Projects per year
Personal profile
Research Interests
Parkinson's disease, Aging, Dopamine regulation, Neurotransmission, Growth Factors
URL
Area of Expertise
I aim to understand the molecular basis for locomotor impairment in aging and Parkinson's disease. My immediate and long-term goals are to discover molecular, pharmacological, and non-invasive (exercise, calorie restriction) approaches that can target proteins associated with motor impairment, thereby reducing or eliminating locomotor impairment associated with aging and Parkinson’s disease.
Education/Academic qualification
PhD in Neuroscience, Louisiana State University Health Sciences Center
BA, Ohio Wesleyan University
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Collaborations and top research areas from the last five years
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Projects
- 5 Finished
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Translation of Evaluating Exercise-impact on Aging-related Motor Function Between Rats and Humans
Salvatore, M. (PI) & Bugnariu, N. (CoI)
1/01/17 → 30/06/18
Project: Research
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Targeting Nigral Tyrosine Hydroxylase to Improve Locomotion in Aging
Salvatore, M. (PI)
NIA: National Institute on Aging
5/01/15 → 31/03/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M. (PI), SALVATORE, M. F. (PI) & SALVATORE, M. F. (PI)
1/04/12 → 30/09/17
Project: Research
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Targeting nigral tyrosine hydroxylase to improve locomotion in aging
Salvatore, M. (PI) & SALVATORE, M. (CoPI)
1/04/12 → 30/09/17
Project: Research
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Tau expression levels from various adeno-associated virus vector serotypes produce graded neurodegenerative disease states
Klein, R. L., Dayton, R. D., Tatom, J. B., Diaczynsky, C. G. & Salvatore, M. F., Apr 2008, In: European Journal of Neuroscience. 27, 7, p. 1615-1625 11 p.Research output: Contribution to journal › Article › peer-review
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Establishing Equivalent Aerobic Exercise Parameters Between Early-Stage Parkinson's Disease and Pink1 Knockout Rats
Salvatore, M. F., Soto, I., Kasanga, E. A., James, R., Shifflet, M. K., Doshier, K., Little, J. T., John, J., Alphonso, H. M., Cunningham, J. T. & Nejtek, V. A., 2022, In: Journal of Parkinson's Disease. 12, 6, p. 1897-1915 19 p.Research output: Contribution to journal › Article › peer-review
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Exercise-Mediated Increase in Nigral Tyrosine Hydroxylase Is Accompanied by Increased Nigral GFR-α1 and EAAC1 Expression in Aging Rats
Arnold, J. C. & Salvatore, M. F., 17 Feb 2016, In: ACS Chemical Neuroscience. 7, 2, p. 227-239 13 p.Research output: Contribution to journal › Article › peer-review
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Striatal GDNF administration increases tyrosine hydroxylase phosphorylation in the rat striatum and substantia nigra
Salvatore, M. F., Zhang, J. L., Large, D. M., Wilson, P. E., Gash, C. R., Thomas, T. C., Haycock, J. W., Bing, G., Stanford, J. A., Gash, D. M. & Gerhardt, G. A., Jul 2004, In: Journal of Neurochemistry. 90, 1, p. 245-254 10 p.Research output: Contribution to journal › Article › peer-review
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Low dose alpha-methyl-para-tyrosine (AMPT) in the treatment of dystonia and dyskinesia
Ankenman, R. & Salvatore, M. F., 2007, In: Journal of Neuropsychiatry and Clinical Neurosciences. 19, 1, p. 65-69 5 p.Research output: Contribution to journal › Article › peer-review