Projects per year
Personal profile
Area of Expertise
My laboratory is interested in developing and characterizing safe and effective drugs that can be used for the treatment of individuals afflicted with Parkinson’s disease, Alzheimer’s disease, schizophrenia, Tourette syndrome, and dystonia. We have also worked to develop drugs that can be used to assist in the rehabilitation of individuals who abuse cocaine. These studies have provided insights on the role of dopamine and sigma receptors in the brain.
Education/Academic qualification
BA in Chemistry, University of Illinois at Urbana-Champaign
BS in Microbiology, University of Illinois at Urbana-Champaign
PhD in Immunology, University of Pennsylvania
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Dive into the research topics where Robert Luedtke is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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UNTHSC Summer Research Internship Program (SRIP)
Jones, H., Luedtke, R. & Vishwanatha, J.
NIDA: National Institute on Drug Abuse
15/04/18 → 28/02/23
Project: Research
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Discovery of Functionally Selective Alzheimer's Disease Therapeutics
NIA: National Institute on Aging
15/09/17 → 31/05/22
Project: Research
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Discovery of functionally selective Alzheimer's disease therapeutics
Schetz, J., Luedtke, R. & Luedtke, R.
15/09/17 → 31/05/22
Project: Research
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Discovery of functionally selective Alzheimer's disease therapeutics
Luedtke, R., Schetz, J. & Luedtke, R.
15/09/17 → 31/05/22
Project: Research
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Sigma 1 Receptor as a Target for Repetitive Concussive Brain Injury
Schreihofer, D., Luedtke, R. & Sumien, N.
1/08/16 → 30/04/18
Project: Research
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Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-arylpentanamides as selective dopamine D3 receptor ligands
Blass, B. E., Chen, P. J., Taylor, M., Griffin, S. A., Gordon, J. C. & Luedtke, R. R., Jan 2022, In: Medicinal Chemistry Research. 31, 1, p. 132-145 14 p.Research output: Contribution to journal › Article › peer-review
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Design, synthesis, and evaluation of functionalized 5-(4-arylpiperazin-1-yl)-N-quinolinyl-pentanamides as selective dopamine D3 receptor ligands
Blass, B. E., Chen, P. J., Taylor, M., Griffin, S. A., Gordon, J. C. & Luedtke, R. R., May 2022, In: Medicinal Chemistry Research. 31, 5, p. 749-761 13 p.Research output: Contribution to journal › Article › peer-review
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Synthesis and evaluation of cyclic diamino benzamide based D3 receptor ligands
Blass, B. E., Chen, P. J., Taylor, M., Griffin, S. A., Gordon, J. C. & Luedtke, R. R., Mar 2022, In: Medicinal Chemistry Research. 31, 3, p. 446-461 16 p.Research output: Contribution to journal › Article › peer-review
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Evaluation of substituted n-phenylpiperazine analogs as D3 vs. D2 dopamine receptor subtype selective ligands
Lee, B., Taylor, M., Griffin, S. A., McInnis, T., Sumien, N., Mach, R. H. & Luedtke, R. R., 1 Jun 2021, In: Molecules. 26, 11, 3182.Research output: Contribution to journal › Article › peer-review
Open Access -
Factors Governing Selectivity of Dopamine Receptor Binding Compounds for D2R and D3R Subtypes
Hayatshahi, H. S., Luedtke, R. R., Taylor, M., Chen, P. J., Blass, B. E. & Liu, J., 28 Jun 2021, In: Journal of Chemical Information and Modeling. 61, 6, p. 2829-2843 15 p.Research output: Contribution to journal › Article › peer-review