Rebecca Cunningham public CV

Rebecca Cunningham, PhD

UNT System College of Pharmacy
Associate Professor, Pharmaceutical Sciences
Member, Institute for Healthy Aging

EmailRebecca.Cunningham@unthsc.edu

510 Citations
15 h-Index

Research output per year

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Personal profile

Area of Expertise

Dr. Rebecca Cunningham studies the role of steroid hormones, specifically androgens, from prenatal development to aging. Most of her team’s research has been focused on androgen signaling mechanisms and defining the effects of androgens on central nervous system function. One of Dr. Cunningham’s long-term research goals is to determine how development and aging alters neuronal steroid hormonal responses in an oxidative stress environment, a key characteristic of aging, developmental disorders, and neurodegeneration. She has shown that androgens can either be neuroprotective or damaging, and these effects are dependent on the oxidative stress environment. In pursuing this goal, Dr. Cunningham and team use in vitro, in vivo, and clinical approaches to understand how androgens affect brain function. Hopefully this research will expand the understanding of how steroid hormones impact the brain. At the same time, she seeks to gain new insights that can lead to a better understanding of the role of sex in central nervous system disorders.

Education/Academic qualification

BS in Psychology, Truman State University

PhD in Neurobiology, University of Texas at San Antonio

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Projects

2 Active
15 Finished

Neural Regulation of Vasopresson Release in a model of Dilutaional Hyponatremia

Cunningham, T. & Cunningham, R.

NHLBI: Nat Heart, Lung & Blood Institute

15/04/18 → 31/03/22

Project: Research

Interactions between Testosterone and Oxidative Stress in Dopamine Neurons

Cunningham, R. & Sumien, N.

NINDS: Neurological Disorders & Stroke

1/07/15 → 30/06/20

Project: Research

Cytokine Secretion in dopamine neurons (For: Jenny Trieu)

Cunningham, R.

Intramural Research(UNTHSC)

5/06/17 → 31/05/18

Project: Research

Brain Region Specific Neurodegeneration in Chronic Intermittent Hypoxia (For: Lincoln Downs)

Cunningham, R.

Intramural Research(UNTHSC)

15/10/15 → 15/02/16

Project: Research

Pilot study on the risks of testosterone replacement to the brain

Cunningham, R. & Schreihofer, D.

15/08/15 → 31/05/16

Project: Research

Research Output

510 Citations
15 h-Index
29 Article

Neuroprotective and neurotoxic outcomes of androgens and estrogens in an oxidative stress environment

Duong, P., Tenkorang, M. A. A., Trieu, J., McCuiston, C., Rybalchenko, N. & Cunningham, R. L., 29 Mar 2020, In : Biology of Sex Differences. 11, 1, 12.