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Genomics, epigenomics, transcriptomics

Mitochondrial genetics and biology

Aging and Alzheimer's disease

Health disparities in complex disease

Preeclampsia

Dr. Nicole Phillips serves as the Project Lead for the Genomics Core in the Institute of Translational Research (ITR), and her team collaborates closely with Dr. Robert Barber (TCOM, Director of ITR Genomics Core). Her research program has several areas of focus, including:

1. Application of multi-omics methods to further our understanding of the biological sources of health disparities in complex age-related diseases, such as Alzheimer's Disease (TARCC and NIH-funded);
2. Studies of mitochondrial DNA and mitochondrial function, in the context of various disease states such as Alzheimer’s disease, type 2 diabetes, and preeclampsia (in collaboration with Dr. Stella Goulopoulou at Loma Linda University, NIH-funded);
3. Development of novel, nanopore-based sequencing applications for advancing detection of base modifications and human identification methods (NIJ-funded).