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1980 …2019
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Research Output 1980 2019

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Article
2019

An elective course in lesbian, gay, bisexual, and transgender health and practice issues

Jann, M. W., Penzak, S., White, A. & Tatachar, A., 1 Jan 2019, In : American journal of pharmaceutical education. 83, 8, p. 1723-1731 9 p., 6967.

Research output: Contribution to journalArticle

Transgender Persons
Health
health
health care
learning
2015
21 Citations (Scopus)
Drug interactions
Tandem Mass Spectrometry
Chromatography
Drug Interactions
Mass spectrometry
2014
109 Citations (Scopus)

Benzodiazepines: A major component in unintentional prescription drug overdoses with opioid analgesics

Jann, M., Kennedy, W. K. & Lopez, G., Feb 2014, In : Journal of Pharmacy Practice. 27, 1, p. 5-16 12 p.

Research output: Contribution to journalArticle

Drug Overdose
Prescription Drugs
Benzodiazepines
Opioid Analgesics
Oxycodone
1 Citation (Scopus)

Unique collaboration between a private college of pharmacy and a private academic health system

Metzger, N., Paciullo, C., Chesson, M., Jann, M. W., Glascock, J., Emamifar, A. & Matthews, H. W., 1 Jan 2014, In : Hospital Pharmacy. 49, 7, p. 634-638 5 p.

Research output: Contribution to journalArticle

Health
Students
Education
Hospital Pharmacy Services
Pharmacy Students
2013
38 Citations (Scopus)
Warfarin
Metabolites
Tandem Mass Spectrometry
Chromatography
Mass spectrometry
2012
7 Citations (Scopus)

Lack of a pharmacokinetic drug-drug interaction with venlafaxine extended-release/indinavir and desvenlafaxine extended-release/indinavir

Jann, M. W., Spratlin, V., Momary, K., Zhang, H., Turner, D., Penzak, S. R., Wright, A. & VanDenBerg, C., 1 May 2012, In : European Journal of Clinical Pharmacology. 68, 5, p. 715-721 7 p.

Research output: Contribution to journalArticle

Indinavir
Drug Interactions
Pharmacokinetics
Pharmaceutical Preparations
Antidepressive Agents
2011
177 Citations (Scopus)

Maternal treatment with opioid analgesics and risk for birth defects

Broussard, C. S., Rasmussen, S. A., Reefhuis, J., Friedman, J. M., Jann, M. W., Riehle-Colarusso, T. & Honein, M. A., 1 Jan 2011, In : American Journal of Obstetrics and Gynecology. 204, 4, p. 314.e1-314.e11

Research output: Contribution to journalArticle

Opioid Analgesics
Odds Ratio
Mothers
Therapeutics
Women Physicians
2008
4 Citations (Scopus)

Disposition of D-serine in healthy adults

Tsai, G. E., Lane, H. Y., Vandenberg, C. M., Liu, Y. C., Tsai, P. & Jann, M. W., 1 Apr 2008, In : Journal of Clinical Pharmacology. 48, 4, p. 524-527 4 p.

Research output: Contribution to journalArticle

Nonlinear Dynamics
Statistical Models
Tissue Distribution
N-Methylaspartate
Biotransformation
2006
8 Citations (Scopus)

Altered methylprednisolone pharmacodynamics in healthy subjects with Histamine N-Methyltransferase C314T genetic polymorphism

Yuen, Y. H., Jusko, W. J., Spratlin, V. E. & Jann, M. W., 1 Apr 2006, In : Journal of Clinical Pharmacology. 46, 4, p. 408-417 10 p.

Research output: Contribution to journalArticle

Histamine N-Methyltransferase
Methylprednisolone
Genetic Polymorphisms
Healthy Volunteers
Genotype
2 Citations (Scopus)

Effect of thioridazine on gap junction intercellular communication in connexin 43-expressing cells

Matesic, D. F., Abifadel, D. N., Garcia, E. L. & Jann, M. W., 1 Jul 2006, In : Cell Biology and Toxicology. 22, 4, p. 257-268 12 p.

Research output: Contribution to journalArticle

Thioridazine
Connexin 43
Gap Junctions
Mesoridazine
Communication
6 Citations (Scopus)

Endogenous histamine and cortisol levels in subjects with different histamine N-methyltransferase C314T genotypes: A pilot study

Yuen, Y. H., Jusko, W. J., Zhou, H. H., Chen, G. L., Guo, D., Zhou, G., Spratlin, V. E. & Jann, M. W., 9 May 2006, In : Molecular Diagnosis and Therapy. 10, 2, p. 109-114 6 p.

Research output: Contribution to journalArticle

Histamine N-Methyltransferase
Histamine
Hydrocortisone
Genotype
Heterozygote
15 Citations (Scopus)

Lack of pharmacokinetic interaction between lamotrigine and olanzapine in healthy volunteers

Jann, M. W., Hon, Y. Y., Shamsi, S. A., Zheng, J., Awad, E. A. & Spratlin, V., 1 May 2006, In : Pharmacotherapy. 26, 5 I, p. 627-633 7 p.

Research output: Contribution to journalArticle

olanzapine
Healthy Volunteers
Pharmacokinetics
Bipolar Disorder
lamotrigine
11 Citations (Scopus)

Reduced methylprednisolone clearance causing prolonged pharmacodynamics in a healthy subject was not associated with CYP3A5*3 allele or a change in diet composition

Lee, S. J., Jusko, W. J., Salaita, C. G., Calis, K. A., Jann, M. W., Spratlin, V. E., Goldstein, J. A. & Yuen, Y. H., 1 May 2006, In : Journal of Clinical Pharmacology. 46, 5, p. 515-526 12 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Methylprednisolone
Healthy Volunteers
Alleles
Diet
2004
42 Citations (Scopus)

Development of capillary zone electrophoresis-electrospray ionization-mass spectrometry for the determination of lamotrigine in human plasma

Zheng, J., Jann, M. W., Hon, Y. Y. & Shamsi, S. A., 1 Jul 2004, In : Electrophoresis. 25, 13, p. 2033-2043 11 p.

Research output: Contribution to journalArticle

Plasma (human)
Electrospray ionization
Electrospray Ionization Mass Spectrometry
Capillary Electrophoresis
Electrophoresis
20 Citations (Scopus)

Dose-dependent alternations in the pharmacokinetics of olanzapine during coadministration of fluvoxamine in patients with schizophrenia

Chiu, C. C., Lane, H. Y., Huang, M. C., Liu, H. C., Jann, M. W., Hon, Y. Y., Chang, W. H. & Lu, M. L., 1 Dec 2004, In : Journal of Clinical Pharmacology. 44, 12, p. 1385-1390 6 p.

Research output: Contribution to journalArticle

olanzapine
Fluvoxamine
Schizophrenia
Pharmacokinetics
Cytochromes
2003
49 Citations (Scopus)

Correlation of cytochrome p450 (CYP) ia2 activity using caffeine phenotyping and olanzapine disposition in healthyvolunteers

Shirley, K. L., Hon, Y. Y., Penzak, S. R., Francis Lam, Y. W., Spratlin, V. & Jann, M. W., May 2003, In : Neuropsychopharmacology. 28, 5, p. 961-966 6 p.

Research output: Contribution to journalArticle

olanzapine
Caffeine
Cytochrome P-450 Enzyme System
Cytochrome P-450 CYP1A2
Saliva
2002
7 Citations (Scopus)

Clinical significance of drug binding, protein binding, and binding displacement drug interactions

Jann, M. W., 1 Jun 2002, In : Psychopharmacology bulletin. 36, 3, p. 22-41 20 p.

Research output: Contribution to journalArticle

Drug Interactions
Protein Binding
Antipsychotic Agents
Carrier Proteins
olanzapine
37 Citations (Scopus)

Effect of Seville orange juice and grapefruit juice on indinavir pharmacokinetics

Penzak, S. R., Acosta, E. P., Turner, M., Edwards, D. J., Hon, Y. Y., Desai, H. D. & Jann, M. W., 1 Oct 2002, In : Journal of Clinical Pharmacology. 42, 10, p. 1165-1170 6 p.

Research output: Contribution to journalArticle

Indinavir
Citrus paradisi
Pharmacokinetics
Cytochrome P-450 CYP3A
Cross-Over Studies
38 Citations (Scopus)

Influence of ritonavir on olanzapine pharmacokinetics in healthy volunteers

Penzak, S. R., Hon, Y. Y., Lawhorn, W. D., Shirley, K. L., Spratlin, V. & Jann, M. W., 5 Aug 2002, In : Journal of Clinical Psychopharmacology. 22, 4, p. 366-370 5 p.

Research output: Contribution to journalArticle

olanzapine
Ritonavir
Healthy Volunteers
Pharmacokinetics
HIV Protease Inhibitors
12 Citations (Scopus)

Pharmacokinetics of fluvoxamine in relation to CYP2C19 phenotype and genotype

Jann, M. W., ZumBrunnen, T. L., Kazmi, Y. R., VanDenBerg, C. M., Desai, H. D., Weidler, D. J. & Flockhart, D. A., 9 Oct 2002, In : Drug Metabolism and Drug Interactions. 19, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

Fluvoxamine
Pharmacokinetics
Genotype
Phenotype
Cytochrome P-450 CYP2D6
2001

Contemporary drug treatment

Corey-Bloom, J., Geldmacher, D. S. & Jann, M. W., 15 Feb 2001, In : Patient Care. 35, 3, p. 54-67 14 p.

Research output: Contribution to journalArticle

Cholinesterases
Dementia
Alzheimer Disease
Pharmaceutical Preparations
13 Citations (Scopus)

Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo

Lane, H. Y., Chiu, C. C., Kazmi, Y., Desai, H., Francis Lam, Y. W., Jann, M. W. & Chang, W. H., 1 Jan 2001, In : Drug Metabolism and Drug Interactions. 18, 3-4, p. 263-278 16 p.

Research output: Contribution to journalArticle

Citrus paradisi
Cytochrome P-450 CYP3A
Ketoconazole
Clozapine
Isoenzymes
29 Citations (Scopus)

Repeated ingestion of grapefruit juice does not alter clozapine's steady-state plasma levels, effectiveness, and tolerability

Lane, H. Y., Jann, M. W., Chang, Y. C., Chiu, C. C., Huang, M. C., Lee, S. H. & Chang, W. H., 1 Jan 2001, In : Journal of Clinical Psychiatry. 62, 10, p. 812-817 6 p.

Research output: Contribution to journalArticle

Citrus paradisi
Clozapine
Eating
Cytochrome P-450 CYP3A
Cytochrome P-450 CYP1A2
80 Citations (Scopus)

Seville (sour) orange juice: Synephrine content and cardiovascular effects in normotensive adults

Penzak, S. R., Jann, M. W., Cold, J. A., Hori, Y. Y., Desai, H. D. & Gurley, B. J., 1 Jan 2001, In : Journal of Clinical Pharmacology. 41, 10, p. 1059-1063 5 p.

Research output: Contribution to journalArticle

Synephrine
Octopamine
Eating
Hemodynamics
Nasal Decongestants

The Impact of Cloning in Pharmaceutical Products and for Human Therapeutics

Jann, M. W., Shirley, K. L. & Falek, A., 1 Jan 2001, In : Global Bioethics. 14, 2-3, p. 47-51 5 p.

Research output: Contribution to journalArticle

Open Access
pharmaceutical
Organism Cloning
Pharmaceutical Preparations
drug
Disease
2000

An international symposium on psychopharmacology and ethnicity

Jann, M. W. & Montane Jaime, L. K., 1 Jan 2000, In : Drug Metabolism and Drug Interactions. 16, 1, p. 13-14 2 p.

Research output: Contribution to journalArticle

Psychopharmacology
31 Citations (Scopus)

Clozapine pharmacokinetics and pharmacodynamics studied with CYP1A2-null mice

Aitchison, K. J., Jann, M. W., Zhao, J., Sakai, T., Zaher, H., Wolff, K., Collier, D., Kerwin, R. W. & Gonzalez, F. J., 1 Jan 2000, In : Journal of Psychopharmacology. 14, 4, p. 353-359 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP1A2
Clozapine
Pharmacokinetics
Area Under Curve
Myoclonus
6 Citations (Scopus)

Disposition of olanzapine in Chinese schizophrenic patients

Lane, H. Y., Liu, H. C., Vandenberg, C. M., Su, M. H., Jann, M. W. & Chang, W. H., 1 Jan 2000, In : International Journal of Clinical Pharmacology and Therapeutics. 38, 10, p. 482-485 4 p.

Research output: Contribution to journalArticle

olanzapine
Population
Half-Life
87 Citations (Scopus)

Fluvoxamine reduces the clozapine dosage needed in refractory schizophrenic patients

Lu, M. L., Lane, H. Y., Chen, K. P., Jann, M. W., Su, M. H. & Chang, W. H., 1 Jan 2000, In : Journal of Clinical Psychiatry. 61, 8, p. 594-599 6 p.

Research output: Contribution to journalArticle

Fluvoxamine
Clozapine
norclozapine
Schizophrenia
Therapeutics

Pharmacogenetics and Pharmacogenomics: Public Policy and Bioethical Issues Associated with Patents for Drug Development

Falek, A. & Jann, M. W., 1 Jan 2000, In : Global Bioethics. 13, 3-4, p. 29-42 14 p.

Research output: Contribution to journalArticle

Open Access
Bioethical Issues
Patents
Pharmacogenetics
Public Policy
patent
18 Citations (Scopus)

Pharmacokinetics of three formulations of ondansetron hydrochloride in healthy volunteers: 24-mg oral tablet, rectal suppository, and i.v. infusion

Vandenberg, C. M., Kazmi, Y., Stewart, J., Weidler, D. J., Tenjarla, S. N., Ward, E. S. & Jann, M. W., 1 Jun 2000, In : American Journal of Health-System Pharmacy. 57, 11, p. 1046-1050 5 p.

Research output: Contribution to journalArticle

Ondansetron
Suppositories
Tablets
Healthy Volunteers
Pharmacokinetics
3 Citations (Scopus)

Supportive care for the patient with Alzheimer's disease.

Jann, M. W. & Brandt, N., 1 Jan 2000, In : Journal of the American Pharmaceutical Association (Washington,D.C. : 1996). 40, 5 Suppl 1

Research output: Contribution to journalArticle

Rivastigmine
Tacrine
Cholinesterase Inhibitors
Long-Term Care
Genetic Predisposition to Disease
29 Citations (Scopus)
Pharmacogenetics
Antidepressive Agents
Isoenzymes
Cytochrome P-450 CYP2D6
Drug Interactions
1999
122 Citations (Scopus)

Effects of gender and age on plasma levels of clozapine and its metabolites: Analyzed by critical statistics

Lane, H. Y., Chang, Y. C., Chang, W. H., Lin, S. K., Tseng, Y. T. & Jann, M. W., Jan 1999, In : Journal of Clinical Psychiatry. 60, 1, p. 36-40 5 p.

Research output: Contribution to journalArticle

norclozapine
Clozapine
Body Weight
Oxides
Linear Models
10 Citations (Scopus)

Efficacy and safety of a loading-dose regimen versus a no-loading-dose regimen of metrifonate in the symptomatic treatment of Alzheimer's disease: A randomized, double-masked, placebo-controlled trial

Jann, M. W., Cyrus, P. A., Eisner, L. S., Margolin, D. I., Griffin, T. & Gulanski, B., 1 Jan 1999, In : Clinical Therapeutics. 21, 1, p. 88-102 15 p.

Research output: Contribution to journalArticle

Trichlorfon
Alzheimer Disease
Placebos
Safety
Therapeutics
41 Citations (Scopus)

In-vitro and in-vivo evaluation of the drug-drug interaction between fluvoxamine and clozapine

Chang, W. H., Augustin, B., Lane, H. Y., ZumBrunnen, T., Liu, H. C., Kazmi, Y. & Jann, M. W., 29 Jul 1999, In : Psychopharmacology. 145, 1, p. 91-98 8 p.

Research output: Contribution to journalArticle

Fluvoxamine
Drug Evaluation
Clozapine
Drug Interactions
norclozapine
1998
9 Citations (Scopus)

Economic considerations and formulary management of oral antipsychotics

Jann, M. W. & Cohen, L. J., 5 May 1998, In : Disease Management and Health Outcomes. 3, 3, p. 115-129 15 p.

Research output: Contribution to journalArticle

Formularies
Clozapine
Antipsychotic Agents
Economics
Schizophrenia
9 Citations (Scopus)

Increased lithium serum and red blood cell concentrations during ketorolac coadministration

Cold, J. A., Zumbrunnen, T. L., Simpson, M. A., Augustin, B. G., Awad, E. & Jann, M. W., 1 Feb 1998, In : Journal of Clinical Psychopharmacology. 18, 1, p. 33-37 5 p.

Research output: Contribution to journalArticle

Ketorolac
Lithium
Erythrocytes
Serum
Drug Interactions
23 Citations (Scopus)

Pharmacology and clinical efficacy of cholinesterase inhibitors

Jann, M. W., 1 Nov 1998, In : American Journal of Health-System Pharmacy. 55, 21 SUPPL., p. S22-S25

Research output: Contribution to journalArticle

Cholinesterase Inhibitors
Trichlorfon
Pharmacology
Alzheimer Disease
Tacrine
20 Citations (Scopus)

Relative bioavailability of ondansetron 8-mg oral tablets versus two extemporaneous 16-mg suppositories: Formulation and gender differences

Jann, M. W., ZumBrunnen, T. L., Tenjarla, S. N., Ward, E. S. & Weidler, D. J., 1 Mar 1998, In : Pharmacotherapy. 18, 2 I, p. 288-294 7 p.

Research output: Contribution to journalArticle

Ondansetron
Suppositories
Biological Availability
Tablets
Area Under Curve
59 Citations (Scopus)

Reversible metabolism of clozapine and clozapine N-oxide in schizophrenic patients

Chang, W. H., Lin, S. K., Lane, H. Y., Wei, F. C., Hu, W. H., Lam, Y. W. F. & Jann, M. W., 1 Jul 1998, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 22, 5, p. 723-739 17 p.

Research output: Contribution to journalArticle

Clozapine
Pharmacokinetics
clozapine N-oxide
1997
18 Citations (Scopus)

Blood levels of reduced haloperidol versus clinical efficacy and extrapyramidal side effects of haloperidol

Lane, H. Y., Lin, H. N., Hu, O. Y. P., Chen, C. C., Jann, M. W. & Chang, W. H., 1 Feb 1997, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 21, 2, p. 299-311 13 p.

Research output: Contribution to journalArticle

Haloperidol
Erythrocytes
Pharmaceutical Preparations
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol
Inpatients
46 Citations (Scopus)

Clozapine dosages and plasma drug concentrations

Chang, W. H., Lin, S. K., Lane, H. Y., Hu, W. H., Jann, M. W. & Lin, H. N., 1 Aug 1997, In : Journal of the Formosan Medical Association. 96, 8, p. 599-605 7 p.

Research output: Contribution to journalArticle

Clozapine
Pharmaceutical Preparations
Schizophrenia
Social Adjustment
Drug Monitoring
32 Citations (Scopus)

Dextromethorphan phenotyping and haloperidol disposition in schizophrenic patients

Lane, H. Y., Hu, O. Y. P., Jann, M. W., Deng, H. C., Lin, H. N. & Chang, W. H., 24 Mar 1997, In : Psychiatry Research. 69, 2-3, p. 105-111 7 p.

Research output: Contribution to journalArticle

Dextromethorphan
Haloperidol
Dextrorphan
Psychotropic Drugs
Antipsychotic Agents
6 Citations (Scopus)

Dose-dependent reduced haloperidol/haloperidol ratios: Influence of patient-related variables

Lane, H. Y., Chang, W. H., Chang, Y. C., Hu, O. Y. P., Lin, H. N., Jann, M. W. & Hu, W. H., 19 Sep 1997, In : Psychiatry Research. 72, 2, p. 127-132 6 p.

Research output: Contribution to journalArticle

Haloperidol
Body Weight
4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanol
Inpatients
16 Citations (Scopus)

Gender differences in plasma clozapine levels and its metabolites in schizophrenic patients

Jann, M. W., Liu, H. C., Wei, F. C., Lin, S. K., Lin, S. K., Hu, W. H. & Chang, W. H., 1 Sep 1997, In : Human Psychopharmacology. 12, 5, p. 489-495 7 p.

Research output: Contribution to journalArticle

Clozapine
Brief Psychiatric Rating Scale
Haloperidol
High Pressure Liquid Chromatography
Incidence

In vitro metabolism of clozapine in human hepatic microsomes

Augustin, B. G., Thurston, A., Thomas, G., Hui, J. & Jann, M. W., 1 Dec 1997, In : Clinical Pharmacology and Therapeutics. 61, 2, 1 p.

Research output: Contribution to journalArticle

Clozapine
Microsomes
Liver
In Vitro Techniques
Glucose-6-Phosphate
7 Citations (Scopus)

Plasma alpha-one acid glycoprotein and haloperidol concentrations in schizophrenic patients

Jann, M. W., Crabtree, B. L., Pitts, W. M., Lam, F. & Carter, G., 1 Jan 1997, In : Neuropsychobiology. 36, 1, p. 32-36 5 p.

Research output: Contribution to journalArticle

Haloperidol
Brief Psychiatric Rating Scale
Glycoproteins
Acids
Placebos
1996
14 Citations (Scopus)

A practical loading dose method for converting schizophrenic patients from oral to depot haloperidol therapy

Wei, F. C., Jann, M. W., Lin, H. N., Piao-Chien, C. & Chang, W. H., 1 Jul 1996, In : Journal of Clinical Psychiatry. 57, 7, p. 298-302 5 p.

Research output: Contribution to journalArticle

Haloperidol
Decanoates
Therapeutics
Injections
Nursing Staff
1 Citation (Scopus)

Disposition of remoxipride in Chinese schizophrenic patients

Lin, S. K., Chang, W. H., Chien, C. P., Lam, Y. W. F. & Jann, M. W., 23 Jan 1996, In : International Journal of Clinical Pharmacology and Therapeutics. 34, 1, p. 17-20 4 p.

Research output: Contribution to journalArticle

Remoxipride
Area Under Curve
Half-Life