Projects per year
Personal profile
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Research Interests
Genomics, epigenomics, transcriptomics
Mitochondrial genetics and biology
Aging and Alzheimer's disease
Health disparities in complex disease
Preeclampsia
Area of Expertise
Dr. Nicole Phillips serves as the Project Lead for the Genomics Core in the Institute of Translational Research (ITR), and her team collaborates closely with Dr. Robert Barber (TCOM, Director of ITR Genomics Core). Her research program has several areas of focus, including:
- Application of multi-omics methods to further our understanding of the biological sources of health disparities in complex age-related diseases, such as Alzheimer's Disease (TARCC and NIH-funded);
- Studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes, and preeclampsia (in collaboration with Dr. Stella Goulopoulou at Loma Linda University, NIH-funded);
- Development of novel, nanopore-based sequencing applications for advancing detection of base modifications and human identification methods (NIJ-funded).
Education/Academic qualification
MS in Forensic Genetics, UNT Health Science Center
PhD in Molecular & Medical Genetics, UNT Health Science Center
BS in Biology, University of Houston
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Collaborations and top research areas from the last five years
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Longitudinal validation of ret
Petersen, M. (PI) & Phillips, N. (CoI)
University of Rhode Island, Kingston
1/06/23 → 31/05/27
Project: Research
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Longitudinal validation of ret
Petersen, M. (PI) & Phillips, N. (CoI)
University of Rhode Island, Kingston
1/06/23 → 31/05/27
Project: Research
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DNA Typing Strategies for Iden
Zascavage, R. (PI) & Phillips, N. (CoI)
NIJ: National Institute of Justice
1/01/23 → 31/12/25
Project: Research
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Health & Aging Brain Study - H
O'Bryant, S. (PI), Hall, J. (CoI), Phillips, N. (CoI), Barber, R. (CoI) & Petersen, M. (CoI)
NIA: National Institute on Aging
1/09/22 → 31/08/27
Project: Research
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Epigenetic Risk Factors for AD
Barber, R. (PI), Johnson, L. (CoI), Phillips, N. (CoI), Nandy, R. (CoI) & Zhou, Z. (CoI)
NIA: National Institute on Aging
15/09/21 → 31/05/26
Project: Research
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Maternal and fetal mitochondrial gene dysregulation in hypertensive disorders of pregnancy
Ricci, C. A., Reid, D. M., Sun, J., Santillan, D. A., Santillan, M. K., Phillips, N. R. & Goulopoulou, S., 2023, In: Physiological Genomics. 55, 7, p. 275-285 11 p.Research output: Contribution to journal › Article › peer-review
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Top Alzheimer's disease risk allele frequencies differ in HABS-HD Mexican- versus Non-Hispanic White Americans
Housini, M., Zhou, Z., Gutierrez, J., Rao, S., Jomaa, R., Subasinghe, K., Reid, D. M., Silzer, T., Phillips, N., O'Bryant, S. & Barber, R. C., 1 Oct 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 4, e12518.Research output: Contribution to journal › Article › peer-review
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Influence of Diet on Reproducible Corticosterone Levels in a Mouse Model of Maternal Separation with Early Weaning
Choe, J. Y., Donkor, M., Thorpe, R. J., Allen, M. S., Phillips, N. R. & Jones, H. P., Jul 2024, In: Life. 14, 7, 880.Research output: Contribution to journal › Article › peer-review
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Internal validation of human mitochondrial DNA quantification using real-time PCR
Sprouse, M. L., Phillips, N. R., Kavlick, M. F. & Roby, R. K., Jul 2014, In: Journal of Forensic Sciences. 59, 4, p. 1049-1056 8 p.Research output: Contribution to journal › Article › peer-review
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Multiomics investigation of hypertension and white matter hyperintensi-ty as a source of vascular dementia or a comorbidity to alzheimer’s disease
Pathak, G. A., Barber, R. C. & Phillips, N. R., 2021, In: Current Alzheimer Research. 18, 2, p. 171-177 7 p.Research output: Contribution to journal › Article › peer-review