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Michael Salvatore, PhD

  • 1095 Citations
  • 20 h-Index
19972019

Research output per year

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Personal profile

Area of Expertise

I aim to understand the molecular basis for locomotor impairment in aging and Parkinson's disease. My immediate and long-term goals are to discover molecular, pharmacological, and non-invasive (exercise, calorie restriction) approaches that can target proteins associated with motor impairment, thereby reducing or eliminating locomotor impairment associated with aging and Parkinson’s disease.

Education/Academic qualification

PhD in Neuroscience, Louisiana State University Health Sciences Center

BA, Ohio Wesleyan University

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Projects

Increasing Nigral Tyrosine Hydroxylase Expression as a Mechanism of Exercise-Mediated Recovery: Evaluation in Toxin and Rat Parkinson's Disease Genetic Models

Salvatore, M.

Department of Defense

1/09/19 → 31/08/22

Project: Research

Translation of Evaluating Exercise-impact on Aging-related Motor Function Between Rats and Humans

Salvatore, M. & Bugnariu, N.

Intramural Research(UNTHSC)

1/01/17 → 30/06/18

Project: Research

Targeting Nigral Tyrosine Hydroxylase to Improve Locomotion in Aging

Salvatore, M.

NIA: National Institute on Aging

5/01/15 → 31/03/17

Project: Research

Targeting nigral tyrosine hydroxylase to improve locomotion in aging

Salvatore, M.

1/04/12 → 31/03/13

Project: Research

Research Output

  • 1095 Citations
  • 20 h-Index
  • 41 Article
  • 2 Review article
  • 1 Chapter

GFR-α1 Expression in Substantia Nigra Increases Bilaterally following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss following 6-OHDA Nigrostriatal Lesion

Kasanga, E. A., Owens, C. L., Cantu, M. A., Richard, A. D., Davis, R. W., McDivitt, L. M., Blancher, B., Pruett, B. S., Tan, C., Gajewski, A., Manfredsson, F. P., Nejtek, V. A. & Salvatore, M. F., 16 Oct 2019, In : ACS Chemical Neuroscience. 10, 10, p. 4237-4249 13 p.

Research output: Contribution to journal › Article

    • 1 Scopus citations

    Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease

    Churchill, M. J., Cantu, M. A., Kasanga, E. A., Moore, C., Salvatore, M. F. & Meshul, C. K., 21 Aug 2019, In : Neuroscience. 414, p. 8-27 20 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency

    Salvatore, M. F., McInnis, T. R., Cantu, M. A., Apple, D. M. & Pruett, B. S., 1 Apr 2019, In : Molecular Neurobiology. 56, 4, p. 2728-2740 13 p.

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine

    Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myöhänen, T. T., Rannanpää, S., Salvatore, M. F., Andressoo, J. O. & Piepponen, T. P., Jan 2018, In : Neuropharmacology. 128, p. 221-230 10 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: Evidence from calorie restriction intervention

    Salvatore, M. F., Terrebonne, J., Cantu, M. A., McInnis, T. R., Venable, K., Kelley, P., Kasanga, E. A., Latimer, B., Owens, C. L., Pruett, B. S., Yu, Y., Luedtke, R., Forster, M. J., Sumien, N. & Ingram, D. K., 1 Jan 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 1, p. 11-20 10 p.

    Research output: Contribution to journal › Article

    • 14 Scopus citations