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Research Output 1997 2019

  • 992 Citations
  • 18 h-Index
  • 40 Article
  • 2 Review article
  • 1 Chapter
2019

Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease

Churchill, M. J., Cantu, M. A., Kasanga, E. A., Moore, C., Salvatore, M. F. & Meshul, C. K., 21 Aug 2019, In : Neuroscience. 414, p. 8-27 20 p.

Research output: Contribution to journalArticle

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tyrosine 3-Monooxygenase
Parkinson Disease
Dopamine
3,4-Dihydroxyphenylacetic Acid

Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency

Salvatore, M. F., McInnis, T. R., Cantu, M. A., Apple, D. M. & Pruett, B. S., 1 Apr 2019, In : Molecular Neurobiology. 56, 4, p. 2728-2740 13 p.

Research output: Contribution to journalArticle

Tyrosine 3-Monooxygenase
Substantia Nigra
Dopamine
Hypokinesia
Corpus Striatum
2018
2 Citations (Scopus)

Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine

Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myöhänen, T. T., Rannanpää, S., Salvatore, M. F., Andressoo, J. O. & Piepponen, T. P., 1 Jan 2018, In : Neuropharmacology. 128, p. 221-230 10 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Amphetamine
Dopamine
Dopaminergic Neurons
Tyrosine 3-Monooxygenase
12 Citations (Scopus)

Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: Evidence from calorie restriction intervention

Salvatore, M. F., Terrebonne, J., Cantu, M. A., McInnis, T. R., Venable, K., Kelley, P., Kasanga, E. A., Latimer, B., Owens, C. L., Pruett, B. S., Yu, Y., Luedtke, R. T., Forster, M. J., Sumien, N. & Ingram, D. K., 1 Jan 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 1, p. 11-20 10 p.

Research output: Contribution to journalArticle

Corpus Striatum
Tyrosine 3-Monooxygenase
Dopamine
Locomotion
Hypokinesia
1 Citation (Scopus)
Phosphorylation
Methamphetamine
Tyrosine 3-Monooxygenase
Substantia Nigra
Dopamine
5 Citations (Scopus)

Tyrosine hydroxylase as a sentinel for central and peripheral tissue responses in Parkinson's progression: Evidence from clinical studies and neurotoxin models

Johnson, M. E., Salvatore, M. F., Maiolo, S. A. & Bobrovskaya, L., 1 Jun 2018, In : Progress in Neurobiology. 165-167, p. 1-25 25 p.

Research output: Contribution to journalReview article

Neurotoxins
Tyrosine 3-Monooxygenase
Parkinson Disease
Phosphorylation
Catecholamines
2017
1 Citation (Scopus)

Aging-related limit of exercise efficacy on motor decline

Arnold, J. C., Cantu, M. A., Kasanga, E. A., Nejtek, V. A., Papa, E. V., Bugnariu, N. & Salvatore, M. F., 1 Nov 2017, In : PLoS ONE. 12, 11, e0188538.

Research output: Contribution to journalArticle

exercise
Aging of materials
Exercise
Substantia Nigra
Rats
1 Citation (Scopus)

Ceftriaxone reduces L-dopa–induced dyskinesia severity in 6-hydroxydopamine parkinson's disease model

Chotibut, T., Meadows, S., Kasanga, E. A., McInnis, T., Cantu, M. A., Bishop, C. & Salvatore, M. F., 1 Nov 2017, In : Movement Disorders. 32, 11, p. 1547-1556 10 p.

Research output: Contribution to journalArticle

Dihydroxyphenylalanine
Ceftriaxone
Oxidopamine
Dyskinesias
Parkinson Disease
9 Citations (Scopus)

Phosphorylation at serine 31 targets tyrosine hydroxylase to vesicles for transport along microtubules

Jorge-Finnigan, A., Kleppe, R., Jung-KC, K., Ying, M., Marie, M., Rios-Mondragon, I., Salvatore, M. F., Saraste, J. & Martinez, A., 25 Aug 2017, In : Journal of Biological Chemistry. 292, 34, p. 14092-14107 16 p.

Research output: Contribution to journalArticle

Transport Vesicles
Phosphorylation
Tyrosine 3-Monooxygenase
Synucleins
Microtubules
2016
9 Citations (Scopus)
Tyrosine 3-Monooxygenase
Substantia Nigra
Rats
Glial Cell Line-Derived Neurotrophic Factor
Amino Acid Transport System X-AG
7 Citations (Scopus)

Initiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine

Salvatore, M. F., Terrebonne, J., Fields, V., Nodurft, D., Runfalo, C., Latimer, B. & Ingram, D. K., 1 Jan 2016, In : Neurobiology of Aging. 37, p. 192-207 16 p.

Research output: Contribution to journalArticle

Corpus Striatum
Hypokinesia
Locomotion
Dopamine
Substantia Nigra
17 Citations (Scopus)

Regulation of Tyrosine Hydroxylase Expression and Phosphorylation in Dopamine Transporter-Deficient Mice

Salvatore, M. F., Calipari, E. S. & Jones, S. R., 20 Jul 2016, In : ACS Chemical Neuroscience. 7, 7, p. 941-951 11 p.

Research output: Contribution to journalArticle

Dopamine Plasma Membrane Transport Proteins
Phosphorylation
Tyrosine 3-Monooxygenase
Dopamine
Biosynthesis
2014
27 Citations (Scopus)

Ceftriaxone increases glutamate uptake and reduces striatal tyrosine hydroxylase loss in 6-OHDA Parkinson's model

Chotibut, T., Davis, R. W., Arnold, J. C., Frenchek, Z., Gurwara, S., Bondada, V., Geddes, J. W. & Salvatore, M. F., 1 Jan 2014, In : Molecular Neurobiology. 49, 3, p. 1282-1292 11 p.

Research output: Contribution to journalArticle

Corpus Striatum
Ceftriaxone
Oxidopamine
Tyrosine 3-Monooxygenase
Glutamic Acid
8 Citations (Scopus)
Compliance
Rodentia
Aging of materials
Research Personnel
Exercise equipment
9 Citations (Scopus)
Norepinephrine Plasma Membrane Transport Proteins
Dihydroxyphenylalanine
Desipramine
Dyskinesias
Dopamine
2 Citations (Scopus)

Peripheral and cognitive signs: Delineating the significance of impaired catecholamine metabolism in Parkinsons disease progression

Salvatore, M. F., Disbrow, E. A. & Emborg, M. E., 1 Jan 2014, In : Journal of Neurochemistry. 131, 2, p. 129-133 5 p.

Research output: Contribution to journalReview article

Cognition Disorders
Metabolism
Catecholamines
Parkinson Disease
Disease Progression
19 Citations (Scopus)
Phosphorylation
Oxidopamine
Tyrosine 3-Monooxygenase
Dopamine
Recovery
2013
34 Citations (Scopus)

Chronic methamphetamine exposure produces a delayed, long-lasting memory deficit

North, A., Swant, J., Salvatore, M. F., Gamble-George, J., Prins, P., Butler, B., Mittal, M. K., Heltsley, R., Clark, J. T. & Khoshbouei, H., 1 May 2013, In : Synapse. 67, 5, p. 245-257 13 p.

Research output: Contribution to journalArticle

Methamphetamine
Memory Disorders
Short-Term Memory
Hippocampal CA1 Region
Neuronal Plasticity
18 Citations (Scopus)
Tyrosine 3-Monooxygenase
Substantia Nigra
Locomotion
Mixed Function Oxygenases
Dopamine
2012
16 Citations (Scopus)

Comprehensive profiling of dopamine regulation in substantia nigra and ventral tegmental area

Salvatore, M. F., Pruett, B. S., Dempsey, C. & Fields, V., 10 Aug 2012, In : Journal of Visualized Experiments. 66

Research output: Contribution to journalArticle

Ventral Tegmental Area
Substantia Nigra
Dopamine
Tyrosine 3-Monooxygenase
Vesicular Monoamine Transport Proteins
35 Citations (Scopus)
tyrosine 3-monooxygenase
Tyrosine 3-Monooxygenase
dopamine
Dopamine
Biosynthesis
28 Citations (Scopus)

Dopamine Transporter Loss in 6-OHDA Parkinson's Model Is Unmet by Parallel Reduction in Dopamine Uptake

Chotibut, T., Apple, D. M., Jefferis, R. & Salvatore, M. F., 29 Dec 2012, In : PLoS ONE. 7, 12, e52322.

Research output: Contribution to journalArticle

Dopamine Plasma Membrane Transport Proteins
Oxidopamine
dopamine
transporters
Dopamine
24 Citations (Scopus)

Social enrichment attenuates nigrostriatal lesioning and reverses motor impairment in a progressive 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease

Goldberg, N. R. S., Fields, V., Pflibsen, L., Salvatore, M. F. & Meshul, C. K., 1 Mar 2012, In : Neurobiology of Disease. 45, 3, p. 1051-1067 17 p.

Research output: Contribution to journalArticle

Parkinson Disease
Tyrosine 3-Monooxygenase
Putamen
Dopamine Plasma Membrane Transport Proteins
Neurons
19 Citations (Scopus)

Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser 19

Salvatore, M. F., Davis, R. W., Arnold, J. C. & Chotibut, T., 1 Apr 2012, In : Experimental Neurology. 234, 2, p. 428-436 9 p.

Research output: Contribution to journalArticle

Corpus Striatum
Tyrosine 3-Monooxygenase
Glutamic Acid
Phosphorylation
Parkinson Disease
2011
17 Citations (Scopus)

Biphasic dopamine regulation in mesoaccumbens pathway in response to non-contingent binge and escalating methamphetamine regimens in the Wistar rat

Keller, C. M., Salvatore, M. F., Pruett, B. S., Guerin, G. F. & Goeders, N. E., 1 Jun 2011, In : Psychopharmacology. 215, 3, p. 513-526 14 p.

Research output: Contribution to journalArticle

Methamphetamine
Wistar Rats
Dopamine
Tyrosine 3-Monooxygenase
Dopamine Plasma Membrane Transport Proteins
2010
10 Citations (Scopus)

GFR α-1 receptor expression in the aging nigrostriatal and mesoaccumbens pathways

Pruett, B. S. & Salvatore, M. F., 1 Nov 2010, In : Journal of Neurochemistry. 115, 3, p. 707-715 9 p.

Research output: Contribution to journalArticle

Substantia Nigra
Dopamine
Tyrosine 3-Monooxygenase
Aging of materials
Glial Cell Line-Derived Neurotrophic Factor
2009
39 Citations (Scopus)

Aging reveals a role for nigral tyrosine hydroxylase ser31 phosphorylation in locomotor activity generation

Salvatore, M. F., Pruett, B. S., Spann, S. L. & Dempsey, C., 1 Dec 2009, In : PLoS ONE. 4, 12, e8466.

Research output: Contribution to journalArticle

tyrosine 3-monooxygenase
Phosphorylation
Tyrosine 3-Monooxygenase
Substantia Nigra
Locomotion
24 Citations (Scopus)

Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system

Salvatore, M. F., Gerhardt, G. A., Dayton, R. D., Klein, R. L. & Stanford, J. A., 1 Sep 2009, In : Experimental Neurology. 219, 1, p. 197-207 11 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
gamma-Aminobutyric Acid
Dopamine
Corpus Striatum
Tyrosine 3-Monooxygenase
2008
35 Citations (Scopus)

Tau expression levels from various adeno-associated virus vector serotypes produce graded neurodegenerative disease states

Klein, R. L., Dayton, R. D., Tatom, J. B., Diaczynsky, C. G. & Salvatore, M. F., 1 Apr 2008, In : European Journal of Neuroscience. 27, 7, p. 1615-1625 11 p.

Research output: Contribution to journalArticle

Dependovirus
Neurodegenerative Diseases
Dopamine
Oxidopamine
Tauopathies
2007
10 Citations (Scopus)

Bilateral effects of unilateral intrastriatal GDNF on locomotor-excited and nonlocomotor-related striatal neurons in aged F344 rats

Stanford, J. A., Salvatore, M. F., Joyce, B. M., Zhang, H., Gash, D. M. & Gerhardt, G. A., 1 Jan 2007, In : Neurobiology of Aging. 28, 1, p. 156-165 10 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Corpus Striatum
Inbred F344 Rats
Neurons
Electrophysiology
11 Citations (Scopus)

Low dose alpha-methyl-para-tyrosine (AMPT) in the treatment of dystonia and dyskinesia

Ankenman, R. & Salvatore, M. F., 1 Jan 2007, In : Journal of Neuropsychiatry and Clinical Neurosciences. 19, 1, p. 65-69 5 p.

Research output: Contribution to journalArticle

alpha-Methyltyrosine
Dystonia
Dyskinesias
Tyrosine 3-Monooxygenase
Dopamine
34 Citations (Scopus)

Reduced plasma membrane surface expression of GLAST mediates decreased glutamate regulation in the aged striatum

Nickell, J., Salvatore, M. F., Pomerleau, F., Apparsundaram, S. & Gerhardt, G. A., 1 Nov 2007, In : Neurobiology of Aging. 28, 11, p. 1737-1748 12 p.

Research output: Contribution to journalArticle

Glutamic Acid
Cell Membrane
Inbred F344 Rats
Biotinylation
Amino Acid Transport System X-AG
2006
158 Citations (Scopus)

Point source concentration of GDNF may explain failure of phase II clinical trial

Salvatore, M. F., Ai, Y., Fischer, B., Zhang, A. M., Grondin, R. C., Zhang, Z., Gerhardt, G. A. & Gash, D. M., 1 Dec 2006, In : Experimental Neurology. 202, 2, p. 497-505 9 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Phase II Clinical Trials
Catheters
Putamen
Clinical Trials
2005
27 Citations (Scopus)

Neurochemical investigations of dopamine neuronal systems in iron-regulatory protein 2 (IRP-2) knockout mice

Salvatore, M. F., Fisher, B., Surgener, S. P., Gerhardt, G. A. & Rouault, T., 3 Oct 2005, In : Molecular Brain Research. 139, 2, p. 341-347 7 p.

Research output: Contribution to journalArticle

Iron Regulatory Protein 2
Knockout Mice
Dopamine
Serine
Tyrosine 3-Monooxygenase
2004
18 Citations (Scopus)

Prenatal cocaine exposure alters potassium-evoked dopamine release dynamics in rat striatum

Salvatore, M. F., Hudspeth, O., Arnold, L. E., Wilson, P. E., Stanford, J. A., MacTutus, C. F., Booze, R. M. & Gerhardt, G. A., 1 Jan 2004, In : Neuroscience. 123, 2, p. 481-490 10 p.

Research output: Contribution to journalArticle

Cocaine
Dopamine
Potassium
Dopamine Plasma Membrane Transport Proteins
Dopaminergic Neurons
75 Citations (Scopus)

Striatal GDNF administration increases tyrosine hydroxylase phosphorylation in the rat striatum and substantia nigra

Salvatore, M. F., Zhang, J. L., Large, D. M., Wilson, P. E., Gash, C. R., Thomas, T. C., Haycock, J. W., Bing, G., Stanford, J. A., Gash, D. M. & Gerhardt, G. A., 1 Jul 2004, In : Journal of Neurochemistry. 90, 1, p. 245-254 10 p.

Research output: Contribution to journalArticle

Glial Cell Line-Derived Neurotrophic Factor
Corpus Striatum
Phosphorylation
Tyrosine 3-Monooxygenase
Substantia Nigra
2003
53 Citations (Scopus)

Decreased plasma membrane expression of striatal dopamine transporter in aging

Salvatore, M. F., Apparsundaram, S. & Gerhardt, G. A., 1 Jan 2003, In : Neurobiology of Aging. 24, 8, p. 1147-1154 8 p.

Research output: Contribution to journalArticle

Corpus Striatum
Dopamine Plasma Membrane Transport Proteins
Cell Membrane
Ventral Tegmental Area
Tyrosine 3-Monooxygenase
2002
2 Citations (Scopus)

In Vivo voltammetry in drug abuse research

Salvatore, M. F., Hoffman, A. F., Burmeister, J. J. & Gerhardt, G. A., 1 Jan 2002, Methods in Drug Abuse Research: Cellular and Circuit Level Analyses. CRC Press, p. 87-110 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Substance-Related Disorders
Central Nervous System
Electrochemical Techniques
Nerve Tissue
Street Drugs
2001
82 Citations (Scopus)

Depolarization-stimulated catecholamine biosynthesis: Involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ

Salvatore, M. F., Waymire, J. C. & Haycock, J. W., 1 Nov 2001, In : Journal of Neurochemistry. 79, 2, p. 349-360 12 p.

Research output: Contribution to journalArticle

Phosphorylation
Biosynthesis
Depolarization
Tyrosine 3-Monooxygenase
Protein Kinases
2000
60 Citations (Scopus)

Stoichiometry of tyrosine hydroxylase phosphorylation in the nigrostriatal and mesolimbic systems in vivo: Effects of acute haloperidol and related compounds

Salvatore, M. F., Garcia-Espana, A., Goldstein, M., Deutch, A. Y. & Haycock, J. W., 11 Jul 2000, In : Journal of Neurochemistry. 75, 1, p. 225-232 8 p.

Research output: Contribution to journalArticle

Phosphorylation
Tyrosine 3-Monooxygenase
Haloperidol
Stoichiometry
Nucleus Accumbens
1999
17 Citations (Scopus)

Denervation of rabbit lacrimal gland increases levels of transferrin and unidentified tear proteins of 44 and 36 kDa

Salvatore, M. F., Pedroza, L. & Beuerman, R. W., 1 Jun 1999, In : Current Eye Research. 18, 6, p. 455-466 12 p.

Research output: Contribution to journalArticle

Lacrimal Apparatus
Denervation
Transferrin
Tears
Rabbits
1997
3 Citations (Scopus)

Analysis of rabbit tear fluid using capillary electrophoresis with UV or laser-induced fluorescence detection.

Varnell, R. J., Maitchouk, D. Y., Beuerman, R. W., Salvatore, M. F., Carlton, J. E. & Haag, A. M., 1 Jan 1997, In : Journal of capillary electrophoresis. 4, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Capillary electrophoresis
Capillary Electrophoresis
Electrophoresis
Tears
Buffers
14 Citations (Scopus)

Inhibition of nitric oxide synthase fails to disrupt the development of cholinergic fiber patches in the rat superior colliculus

Mize, R. R., Scheiner, C. A., Salvatore, M. F. & Cork, R. J., 1 Jan 1997, In : Developmental Neuroscience. 19, 3, p. 260-273 14 p.

Research output: Contribution to journalArticle

Cholinergic Fibers
Superior Colliculi
NADP
Nitric Oxide Synthase
Choline O-Acetyltransferase