• 1691 Citations
  • 21 h-Index
19972022

Research output per year

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Research Output

  • 1691 Citations
  • 21 h-Index
  • 38 Article
  • 4 Comment/debate
  • 2 Editorial
  • 2 Review article
2020
Open Access
2019
Open Access
2018

Targets of neuroprotection in glaucoma

He, S., Stankowska, D. L., Ellis, D. Z., Krishnamoorthy, R. R. & Yorio, T., 1 Jan 2018, In : Journal of Ocular Pharmacology and Therapeutics. 34, 1-2, p. 85-106 22 p.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Neuroprotective effects of curcumin on endothelin-1 mediated cell death in hippocampal neurons

Stankowska, D. L., Krishnamoorthy, V. R., Ellis, D. Z. & Krishnamoorthy, R. R., 28 May 2017, In : Nutritional Neuroscience. 20, 5, p. 273-283 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Upregulation of the endothelin A (ETA) receptor and its association with neurodegeneration in a rodent model of glaucoma

McGrady, N. R., Minton, A. Z., Stankowska, D. L., He, S., Jefferies, H. B. & Krishnamoorthy, R. R., 1 Mar 2017, In : BMC Neuroscience. 18, 1, 27.

Research output: Contribution to journalArticle

11 Scopus citations
2016
10 Scopus citations
9 Scopus citations
2015

Continuous non-cell autonomous reprogramming to generate retinal ganglion cells for glaucomatous neuropathy

Parameswaran, S., Dravid, S. M., Teotia, P., Krishnamoorthy, R. R., Qiu, F., Toris, C., Morrison, J. & Ahmad, I., 1 Jun 2015, In : Stem Cells. 33, 6, p. 1743-1758 16 p.

Research output: Contribution to journalArticle

9 Scopus citations

Endothelin-mediated changes in gene expression in isolated purified rat retinal ganglion cells

He, S., Park, Y. H., Yorio, T. & Krishnamoorthy, R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 10, p. 6144-6161 18 p.

Research output: Contribution to journalArticle

11 Scopus citations

Neuroprotective effects of transcription factor brn3b in an ocular hypertension rat model of glaucoma

Stankowska, D. L., Minton, A. Z., Rutledge, M. A., Mueller, B. H., Phatak, N. R., He, S., Ma, H. Y., Forster, M. J., Yorio, T. & Krishnamoorthy, R. R., 1 Jan 2015, In : Investigative Ophthalmology and Visual Science. 56, 2, p. 893-907 15 p.

Research output: Contribution to journalArticle

11 Scopus citations
3 Scopus citations
2014

Erratum: Characterization of a transformed rat retinal ganglion cell line (Brain Research Molecular Brain Research (2001) 86 (1-12))

Krishnamoorthy, R. R., Agarwal, P., Prasanna, G., Vopat, K., Lambert, W., Sheedlo, H. J., Pang, I. H., Shade, D., Wordinger, R. J., Yorio, T., Clark, A. F. & Agarwal, N., 28 Jan 2014, In : Brain Research. 1544, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in tissue

Rich, R. M., Gryczynski, I., Fudala, R., Borejdo, J., Stankowska, D. L., Krishnamoorthy, R. R., Raut, S., Maliwal, B. P., Shumilov, D., Doan, H. & Gryczynski, Z., 15 Mar 2014, In : Methods. 66, 2, p. 292-298 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2013

A forensic path to RGC-5 cell line identification: Lessons learned

Krishnamoorthy, R. R., Clark, A. F., Daudt, D., Vishwanatha, J. K. & Yorio, T., 30 Aug 2013, In : Investigative Ophthalmology and Visual Science. 54, 8, p. 5712-5719 8 p.

Research output: Contribution to journalEditorial

82 Scopus citations
42 Scopus citations

Involvement of AP-1 and C/EBPβ in upregulation of endothelin B (ETB) receptor expression in a rodent model of glaucoma

He, S., Minton, A. Z., Ma, H. Y., Stankowska, D. L., Sun, X. & Krishnamoorthy, R. R., 12 Nov 2013, In : PLoS ONE. 8, 11, e79183.

Research output: Contribution to journalArticle

9 Scopus citations
31 Scopus citations
2012

Endothelin b receptors contribute to retinal ganglion cell loss in a rat model of glaucoma

Minton, A. Z., Phatak, N. R., Stankowska, D. L., He, S., Ma, H. Y., Mueller, B. H., Jiang, M., Luedtke, R., Yang, S., Brownlee, C. & Krishnamoorthy, R. R., 20 Aug 2012, In : PLoS ONE. 7, 8, e43199.

Research output: Contribution to journalArticle

40 Scopus citations
2011

Endothelin, astrocytes and glaucoma

Prasanna, G., Krishnamoorthy, R. & Yorio, T., 1 Aug 2011, In : Experimental eye research. 93, 2, p. 170-177 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

Erratum: Protein profiling of human nonpigmented ciliary epithelium cell secretome: The differentiation factors characterization for retinal ganglion cell line (Journal of Biomedicine and Biotechnology 2011 (1))

Yang, M. H., Krishnamoorthy, R., Jong, S. B., Chu, P. Y., Yang, Y. H., Chen, W. C., Chen, S. C. J., Dibas, A., Chung, T. W. & Tyan, Y. C., 1 Dec 2011, In : Journal of Biomedicine and Biotechnology. 2011, 239089.

Research output: Contribution to journalComment/debate

Protein Profiling of human nonpigmented ciliary epithelium cell secretome: The differentiation factors characterization for retinal ganglion cell line

Chung, T. W., Yang, M. H., Krishnamoorthy, R. R., Jong, S. B., Chu, P. Y., Yang, Y. H., Chen, W. C., Chen, S. C. J., Dibas, A., Yorio, T. & Tyan, Y. C., 12 Oct 2011, In : Journal of Biomedicine and Biotechnology. 2011, 901329.

Research output: Contribution to journalArticle

6 Scopus citations
2010

Thrombin-induced endothelin-1 synthesis and secretion in retinal pigment epithelial cells is Rho kinase dependent

Narayan, S., Prasanna, G., Tchedre, K., Krishnamoorthy, R. & Yorio, T., 1 Oct 2010, In : Journal of Ocular Pharmacology and Therapeutics. 26, 5, p. 389-397 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
2008

Endothelin-1 mediated regulation of extracellular matrix collagens in cells of human lamina cribrosa

Rao, V. R., Krishnamoorthy, R. R. & Yorio, T., 1 Jun 2008, In : Experimental eye research. 86, 6, p. 886-894 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Role of the ETB receptor in retinal ganglion cell death in glaucoma

Krishnamoorthy, R., Rao, V. R., Dauphin, R., Prasanna, G., Johnson, C. & Yorio, T., 1 Jun 2008, In : Canadian Journal of Physiology and Pharmacology. 86, 6, p. 380-393 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Sigma-1 receptor regulation of voltage-gated calcium channels involves a direct interaction

Tchedre, K. T., Huang, R-Q., Dibas, A., Krishnamoorthy, R., Dillon, G. H. & Yorio, T., 1 Nov 2008, In : Investigative Ophthalmology and Visual Science. 49, 11, p. 4993-5002 10 p.

Research output: Contribution to journalArticle

99 Scopus citations
2007
19 Scopus citations
2005

Effect of elevated intraocular pressure on endothelin-1 in a rat model of glaucoma

Prasanna, G., Hulet, C., Desai, D., Krishnamoorthy, R. R., Narayan, S., Brun, A. M., Suburo, A. M. & Yorio, T., 1 Jan 2005, In : Pharmacological Research. 51, 1, p. 41-50 10 p.

Research output: Contribution to journalArticle

77 Scopus citations

Serum deprivation induces apoptotic cell death of transformed rat retinal ganglion cells via mitochondrial signaling pathways

Charles, I., Khalyfa, A., Kumar, D. M., Krishnamoorthy, R. R., Roque, R. S., Cooper, N. & Agarwal, N., 1 Apr 2005, In : Investigative Ophthalmology and Visual Science. 46, 4, p. 1330-1338 9 p.

Research output: Contribution to journalArticle

80 Scopus citations
2004
44 Scopus citations
2003

Dexamethasone regulates endothelin-1 and endothelin receptors in human non-pigmented ciliary epithelial (HNPE) cells

Zhang, X., Krishnamoorthy, R. R., Prasanna, G., Narayan, S., Clark, A. & Yorio, T., 1 Mar 2003, In : Experimental eye research. 76, 3, p. 261-272 12 p.

Research output: Contribution to journalArticle

26 Scopus citations
51 Scopus citations

Eyeing endothelins: A cellular perspective

Prasanna, G., Narayan, S., Krishnamoorthy, R. & Yorio, T., 1 Nov 2003, In : Molecular and Cellular Biochemistry. 253, 1-2, p. 71-88 18 p.

Research output: Contribution to journalReview article

45 Scopus citations

Regulation of Na,K-ATPase Expression by Endothelin-1 in Transformed Human Ciliary Non-Pigmented Epithelial (HNPE) Cells

Krishnamoorthy, R. R., Prasanna, G., Dauphin, R., Hulet, C., Agarwal, N. & Yorio, T., Oct 2003, In : Journal of Ocular Pharmacology and Therapeutics. 19, 5, p. 465-481 17 p.

Research output: Contribution to journalArticle

5 Scopus citations
2002

Endothelin: Is it a contributor to glaucoma pathophysiology?

Yorio, T., Krishnamoorthy, R. & Prasanna, G., 1 Jan 2002, In : Journal of Glaucoma. 11, 3, p. 259-270 12 p.

Research output: Contribution to journalReview article

127 Scopus citations

Human optic nerve head astrocytes as a target for endothelin-1

Prasanna, G., Krishnamoorthy, R., Clark, A. F., Wordinger, R. J. & Yorio, T., 5 Aug 2002, In : Investigative Ophthalmology and Visual Science. 43, 8, p. 2704-2713 10 p.

Research output: Contribution to journalArticle

105 Scopus citations

Levobetaxolol-induced up-regulation of retinal bFGF and CNTF mRNAs and preservation of retinal function against a photic-induced retinopathy

Agarwal, N., Martin, E., Krishnamoorthy, R. R., Landers, R., Wen, R., Krueger, S., Kapin, M. A. & Collier, R. J., 1 Jan 2002, In : Experimental eye research. 74, 4, p. 445-453 9 p.

Research output: Contribution to journalArticle

20 Scopus citations
2001

Bcl-2 overexpression protects photooxidative stress-induced apoptosis of photoreceptor cells via NF-κB preservation

Crawford, M. J., Krishnamoorthy, R. R., Rudick, V. L., Collier, R. J., Kapin, M., Aggarwal, B. B., Al-Ubaidi, M. R. & Agarwal, N., 1 Jan 2001, In : Biochemical and Biophysical Research Communications. 281, 5, p. 1304-1312 9 p.

Research output: Contribution to journalArticle

60 Scopus citations

Characterization of a transformed rat retinal ganglion cell line

Krishnamoorthy, R. R., Agarwal, P., Prasanna, G., Vopat, K., Lambert, W., Sheedlo, H. J., Pang, I. H., Shade, D., Wordinger, R. J., Yorio, T., Clark, A. F. & Agarwal, N., 31 Jan 2001, In : Molecular Brain Research. 86, 1-2, p. 1-12 12 p.

Research output: Contribution to journalArticle

299 Scopus citations

Erratum: Bcl-2 overexpression protects photooxidative stress-induced apoptosis of photoreceptor cells via NF-κB preservation (Biochemical and Biophysical Research Communications (2001) 281:5 (1304-1312))

Crawford, M. J., Krishnamoorthy, R., Rudick, V. L., Collier, R. J., Kapin, M., Aggarwal, B. B., Al-Ubaidi, M. R. & Agarwal, N., 14 Oct 2001, In : Biochemical and Biophysical Research Communications. 283, 2, 1 p.

Research output: Contribution to journalComment/debate

High cholesterol diet down regulates the activity of activator protein-1 but not nuclear factor-kappa B in rabbit brain

Kálmán, J., Kudchodkar, B. J., Krishnamoorthy, R., Dory, L., Lacko, A. G. & Agarwal, N., 16 Feb 2001, In : Life Sciences. 68, 13, p. 1495-1503 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2000

Endothelin-1 induces nitric oxide synthase-2 expression in human non-pigmented ciliary epithelial cells

Prasanna, G., Krishnamoorthy, R., Hulet, C., Zhang, H., Zhang, X. & Yorio, T., 1 Jan 2000, In : Experimental eye research. 71, 5, p. 535-539 5 p.

Research output: Contribution to journalEditorial

14 Scopus citations

Upregulation of CD44 expression in the retina during the rds degeneration

Krishnamoorthy, R., Agarwal, N. & Chaitin, M. H., 14 Apr 2000, In : Molecular Brain Research. 77, 1, p. 125-130 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
1999

Photo-oxidative stress down-modulates the activity of nuclear factor- κB via involvement of caspase-1, leading to apoptosis of photoreceptor cells

Krishnamoorthy, R., Crawford, M. J., Chaturvedi, M. M., Jain, S. K., Aggarwal, B. B., Al-Ubaidi, M. R. & Agarwal, N., 5 Feb 1999, In : Journal of Biological Chemistry. 274, 6, p. 3734-3743 10 p.

Research output: Contribution to journalArticle

130 Scopus citations

Retina-derived fetuin (RDF): Analysis by immunocytochemistry, reverse transcriptase-polymerase chain reaction and Southern blot

Sheedlo, H. J., Krishnamoorthy, R., Nelson, T., Agarwal, N., Liu, J., Roque, R. S., Wordinger, R. J., Jaynes, C. D., Brun-Zinkelnagel, A. M., O'Brian, P., Aschenbrenner, J. E. & Turner, J. E., Dec 1999, In : Current Eye Research. 19, 6, p. 465-471 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
1997
25 Scopus citations