Projects per year
Personal profile
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Research Interests
Genomics, epigenomics, transcriptomics
Mitochondrial genetics and biology
Aging and Alzheimer's disease
Health disparities in complex disease
Preeclampsia
Area of Expertise
Dr. Nicole Phillips serves as the Project Lead for the Genomics Core in the Institute of Translational Research (ITR), and her team collaborates closely with Dr. Robert Barber (TCOM, Director of ITR Genomics Core). Her research program has several areas of focus, including:
- Application of multi-omics methods to further our understanding of the biological sources of health disparities in complex age-related diseases, such as Alzheimer's Disease (TARCC and NIH-funded);
- Studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes, and preeclampsia (in collaboration with Dr. Stella Goulopoulou at Loma Linda University, NIH-funded);
- Development of novel, nanopore-based sequencing applications for advancing detection of base modifications and human identification methods (NIJ-funded).
Education/Academic qualification
MS in Forensic Genetics, UNT Health Science Center
PhD in Molecular & Medical Genetics, UNT Health Science Center
BS in Biology, University of Houston
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Collaborations and top research areas from the last five years
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Longitudinal validation of ret
Petersen, M. (PI) & Phillips, N. (CoI)
University of Rhode Island, Kingston
1/06/23 → 31/05/27
Project: Research
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Longitudinal validation of ret
Petersen, M. (PI) & Phillips, N. (CoI)
University of Rhode Island, Kingston
1/06/23 → 31/05/27
Project: Research
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Health & Aging Brain Study - H
O'Bryant, S. (PI), Hall, J. (CoI), Phillips, N. (CoI), Barber, R. (CoI) & Petersen, M. (CoI)
NIA: National Institute on Aging
1/09/22 → 31/08/27
Project: Research
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Epigenetic Risk Factors for AD
Barber, R. (PI), Johnson, L. (CoI), Phillips, N. (CoI), Nandy, R. (CoI) & Zhou, Z. (CoI)
NIA: National Institute on Aging
15/09/21 → 31/05/26
Project: Research
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Build Integrated Pathways to I
Jones, H. (PI), Phillips, N. (CoI), Barber, R. (CoI) & Basha, R. (CoI)
Xavier University of Louisiana
1/09/20 → 30/06/25
Project: Research
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Alzheimer's Disease Genotype Frequencies Differ in Top Risk Alleles Between Mexican Americans and Non-Hispanic Whites in HABLE Cohort
Housini, M., Rao, S. R., Phillips, N., O'Bryant, S. E. & Barber, R., Dec 2022, In: Alzheimer's and Dementia. 18, S5, e067346.Research output: Contribution to journal › Comment/debate
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Optimization of primer-specific filter metrics for the assessment of mitochondrial DNA sequence data
Curtis, P. C., Thomas, J. L., Phillips, N. R. & Roby, R. K., Dec 2010, In: Mitochondrial DNA. 21, 6, p. 191-197 7 p.Research output: Contribution to journal › Article › peer-review
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Genetic analysis of 7 medieval skeletons from the Aragonese Pyrenees
Núnez, C., Sosa, C., Baeta, M., Geppert, M., Turnbough, M., Phillips, N., Casalod, Y., Bolea, M., Roby, R., Budowle, B. & Martínez-Jarreta, B., Jun 2011, In: Croatian Medical Journal. 52, 3, p. 336-343 8 p.Research output: Contribution to journal › Article › peer-review
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Mitochondrial tRNA methylation in Alzheimer's disease and progressive supranuclear palsy
Silzer, T. K., Pathak, G. A. & Phillips, N. R., 19 May 2020, In: BMC Medical Genomics. 13, 1, 71.Research output: Contribution to journal › Article › peer-review
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Sex differences in neurobehavioral consequences of methamphetamine exposure in adult mice
Davis, D. L., Metzger, D. B., Vann, P. H., Wong, J. M., Subasinghe, K. H., Garlotte, I. K., Phillips, N. R., Shetty, R. A., Forster, M. J. & Sumien, N., Jul 2022, In: Psychopharmacology. 239, 7, p. 2331-2349 19 p.Research output: Contribution to journal › Article › peer-review