Projects per year
Personal profile
Area of Expertise
Dr. Rebecca Cunningham studies the role of steroid hormones, specifically androgens, from prenatal development to aging. Most of her team’s research has been focused on androgen signaling mechanisms and defining the effects of androgens on central nervous system function. One of Dr. Cunningham’s long-term research goals is to determine how development and aging alters neuronal steroid hormonal responses in an oxidative stress environment, a key characteristic of aging, developmental disorders, and neurodegeneration. She has shown that androgens can either be neuroprotective or damaging, and these effects are dependent on the oxidative stress environment. In pursuing this goal, Dr. Cunningham and team use in vitro, in vivo, and clinical approaches to understand how androgens affect brain function. Hopefully this research will expand the understanding of how steroid hormones impact the brain. At the same time, she seeks to gain new insights that can lead to a better understanding of the role of sex in central nervous system disorders.
Education/Academic qualification
BS in Psychology, Truman State University
PhD in Neurobiology, University of Texas at San Antonio
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Projects
- 20 Finished
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Neural Regulation of Vasopresson Release in a model of Dilutaional Hyponatremia
Cunningham, T. & Cunningham, R.
NHLBI: Nat Heart, Lung & Blood Institute
15/04/18 → 31/03/22
Project: Research
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Brain Region Specific Neurodegeneration in Chronic Intermittent Hypoxia (For: Lincoln Downs)
15/10/15 → 15/02/16
Project: Research
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Pilot study on the risks of testosterone replacement to the brain
Cunningham, R. & Schreihofer, D.
15/08/15 → 31/05/18
Project: Research
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Pilot study on the risks of testosterone replacement to the brain
Cunningham, R., Schreihofer, D., Cunningham, R. & Schreihofer, D.
15/08/15 → 31/05/16
Project: Research
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Anterior pituitary, sex hormones, and keratoconus: Beyond traditional targets
Karamichos, D., Escandon, P., Vasini, B., Nicholas, S. E., Van, L., Dang, D. H., Cunningham, R. L. & Riaz, K. M., May 2022, In: Progress in Retinal and Eye Research. 88, 101016.Research output: Contribution to journal › Short survey › peer-review
3 Scopus citations -
The Role of Estriol and Estrone in Keratoconic Stromal Sex Hormone Receptors
Escandon, P., Nicholas, S. E., Cunningham, R. L., Murphy, D. A., Riaz, K. M. & Karamichos, D., 1 Jan 2022, In: International journal of molecular sciences. 23, 2, 916.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Role of Lipid Rafts and Membrane Androgen Receptors in Androgen's Neurotoxic Effects
Fadeyibi, O., Rybalchenko, N., Mabry, S., Nguyen, D. H. & Cunningham, R. L., 1 May 2022, In: Journal of the Endocrine Society. 6, 5, bvac030.Research output: Contribution to journal › Article › peer-review
Open Access -
Is there a Neurobiological Rationale for the Utility of the Iowa Gambling Task in Parkinson's Disease?
Salvatore, M. F., Soto, I., Alphonso, H., Cunningham, R., James, R. & Nejtek, V. A., 2021, In: Journal of Parkinson's Disease. 11, 2, p. 405-419 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access2 Scopus citations -
Neurodegenerative Disease: Roles for Sex, Hormones, and Oxidative Stress
Sumien, N., Cunningham, J. T., Davis, D. L., Engelland, R., Fadeyibi, O., Farmer, G. E., Mabry, S., Mensah-Kane, P., Trinh, O. T. P., Vann, P. H., Wilson, E. N. & Cunningham, R. L., 1 Nov 2021, In: Endocrinology (United States). 162, 11, bqab185.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations