• 4703 Citations
  • 36 h-Index
1993 …2020

Research output per year

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Personal profile

Area of Expertise

Work in my lab is focused on how an individuals’ genetic makeup impacts their risk for Alzheimer’s disease, as well as their age at symptom onset and the rate of disease progression. The goal of our research is to use a combination of genetic variation, demographics, and environmental factors to predict disease risk, age at onset, and progression rate. We are also interested in how disease mechanisms and risk factors differ among ethnic groups, particularly between Mexican Americans and non-Hispanic whites. Research in our group is highly collaborative and active projects are ongoing with labs and scientists across the state and nation.
A second area of research we are interested in is how an individual gut bacteria profile may impact risk for neurodegeneration and the age at onset of cognitive decline.

Education/Academic qualification

MS in Marine Biology, Texas A & M University

PhD in Genetics, Texas A & M University

BS in Biology, Tulane University

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Projects

Research Output

Differentiation of Hispanic biogeographic ancestry with 80 ancestry informative markers

Setser, C. H., Planz, J. V., Barber, R. C., Phillips, N. R., Chakraborty, R. & Cross, D. S., 1 Dec 2020, In : Scientific Reports. 10, 1, 7745.

Research output: Contribution to journalArticle

Open Access
  • Exceptionally low likelihood of Alzheimer’s dementia in APOE2 homozygotes from a 5,000-person neuropathological study

    The Alzheimer’s Disease Genetics Consortium, 1 Dec 2020, In : Nature Communications. 11, 1, 667.

    Research output: Contribution to journalArticle

    Open Access
  • 2 Scopus citations

    Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer

    for the Alzheimer's Disease Neuroimaging Initiative, Breast and Prostate Cancer Cohort Consortium, and Alzheimer's Disease Genetics Consortium, 1 Jan 2020, In : Alzheimer's and Dementia. 16, 1, p. 162-177 16 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations

    Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing (Nature Genetics, (2019), 51, 3, (414-430), 10.1038/s41588-019-0358-2)

    Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), 1 Sep 2019, In : Nature Genetics. 51, 9, p. 1423-1424 2 p.

    Research output: Contribution to journalComment/debate

    Open Access
  • Blood-based protein predictors of dementia severity as measured by δ: Replication across biofluids and cohorts

    Royall, D. R., Bishnoi, R. J., Palmer, R. F., Pavlik, V., Massman, P., Darby, E., Rodriguear, M., Ansari, A. K., DeToledo, J. C., Reddy, H., Wilms, H., Johnson, K., Perez, V., Fairchild, T., Knebl, J., O'Bryant, S. E., Hall, J. R., Johnson, L., Barber, R. C., Mains, D. & 22 others, Alvarez, L., Cullum, M., Rosenberg, R., Williams, B., Quiceno, M. E., Reisch, J., Hynan, L. S., Huebinger, R., Smith, J., Nguyen, T., Royall, D., Palmer, R., Polk, M., Stevens, A., Ory, M., Paydarfar, D., Bertelson, J., Woon, M., Ayres, G., Aguirre, A., Wilhelmsen, K. C. & Tilson, J. L., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 763-774 12 p.

    Research output: Contribution to journalArticle

    Open Access