-time of flight mass spectrometry

Jiang, H., Qin, X. J., Li, W. P., Ma, R., Wang, T. & Li, Z. Q., 1 Oct 2017, In : Molecular Medicine Reports. 16, 4, p. 3901-3909 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolomics
Carbon Tetrachloride
Liver Cirrhosis
Gas chromatography
Gas Chromatography
3 Citations (Scopus)

Increased glomerular filtration rate and impaired contractile function of mesangial cells in TRPC6 knockout mice

Li, W., Ding, Y., Smedley, C., Wang, Y., Chaudhari, S., Birnbaumer, L. & Ma, R., 1 Dec 2017, In : Scientific Reports. 7, 1, 4145.

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Glomerular Filtration Rate
Knockout Mice
Kidney
Small Interfering RNA
4 Citations (Scopus)

Negative regulation of smad1 pathway and collagen IV expression by store-operated Ca2+ entry in glomerular mesangial cells

Wu, P., Ren, Y., Ma, Y., Wang, Y., Jiang, H., Chaudhari, S., Davis, M. E., Zuckerman, J. E. & Ma, R., 4 Jun 2017, In : American Journal of Physiology - Renal Physiology. 312, 6, p. F1090-F1100

Research output: Contribution to journalArticleResearchpeer-review

Mesangial Cells
Collagen
Smad1 Protein
Small Interfering RNA
Proteins