• 149 Citations
  • 7 h-Index
20092020

Research output per year

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Personal profile

Area of Expertise

I first arrived at UNTHSC in 2007 as a Masters student in the Forensic Genetics Program, working extensively in research on expert systems and software development for the field. Upon graduating in 2009, and having found a love for research, I decided to pursue a PhD in Molecular Genetics, which was conferred in December of 2013. Throughout my experience at UNTHSC as a student and postdoctoral fellow, my research interests evolved. With my roots in forensic genetics, I began studying genetics of age-related, complex disease. In 2016, I returned to UNTHSC as a faculty member and have established a diverse research program.
Our laboratory has a several areas of interest:
1) studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes and preeclampsia (in collaboration with Dr. Stella Goulopoulou);
2) genetic aspects of pain and pain management, as the Director for Genomic Research for PRECISION Texas;
3) genetic risk for age-related disease and comorbidity patterns, via genome-wide genotyping, methylation profiling, and data mining.

Education/Academic qualification

MS in Forensic Genetics, UNT Health Science Center

PhD in Molecular & Medical Genetics, UNT Health Science Center

BS in Biology, University of Houston

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Projects

Research Output

  • 149 Citations
  • 7 h-Index
  • 15 Article
  • 2 Review article

Cell-free mitochondrial DNA increases in maternal circulation during healthy pregnancy: A prospective, longitudinal study

Cushen, S. C., Sprouse, M. L., Blessing, A., Sun, J., Jarvis, S. S., Okada, Y., Fu, Q., Romero, S. A., Phillips, N. R. & Goulopoulou, S., Feb 2020, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 318, 2, p. R445-R452

Research output: Contribution to journalArticle

  • 1 Scopus citations

    Differentiation of Hispanic biogeographic ancestry with 80 ancestry informative markers

    Setser, C. H., Planz, J. V., Barber, R. C., Phillips, N. R., Chakraborty, R. & Cross, D. S., 1 Dec 2020, In : Scientific Reports. 10, 1, 7745.

    Research output: Contribution to journalArticle

    Open Access
  • Open Access
  • Mitochondrial tRNA methylation in Alzheimer's disease and progressive supranuclear palsy

    Silzer, T. K., Pathak, G. A. & Phillips, N. R., 19 May 2020, In : BMC Medical Genomics. 13, 1, 71.

    Research output: Contribution to journalArticle

    Open Access
  • Two-stage Bayesian GWAS of 9576 individuals identifies SNP regions that are targeted by miRNAs inversely expressed in Alzheimer's and cancer

    for the Alzheimer's Disease Neuroimaging Initiative, Breast and Prostate Cancer Cohort Consortium, and Alzheimer's Disease Genetics Consortium, 1 Jan 2020, In : Alzheimer's and Dementia. 16, 1, p. 162-177 16 p.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations