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Personal profile

Area of Expertise

I aim to understand the molecular basis for locomotor impairment in aging and Parkinson's disease. My immediate and long-term goals are to discover molecular, pharmacological, and non-invasive (exercise, calorie restriction) approaches that can target proteins associated with motor impairment, thereby reducing or eliminating locomotor impairment associated with aging and Parkinson’s disease.

Education/Academic qualification

PhD in Neuroscience, LSU Health Sciences Center - New Orleans

BA, Ohio Wesleyan University

Fingerprint Dive into the research topics where Michael Salvatore is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Tyrosine 3-Monooxygenase Medicine & Life Sciences
Dopamine Medicine & Life Sciences
Corpus Striatum Medicine & Life Sciences
Substantia Nigra Medicine & Life Sciences
Phosphorylation Chemical Compounds
Parkinson Disease Medicine & Life Sciences
Glial Cell Line-Derived Neurotrophic Factor Medicine & Life Sciences
Dopamine Plasma Membrane Transport Proteins Medicine & Life Sciences

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Projects 2015 2018

Research Output 1997 2019

  • 982 Citations
  • 18 h-Index
  • 40 Article
  • 2 Review article
  • 1 Chapter

Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease

Churchill, M. J., Cantu, M. A., Kasanga, E. A., Moore, C., Salvatore, M. F. & Meshul, C. K., 21 Aug 2019, In : Neuroscience. 414, p. 8-27 20 p.

Research output: Contribution to journalArticleResearchpeer-review

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Tyrosine 3-Monooxygenase
Parkinson Disease
Dopamine
3,4-Dihydroxyphenylacetic Acid

Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency

Salvatore, M. F., McInnis, T. R., Cantu, M. A., Apple, D. M. & Pruett, B. S., 1 Apr 2019, In : Molecular Neurobiology. 56, 4, p. 2728-2740 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Tyrosine 3-Monooxygenase
Substantia Nigra
Dopamine
Hypokinesia
Corpus Striatum
2 Citations (Scopus)

Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine

Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myöhänen, T. T., Rannanpää, S., Salvatore, M. F., Andressoo, J. O. & Piepponen, T. P., 1 Jan 2018, In : Neuropharmacology. 128, p. 221-230 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Glial Cell Line-Derived Neurotrophic Factor
Amphetamine
Dopamine
Dopaminergic Neurons
Tyrosine 3-Monooxygenase
12 Citations (Scopus)

Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: Evidence from calorie restriction intervention

Salvatore, M. F., Terrebonne, J., Cantu, M. A., McInnis, T. R., Venable, K., Kelley, P., Kasanga, E. A., Latimer, B., Owens, C. L., Pruett, B. S., Yu, Y., Luedtke, R. T., Forster, M. J., Sumien, N. & Ingram, D. K., 1 Jan 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 1, p. 11-20 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Corpus Striatum
Tyrosine 3-Monooxygenase
Dopamine
Locomotion
Hypokinesia
1 Citation (Scopus)

Prolonged increase in ser31 tyrosine hydroxylase phosphorylation in substantia nigra following cessation of chronic methamphetamine

Salvatore, M. F., Nejtek, V. A. & Khoshbouei, H., 1 Jul 2018, In : NeuroToxicology. 67, p. 121-128 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Phosphorylation
Methamphetamine
Tyrosine 3-Monooxygenase
Substantia Nigra
Dopamine