Projects per year
Personal profile
URL
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Research Interests
Genomics, epigenomics, transcriptomics
Mitochondrial genetics and biology
Aging and Alzheimer's disease
Health disparities in complex disease
Preeclampsia
Area of Expertise
Dr. Nicole Phillips serves as the Project Lead for the Genomics Core in the Institute of Translational Research (ITR), and her team collaborates closely with Dr. Robert Barber (TCOM, Director of ITR Genomics Core). Her research program has several areas of focus, including:
- Application of multi-omics methods to further our understanding of the biological sources of health disparities in complex age-related diseases, such as Alzheimer's Disease (TARCC and NIH-funded);
- Studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes, and preeclampsia (in collaboration with Dr. Stella Goulopoulou at Loma Linda University, NIH-funded);
- Development of novel, nanopore-based sequencing applications for advancing detection of base modifications and human identification methods (NIJ-funded).
Education/Academic qualification
MS in Forensic Genetics, UNT Health Science Center
PhD in Molecular & Medical Genetics, UNT Health Science Center
BS in Biology, University of Houston
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Longitudinal validation of ret
Petersen, M. (PI) & Phillips, N. (CoI)
University of Rhode Island, Kingston
1/06/23 → 31/05/27
Project: Research
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Longitudinal validation of ret
Petersen, M. (PI) & Phillips, N. (CoI)
University of Rhode Island, Kingston
1/06/23 → 31/05/27
Project: Research
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DNA Typing Strategies for Iden
Zascavage, R. (PI) & Phillips, N. (CoI)
NIJ: National Institute of Justice
1/01/23 → 31/12/25
Project: Research
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Health & Aging Brain Study - H
O'Bryant, S. (PI), Hall, J. (CoI), Phillips, N. (CoI), Barber, R. (CoI) & Petersen, M. (CoI)
NIA: National Institute on Aging
1/09/22 → 31/08/27
Project: Research
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Mechanisms contributing to inhibition of retinal ganglion cell death by cell permeable peptain-1 under glaucomatous stress
Johnson, G. A., Kodati, B., Nahomi, R. B., Pham, J. H., Krishnamoorthy, V. R., Phillips, N. R., Krishnamoorthy, R. R., Nagaraj, R. H. & Stankowska, D. L., Dec 2024, In: Cell Death Discovery. 10, 1, 305.Research output: Contribution to journal › Article › peer-review
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Alzheimer's disease genetic risk: Top African American risk allele frequencies and genetic architecture among Mexican-, African-, and non-Hispanic White Americans
for the HABS-HD Study Team, 1 Apr 2025, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 11, 2, e70124.Research output: Contribution to journal › Article › peer-review
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Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells
Gardner, J. J., Cushen, S. C., Oliveira da Silva, R. D. N., Bradshaw, J. L., Hula, N., Gorham, I. K., Tucker, S. M., Zhou, Z., Cunningham, R. L., Phillips, N. R. & Goulopoulou, S., Jun 2024, In: American Journal of Physiology - Cell Physiology. 326, 6, p. C1776-C1788Research output: Contribution to journal › Article › peer-review
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Religiosity, Religious Beliefs, and Cognitive Impairment Among Black and White Men With Modest Incomes
Bruce, M. A., Beech, B. M., Marshall, G., Phillips, N., Jones, H. P., Pettigrew, C., Bowie, J. V., Whitfield, K. E. & Thorpe, R. J., Mar 2025, In: Journal of Aging and Health. 37, 3-4_suppl, p. 9S-21SResearch output: Contribution to journal › Article › peer-review
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Top Alzheimer's disease risk allele frequencies differ in HABS-HD Mexican- versus Non-Hispanic White Americans
Housini, M., Zhou, Z., Gutierrez, J., Rao, S., Jomaa, R., Subasinghe, K., Reid, D. M., Silzer, T., Phillips, N., O'Bryant, S. & Barber, R. C., 1 Oct 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 4, e12518.Research output: Contribution to journal › Article › peer-review