Projects per year
Personal profile
Area of Expertise
Work in my lab is focused on how an individuals’ genetic makeup impacts their risk for Alzheimer’s disease, as well as their age at symptom onset and the rate of disease progression. The goal of our research is to use a combination of genetic variation, demographics, and environmental factors to predict disease risk, age at onset, and progression rate. We are also interested in how disease mechanisms and risk factors differ among ethnic groups, particularly between Mexican Americans and non-Hispanic whites. Research in our group is highly collaborative and active projects are ongoing with labs and scientists across the state and nation.
A second area of research we are interested in is how an individual gut bacteria profile may impact risk for neurodegeneration and the age at onset of cognitive decline.
A second area of research we are interested in is how an individual gut bacteria profile may impact risk for neurodegeneration and the age at onset of cognitive decline.
Education/Academic qualification
PhD in Genetics, Texas A & M University
Award Date: 1 Jan 2002
MS in Marine Biology, Texas A & M University
Award Date: 1 Jan 2001
BS in Biology, Tulane University
Award Date: 1 Jan 2000
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Projects
Epigenetic Risk Factors for Early Age at Onset of Alzheimer¿s & MCI Among Non-Caribbean Hispanics
Barber, R., Phillips, N. & Zhou, Z.
22/08/18 → 31/08/20
Project: Research
Texas Center of Minority Health, Education, Research and Outreach - Admin Suppliment
Vishwanatha, J., Phillips, N., Barber, R. & Zhou, Z.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
Research Output
Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer
for the Alzheimer's Disease Neuroimaging Initiative, Breast and Prostate Cancer Cohort Consortium, and Alzheimer's Disease Genetics Consortium, 1 Jan 2020, In : Alzheimer's and Dementia. 16, 1, p. 162-177 16 p.Research output: Contribution to journal › Article
Open Access
Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)
Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Sep 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.Research output: Contribution to journal › Comment/debate
Open Access
Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans
Silzer, T., Barber, R., Sun, J., Pathak, G., Johnson, L., O’Bryant, S. & Phillips, N., Mar 2019, In : PLoS ONE. 14, 3, e0213527.Research output: Contribution to journal › Article
Open Access
3
Scopus
citations
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Mar 2019, In : Nature Genetics. 51, 3, p. 414-430 17 p.Research output: Contribution to journal › Article
103
Scopus
citations
Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities
Pathak, G. A., Silzer, T. K., Sun, J., Zhou, Z., Daniel, A. A., Johnson, L., O'Bryant, S., Phillips, N. R. & Barber, R. C., 1 Jan 2019, In : Journal of Alzheimer's Disease. 72, 3, p. 733-749 17 p.Research output: Contribution to journal › Article