Projects per year
Personal profile
Area of Expertise
I first arrived at UNTHSC in 2007 as a Masters student in the Forensic Genetics Program, working extensively in research on expert systems and software development for the field. Upon graduating in 2009, and having found a love for research, I decided to pursue a PhD in Molecular Genetics, which was conferred in December of 2013. Throughout my experience at UNTHSC as a student and postdoctoral fellow, my research interests evolved. With my roots in forensic genetics, I began studying genetics of age-related, complex disease. In 2016, I returned to UNTHSC as a faculty member and have established a diverse research program.
Our laboratory has a several areas of interest:
1) studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes and preeclampsia (in collaboration with Dr. Stella Goulopoulou);
2) genetic aspects of pain and pain management, as the Director for Genomic Research for PRECISION Texas;
3) genetic risk for age-related disease and comorbidity patterns, via genome-wide genotyping, methylation profiling, and data mining.
Our laboratory has a several areas of interest:
1) studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes and preeclampsia (in collaboration with Dr. Stella Goulopoulou);
2) genetic aspects of pain and pain management, as the Director for Genomic Research for PRECISION Texas;
3) genetic risk for age-related disease and comorbidity patterns, via genome-wide genotyping, methylation profiling, and data mining.
Education/Academic qualification
PhD in Molecular & Medical Genetics, UNT Health Science Center
Award Date: 1 Jan 2002
MS in Forensic Genetics, UNT Health Science Center
Award Date: 1 Jan 2001
BS in Biology, University of Houston
Award Date: 1 Jan 2000
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Projects
Epigenetic Risk Factors for Early Age at Onset of Alzheimer¿s & MCI Among Non-Caribbean Hispanics
Barber, R., Phillips, N. & Zhou, Z.
22/08/18 → 31/08/20
Project: Research
Texas Center of Minority Health, Education, Research and Outreach - Admin Suppliment
Vishwanatha, J., Phillips, N., Barber, R. & Zhou, Z.
NIMHD: Natl Institute on Minority Health
23/09/17 → 31/05/22
Project: Research
Nanosensing of Oxidized Cell-free mtDNA: Biomarkers of Inflammation and Mitochondrial Dysfunction
Phillips, N., Planz, J. & Goulopoulou, S.
1/06/17 → 31/05/18
Project: Research
Research Output
Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer
for the Alzheimer's Disease Neuroimaging Initiative, Breast and Prostate Cancer Cohort Consortium, and Alzheimer's Disease Genetics Consortium, 1 Jan 2020, In : Alzheimer's and Dementia. 16, 1, p. 162-177 16 p.Research output: Contribution to journal › Article
Open Access
Circulating mitochondrial DNA: New indices of type 2 diabetes-related cognitive impairment in Mexican Americans
Silzer, T., Barber, R., Sun, J., Pathak, G., Johnson, L., O’Bryant, S. & Phillips, N., Mar 2019, In : PLoS ONE. 14, 3, e0213527.Research output: Contribution to journal › Article
Open Access
3
Scopus
citations
Genome-Wide Methylation of Mild Cognitive Impairment in Mexican Americans Highlights Genes Involved in Synaptic Transport, Alzheimer's Disease-Precursor Phenotypes, and Metabolic Morbidities
Pathak, G. A., Silzer, T. K., Sun, J., Zhou, Z., Daniel, A. A., Johnson, L., O'Bryant, S., Phillips, N. R. & Barber, R. C., 1 Jan 2019, In : Journal of Alzheimer's Disease. 72, 3, p. 733-749 17 p.Research output: Contribution to journal › Article
Etiology of type 2 diabetes and Alzheimer's disease: Exploring the mitochondria
Silzer, T. K. & Phillips, N. R., Nov 2018, In : Mitochondrion. 43, p. 16-24 9 p.Research output: Contribution to journal › Review article
10
Scopus
citations
The Pain Registry for Epidemiological, Clinical, and interventional Studies and Innovation (PRECISION): Registry overview and protocol for a propensity score-matched study of opioid prescribing in patients with low back pain
Licciardone, J. C., Gatchel, R. J., Phillips, N. & Aryal, S., 1 Jan 2018, In : Journal of Pain Research. 11, p. 1751-1760 10 p.Research output: Contribution to journal › Article
4
Scopus
citations