Research output per year
Research output per year
- 1 - 25 out of 44 results
Search results
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Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma
Prasanna, G., Hulet, C., Desai, D., Krishnamoorthy, R. R., Narayan, S., Brun, A. M., Suburo, A. M. & Yorio, T., Jan 2005, In: Pharmacological Research. 51, 1, p. 41-50 10 p.Research output: Contribution to journal › Article › peer-review
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Design and synthesis of novel hybrid sydnonimine and prodrug useful for glaucomatous optic neuropathy
Acharya, S., Rogers, P., Krishnamoorthy, R. R., Stankowska, D. L., Dias, H. V. R. & Yorio, T., 1 Mar 2016, In: Bioorganic and Medicinal Chemistry Letters. 26, 5, p. 1490-1494 5 p.Research output: Contribution to journal › Article › peer-review
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Bcl-2 overexpression protects photooxidative stress-induced apoptosis of photoreceptor cells via NF-κB preservation
Crawford, M. J., Krishnamoorthy, R. R., Rudick, V. L., Collier, R. J., Kapin, M., Aggarwal, B. B., Al-Ubaidi, M. R. & Agarwal, N., 2001, In: Biochemical and Biophysical Research Communications. 281, 5, p. 1304-1312 9 p.Research output: Contribution to journal › Article › peer-review
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Mechanisms contributing to inhibition of retinal ganglion cell death by cell permeable peptain-1 under glaucomatous stress
Johnson, G. A., Kodati, B., Nahomi, R. B., Pham, J. H., Krishnamoorthy, V. R., Phillips, N. R., Krishnamoorthy, R. R., Nagaraj, R. H. & Stankowska, D. L., Dec 2024, In: Cell Death Discovery. 10, 1, 305.Research output: Contribution to journal › Article › peer-review
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Transcription Factor Brn-3b Overexpression Enhances Neurite Outgrowth in PC12 Cells Under Condition of Hypoxia
Phatak, N. R., Stankowska, D. L. & Krishnamoorthy, R. R., 24 Aug 2015, In: Cellular and Molecular Neurobiology. 35, 6, p. 769-783 15 p.Research output: Contribution to journal › Article › peer-review
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Human optic nerve head astrocytes as a target for endothelin-1
Prasanna, G., Krishnamoorthy, R., Clark, A. F., Wordinger, R. J. & Yorio, T., 2002, In: Investigative Ophthalmology and Visual Science. 43, 8, p. 2704-2713 10 p.Research output: Contribution to journal › Article › peer-review
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Characterization of a transformed rat retinal ganglion cell line
Krishnamoorthy, R. R., Agarwal, P., Prasanna, G., Vopat, K., Lambert, W., Sheedlo, H. J., Pang, I. H., Shade, D., Wordinger, R. J., Yorio, T., Clark, A. F. & Agarwal, N., 31 Jan 2001, In: Molecular Brain Research. 86, 1-2, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
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Involvement of AP-1 and C/EBPβ in upregulation of endothelin B (ETB) receptor expression in a rodent model of glaucoma
He, S., Minton, A. Z., Ma, H. Y., Stankowska, D. L., Sun, X. & Krishnamoorthy, R. R., 12 Nov 2013, In: PLoS ONE. 8, 11, e79183.Research output: Contribution to journal › Article › peer-review
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Levobetaxolol-induced up-regulation of retinal bFGF and CNTF mRNAs and preservation of retinal function against a photic-induced retinopathy
Agarwal, N., Martin, E., Krishnamoorthy, R. R., Landers, R., Wen, R., Krueger, S., Kapin, M. A. & Collier, R. J., 2002, In: Experimental eye research. 74, 4, p. 445-453 9 p.Research output: Contribution to journal › Article › peer-review
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Hypoxia augments TNF-α-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes
Desai, D., He, S., Yorio, T., Krishnamoorthy, R. R. & Prasanna, G., 4 Jun 2004, In: Biochemical and Biophysical Research Communications. 318, 3, p. 642-648 7 p.Research output: Contribution to journal › Article › peer-review
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Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy
Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., 1 Jun 2015, In: Stem Cells. 33, 6, p. 1743-1758 16 p.Research output: Contribution to journal › Article › peer-review
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Neuroprotective effects of transcription factor brn3b in an ocular hypertension rat model of glaucoma
Stankowska, D. L., Minton, A. Z., Rutledge, M. A., Mueller, B. H., Phatak, N. R., He, S., Ma, H. Y., Forster, M. J., Yorio, T. & Krishnamoorthy, R. R., 2015, In: Investigative Ophthalmology and Visual Science. 56, 2, p. 893-907 15 p.Research output: Contribution to journal › Article › peer-review
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Targets of neuroprotection in glaucoma
He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. R. & Yorio, T., 1 Jan 2018, In: Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.Research output: Contribution to journal › Article › peer-review
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Elimination of autofluorescence background from fluorescence tissue images by use of time-gated detection and the AzaDiOxaTriAngulenium (ADOTA) fluorophore
Rich, R. M., Stankowska, D. L., Maliwal, B. P., Sørensen, T. J., Laursen, B. W., Krishnamoorthy, R. R., Gryczynski, Z., Borejdo, J., Gryczynski, I. & Fudala, R., Feb 2013, In: Analytical and bioanalytical chemistry. 405, 6, p. 2065-2075 11 p.Research output: Contribution to journal › Article › peer-review
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Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells
Chaphalkar, R. M., Stankowska, D. L., He, S., Kodati, B., Phillips, N., Prah, J., Yang, S. & Krishnamoorthy, R. R., 1 Dec 2020, In: Scientific Reports. 10, 1, 3571.Research output: Contribution to journal › Article › peer-review
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Dexamethasone regulates endothelin-1 and endothelin receptors in human non-pigmented ciliary epithelial (HNPE) cells
Zhang, X., Krishnamoorthy, R. R., Prasanna, G., Narayan, S., Clark, A. & Yorio, T., 1 Mar 2003, In: Experimental eye research. 76, 3, p. 261-272 12 p.Research output: Contribution to journal › Article › peer-review
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Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: Implications for neuroprotection in glaucoma
Stankowska, D. L., Nam, M. H., Nahomi, R. B., Chaphalkar, R. M., Nandi, S. K., Fudala, R., Krishnamoorthy, R. R. & Nagaraj, R. H., 2019, In: Cell Death Discovery. 5, 1, 112.Research output: Contribution to journal › Article › peer-review
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Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma
McGrady, N. R., Minton, A. Z., Stankowska, D. L., He, S., Jefferies, H. B. & Krishnamoorthy, R. R., 1 Mar 2017, In: BMC Neuroscience. 18, 1, 27.Research output: Contribution to journal › Article › peer-review
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Photo-oxidative stress down-modulates the activity of nuclear factor- κB via involvement of caspase-1, leading to apoptosis of photoreceptor cells
Krishnamoorthy, R. R., Crawford, M. J., Chaturvedi, M. M., Jain, S. K., Aggarwal, B. B., Al-Ubaidi, M. R. & Agarwal, N., 5 Feb 1999, In: Journal of Biological Chemistry. 274, 6, p. 3734-3743 10 p.Research output: Contribution to journal › Article › peer-review
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Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in tissue
Rich, R. M., Gryczynski, I., Fudala, R., Borejdo, J., Stankowska, D. L., Krishnamoorthy, R. R., Raut, S., Maliwal, B. P., Shumilov, D., Doan, H. & Gryczynski, Z., 15 Mar 2014, In: Methods. 66, 2, p. 292-298 7 p.Research output: Contribution to journal › Article › peer-review
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Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction
Tchedre, K. T., Huang, R. Q., Dibas, A., Krishnamoorthy, R. R., Dillon, G. H. & Yorio, T., Nov 2008, In: Investigative Ophthalmology and Visual Science. 49, 11, p. 4993-5002 10 p.Research output: Contribution to journal › Article › peer-review
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A feed-forward regulation of endothelin receptors by c-Jun in human non-pigmented ciliary epithelial cells and retinal ganglion cells
Wang, J., Ma, H. Y., Krishnamoorthy, R. R., Yorio, T. & He, S., Sep 2017, In: PLoS ONE. 12, 9, e0185390.Research output: Contribution to journal › Article › peer-review
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Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells
Wang, Y., Ding, M., Chaudhari, S., Ding, Y., Yuan, J., Stankowska, D., He, S., Krishnamoorthy, R., Cunningham, J. T. & Ma, R., 3 May 2013, In: Journal of Biological Chemistry. 288, 18, p. 12852-12865 14 p.Research output: Contribution to journal › Article › peer-review
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Endothelin-1, endothelin A and B receptor expression and their pharmacological properties in GFAP negative human lamina cribrosa cells
Rao, V. R., Krishnamoorthy, R. R. & Yorio, T., Jun 2007, In: Experimental eye research. 84, 6, p. 1115-1124 10 p.Research output: Contribution to journal › Article › peer-review
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Retina-derived fetuin (RDF): Analysis by immunocytochemistry, reverse transcriptase-polymerase chain reaction and Southern blot
Sheedlo, H. J., Krishnamoorthy, R., Nelson, T., Agarwal, N., Liu, J., Roque, R. S., Wordinger, R. J., Jaynes, C. D., Brun-Zinkelnagel, A. M., O'Brian, P., Aschenbrenner, J. E. & Turner, J. E., Dec 1999, In: Current Eye Research. 19, 6, p. 465-471 7 p.Research output: Contribution to journal › Article › peer-review