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My research explores the growth and function of cranial tissues, particularly the structures involved in feeding. The biomechanical demands imposed by diet are known to affect chewing behavior and joint kinematics and, over time, the growth trajectories of the craniofacial skeleton and its associated soft tissues. By modulating diet, we are able to affect the overall growth of these tissues, bone quality in the jaws, integrity of the jaw joint (TMJ), dental occlusion, and masticatory muscle structure. I am particularly interested in how early life history events (such as weaning and dental eruption/replacement) affect feeding, growth, and adult morphological outcomes.
Current research themes include:
1) Variation in maturation rates among tissues of the masticatory complex and how this affects feeding performance and plasticity. What happens during the transition between infant-like suckling and adult-like chewing, and what are the structural and behavioral constraints that limit efficient feeding during early childhood?
2) The role of type I collagen in the growth of the craniofacial skeleton. How do collagen disorders, such as osteogenesis imperfecta, affect the facial phenotype? What behavioral and/or pharmaceutical interventions are effective in recovering the phenotype and function in these disorders?
Current research themes include:
1) Variation in maturation rates among tissues of the masticatory complex and how this affects feeding performance and plasticity. What happens during the transition between infant-like suckling and adult-like chewing, and what are the structural and behavioral constraints that limit efficient feeding during early childhood?
2) The role of type I collagen in the growth of the craniofacial skeleton. How do collagen disorders, such as osteogenesis imperfecta, affect the facial phenotype? What behavioral and/or pharmaceutical interventions are effective in recovering the phenotype and function in these disorders?
Education/Academic qualification
PhD in Anatomy, University of Missouri
BA in Anthropology, University of Texas at Austin
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Summer Opportunities in Anatomy Research (SOAR) Program
Menegaz, R. (PI), Maddux, S. (CoI) & Muchlinski, M. (CoI)
American Association of Anatomists
1/05/19 → 31/05/21
Project: Research
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Neurocranial growth in the OIM mouse model of osteogenesis imperfecta
Husain, T. S., Moore, J. C., Huston, L. A., Miller, C. A., Steele, A. T., Gonzales, L. A., Handler, E. K., Organ, J. M. & Menegaz, R. A., Mar 2024, In: Anatomical Record. 307, 3, p. 581-591 11 p.Research output: Contribution to journal › Article › peer-review
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Experimental Approaches to Musculoskeletal Function in Primates
Ravosa, M. J., Congdon, K. A. & Menegaz, R. A., 14 Jan 2013, A Companion to Paleoanthropology. Blackwell Publishing Ltd., p. 55-74 20 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
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Morphological variability in the inner ear of mice with osteogenesis imperfecta
Huston, L. A., Husain, T. S., Moore, J. C., Organ, J. M., Menegaz, R. A., Handler, E. K. & Gonzales, L. A., Mar 2024, In: Anatomical Record. 307, 3, p. 592-599 8 p.Research output: Contribution to journal › Article › peer-review
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More Challenging Diets Sustain Feeding Performance: Applications Toward the Captive Rearing of Wildlife
Rex Mitchell, D., Wroe, S., Ravosa, M. J. & Menegaz, R. A., 2021, In: Integrative Organismal Biology. 3, 1, obab030.Research output: Contribution to journal › Article › peer-review
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Indications of musculoskeletal health in deceased male individuals with lower-limb amputations: comparison to non-amputee and diabetic controls
Finco, M. G., Finnerty, C., Ngo, W. & Menegaz, R. A., Dec 2023, In: Scientific Reports. 13, 1, 8838.Research output: Contribution to journal › Article › peer-review