Projects per year
Personal profile
Area of Expertise
My research focuses on various aspects of carcinogenesis, particularly the molecular mechanisms underlying triple-negative breast cancer growth and metastasis. A major focus of our work has been on investigating the molecular basis of Annexin A2 function in promoting triple-negative breast cancer metastasis and angiogenesis. Increased expression of Annexin A2 is commonly observed in triple-negative breast cancer. Our findings demonstrated that Annexin A2 overexpression is associated with racial variation and is a potential prognostic candidate for triple-negative breast cancer in African-American women. In addition, we identified Annexin A2 as a potential metastatic target protein in modulation triple-negative breast cancer tumor microenvironments. Currently, our laboratory is validating these findings and determining if Annexin A2 contributes to the disproportionate occurrence of triple-negative breast cancer and clinical outcome in African-American women. The long-term goal of our research is to develop improved therapeutic options for aggressive triple-negative breast cancer.
Education/Academic qualification
MS in Microbiology, Dr. R.M.L. Awadh University
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Projects
2/2 Langston University-UNTHSC Partnership for Cancer Research and Education Research Project 2
NCI: National Cancer Institute
20/09/18 → 31/08/22
Project: Research
2/2 Langston University-UNTHSC Partnership for Cancer Research and Education Research Project 2
NCI: National Cancer Institute
20/09/18 → 31/08/22
Project: Research
Investigating Serum Exosomal Annexin A2 in Promoting Aggressive TNBC in African American Women
Vishwanatha, J., Suzuki, S., Chaudhary, P. & Thyagarajan, S.
NCI: National Cancer Institute
1/07/17 → 30/06/23
Project: Research
2/2 Langston University-UNTHSC Partnership for Cancer Research and Education
Vishwanatha, J., Jones, H., Chaudhary, P. & BASHA, R. M.
1/09/18 → 31/08/19
Project: Research
Exosomal-Annexin A2 Promotes Metastasis in Triple-negative Breast Cancer
1/06/17 → 31/05/18
Project: Research
Research Output
Comparative analysis of racial differences in breast tumor microbiome
Thyagarajan, S., Zhang, Y., Thapa, S., Allen, M. S., Phillips, N., Chaudhary, P., Kashyap, M. V. & Vishwanatha, J. K., 1 Dec 2020, In : Scientific Reports. 10, 1, 14116.Research output: Contribution to journal › Article
Open Access
Erratum: Serum exosomal-annexin A2 is associated with African-American triple-negative breast cancer and promotes angiogenesis (Breast Cancer Research (2020) 22 (11) DOI: 10.1186/s13058-020-1251-8)
Chaudhary, P., Gibbs, L. D., Maji, S., Lewis, C. M., Suzuki, S. & Vishwanatha, J. K., 23 Mar 2020, In : Breast Cancer Research. 22, 1, 31.Research output: Contribution to journal › Comment/debate
Open Access
2
Scopus
citations
Serum exosomal-annexin a2 is associated with african-American triple-negative breast cancer and promotes angiogenesis
Chaudhary, P., Gibbs, L. D., Maji, S., Lewis, C. M., Suzuki, S. & Vishwanatha, J. K., 28 Jan 2020, In : Breast Cancer Research. 22, 1, 11.Research output: Contribution to journal › Article
Open Access
1
Scopus
citations
ANXA2 expression in African American triple-negative breast cancer patients
Gibbs, L. D., Chaudhary, P., Mansheim, K., Hare, R. J., Mantsch, R. A. & Vishwanatha, J. K., 28 Feb 2019, In : Breast Cancer Research and Treatment. 174, 1, p. 113-120 8 p.Research output: Contribution to journal › Article
4
Scopus
citations
In vivo imaging and biodistribution of near infrared dye loaded brain-metastatic-breast-cancer-cell-membrane coated polymeric nanoparticles
Kumar, P., Treuren, T. V., Ranjan, A. P., Chaudhary, P. & Vishwanatha, J. K., 15 Apr 2019, In : Nanotechnology. 30, 26, 265101.Research output: Contribution to journal › Article
6
Scopus
citations