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Personal profile

Area of Expertise

Dr. Rebecca Cunningham studies the role of steroid hormones, specifically androgens, from prenatal development to aging. Most of her team’s research has been focused on androgen signaling mechanisms and defining the effects of androgens on central nervous system function. One of Dr. Cunningham’s long-term research goals is to determine how development and aging alters neuronal steroid hormonal responses in an oxidative stress environment, a key characteristic of aging, developmental disorders, and neurodegeneration. She has shown that androgens can either be neuroprotective or damaging, and these effects are dependent on the oxidative stress environment. In pursuing this goal, Dr. Cunningham and team use in vitro, in vivo, and clinical approaches to understand how androgens affect brain function. Hopefully this research will expand the understanding of how steroid hormones impact the brain. At the same time, she seeks to gain new insights that can lead to a better understanding of the role of sex in central nervous system disorders.

Education/Academic qualification

PhD in Neurobiology, University of Texas at San Antonio

BS in Psychology, Truman State University

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Projects 2010 2022

Research Output 2006 2019

  • 396 Citations
  • 13 h-Index
  • 27 Article

NADPH Oxidase Mediates Membrane Androgen Receptor-Induced Neurodegeneration

Tenkorang, M. A. A., Duong, P. & Cunningham, R. L., 1 Apr 2019, In : Endocrinology. 160, 4, p. 947-963 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Androgen Receptors
NAD
Oxidoreductases
Oxidative Stress
Phosphates
1 Citation (Scopus)

Androgens modulate chronic intermittent hypoxia effects on brain and behavior

Snyder, B., Duong, P., Trieu, J. & Cunningham, R. L., 1 Nov 2018, In : Hormones and Behavior. 106, p. 62-73 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Androgens
Brain
Dihydrotestosterone
Sleep Apnea Syndromes
Oxidative Stress
3 Citations (Scopus)

Chronic intermittent hypoxia induces hormonal and male sexual behavioral changes: Hypoxia as an advancer of aging

Wilson, E. N., Anderson, M., Snyder, B., Duong, P., Trieu, J., Schreihofer, D. & Cunningham, R. L., 15 May 2018, In : Physiology and Behavior. 189, p. 64-73 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Sleep Apnea Syndromes
Oxidative Stress
Testosterone
Sexual Behavior
Hypoxia

N-terminal truncations in sex steroid receptors and rapid steroid actions

Schreihofer, D., Duong, P. & Cunningham, R. L., 1 May 2018, In : Steroids. 133, p. 15-20 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Steroid Receptors
Steroids
Cell Membrane
Cell membranes
Caveolins

Rat strain and housing conditions alter oxidative stress and hormone responses to chronic intermittent hypoxia

Snyder, B., Duong, P., Tenkorang, M., Wilson, E. N. & Cunningham, R. L., 6 Nov 2018, In : Frontiers in Physiology. 9, NOV, 1554.

Research output: Contribution to journalArticleResearchpeer-review

Oxidative Stress
Hormones
Sleep Apnea Syndromes
Long Evans Rats
Pituitary-Adrenal System