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Personal profile

Area of Expertise

Work in my lab is focused on how an individuals’ genetic makeup impacts their risk for Alzheimer’s disease, as well as their age at symptom onset and the rate of disease progression. The goal of our research is to use a combination of genetic variation, demographics, and environmental factors to predict disease risk, age at onset, and progression rate. We are also interested in how disease mechanisms and risk factors differ among ethnic groups, particularly between Mexican Americans and non-Hispanic whites. Research in our group is highly collaborative and active projects are ongoing with labs and scientists across the state and nation.
A second area of research we are interested in is how an individual gut bacteria profile may impact risk for neurodegeneration and the age at onset of cognitive decline.

Education/Academic qualification

PhD in Genetics, Texas A & M University

MS in Marine Biology, Texas A & M University

BS in Biology, Tulane University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2010 2020

Research Output 1993 2019

Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans

Silzer, T., Barber, R. C., Sun, J., Pathak, G., Johnson, L. A., O'Bryant, S. & Phillips, N. R., 1 Mar 2019, In : PLoS ONE. 14, 3, e0213527.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
Mexican Americans
Medical problems
Mitochondrial DNA
noninsulin-dependent diabetes mellitus
Type 2 Diabetes Mellitus

Identification of long non-coding RNA-related and -coexpressed mRNA biomarkers for hepatocellular carcinoma

Zhang, F., Ding, L., Cui, L., Barber, R. C. & Deng, B., 31 Jan 2019, In : BMC Medical Genomics. 12, 25.

Research output: Contribution to journalArticleResearchpeer-review

Long Noncoding RNA
Hepatocellular Carcinoma
Biomarkers
Messenger RNA
Neoplasms

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, 1 Jan 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Cholesterol Ester Transfer Proteins
HDL Cholesterol
Alzheimer Disease
Genes
Single Nucleotide Polymorphism
1 Citation (Scopus)

Odorant Item Specific Olfactory Identification Deficit May Differentiate Alzheimer Disease From Aging

Texas Alzheimer's Research, Care Consortium, 1 Aug 2018, In : American Journal of Geriatric Psychiatry. 26, 8, p. 835-846 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Alzheimer Disease
Smell
Odorants
Healthy Volunteers
Biomarkers

Risk-associated and pathway-based method to detect association with Alzheimer's disease

Mitchel, J., Prokai, L., Deng, Y., Zhang, F. & Barber, R. C., 1 Jan 2018, In : International Journal of Computational Biology and Drug Design. 11, 1-2

Research output: Contribution to journalEditorialResearch

Alzheimer Disease
Alleles
Genome-Wide Association Study
Databases
Genes