• 2489 Citations
  • 28 h-Index
1984 …2022

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[Role of restricted nitric oxide overproduction in the cardioprotective effect of adaptation to intermittent hypoxia].

goriacheva, A. V., Belkina, L. M., Terekhina, O. L., Dawney, H. F., Mallet, R. T., Smirin, B. V., Smirnova, E. A., Mashina, S. I. & Manukhina, E. B., 1 Jan 2012, In : Patologicheskaia fiziologiia i èksperimental'naia terapiia. 1, p. 23-28 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Acetoacetate augments β-adrenergic inotropism of stunned myocardium by an antioxidant mechanism

Squires, J. E., Sun, J., Caffrey, J. L., Yoshishige, D. & Mallet, R. T., 1 Apr 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 284, 4 53-4

Research output: Contribution to journalArticle

20 Scopus citations

Adenosine receptor blockade enhances glycolysis in hypoperfused guinea-pig myocardium

Gao, Z. P., Downey, H. F., Jie, S., He, M. X. & Mallet, R. T., 1 Jan 1997, In : Cardiovascular Research. 33, 1, p. 31-44 14 p.

Research output: Contribution to journalArticle

15 Scopus citations

Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios.

Kelleher, J. K., Bryan, B. M., Mallet, R. T., Holleran, A. L., Murphy, A. N. & Fiskum, G., 15 Sep 1987, In : The Biochemical journal. 246, 3, p. 633-639 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Antioxidant properties of pyruvate mediate its potentiation of β-adrenergic inotropism in stunned myocardium

Tejero-Taldo, M. I., Caffrey, J. L., Sun, J. & Mallet, R. T., 1 Jan 1999, In : Journal of Molecular and Cellular Cardiology. 31, 10, p. 1863-1872 10 p.

Research output: Contribution to journalArticle

63 Scopus citations

A putative mitochondrial mechanism for antioxidative cytoprotection by 17beta-estradiol

Moor, A. N., Gottipati, S., Mallet, R. T., Sun, J., Giblin, F. J., Roque, R. & Cammarata, P. R., 1 May 2004, In : Experimental eye research. 78, 5, p. 933-944 12 p.

Research output: Contribution to journalArticle

33 Scopus citations

Canine coronary vasodepressor responses to hypoxia are attenuated but not abolished by 8-phenyltheophylline

Lee, S. C., Mallet, R. T., Shizukuda, Y., Williams, A. G. & Downey, H. F., 1 Jan 1992, In : American Journal of Physiology - Heart and Circulatory Physiology. 262, 4 31-4

Research output: Contribution to journalArticle

21 Scopus citations
19 Scopus citations
23 Scopus citations

Dobutamine enhances both contractile function and energy reserves in hypoperfused canine right ventricle

Yi, K. D., Downey, H. F., Bian, X., Fu, M. & Mallet, R. T., 1 Dec 2000, In : American Journal of Physiology - Heart and Circulatory Physiology. 279, 6 48-6

Research output: Contribution to journalArticle

15 Scopus citations

Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?

Gao, Z. P., Downey, H. F., Fan, W. L. & Mallet, R. T., 1 Jan 1995, In : Cardiovascular Research. 29, 6, p. 796-804 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Does interstitial adenosine mediate acute hibernation of Guinea pig myocardium?

Gao, Z. P., Downey, H. F., Fan, W. L. & Mallet, R. T., 1 Sep 1994, In : Cardiovascular Research. 28, 9, p. 796-804 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effect of Na+ on intestinal succinate transport and metabolism in vitro

Moe, A. J., Mallet, R. T., Jackson, M. J., Hollywood, J. A. & Kelleher, J. K., 1 Jan 1988, In : American Journal of Physiology - Cell Physiology. 255, 1, p. 24/1

Research output: Contribution to journalArticle

2 Scopus citations

Effects of Na+ replacement on jejunal epithelial energy metabolism

Mallet, R. T., Jackson, M. J. & Kelleher, J. K., 1 Jan 1985, In : Federation Proceedings. 44, 5, p. No. 7790

Research output: Contribution to journalArticle

Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium

Mallet, R. T., Lee, S. C. & Downey, H. F., 1 Jan 1996, In : Cardiovascular Research. 31, 1, p. 102-116 15 p.

Research output: Contribution to journalArticle

12 Scopus citations

Energetic modulation of cardiac inotropism and sarcoplasmic reticular Ca2+ uptake

Mallet, R. T. & Bünger, R., 20 Oct 1994, In : BBA - Molecular Cell Research. 1224, 1, p. 22-32 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Enhanced cerebral perfusion during brief exposures to cyclic intermittent hypoxemia

Liu, X., Xu, D., Hall, J. R., Ross, S., Chen, S., Liu, H., Mallet, R. T. & Shi, X., 1 Dec 2017, In : Journal of applied physiology (Bethesda, Md. : 1985). 123, 6, p. 1689-1697 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Erythropoietin: Powerful protection of ischemic and post-ischemic brain

Nguyen, A. Q., Cherry, B. H., Scott, G. F., Ryou, M. G. & Mallet, R. T., 12 Nov 2014, In : Experimental Biology and Medicine. 239, 11, p. 1461-1475 15 p.

Research output: Contribution to journalArticle

48 Scopus citations

Exercise training enhances glycolytic and oxidative enzymes in canine ventricular myocardium

Stuewe, S. R., Gwirtz, P. A., Agarwal, N. & Mallet, R. T., 1 Jan 2000, In : Journal of Molecular and Cellular Cardiology. 32, 6, p. 903-913 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Exercise training increases creatin kinase capacity in canine myocardium

Stuewe, S. R., Gwirtz, P. A. & Mallet, R. T., 1 Jan 2001, In : Medicine and Science in Sports and Exercise. 33, 1, p. 92-98 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Featured Article: Pyruvate preserves antiglycation defenses in porcine brain after cardiac arrest

Scott, G. F., Nguyen, A. Q., Cherry, B. H., Hollrah, R. A., Salinas, I., Williams, A. G., Ryou, M. G. & Mallet, R. T., 1 Jan 2017, In : Experimental Biology and Medicine. 242, 10, p. 1095-1103 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Glucose requirement for postischemic recovery of perfused working heart

MALLET, R. T., HARTMAN, D. A. & BÜNGER, R., Mar 1990, In : European Journal of Biochemistry. 188, 2, p. 481-493 13 p.

Research output: Contribution to journalArticle

98 Scopus citations

Hemorrhage simulated by lower body negative pressure provokes an oxidative stress response in healthy young adults

Park, F. S., Kay, V. L., Sprick, J. D., Rosenberg, A. J., Anderson, G. K., Mallet, R. T. & Rickards, C. A., 1 Mar 2019, In : Experimental Biology and Medicine. 244, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

Hyperlipidemia with hypoglycemia reduces myocardial oxygen utilization efficiency but not contractile function during coronary hypoperfusion

Hart, B. J., Bian, X., Mallet, R. T. & Downey, F. H., 1 Jan 2000, In : Journal of Molecular and Cellular Cardiology. 32, 8, p. 1539-1552 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Hypoxic conditioning suppresses nitric oxide production upon myocardial reperfusion

Ryou, M. G., Sun, J., Oguayo, K. N., Manukhina, E. B., Downey, H. F. & Mallet, R. T., 1 Jun 2008, In : Experimental Biology and Medicine. 233, 6, p. 766-774 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Hypoxic preconditioning attenuates stunning caused by repeated coronary artery occlusions in dog heart

Shizukuda, Y., Iwamoto, T., Mallet, R. T. & Downey, H. F., 1 Jan 1993, In : Cardiovascular Research. 27, 4, p. 559-564 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Hypoxic preconditioning of ischaemic canine myocardium

Shizukuda, Y., Mallet, R. T., Lee, S. C. & Downey, H. F., 1 Jan 1992, In : Cardiovascular Research. 26, 5, p. 534-542 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Inline flow sensor for ventriculoperitoneal shunts: Experimental evaluation in swine

Qin, C., Olivencia-Yurvati, A. H., Williams, A. G., Eskildsen, D., Mallet, R. T. & Dasgupta, P. K., May 2019, In : Medical Engineering and Physics. 67, p. 66-72 7 p.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations

Insulin improves cardiac contractile function without further decline in energetics during moderate ischemia

Tune, J. D., Mallet, R. T. & Downey, H. F., 20 Mar 1998, In : FASEB Journal. 12, 5, p. A1000

Research output: Contribution to journalArticle

Insulin improves contractile function during moderate ischemia in canine left ventricle

Tune, J. D., Mallet, R. T. & Downey, H. F., 1 May 1998, In : American Journal of Physiology - Heart and Circulatory Physiology. 274, 5 43-5

Research output: Contribution to journalArticle

45 Scopus citations

Intermittent hypoxia conditioning prevents behavioral deficit and brain oxidative stress in ethanol-withdrawn rats

Jung, M. E., Simpkins, J. W., Wilson, A. M., Downey, H. F. & Mallet, R. T., 1 Aug 2008, In : Journal of Applied Physiology. 105, 2, p. 510-517 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Intermittent hypoxia conditioning protects mitochondrial cytochrome c oxidase of rat cerebellum from ethanol withdrawal stress

Ju, X., Mallet, R. T., Downey, H. F., Metzger, D. B. & Jung, M. E., 15 May 2012, In : Journal of Applied Physiology. 112, 10, p. 1706-1714 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Intermittent hypoxia mobilizes hematopoietic progenitors and augments cellular and humoral elements of innate immunity in adult men

Serebrovskaya, T. V., Nikolsky, I. S., Nikolska, V. V., Mallet, R. T. & Ishchuk, V. A., 1 Oct 2011, In : High Altitude Medicine and Biology. 12, 3, p. 243-252 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
6 Scopus citations

Intermittent Hypoxia Training for Treating Mild Cognitive Impairment: A Pilot Study

Wang, H., Shi, X., Schenck, H., Hall, J. R., Ross, S. E., Kline, G. P., Chen, S., Mallet, R. T. & Chen, P., 1 Jan 2020, In : American journal of Alzheimer's disease and other dementias. 35, p. 1533317519896725

Research output: Contribution to journalArticle

Open Access

Intermittent hypoxia training protects cerebrovascular function in Alzheimer's disease

Manukhina, E. B., Downey, H. F., Shi, X. & Mallet, R. T., 1 Jun 2016, In : Experimental Biology and Medicine. 241, 12, p. 1351-1363 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

Intermittent hypoxic training protects canine myocardium from infarction

Zong, P., Setty, S., Sun, W., Martinez, R., Tune, J. D., Ehrenburg, I. V., Tkatchouk, E. N., Mallet, R. T. & Downey, H. F., Sep 2004, In : Experimental Biology and Medicine. 229, 8, p. 806-812 7 p.

Research output: Contribution to journalArticle

50 Scopus citations

Ischaemic and hypoxic conditioning: potential for protection of vital organs

Sprick, J. D., Mallet, R. T., Przyklenk, K. & Rickards, C. A., 1 Mar 2019, In : Experimental physiology. 104, 3, p. 278-294 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Jejunal epithelial glucose metabolism: Effects of Na+ replacement

Mallet, R. T., Jackson, M. J. & Kelleher, J. K., 1 Dec 1986, In : American Journal of Physiology - Cell Physiology. 251, 5

Research output: Contribution to journalArticle

6 Scopus citations

Leukocyte filtration and aprotinin: Synergistic anti-inflammatory protection

Olivencia-Yurvati, A. H., Wallace, N., Ford, S. & Mallet, R. T., 24 May 2004, In : Perfusion. 19, SUPPL. 1, p. S13-S19

Research output: Contribution to journalArticle

16 Scopus citations

Local glucose utilization and local blood flow in hearts of awake rats

Kuschinsky, W., Bünger, R., Schröck, H., Mallet, R. T. & Sokoloff, L., 1 May 1993, In : Basic research in cardiology. 88, 3, p. 233-249 17 p.

Research output: Contribution to journalArticle

16 Scopus citations

Magnesium activated adenosine formation in intact perfused heart: Predominance of ecto 5′-nucleotidase during hypermagnesemia

Mallet, R. T., Jie, S., Fan, W. L., Kang, Y. H. & Bünger, R., 4 Jun 1996, In : Biochimica et Biophysica Acta - General Subjects. 1290, 2, p. 165-176 12 p.

Research output: Contribution to journalArticle

26 Scopus citations

Metabolic protection of post-ischemic phosphorylation potential and ventricular performance

Mallet, R. T., Bunger, R., Prinzen, F., Allen, D. & Bassingthwaighte, J., 1 Dec 1993, In : Advances in experimental medicine and biology. 346, p. 233-241 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Mitochondrial metabolism of pyruvate is required for its enhancement of cardiac function and energetics

Mallet, R. T. & Sun, J., 1 Apr 1999, In : Cardiovascular Research. 42, 1, p. 149-161 13 p.

Research output: Contribution to journalArticle

59 Scopus citations

Mitochondrial pyruvate transport in working guinea-pig heart. Work-related vs. carrier-mediated control of pyruvate oxidation

Bünger, R. & Mallet, R. T., 19 Sep 1993, In : BBA - Biomembranes. 1151, 2, p. 223-236 14 p.

Research output: Contribution to journalArticle

30 Scopus citations

Myocardial oxygen consumption modulates adenosine formation by canine right ventricle in absence of hypoxia

Bian, X., Fu, M., Mallet, R. T., Bünger, R. & Downey, F. H., 1 Jan 2000, In : Journal of Molecular and Cellular Cardiology. 32, 3, p. 345-354 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Neuronal injury from cardiac arrest: aging years in minutes

Cherry, B. H., Sumien, N. & Mallet, R. T., 1 Jan 2014, In : Age. 36, 4, 9680.

Research output: Contribution to journalArticle

1 Scopus citations

Normobaric, intermittent hypoxia conditioning is cardio- and vasoprotective in rats

Manukhina, E. B., Belkina, L. M., Terekhina, O. L., Abramochkin, D. V., Smirnova, E. A., Budanova, O. P., Mallet, R. T. & Downey, H. F., 1 Dec 2013, In : Experimental Biology and Medicine. 238, 12, p. 1413-1420 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Normobaric hypoxia conditioning reduces blood pressure and normalizes nitric oxide synthesis in patients with arterial hypertension

Lyamina, N. P., Lyamina, S. V., Senchiknin, V. N., Mallet, R. T., Downey, H. F. & Manukhina, E. B., 1 Nov 2011, In : Journal of Hypertension. 29, 11, p. 2265-2272 8 p.

Research output: Contribution to journalArticle

41 Scopus citations