Projects per year
Personal profile
Area of Expertise
My laboratory has a long-standing interest in understanding the cellular and molecular aspects of immune responses against pathogenic microorganisms. Specifically, the gram-positive bacterium, Listeria monocytogenes, is utilized to dissect the roles of T cells, NK cells, NK-T cells, dendritic cells, monocytes, neutrophils, and macrophages during the innate and adaptive immune responses to this pathogen. Elucidating the proliferative capacity, cytokine/chemokine secreting potential, localization, and ultimate fate of these and other immune effector cells allows us to understand how the immune system coordinately responds to, and controls, pathogens.
We are also actively studying how cytokine/chemokine networks, oxidative stress, and enzymes that regulate the production of reactive oxygen and nitrogen species modulate immune responses and clearance of pathogens.
We are also actively studying how cytokine/chemokine networks, oxidative stress, and enzymes that regulate the production of reactive oxygen and nitrogen species modulate immune responses and clearance of pathogens.
Education/Academic qualification
BS in Biology, DePaul University
PhD in Microbiology & Immunology, University of Colorado Health Sciences Center
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Projects
Mechanisms of host protection during infection via the mitochondrial unfolded protein response
University of Texas at Arlington
1/10/18 → 31/07/21
Project: Research
Effects of ecSOD on Neutrophil Maturation and Function
American Association of Immunologists
1/09/15 → 31/08/16
Project: Research
Inhibition of NeutroPhil Responses by ecSOD
NIAID: Allergy and Infectious Diseases
1/01/14 → 31/12/17
Project: Research
Research Output
Extracellular superoxide dismutase enhances recruitment of immature neutrophils to the liver
Break, T. J., Witter, A. R., Indramohan, M., Mummert, M. E., Dory, L. & Berg, R. E., 2016, In : Infection and Immunity. 84, 12, p. 3302-3312 11 p.Research output: Contribution to journal › Article
4
Scopus
citations
The essential role of neutrophils during infection with the intracellular bacterial pathogen listeria monocytogenes
Witter, A. R., Okunnu, B. M. & Berg, R. E., 1 Sep 2016, In : Journal of Immunology. 197, 5, p. 1557-1565 9 p.Research output: Contribution to journal › Review article
34
Scopus
citations
Chronic psychological stress suppresses contact hypersensitivity: Potential roles of dysregulated cell trafficking and decreased IFN-γ production
Hall, J. M. F., Witter, A. R., Racine, R. R., Berg, R., Podawiltz, A., Jones, H. & Mummert, M. E., 1 Feb 2014, In : Brain, Behavior, and Immunity. 36, p. 156-164 9 p.Research output: Contribution to journal › Article
8
Scopus
citations
Interleukin-23 (IL-23) deficiency disrupts Th17 and Th1-related defenses against Streptococcus pneumoniae infection
Kim, B. J., Lee, S., Berg, R. E., Simecka, J. W. & Jones, H. P., Oct 2013, In : Cytokine. 64, 1, p. 375-381 7 p.Research output: Contribution to journal › Article
16
Scopus
citations
Extracellular superoxide dismutase inhibits innate immune responses and clearance of an intracellular bacterial infection
Break, T. J., Jun, S., Indramohan, M., Carr, K. D., Sieve, A. N., Dory, L. & Berg, R. E., 1 Apr 2012, In : Journal of Immunology. 188, 7, p. 3342-3350 9 p.Research output: Contribution to journal › Article
34
Scopus
citations