Projects per year
Personal profile
Research Interests
Parkinson's disease, Aging, Dopamine regulation, Neurotransmission, Growth Factors
URL
Area of Expertise
I aim to understand the molecular basis for locomotor impairment in aging and Parkinson's disease. My immediate and long-term goals are to discover molecular, pharmacological, and non-invasive (exercise, calorie restriction) approaches that can target proteins associated with motor impairment, thereby reducing or eliminating locomotor impairment associated with aging and Parkinson’s disease.
Education/Academic qualification
PhD in Neuroscience, Louisiana State University Health Sciences Center
BA, Ohio Wesleyan University
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Collaborations and top research areas from the last five years
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Projects
- 5 Finished
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Translation of Evaluating Exercise-impact on Aging-related Motor Function Between Rats and Humans
Salvatore, M. (PI) & Bugnariu, N. (CoI)
1/01/17 → 30/06/18
Project: Research
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Targeting Nigral Tyrosine Hydroxylase to Improve Locomotion in Aging
Salvatore, M. (PI)
NIA: National Institute on Aging
5/01/15 → 31/03/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M. (PI), SALVATORE, M. F. (PI) & SALVATORE, M. F. (PI)
1/04/12 → 30/09/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M. (PI) & SALVATORE, M. (CoPI)
1/04/12 → 30/09/17
Project: Research
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Bilateral effects of unilateral GDNF administration on dopamine- and GABA-regulating proteins in the rat nigrostriatal system
Salvatore, M. F., Gerhardt, G. A., Dayton, R. D., Klein, R. L. & Stanford, J. A., Sep 2009, In: Experimental Neurology. 219, 1, p. 197-207 11 p.Research output: Contribution to journal › Article › peer-review
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GFR-α1 Expression in Substantia Nigra Increases Bilaterally following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss following 6-OHDA Nigrostriatal Lesion
Kasanga, E. A., Owens, C. L., Cantu, M. A., Richard, A. D., Davis, R. W., McDivitt, L. M., Blancher, B., Pruett, B. S., Tan, C., Gajewski, A., Manfredsson, F. P., Nejtek, V. A. & Salvatore, M. F., 16 Oct 2019, In: ACS Chemical Neuroscience. 10, 10, p. 4237-4249 13 p.Research output: Contribution to journal › Article › peer-review
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Initiation of calorie restriction in middle-aged male rats attenuates aging-related motoric decline and bradykinesia without increased striatal dopamine
Salvatore, M. F., Terrebonne, J., Fields, V., Nodurft, D., Runfalo, C., Latimer, B. & Ingram, D. K., 1 Jan 2016, In: Neurobiology of Aging. 37, p. 192-207 16 p.Research output: Contribution to journal › Article › peer-review
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Is there a Neurobiological Rationale for the Utility of the Iowa Gambling Task in Parkinson's Disease?
Salvatore, M. F., Soto, I., Alphonso, H., Cunningham, R., James, R. & Nejtek, V. A., 2021, In: Journal of Parkinson's Disease. 11, 2, p. 405-419 15 p.Research output: Contribution to journal › Review article › peer-review
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Depolarization-stimulated catecholamine biosynthesis: Involvement of protein kinases and tyrosine hydroxylase phosphorylation sites in situ
Salvatore, M. F., Waymire, J. C. & Haycock, J. W., 2001, In: Journal of Neurochemistry. 79, 2, p. 349-360 12 p.Research output: Contribution to journal › Article › peer-review