Projects per year
Personal profile
Research Interests
Parkinson's disease, Aging, Dopamine regulation, Neurotransmission, Growth Factors
URL
Area of Expertise
I aim to understand the molecular basis for locomotor impairment in aging and Parkinson's disease. My immediate and long-term goals are to discover molecular, pharmacological, and non-invasive (exercise, calorie restriction) approaches that can target proteins associated with motor impairment, thereby reducing or eliminating locomotor impairment associated with aging and Parkinson’s disease.
Education/Academic qualification
PhD in Neuroscience, Louisiana State University Health Sciences Center
BA, Ohio Wesleyan University
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Collaborations and top research areas from the last five years
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Projects
- 5 Finished
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Translation of Evaluating Exercise-impact on Aging-related Motor Function Between Rats and Humans
Salvatore, M. (PI) & Bugnariu, N. (CoI)
1/01/17 → 30/06/18
Project: Research
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Targeting Nigral Tyrosine Hydroxylase to Improve Locomotion in Aging
Salvatore, M. (PI)
NIA: National Institute on Aging
5/01/15 → 31/03/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M. (PI) & SALVATORE, M. (CoPI)
1/04/12 → 30/09/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M. (PI), SALVATORE, M. F. (PI) & SALVATORE, M. F. (PI)
1/04/12 → 30/09/17
Project: Research
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Transient striatal GLT-1 blockade increases EAAC1 expression, glutamate reuptake, and decreases tyrosine hydroxylase phosphorylation at ser 19
Salvatore, M. F., Davis, R. W., Arnold, J. C. & Chotibut, T., Apr 2012, In: Experimental Neurology. 234, 2, p. 428-436 9 p.Research output: Contribution to journal › Article › peer-review
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Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine
Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myöhänen, T. T., Rannanpää, S., Salvatore, M. F., Andressoo, J. O. & Piepponen, T. P., Jan 2018, In: Neuropharmacology. 128, p. 221-230 10 p.Research output: Contribution to journal › Article › peer-review
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Ser31 tyrosine hydroxylase phosphorylation parallels differences in dopamine recovery in nigrostriatal pathway following 6-OHDA lesion
Salvatore, M. F., May 2014, In: Journal of Neurochemistry. 129, 3, p. 548-558 11 p.Research output: Contribution to journal › Article › peer-review
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Is there a Neurobiological Rationale for the Utility of the Iowa Gambling Task in Parkinson's Disease?
Salvatore, M. F., Soto, I., Alphonso, H., Cunningham, R., James, R. & Nejtek, V. A., 2021, In: Journal of Parkinson's Disease. 11, 2, p. 405-419 15 p.Research output: Contribution to journal › Review article › peer-review
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Social enrichment attenuates nigrostriatal lesioning and reverses motor impairment in a progressive 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease
Goldberg, N. R. S., Fields, V., Pflibsen, L., Salvatore, M. F. & Meshul, C. K., Mar 2012, In: Neurobiology of Disease. 45, 3, p. 1051-1067 17 p.Research output: Contribution to journal › Article › peer-review