Projects per year
Personal profile
Area of Expertise
My laboratory also works on other interventions for other conditions: sigma 1 compounds and chemobrain (brain dysfunction associated with chemotherapy), hyperbaric oxygen therapy to alleviate the symptoms of Alzheimer’s disease, and new antiaging therapy manipulating internal acidity. Identifying successful interventions and their interaction with factors such as genes and gender will lead to specialized recommendations to patients. Furthermore, it will allow us to determine specific mechanisms involved in positive outcomes leading to the development of therapeutic methods to ultimately improve health span of individuals.
Another project of the laboratory is to study the interaction of stroke and/or aging with drugs of abuse and to determine whether drug use makes individuals more susceptible to stroke and development of accelerated aging.
Education/Academic qualification
PhD in Biochemistry, Southern Methodist University
BS in Physiology, University of Mont Saint Aigna
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Network
Projects
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Training in the Neurobiology of Aging and Alzheimer's Disease
NIA: National Institute on Aging
1/05/19 → 30/04/24
Project: Research
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Training in the Neurobiology of Aging and Alzheimer's Disease
NIA: National Institute on Aging
1/05/19 → 30/04/24
Project: Research
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Effects of Aging on Blood Vessels in the Cerebellar Vermis
Jin, K., Forster, M. & Sumien, N.
NIA: National Institute on Aging
1/04/19 → 31/01/21
Project: Research
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Post Stroke Cognitive Impairment: Mechanism and Therapy
Yang, S., Liu, R., Sumien, N. & Jin, K.
NINDS: Neurological Disorders & Stroke
1/02/19 → 31/01/24
Project: Research
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Using rodent behavioral models to identify substance abuse pharmacotherapies
Forster, M., Gatch, M., Sumien, N. & Shetty, R.
NIDA: National Institute on Drug Abuse
20/09/18 → 3/01/23
Project: Research
Research Output
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Apoe genotype-dependent response to antioxidant and exercise interventions on brain function
Chaudhari, K., Wong, J. M., Vann, P. H., Como, T., O’bryant, S. E. & Sumien, N., Jun 2020, In: Antioxidants. 9, 6, p. 1-16 16 p., 553.Research output: Contribution to journal › Article › peer-review
Open Access -
Chronic Testosterone Deprivation Sensitizes the Middle-Aged Rat Brain to Damaging Effects of Testosterone Replacement
Smith, C., Contreras-Garza, J., Cunningham, R. L., Wong, J. M., Vann, P. H., Metzger, D., Kasanga, E., Oppong-Gyebi, A., Sumien, N. & Schreihofer, D., 1 Oct 2020, In: Neuroendocrinology. 110, 11-12, p. 914-928 15 p.Research output: Contribution to journal › Article › peer-review
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Effects of dietary 5-methoxyindole-2-carboxylic acid on brain functional recovery after ischemic stroke
Sumien, N., Huang, R., Chen, Z., Vann, P. H., Wong, J. M., Li, W., Yang, S., Forster, M. J. & Yan, L. J., 27 Jan 2020, In: Behavioural Brain Research. 378, 112278.Research output: Contribution to journal › Article › peer-review
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Estrogen receptor involvement in vascular cognitive impairment and vascular dementia pathogenesis and treatment
Nguyen, D. H., Cunningham, J. T. & Sumien, N., 2020, (Accepted/In press) In: GeroScience.Research output: Contribution to journal › Review article › peer-review
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Long-term HIV-1 Tat Expression in the Brain Led to Neurobehavioral, Pathological, and Epigenetic Changes Reminiscent of Accelerated Aging
Zhao, X., Fan, Y., Vann, P. H., Wong, J. M., Sumien, N. & He, J. J., 1 Feb 2020, In: Aging and Disease. 11, 1, p. 93-107 15 p.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations