Projects per year
Personal profile
Area of Expertise
I aim to understand the molecular basis for locomotor impairment in aging and Parkinson's disease. My immediate and long-term goals are to discover molecular, pharmacological, and non-invasive (exercise, calorie restriction) approaches that can target proteins associated with motor impairment, thereby reducing or eliminating locomotor impairment associated with aging and Parkinson’s disease.
Education/Academic qualification
PhD in Neuroscience, Louisiana State University Health Sciences Center
BA, Ohio Wesleyan University
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Dive into the research topics where Michael Salvatore is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
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Translation of Evaluating Exercise-impact on Aging-related Motor Function Between Rats and Humans
Salvatore, M. & Bugnariu, N.
1/01/17 → 30/06/18
Project: Research
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Targeting Nigral Tyrosine Hydroxylase to Improve Locomotion in Aging
NIA: National Institute on Aging
5/01/15 → 31/03/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M., SALVATORE, M. F. & SALVATORE, M. F.
1/04/12 → 30/09/17
Project: Research
Research output
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GFR-α1 Expression in Substantia Nigra Increases Bilaterally following Unilateral Striatal GDNF in Aged Rats and Attenuates Nigral Tyrosine Hydroxylase Loss following 6-OHDA Nigrostriatal Lesion
Kasanga, E. A., Owens, C. L., Cantu, M. A., Richard, A. D., Davis, R. W., McDivitt, L. M., Blancher, B., Pruett, B. S., Tan, C., Gajewski, A., Manfredsson, F. P., Nejtek, V. A. & Salvatore, M. F., 16 Oct 2019, In: ACS Chemical Neuroscience. 10, 10, p. 4237-4249 13 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Glatiramer Acetate Reverses Motor Dysfunction and the Decrease in Tyrosine Hydroxylase Levels in a Mouse Model of Parkinson's Disease
Churchill, M. J., Cantu, M. A., Kasanga, E. A., Moore, C., Salvatore, M. F. & Meshul, C. K., 21 Aug 2019, In: Neuroscience. 414, p. 8-27 20 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency
Salvatore, M. F., McInnis, T. R., Cantu, M. A., Apple, D. M. & Pruett, B. S., 1 Apr 2019, In: Molecular Neurobiology. 56, 4, p. 2728-2740 13 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Constitutive Ret signaling leads to long-lasting expression of amphetamine-induced place conditioning via elevation of mesolimbic dopamine
Kopra, J., Villarta-Aguilera, M., Savolainen, M., Weingerl, S., Myöhänen, T. T., Rannanpää, S., Salvatore, M. F., Andressoo, J. O. & Piepponen, T. P., Jan 2018, In: Neuropharmacology. 128, p. 221-230 10 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Dissociation of striatal dopamine and tyrosine hydroxylase expression from aging-related motor decline: Evidence from calorie restriction intervention
Salvatore, M. F., Terrebonne, J., Cantu, M. A., McInnis, T. R., Venable, K., Kelley, P., Kasanga, E. A., Latimer, B., Owens, C. L., Pruett, B. S., Yu, Y., Luedtke, R., Forster, M. J., Sumien, N. & Ingram, D. K., 1 Jan 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 1, p. 11-20 10 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations