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Pankaj Chaudhary, PhD

  • 679 Citations
  • 17 h-Index
20052023

Research output per year

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Personal profile

Area of Expertise

My research focuses on various aspects of carcinogenesis, particularly the molecular mechanisms underlying triple-negative breast cancer growth and metastasis. A major focus of our work has been on investigating the molecular basis of Annexin A2 function in promoting triple-negative breast cancer metastasis and angiogenesis. Increased expression of Annexin A2 is commonly observed in triple-negative breast cancer. Our findings demonstrated that Annexin A2 overexpression is associated with racial variation and is a potential prognostic candidate for triple-negative breast cancer in African-American women. In addition, we identified Annexin A2 as a potential metastatic target protein in modulation triple-negative breast cancer tumor microenvironments. Currently, our laboratory is validating these findings and determining if Annexin A2 contributes to the disproportionate occurrence of triple-negative breast cancer and clinical outcome in African-American women. The long-term goal of our research is to develop improved therapeutic options for aggressive triple-negative breast cancer.

Education/Academic qualification

MS in Microbiology, Dr. R.M.L. Awadh University

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Projects

2/2 Langston University-UNTHSC Partnership for Cancer Research and Education Research Project 2

Chaudhary, P.

NCI: National Cancer Institute

20/09/18 → 31/08/22

Project: Research

2/2 Langston University-UNTHSC Partnership for Cancer Research and Education Research Project 2

Chaudhary, P.

NCI: National Cancer Institute

20/09/18 → 31/08/22

Project: Research

Investigating Serum Exosomal Annexin A2 in Promoting Aggressive TNBC in African American Women

Vishwanatha, J., Suzuki, S., Chaudhary, P. & Thyagarajan, S.

NCI: National Cancer Institute

1/07/17 → 30/06/23

Project: Research

Exosomal-Annexin A2 Promotes Metastasis in Triple-negative Breast Cancer

Chaudhary, P. & Mathew, P.

Intramural Research(UNTHSC)

1/06/17 → 31/05/18

Project: Research

Texas Center for Minority Health Education, Research and Outreach - Administrative Core

Vishwanatha, J., Jones, H., Chaudhary, P. & Ranjan, A.

NIMHD: Natl Institute on Minority Health

16/07/12 → 31/05/18

Project: Research

Research Output

  • 679 Citations
  • 17 h-Index
  • 23 Article
  • 6 Review article
  • 1 Comment/debate

Serum exosomal-annexin a2 is associated with african-American triple-negative breast cancer and promotes angiogenesis

Chaudhary, P., Gibbs, L. D., Maji, S., Lewis, C. M., Suzuki, S. & Vishwanatha, J. K., 28 Jan 2020, In : Breast Cancer Research. 22, 1, 11.

Research output: Contribution to journal › Article

Open Access

    • ANXA2 expression in African American triple-negative breast cancer patients

    Gibbs, L. D., Chaudhary, P., Mansheim, K., Hare, R. J., Mantsch, R. A. & Vishwanatha, J. K., 28 Feb 2019, In : Breast Cancer Research and Treatment. 174, 1, p. 113-120 8 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    In vivo imaging and biodistribution of near infrared dye loaded brain-metastatic-breast-cancer-cell-membrane coated polymeric nanoparticles

    Kumar, P., Treuren, T. V., Ranjan, A. P., Chaudhary, P. & Vishwanatha, J. K., 15 Apr 2019, In : Nanotechnology. 30, 26, 265101.

    Research output: Contribution to journal › Article

    • 5 Scopus citations

    Exosomal annexin II promotes angiogenesis and breast cancer metastasis

    Maji, S., Chaudhary, P., Akopova, I., Nguyen, P. M., Hare, R. J., Gryczynski, I. & Vishwanatha, J. K., 1 Jan 2017, In : Molecular Cancer Research. 15, 1, p. 93-105 13 p.

    Research output: Contribution to journal › Article

    • 62 Scopus citations

    Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity

    Awasthi, Y. C., Ramana, K. V., Chaudhary, P., Srivastava, S. K. & Awasthi, S., Oct 2017, In : Free Radical Biology and Medicine. 111, p. 235-243 9 p.

    Research output: Contribution to journal › Review article

    • 17 Scopus citations