Projects per year
Personal profile
Area of Expertise
I first arrived at UNTHSC in 2007 as a Masters student in the Forensic Genetics Program, working extensively in research on expert systems and software development for the field. Upon graduating in 2009, and having found a love for research, I decided to pursue a PhD in Molecular Genetics, which was conferred in December of 2013. Throughout my experience at UNTHSC as a student and postdoctoral fellow, my research interests evolved. With my roots in forensic genetics, I began studying genetics of age-related, complex disease. In 2016, I returned to UNTHSC as a faculty member and have established a diverse research program.
Our laboratory has a several areas of interest:
1) studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes and preeclampsia (in collaboration with Dr. Stella Goulopoulou);
2) genetic aspects of pain and pain management, as the Director for Genomic Research for PRECISION Texas;
3) genetic risk for age-related disease and comorbidity patterns, via genome-wide genotyping, methylation profiling, and data mining.
Our laboratory has a several areas of interest:
1) studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes and preeclampsia (in collaboration with Dr. Stella Goulopoulou);
2) genetic aspects of pain and pain management, as the Director for Genomic Research for PRECISION Texas;
3) genetic risk for age-related disease and comorbidity patterns, via genome-wide genotyping, methylation profiling, and data mining.
Education/Academic qualification
MS in Forensic Genetics, UNT Health Science Center
PhD in Molecular & Medical Genetics, UNT Health Science Center
BS in Biology, University of Houston
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Projects
Texas Center of Minority Health, Education, Research and Outreach - Admin Suppliment
Vishwanatha, J., Phillips, N., Barber, R. & Zhou, Z.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
Epigenetic Risk Factors for Early Age at Onset of Alzheimer¿s & MCI Among Non-Caribbean Hispanics
Barber, R., Phillips, N. & Zhou, Z.
22/08/18 → 31/08/20
Project: Research
The Osteopathic Approach to Chronic Pain Management: Assessing its Biopsychosocial Processes and Relationships to Clinical Outcomes
Licciardone, J., Phillips, N. & Aryal, S.
American Osteopathic Association
1/09/17 → 31/08/19
Project: Research
Nanosensing of Oxidized Cell-free mtDNA: Biomarkers of Inflammation and Mitochondrial Dysfunction
Phillips, N., Planz, J. & Goulopoulou, S.
1/06/17 → 31/05/18
Project: Research
Research Output
Cell-free mitochondrial DNA increases in maternal circulation during healthy pregnancy: A prospective, longitudinal study
Cushen, S. C., Sprouse, M. L., Blessing, A., Sun, J., Jarvis, S. S., Okada, Y., Fu, Q., Romero, S. A., Phillips, N. R. & Goulopoulou, S., Feb 2020, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 2, p. R445-R452Research output: Contribution to journal › Article
1
Scopus
citations
Comparative analysis of racial differences in breast tumor microbiome
Thyagarajan, S., Zhang, Y., Thapa, S., Allen, M. S., Phillips, N., Chaudhary, P., Kashyap, M. V. & Vishwanatha, J. K., 1 Dec 2020, In : Scientific Reports. 10, 1, 14116.Research output: Contribution to journal › Article
Open Access
Differentiation of Hispanic biogeographic ancestry with 80 ancestry informative markers
Setser, C. H., Planz, J. V., Barber, R. C., Phillips, N. R., Chakraborty, R. & Cross, D. S., 1 Dec 2020, In : Scientific Reports. 10, 1, 7745.Research output: Contribution to journal › Article
Open Access
Endothelin-1 Mediated Decrease in Mitochondrial Gene Expression and Bioenergetics Contribute to Neurodegeneration of Retinal Ganglion Cells
Chaphalkar, R. M., Stankowska, D. L., He, S., Kodati, B., Phillips, N., Prah, J., Yang, S. & Krishnamoorthy, R. R., 1 Dec 2020, In : Scientific Reports. 10, 1, 3571.Research output: Contribution to journal › Article
Open Access
1
Scopus
citations
Mitochondrial tRNA methylation in Alzheimer's disease and progressive supranuclear palsy
Silzer, T. K., Pathak, G. A. & Phillips, N. R., 19 May 2020, In : BMC Medical Genomics. 13, 1, 71.Research output: Contribution to journal › Article
Open Access